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Cell Biology of the Ovary : Stem Cells, Development, Cancer, and Clinical Aspects

https://libcat.nshealth.ca/en/permalink/provcat43117
Hidetaka Katabuchi, Takashi Ohba, Takeshi Motohara, editors. --Singapore: Springer , c2018.
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This unique compilation focuses on a very curious organ, the ovary. There are still many unknown facts about the origins of ovarian tissue and ovarian cancer, and each chapter describes in detail the latest insights into the ovary from basic to clinical aspects. Expert authors reveal the most recent findings on ovariogenesis and ovarian carcinogenesis by shedding light on stem cell biology for the ovarian surface epithelial cells or primordial germ cells. Readers will greatly increase their und…
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Other Authors
Katabuchi, Hidetaka
Ohba, Takashi
Motohara, Takeshi
Responsibility
Hidetaka Katabuchi, Takashi Ohba, Takeshi Motohara, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (viii, 166 p.) : 32 illus., 24 illus. in color
ISBN
9789811079412
9789811079405 (print ed.)
9789811079429 (print ed.)
9789811340239 (print ed.)
Subjects (MeSH)
Ovarian Neoplasms - pathology
Ovary - cytology
Stem Cells - cytology
Specialty
Cell Biology
Gynecology
Abstract
This unique compilation focuses on a very curious organ, the ovary. There are still many unknown facts about the origins of ovarian tissue and ovarian cancer, and each chapter describes in detail the latest insights into the ovary from basic to clinical aspects. Expert authors reveal the most recent findings on ovariogenesis and ovarian carcinogenesis by shedding light on stem cell biology for the ovarian surface epithelial cells or primordial germ cells. Readers will greatly increase their understanding of the relevance of the cells that constitute the ovary, which is of vast significance in comprehending the occurrence mechanism of ovarian tissue and ovarian cancer. In this way the book covers a wide range of fields concerned with the ovary. This work benefits not only gynecologists and obstetricians, but also basic researchers in the field of stem cell biology and all clinicians who are involved in the management of fertility preservation or ovarian cancer.
Contents
1. Reconstitution of Germ Cell Development In Vitro -- 2. The Role of Hedgehog-BMP4 Signaling in the Patterning of Coelomic Mesoderm and the Onset of Gonadogenesis -- 3. Regulation of Metabolic Pathways in Steroidogenic Cells by Ad4BP/SF-1 -- 4. Role of Lgr5-Expressing Stem Cells in Epithelial Renewal and Cancer in the Reproductive Tract -- 5. Tumor-Initiating Cells in Ovarian Cancer -- 6. Emerging Role of CD44 Variant 6 in Driving the Metastatic Journey of Ovarian Cancer Stem Cells -- 7. Clinical Management of Primary Ovarian Insufficiency -- 8. Rescue for Primary Ovarian Insufficiency -- 9. Current Status of Ovarian Tissue Vitrification as a Fertility Preservation for the Young Cancer Patients -- 10. Molecular Pathogenesis of Ovarian Cancer: An Inextricable Maze -- 11. Clinical Management of Epithelial Ovarian Cancer -- 12. Molecular Targeted Therapy for Epithelial Ovarian Cancer.
Format
e-Book
Location
Online
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Molecular Diagnosis and Targeting for Gynecologic Malignancy

https://libcat.nshealth.ca/en/permalink/provcat46711
Seiji Isonishi, Yoshihiro Kikuchi. Springer , 2021.
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Location
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Responsibility
Seiji Isonishi, Yoshihiro Kikuchi
Publisher
Springer
Date of Publication
2021
Physical Description
1 online resource (viii, 165 pages) : illustrations
Series Title
Current human cell research and applications
ISBN
9789813360136
Specialty
Gynecology
Medical Oncology
Cell Biology
Format
e-Book
Location
Online
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