Hepatitis C Virus II : Infection and Disease
https://libcat.nshealth.ca/en/permalink/provcat40421
Tatsuo Miyamura, Stanley M. Lemon, Christopher M. Walker, Takaji Wakita, editors.
--Tokyo:
Springer Japan
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book helps scientists, clinicians and other interested individuals understand recent clinical advances and challenges for the future. It covers many basic aspects of the pathogenesis of chronic hepatitis C, HCV infections in particular populations, approaches to therapy, and prevention and control of HCV Infection. The book provides a succinct review of the large amount of data generated by multiple groups over the past two decades that has revealed the natural history of HCV infection. Si…
- Available Online
- View e-Book
- Other Authors
- Miyamura, Tatsuo
- Lemon, Stanley M
- Walker, Christopher M
- Wakita, Takaji
- Responsibility
- Tatsuo Miyamura, Stanley M. Lemon, Christopher M. Walker, Takaji Wakita, editors
- Place of Publication
- Tokyo
- Publisher
- Springer Japan
- Date of Publication
- c2016
- Physical Description
- 1 online resource (ix, 372 p. : 25 illus., 23 illus. in color)
- ISBN
- 9784431561019
- 9784431560999 (print ed.)
- Subjects (MeSH)
- Antiviral Agents - therapeutic use
- Hepatitis C, Chronic
- Hepatitis C Virus
- Specialty
- Gastroenterology
- Virology
- Abstract
- This book helps scientists, clinicians and other interested individuals understand recent clinical advances and challenges for the future. It covers many basic aspects of the pathogenesis of chronic hepatitis C, HCV infections in particular populations, approaches to therapy, and prevention and control of HCV Infection. The book provides a succinct review of the large amount of data generated by multiple groups over the past two decades that has revealed the natural history of HCV infection. Similarly, it summarizes current understanding of the origins of HCV-associated hepatocellular carcinoma, cirrhosis and hepatic fibrosis. Extra-hepatic manifestation and metabolic disorders related to HCV infection are described. In this volume, these clinically important aspects of HCV infection are comprehensively described. Highlights are description of newly developed direct- acting antivirals. The authors represent a worldwide distribution of leaders in the field reflecting the global nature of HCV infection. Based on recent data concerning the genetic- and geographical diversity of HCV, and increased global disease burden of HCV infection, challenges for global control of HCV infections are described.
- Contents
- Part I. Chronic Hepatitis C -- Natural History of Chronic Hepatitis C -- The Multifaceted Features of HCV Infection Beyond the Liver -- Hepatic Fibrosis in Hepatitis C -- Hepatocellular Carcinoma and Hepatitis C Virus -- HCV, Alcohol, and the Liver -- Extrahepatic Replication of HCV -- Part II. HCV Infections in Special Populations -- Hepatitis C Virus Infection in Pregnancy and Childhood -- Part III. Approaches to Therapy -- Host Genetics and Responses to Antiviral Therapy in Chronic Hepatitis C -- Viral Variation and Response to Therapy -- HCV NS3/4A Protease Inhibitors and the Road to Effective Direct-Acting Antiviral Therapies -- Mechanism of Action of Direct-Acting Antivirals: New Insights into the HCV Life Cycle -- Modeling HCV Dynamics in Clinical Practice to Personalize Antiviral Therapy -- Part IV. Prevention and Control of HCV Infection -- Prophylactic Vaccines for the Hepatitis C Virus -- Global Control of Hepatitis C Virus Infection.
- Format
- e-Book
- Location
- Online
