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Colitis-Associated Cancer

https://libcat.nshealth.ca/en/permalink/provcat40391
Masato Kusunoki, editor. (1st ed.) --Tokyo: Springer Japan , c2016.
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As the number of patients with colitis-associated cancer (CAC) is on the increase, the purpose of this book is to review the latest topics concerning management of the disease. In recent years, the diagnostic power of endoscopy and molecular pathology has also grown tremendously, as a result of which they now have a far greater influence on the treatment of CAC. At the moment, appropriate monitoring programs for ulcerative colitis and Crohn's disease remain uncertain. At the same time, the late…
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Other Authors
Kusunoki, Masato
Responsibility
Masato Kusunoki, editor
Edition
1st ed.
Place of Publication
Tokyo
Publisher
Springer Japan
Date of Publication
c2016
Physical Description
1 online resource (viii, 150 p. : 21 illus., 15 illus. in color)
ISBN
9784431555223
9784431555216 (print ed.)
Subjects (MeSH)
Colitis - complications
Colonic Neoplasms - etiology
Inflammatory Bowel Diseases
Abstract
As the number of patients with colitis-associated cancer (CAC) is on the increase, the purpose of this book is to review the latest topics concerning management of the disease. In recent years, the diagnostic power of endoscopy and molecular pathology has also grown tremendously, as a result of which they now have a far greater influence on the treatment of CAC. At the moment, appropriate monitoring programs for ulcerative colitis and Crohn's disease remain uncertain. At the same time, the latest findings on DNA methylation and microRNAs hold the promise of making revolutionary changes in these areas. Moreover, recent drug advances in the treatment of inflammatory bowel diseases have changed surgical indications. On the other hand, the indication of mucosectomy on colorectal cancer in ulcerative colitis and prophylactic abdominoperineal resection for Crohn's disease remain controversial. This book provides the latest information on the remaining issues of CAC from the point of view of expert surgeons.
Contents
1. Colitis-Associated Cancer: Overview -- Part I. Clinical Features -- 2. Incidence and Risk Factors -- 3. Prevention and Prognosis -- Part II. Diagnosis -- 4. Cancer Surveillance of Patients with Long-Standing Inflammatory Bowel Disease -- 5. Molecular Alterations in Inflammatory Colonic Carcinogenesis and Markers for Detecting Colitis-Associated Cancer -- Part III. Surgical Treatment -- 6. Surgical Treatment for Ulcerative Colitis-Associated Cancer or Dysplasia -- 7. Surgical Treatment for Colorectal Cancer in Crohn's Disease.
Format
e-Book
Location
Online
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Treatment of Inflammatory Bowel Disease with Biologics

https://libcat.nshealth.ca/en/permalink/provcat42935
edited by Adam S. Cheifetz, Joseph D. Feuerstein. --Cham, Switzerland: Springer , c2018.
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This book is a concise yet comprehensive overview of the use of biologics for the treatment of Crohn's disease and ulcerative colitis. The volume details how best to utilize these medications in order to optimize their efficacy and safety, as well as how to understand, recognize, and treat complications that may arise from using biologics to treat IBD. The text also focuses on new data, novel biologics, and biosimilars of this rapidly expanding field. Written by experts in the field, Treatment …
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Other Authors
Cheifetz, Adam S.
Feuerstein, Joseph D.
Responsibility
edited by Adam S. Cheifetz, Joseph D. Feuerstein
Place of Publication
Cham, Switzerland
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xi, 335 p.) : 22 illus., 19 illus. in color
ISBN
9783319602769
9783319602752 (print ed.)
9783319602776 (print ed.)
9783319868233 (print ed.)
Subjects (MeSH)
Anti-Inflammatory Agents - therapeutic use
Biological Products - therapeutic use
Inflammatory Bowel Diseases - drug therapy
Specialty
Biological Therapy
Gastroenterology
Abstract
This book is a concise yet comprehensive overview of the use of biologics for the treatment of Crohn's disease and ulcerative colitis. The volume details how best to utilize these medications in order to optimize their efficacy and safety, as well as how to understand, recognize, and treat complications that may arise from using biologics to treat IBD. The text also focuses on new data, novel biologics, and biosimilars of this rapidly expanding field. Written by experts in the field, Treatment of Inflammatory Bowel Disease with Biologics is a valuable resource for gastroenterologists, allied health professionals, fellows, and trainees who treat patients with inflammatory bowel disease.
Contents
Mechanism of Action and Pharmacokinetics of Biologics -- Anti-tumor Necrosis Factor Agents in Ulcerative Colitis -- Anti-tumor Necrosis Factor Agents in Crohn's Disease -- Anti-TNF Therapy for Treatment of Extraintestinal Manifestations of Inflammatory Bowel Disease -- Use of Biologics in the Postoperative Management of Crohn's Disease -- Biologics in Pregnancy and Breastfeeding -- Concomitant Use of Immunosuppressive Therapy with Tumor Necrosis Factor (TNF) Antagonists in Inflammatory Bowel Disease -- Therapeutic Drug Monitoring of Biologic Agents -- Use of Biologics in Crohn's Disease and Ulcerative Colitis Prior to Surgery and Perioperative Risks -- Cessation of Biologics—Can it be Done? -- Biologic Therapy in Pediatric Inflammatory Bowel Disease -- Infectious Complications of Biologics -- Tumor Necrosis Factor-Alpha Inhibitors and Risks of Malignancy -- Non-infectious and Non-malignant Complications of Biologics -- Biosimilars in Inflammatory Bowel Disease 2017: State of the Science, State of the Art, State of the Finances -- Anti-Integrin Agents in IBD: Efficacy and Risk of Complications -- Novel Agents in Inflammatory Bowel Disease -- Quality, Safety, and Practical Considerations of Using Biologic Therapies.
Format
e-Book
Location
Online
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