Insulin Resistance and Cancer : Epidemiology, Cellular and Molecular Mechanisms and Clinical Implications
https://libcat.nshealth.ca/en/permalink/provcat28493
edited by I. George Fantus.
--New York, NY:
Springer Science+Business Media
, c2011.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Fantus, I. George
- Responsibility
- edited by I. George Fantus
- Place of Publication
- New York, NY
- Publisher
- Springer Science+Business Media
- Date of Publication
- c2011
- Series Vol.
- 1
- Series Title
- Energy balance and cancer
- ISBN
- 9781441999115
- Subjects (MeSH)
- Insulin Resistance
- Neoplasms - epidemiology
- Neoplasms - therapy
- Obesity - complications
- Subjects (LCSH)
- Oncology
- Endocrinology
- Format
- e-Book
- Location
- Online
Insulin Resistance and Polycystic Ovarian Syndrome : Pathogenesis, Evaluation, and Treatment
https://libcat.nshealth.ca/en/permalink/provcat30033
edited by Evanthia Diamanti-Kandarakis, John E. Nestler, Dimitrios Panidis, Renato Pasquali.
--Totowa, NJ:
Humana Press
, c2007.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Other Authors
- Nestler, John E
- Panidis, Dimitrios
- Pasquali, Renato
- Responsibility
- edited by Evanthia Diamanti-Kandarakis, John E. Nestler, Dimitrios Panidis, Renato Pasquali
- Place of Publication
- Totowa, NJ
- Publisher
- Humana Press
- Date of Publication
- c2007
- Series Title
- Contemporary endocrinology (Totowa, N.J.)
- ISBN
- 9781597453103
- Subjects (MeSH)
- Insulin Resistance
- Polycystic Ovary Syndrome
- Metabolic Syndrome X
- Subjects (LCSH)
- Gynecology
- Endocrinology
- Format
- e-Book
- Location
- Online
Insulin Resistance : Childhood Precursors and Adult Disease
https://libcat.nshealth.ca/en/permalink/provcat40633
Philip Scott Zeitler, Kristen J. Nadeau, editors.
--Totowa, NJ:
Humana Press
, c2008.
- Available Online
- View e-Book
- Location
- Online
The prevalence of disorders related to insulin resistance has continued to increase throughout the developed and developing world. The world's population has continued to become more obese and sedentary. Of great concern in the last decade is the extension of these deleterious lifestyle patterns to the pediatric population, leading to both obesity and the appearance of insulin resistance-related disorders in youth as well as adults. Insulin Resistance: Childhood Precursors and Adult Disease pre…
- Available Online
- View e-Book
- Other Authors
- Zeitler, Philip Scott, 1957-
- Nadeau, Kristen J
- Responsibility
- Philip Scott Zeitler, Kristen J. Nadeau, editors
- Place of Publication
- Totowa, NJ
- Publisher
- Humana Press
- Date of Publication
- c2008
- Physical Description
- 1 online resource (xi, 331 p. : [8] p. of plates : ill.)
- Series Title
- Contemporary endocrinology
- ISBN
- 9781597451925
- 9781588298751 (print ed.)
- Subjects (MeSH)
- Insulin Resistance
- Abstract
- The prevalence of disorders related to insulin resistance has continued to increase throughout the developed and developing world. The world's population has continued to become more obese and sedentary. Of great concern in the last decade is the extension of these deleterious lifestyle patterns to the pediatric population, leading to both obesity and the appearance of insulin resistance-related disorders in youth as well as adults. Insulin Resistance: Childhood Precursors and Adult Disease presents topics related to insulin resistance and its consequences across the lifespan. In the first section of the book examining epidemiology, the contributors review controversies over the definition of metabolic syndrome in adults and children, current knowledge regarding the epidemiology of insulin resistance in the pediatric population and the contributions of the prenatal and early childhood environment to the development of insulin resistance. The Second part of the book explores pathophysiology, with reviews of the techniques used to study insulin resistance, as well as current knowledge of the molecular and physiologic mechanisms of insulin resistance, including the contributions of adipose tissue and biochemical mediators. This section concludes with discussion of the relationship between insulin resistance and cardiovascular, endothelial, liver and gonadal disorders. The final section of the book explores the impact of exercise and weight loss medications on insulin resistance. Insulin resistance is likely to be the most important public health concern in many parts of the world in coming decades. This volume provides up-to-date reviews of these areas, providing the reader with a current perspective on issues in insulin resistance as they affect patients across the lifespan. The hope for Insulin Resistance: Childhood Precursors and Adult Disease is that it will spur continued interest in the topic on the part of clinicians and researchers, perhaps promoting new points of view and creative approaches to a daunting challenge.
- Contents
- Part I. Epidemiology -- The Metabolic Syndrome: Definitions, Controversies and Clinical Utility -- Epidemiology of the Metabolic Syndrome and Related Disorders in Children and Adolescents -- Metabolic Syndrome in Children and Adolescents Worldwide -- Maternal-Fetal Contributors to the Insulin Resistance Syndrome in Youth -- Early Childhood Contributions to Insulin Resistance -- Part II. Pathophysiology -- Molecular Mechanisms of Insulin Resistance -- Techniques Used to Assess Insulin Action -- Adiposity is The Enemy: Body Composition and Insulin Sensitivity -- Ectopic Fat Deposition, Adiponectin and Insulin Resistance in Obese Adolescents -- Mediators of Insulin Resistance -- Insulin Resistance and the Pathogenesis of Cardiovascular Disease -- Insulin Resistance and Cardiovascular Disease -- The Liver and Insulin Resistance: The Important Convergence of Endocrinology and Hepatology -- Polycystic Ovary Syndrome and Metabolic Syndrome -- Part III. Treatment -- Effects of Exercise in Metabolic Syndrome and Diabetes: A Central Role for Insulin Sensitivity -- Weight Loss Medications and the Metabolic Syndrome.
- Format
- e-Book
- Location
- Online
Insulin Resistance : Childhood Precursors of Adult Disease
https://libcat.nshealth.ca/en/permalink/provcat45108
Philip S. Zeitler, Kristen J. Nadeau, editors.
(Second edition)
--Cham:
Humana Press
, c2020.
- Available Online
- View e-Book
- Location
- Online
Now in a revised and expanded second edition, this unique text presents topics related to insulin resistance in youth and its consequences across the lifespan. In the first section of the book examining epidemiology, the contributors review controversies over the definition of insulin resistance in children and what is known about how insulin resistance in youth differs from adults, the measurement of insulin resistance in youth in the research and clinical settings, and current knowledge regar…
- Available Online
- View e-Book
- Other Authors
- Zeitler, Philip S.
- Nadeau, Kristen J.
- Responsibility
- Philip S. Zeitler, Kristen J. Nadeau, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xvi, 356 p.) : 41 illus., 19 illus. in color
- Series Title
- Contemporary endocrinology
- ISBN
- 9783030250577
- 9783030250553 (Print ed.)
- 9783030250560 (Print ed.)
- ISSN
- 2523-3785
- Subjects (MeSH)
- Insulin Resistance
- Specialty
- Endocrinology
- Abstract
- Now in a revised and expanded second edition, this unique text presents topics related to insulin resistance in youth and its consequences across the lifespan. In the first section of the book examining epidemiology, the contributors review controversies over the definition of insulin resistance in children and what is known about how insulin resistance in youth differs from adults, the measurement of insulin resistance in youth in the research and clinical settings, and current knowledge regarding the epidemiology of insulin resistance in the pediatric population. The second section of the book explores pathophysiology, including current knowledge of the molecular, metabolic, and physiologic mechanisms of insulin resistance, the unique pathophysiology of pregnancy and puberty, the contributions of the prenatal and early childhood environment to the development of insulin resistance, and adipose and biochemical mediators. This section concludes with discussion of the relationship between insulin resistance and cardiovascular disease and liver disorders. A third section, new to this second edition, explores insulin resistance in unique models: intrauterine growth restriction and girls with polycystic ovary syndrome and metabolic syndrome. The final section of the book explores the concepts of treatment through medications directed at insulin sensitivity, as well as exercise, weight loss medications and consequences of bariatric surgery. Insulin Resistance: Childhood Precursors of Adult Disease, Second Edition provides up-to-date reviews of all of these areas, providing the reader with a current perspective on issues in insulin resistance in youth, an emerging risk factor for disease across the lifespan, that will spur continued interest in the topic on the part of clinicians and researchers, perhaps promoting new points of view and creative approaches to this daunting challenge.
- Contents
- Part I: Definition and Epidemiology -- Clinical Manifestations of Insulin Resistance in Youth -- Techniques to Assess Insulin Action in Youth -- Insulin Resistance in Chronic Disease -- Part II: Pathophysiology -- Molecular Mechanisms of Insulin Resistance -- Insulin Resistance in Pregnancy: Implications for Mother and Offspring -- Maternal-Fetal Contributors to Insulin Resistance Syndrome in Youth -- Early Childhood Contributions to Insulin Resistance -- Insulin Resistance in Puberty -- Adiposity Is the Enemy: Body Composition and Insulin Sensitivity -- Ectopic Fat and Insulin Resistance in Youth -- Biomarkers of Insulin Resistance -- Insulin Resistance and Cardiovascular Disease -- The Liver and Insulin Resistance: The Important Convergence of Endocrinology and Hepatology -- Insulin Resistance and the Kidney in Youth -- Part III: Unique Models of Insulin Resistance in Youth -- Intrauterine Growth Restriction and Insulin Resistance -- Polycystic Ovary Syndrome and Metabolic Syndrome -- Part IV: Treatment -- Is Insulin Resistance a Treatment Target?- Exercise in Metabolic Syndrome and Diabetes: A Central Role for Insulin Sensitivity -- Weight Loss Medications in Adolescents -- Adolescent Metabolic/Bariatric Surgery: Effects on Obesity, Comorbidities, and Insulin Resistance.
- Format
- e-Book
- Location
- Online
Lipoproteins in diabetes mellitus
https://libcat.nshealth.ca/en/permalink/provcat33571
Alicia J. Jenkins, Peter P. Toth, Timothy J. Lyon, editors.
--New York:
Humana Press
, c2014.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Other Authors
- Jenkins, Alicia J
- Toth, Peter P
- Lyons, Timothy J
- Responsibility
- Alicia J. Jenkins, Peter P. Toth, Timothy J. Lyon, editors
- Place of Publication
- New York
- Publisher
- Humana Press
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xiv, 466 pages)
- Series Title
- Contemporary diabetes
- ISBN
- 9781461475545 (electronic bk.)
- 9781461475538
- Subjects (MeSH)
- Diabetes Complications
- Diabetes Mellitus - blood
- Insulin Resistance
- Lipoproteins - metabolism
- Subjects (LCSH)
- Diabetes
- Diabetes - Molecular aspects
- Lipoproteins
- Contents
- 1. Laboratory Assessment of Lipoproteins in Diabetes -- 2. Lipoprotein Subclasses and Cardiovascular Disease Risk in Insulin-Resistant Diabetes -- 3. Insulin Resistance and Atherosclerosis -- 4. Apoproteins and Cell Surface Receptors Regulating Lipoprotein Metabolism in the Setting of Type 2 Diabetes -- 5. Lipoprotein Metabolism and Alterations Induced by Insulin Resistance and Diabetes -- 6. Production and Metabolism of Triglyceride-Rich Lipoproteins in Both the Normal and Diabetic States -- 7. Lipoprotein(a): Structure, Metabolism, and Pathophysiology -- 8. Lipoprotein Glycation in Diabetes Mellitus -- 9. Lipoprotein (LDL and HDL) Oxidation in Diabetes Mellitus -- 10. The Role of Modified Forms of LDL and Corresponding Autoantibodies in the Development of Complications in Diabetes -- 11. Lipid: Extracellular Matrix Interactions as Therapeutic Targets in the Atherosclerosis of Diabetes -- 12. Tools for Assessing Lipoprotein Metabolism in Diabetes Mellitus -- 13. Endothelial Dysfunction and Dyslipidemia in Type 2 Diabetes: Pathogenesis, Significance and Therapy -- 14. Lipoproteins and Diabetic Nephropathy -- 15. Roles of Extravasated and Modified Plasma Lipoproteins in Diabetic Retinopathy -- 16. Effects of Lifestyle (Diet, Plant Sterols, Exercise) and Glycemic Control on Lipoproteins in Diabetes -- 17. About Randomised Clinical Trials Related to Lipoproteins in Diabetes Mellitus -- 18. Statin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients -- 19. The PPAR System in Diabetes -- 20. Fibrate Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients -- 21. Niacin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients -- 22. Cholesterol Absorption Inhibitors (Ezetimibe) and Bile Acid Binding Resins (Colesevelam HCl) as Therapy for Dyslipidemia in Patients with Diabetes Mellitus -- 23. Emerging Lipoprotein-Related Therapeutics for Patients with Diabetes.
- Format
- e-Book
- Location
- Online
