ABC of kidney disease
https://libcat.nshealth.ca/en/permalink/provcat23663
Goldsmith, David.
--Malden, MA:
Blackwell Pub. | BMJ Books
, 2007.
- Call Number
- WJ 300 A134 2007
- Location
- Dickson Building
- Call Number
- WJ 300 A134 2007
- Author
- Goldsmith, David
- Other Authors
- Jayawardene, Satish
- Ackland, Penny
- Place of Publication
- Malden, MA
- Publisher
- Blackwell Pub.
- BMJ Books
- Date of Publication
- 2007
- Physical Description
- 82 p.
- Series Title
- ABC series
- ISBN
- 9781405136754
- Subjects (MeSH)
- Kidney Diseases
- Kidney Failure, Chronic
- Format
- Book
- Location
- Dickson Building
- Loan Period
- 3 weeks
Calcium and Phosphate Metabolism Management in Chronic Renal Disease
https://libcat.nshealth.ca/en/permalink/provcat30288
edited by Chen Hsing Hsu.
--Boston, MA:
Springer Science+Business Media
, c2006.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Hsu, Chen Hsing
- Responsibility
- edited by Chen Hsing Hsu
- Place of Publication
- Boston, MA
- Publisher
- Springer Science+Business Media
- Date of Publication
- c2006
- ISBN
- 9780387333700
- Subjects (MeSH)
- Calcium - metabolism
- Phosphates - metabolism
- Kidney Failure, Chronic - complications
- Kidney Failure, Chronic - metabolism
- Subjects (LCSH)
- Nephrology
- Format
- e-Book
- Location
- Online
Cardiorenal Syndrome : Mechanisms, Risk and Treatment
https://libcat.nshealth.ca/en/permalink/provcat29194
edited by Adel E. Berbari, Giuseppe Mancia.
--Milan:
Springer-Verlag
, c2010.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Berbari, Adel E
- Other Authors
- Mancia, Giuseppe
- Responsibility
- edited by Adel E. Berbari, Giuseppe Mancia
- Place of Publication
- Milan
- Publisher
- Springer-Verlag
- Date of Publication
- c2010
- ISBN
- 9788847014633
- Subjects (MeSH)
- Cardiovascular Diseases - complications
- Cardiovascular Diseases - physiopathology
- Kidney Failure, Chronic - complications
- Kidney Failure, Chronic - physiopathology
- Subjects (LCSH)
- Cardiology
- Nephrology
- Format
- e-Book
- Location
- Online
Chronic kidney disease, dialysis, and transplantation : a companion to Brenner and Rector’s The Kidney
https://libcat.nshealth.ca/en/permalink/provcat31616
[edited by] Jonathan Himmelfarb, T. Alp Ikizler.
(4th ed.)
--Philadelphia, PA:
Elsevier
, c2019.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
From basic science to practical clinical tools, Chronic Kidney Disease, Dialysis, and Transplantation, 4th Edition provides you with the up-to-date, authoritative guidance you need to safely and effectively manage patients with chronic renal disease. Covering all relevant clinical management issues, this companion volume to Brenner and Rector’s The Kidney presents the knowledge and expertise of renowned researchers and clinicians in the fields of hemodialysis, peritoneal dialysis, critical car…
- Available Online
- View e-Book
- Other Authors
- Himmelfarb, Jonathan
- Ikizler, T Alp
- Responsibility
- [edited by] Jonathan Himmelfarb, T. Alp Ikizler
- Edition
- 4th ed.
- Alternate Title
- Chronic kidney disease, dialysis, & transplantation
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- c2019
- Physical Description
- 1 online resource, 780 p.
- ISBN
- 9780323529785
- Subjects (MeSH)
- Renal Dialysis
- Kidney Failure, Chronic - complications
- Kidney Failure, Chronic - therapy
- Kidney Transplantation
- Subjects (LCSH)
- Hemodialysis
- Kidneys - Transplantation
- Renal Dialysis
- Kidney Failure, Chronic - complications
- Kidney Failure, Chronic - therapy
- Kidney Transplantation
- Specialty
- Nephrology
- Abstract
- From basic science to practical clinical tools, Chronic Kidney Disease, Dialysis, and Transplantation, 4th Edition provides you with the up-to-date, authoritative guidance you need to safely and effectively manage patients with chronic renal disease. Covering all relevant clinical management issues, this companion volume to Brenner and Rector’s The Kidney presents the knowledge and expertise of renowned researchers and clinicians in the fields of hemodialysis, peritoneal dialysis, critical care nephrology, and transplantation - for an all-in-one, indispensable guide to every aspect of this fast-changing field.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Chronic kidney disease, dialysis and transplantation : a companion to Brenner and Rector's the kidney
https://libcat.nshealth.ca/en/permalink/provcat21987
Pereira, Brian JG.
(2nd ed.)
--Philadelphia, PA:
Elsevier Saunders
, 2005.
- Call Number
- WJ 378 C557 2005 REF
- Location
- Dickson Building
- Sub-Location
- REFERENCE
- Call Number
- WJ 378 C557 2005 REF
- Author
- Pereira, Brian JG
- Other Authors
- Sayegh, Mohamed H
- Blake, Peter G
- Edition
- 2nd ed.
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier Saunders
- Date of Publication
- 2005
- Physical Description
- 889 p.
- ISBN
- 1416001581
- Subjects (MeSH)
- Kidney Failure, Chronic - therapy
- Renal Dialysis
- Kidney Transplantation
- Format
- Book
- Location
- Dickson Building
- Sub-Location
- REFERENCE
- Loan Period
- In library use
Chronic kidney disease, dialysis and transplantation : a companion to Brenner and Rector's The Kidney
https://libcat.nshealth.ca/en/permalink/provcat25747
Himmelfarb, Jonathan.
(3rd ed.)
Saunders Elsevier
, 2010.
- Call Number
- WJ 378 C557 2010
- Location
- Dickson Building
- Call Number
- WJ 378 C557 2010
- Author
- Himmelfarb, Jonathan
- Other Authors
- Sayegh, Mohamed H
- Edition
- 3rd ed.
- Publisher
- Saunders Elsevier
- Date of Publication
- 2010
- Physical Description
- 737 p.
- ISBN
- 9781437709872
- Subjects (MeSH)
- Kidney Failure, Chronic - therapy
- Kidney Transplantation
- Renal Dialysis
- Notes
- "Expert consult"--Cover.
- Format
- Book
- Location
- Dickson Building
- Copies
- 1
- Loan Period
- 3 weeks
Chronic kidney disease, dialysis, and transplantation : a companion to Brenner and Rector's the kidney
https://libcat.nshealth.ca/en/permalink/provcat50491
Himmelfarb, Jonathan.
(4th ed.)
--Philadelphia, PA:
Elsevier
, 2019.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Himmelfarb, Jonathan
- Edition
- 4th ed.
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- 2019
- ISBN
- 9780323529785
- Subjects (MeSH)
- Renal Dialysis
- Kidney Failure, Chronic - complications
- Kidney Failure, Chronic - therapy
- Kidney Transplantation
- Notes
- Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
- Format
- e-Book
- Location
- Online
Core Concepts in Dialysis and Continuous Therapies
https://libcat.nshealth.ca/en/permalink/provcat39690
Colm C. Magee, J. Kevin Tucker, Ajay K. Singh, editors.
--Boston, MA:
Springer US
, c2016.
- Available Online
- View e-Book
- Location
- Online
This clinically focused and authoritative guide to managing end stage renal disease (ESRD) patients provides the essentials of hemodialysis, peritoneal dialysis, and continuous therapies. Chapters cover the technical aspects of delivering dialysis therapy, clinical care of patients on dialysis and the evaluation and management of common complications of kidney failure in patients of dialysis - including anemia, bone disease and hypertension. Authored by worldwide leading experts in the field, t…
- Available Online
- View e-Book
- Other Authors
- Magee, Colm C
- Tucker, J. Kevin
- Singh, Ajay K
- Responsibility
- Colm C. Magee, J. Kevin Tucker, Ajay K. Singh, editors
- Place of Publication
- Boston, MA
- Publisher
- Springer US
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xi, 292 p. : 89 illus., 37 illus. in color)
- ISBN
- 9781489976574
- 9781489976550 (print ed.)
- Subjects (MeSH)
- Kidney Failure, Chronic - rehabilitation
- Renal Dialysis
- Abstract
- This clinically focused and authoritative guide to managing end stage renal disease (ESRD) patients provides the essentials of hemodialysis, peritoneal dialysis, and continuous therapies. Chapters cover the technical aspects of delivering dialysis therapy, clinical care of patients on dialysis and the evaluation and management of common complications of kidney failure in patients of dialysis - including anemia, bone disease and hypertension. Authored by worldwide leading experts in the field, this book is an invaluable resource for nephrologists and other healthcare professionals involved in dialysis treatment or caring for the ESRD patient.
- Contents
- Part I. Hemodialysis -- Epidemiology of End-Stage Renal Disease -- Technical Aspects of Hemodialysis -- Hemodialysis Dose -- Hemodialysis Complications -- Nutrition Management in Hemodialysis -- Vascular Access in Hemodialysis -- Managing Anemia and Metabolic Bone Disease in Dialysis Patients -- Part II. Home Therapies -- Technology of Peritoneal Dialysis -- Dosing of Peritoneal Dialysis -- Complications of Peritoneal Dialysis -- Peritoneal Dialysis in Children -- Special Problems in Caring for Patients on Peritoneal Dialysis -- Home Hemodialysis -- Wearable Dialysis Devices -- Part III. Continuous Therapies -- Continuous Renal Replacement Therapies (CRRT) Overview -- Continuous Renal Replacement Therapies Technology -- Complications of Continuous Renal Replacement Therapy (CRRT) -- Continuous Renal Replacement Therapy in Children -- Drug Dosing in Continuous Renal Replacement Therapy (CRRT) -- Part IV. Other Therapies -- Therapeutic Plasmapheresis -- High Cut-Off Hemodialysis -- Sorbents, Hemoperfusion Devices -- Hemodiafiltration.
- Format
- e-Book
- Location
- Online
Endocrine Disorders in Kidney Disease : Diagnosis and Treatment
https://libcat.nshealth.ca/en/permalink/provcat44255
Connie M. Rhee, Kamyar Kalantar-Zadeh, Gregory A. Brent, editors.
--Cham:
Springer
, 2019.
- Available Online
- View e-Book
- Location
- Online
This comprehensive book examines the complex interplay between endocrine and kidney disorders, and how this inter-relationship impacts patients with chronic kidney disease. Authored by experts in areas of endocrinology and nephrology, chapters cover a variety of topics, including diabetes, metabolic syndrome, thyroid dysfunction, gonadal disorders, dyslipidemia, mineral bone disorders, obesity, and pituitary disorders. These comorbidities are thoroughly examined and provide the clinician, resea…
- Available Online
- View e-Book
- Other Authors
- Rhee, Connie M.
- Kalantar-Zadeh, Kamyar
- Brent, Gregory A.
- Responsibility
- Connie M. Rhee, Kamyar Kalantar-Zadeh, Gregory A. Brent, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2019
- Physical Description
- 1 online resource (xiv, 354 p.) : 31 illus., 16 illus. in color
- ISBN
- 9783319977652
- 9783319977638 (Print ed.)
- 9783319977645 (Print ed.)
- Subjects (MeSH)
- Comorbidity
- Diabetic Nephropathies
- Endocrine System Diseases - complications
- Kidney Diseases - complications
- Kidney Failure, Chronic - complications
- Multiple Chronic Conditions
- Specialty
- Endocrinology
- Nephrology
- Abstract
- This comprehensive book examines the complex interplay between endocrine and kidney disorders, and how this inter-relationship impacts patients with chronic kidney disease. Authored by experts in areas of endocrinology and nephrology, chapters cover a variety of topics, including diabetes, metabolic syndrome, thyroid dysfunction, gonadal disorders, dyslipidemia, mineral bone disorders, obesity, and pituitary disorders. These comorbidities are thoroughly examined and provide the clinician, researcher, and trainee with a greater understanding of the impact of endocrine disorders on kidney disease patients, the ability to identify persistent gaps in knowledge for future investigation, and move closer towards the goal of improving the health and survival of the chronic kidney disease population.
- Contents
- Part I. Diabetes, Insulin Resistance, and the Metabolic Syndrome -- 1. Insulin Resistance and the Metabolic Syndrome in Kidney Disease (e.g. the Cardiorenal Metabolic Syndrome) -- 2. Diabetic Kidney Disease -- 3. Glucose Homeostasis and the Burnt-Out Diabetes Phenomenon in Patients with Kidney Disease -- 4. Glycemic Metrics and Targets in Kidney Disease -- 5. Diabetic Pharmacotherapies in Kidney Disease -- 6. Diabetes Mellitus and Renal Transplantation -- Part II. Thyroid Dysfunction -- 7. Evaluating Thyroid Function Tests in Patients with Kidney Disease -- 8. Thyroid Status and Outcomes in Kidney Disease -- Part III. Gonadal Disorders -- 9. Testosterone Deficiency and Other Testicular Disorders in Kidney Disease -- 10. Amenorrhea and Estrogen Disorders in Women with Kidney Disease -- 11. Pregnancy in Kidney Disease -- Part IV. Dyslipidemia -- 12. Lipid Disorders Associated with Chronic Kidney Disease and Nephrotic Syndrome -- 13. Drugs for Treatment of Dyslipidemia Available in the US -- Part V. Mineral Bone Disorders -- 14. Calcium Homeostasis in Kidney Disease -- 15. Phosphorus Retention and Elevated FGF-23 in Chronic Kidney Disease -- 16. Vitamin D and Parathyroid Hormone in Kidney Disease -- 17. Management of Bone Disorders in Kidney Disease -- 18. Mineral and Bone Disorders Following Renal Transplantation -- Part VI. Obesity and Adipokines -- 19. Obeesity in Kidney Disease -- 20. Adiponectin and Leptin in Kidney Disease Patients -- Part VII. Other Pituitary Disorders -- 21. Growth Hormone Disorders and Abnormal Stature in Kidney Disease -- 22. Other Pituitary Disorders and Kidney Disease -- 23. Endocrine System in Acute Kidney Injury -- 24. Nutrition and Endocrine Disorders in Kidney Disease.
- Format
- e-Book
- Location
- Online
Guidelines for nutrition care of renal patients
https://libcat.nshealth.ca/en/permalink/provcat20851
Wiggins, Kerri L.
(3rd ed.)
--Chicago, IL:
American Dietetic Association
, 2002.
- Call Number
- WJ 342 W655g 2002
- Location
- Dickson Building
- Call Number
- WJ 342 W655g 2002
- Author
- Wiggins, Kerri L
- Other Authors
- American Dietetic Association. Renal Practice Group
- Edition
- 3rd ed.
- Alternate Title
- Nutrition care of renal patients
- Place of Publication
- Chicago, IL
- Publisher
- American Dietetic Association
- Date of Publication
- 2002
- Physical Description
- 137 p.
- ISBN
- 0880911891
- Subjects (MeSH)
- Kidney Failure, Chronic - diet therapy
- Nutrition Assessment
- Format
- Book
- Location
- Dickson Building
- Loan Period
- 3 weeks
A healthy food guide for people on dialysis
https://libcat.nshealth.ca/en/permalink/provcat20838
American Dietetic Association. Renal Practice Group.
(2nd ed.)
--Chicago, IL:
American Dietetic Association
, 2002.
- Call Number
- WJ 300 H435 2002
- Location
- Dickson Building
- Call Number
- WJ 300 H435 2002
- Corporate Author
- American Dietetic Association. Renal Practice Group
- Other Authors
- Harvey, Kathy Schiro
- Edition
- 2nd ed.
- Alternate Title
- National renal diet
- Place of Publication
- Chicago, IL
- Publisher
- American Dietetic Association
- Date of Publication
- 2002
- Physical Description
- 42 p.
- ISBN
- 876502169X
- Subjects (MeSH)
- Kidney Failure, Chronic - diet therapy
- Renal Dialysis
- Notes
- "National Renal diet"--t.p.
- Format
- Book
- Location
- Dickson Building
- Copies
- 2
- Loan Period
- 3 weeks
A healthy food guide for people with chronic kidney disease
https://libcat.nshealth.ca/en/permalink/provcat20817
American Dietetic Association. Renal Practice Group.
(2nd ed.)
--Chicago, IL:
American Dietetic Association
, 2002.
- Call Number
- WJ 300 H434 2002
- Location
- Dickson Building
- Call Number
- WJ 300 H434 2002
- Corporate Author
- American Dietetic Association. Renal Practice Group
- Other Authors
- Harvey, Kathy Schiro
- Edition
- 2nd ed.
- Alternate Title
- National renal diet
- Place of Publication
- Chicago, IL
- Publisher
- American Dietetic Association
- Date of Publication
- 2002
- Physical Description
- 32 p.
- ISBN
- 0880914017
- Notes
- "National Renal diet"--t.p.
- Format
- Book
- Publication Type
- Popular Works
- Location
- Dickson Building
- Loan Period
- 3 weeks
Kidney transplantation : principles and practice
https://libcat.nshealth.ca/en/permalink/provcat32690
Stuart J. Knechtle, Lorna P. Marson, Peter J. Morris.
(8th ed.)
--Philadelphia, PA:
Elsevier
, c2020.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
Offering practical guidance for all members of the transplant team, Kidney Transplantation, Principles and Practice, 8th Edition, provides the balanced, up-to-date information you need to achieve optimal outcomes for your patients. A global team of internationally renowned surgeons and nephrologists, many new to this edition, offers fresh perspectives on everything from applied science and surgical techniques to immunosuppressive methods, outcomes, risks, and medical considerations related to …
- Available Online
- View e-Book
- Author
- Morris, Peter J
- Other Authors
- Knechtle, Stuart J
- Responsibility
- Stuart J. Knechtle, Lorna P. Marson, Peter J. Morris
- Edition
- 8th ed.
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- c2020
- Physical Description
- 1 online resource, 752 p.
- ISBN
- 9780323531863
- Subjects (MeSH)
- Kidney Transplantation
- Renal Insufficiency - surgery
- Kidney Failure, Chronic - surgery
- Specialty
- Nephrology
- Transplantation
- Abstract
- Offering practical guidance for all members of the transplant team, Kidney Transplantation, Principles and Practice, 8th Edition, provides the balanced, up-to-date information you need to achieve optimal outcomes for your patients. A global team of internationally renowned surgeons and nephrologists, many new to this edition, offers fresh perspectives on everything from applied science and surgical techniques to immunosuppressive methods, outcomes, risks, and medical considerations related to kidney transplantation, in both adults and children.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Manual of Clinical Dialysis
https://libcat.nshealth.ca/en/permalink/provcat30054
by Suhail Ahmad.
(2nd ed.)
--Boston, MA:
Springer-Verlag US
, c2009.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Ahmad, Suhail
- Responsibility
- by Suhail Ahmad
- Edition
- 2nd ed.
- Place of Publication
- Boston, MA
- Publisher
- Springer-Verlag US
- Date of Publication
- c2009
- ISBN
- 9780387096513
- Subjects (MeSH)
- Kidney Failure, Chronic - therapy
- Peritoneal Dialysis - methods
- Renal Dialysis - methods
- Subjects (LCSH)
- Nephrology
- Format
- e-Book
- Location
- Online
Principles and practice of dialysis
https://libcat.nshealth.ca/en/permalink/provcat21495
Henrich, William L.
(3rd ed.)
--Philadelphia, PA:
Lippincott Williams & Wilkins
, 2004.
- Call Number
- WJ 378 P957 2004
- Location
- Dickson Building
- Call Number
- WJ 378 P957 2004
- Author
- Henrich, William L
- Edition
- 3rd ed.
- Place of Publication
- Philadelphia, PA
- Publisher
- Lippincott Williams & Wilkins
- Date of Publication
- 2004
- Physical Description
- 696 p.
- ISBN
- 0781738814
- Subjects (MeSH)
- Renal Dialysis
- Kidney Failure, Chronic - therapy
- Kidney Failure, Chronic - complications
- Format
- Book
- Location
- Dickson Building
- Loan Period
- 3 weeks
Recent Advances of Sarcopenia and Frailty in CKD
https://libcat.nshealth.ca/en/permalink/provcat45284
Akihiko Kato, Eiichiro Kanda, Yoshihiko Kanno, editors.
--Singapore:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book highlights recent advances in our understanding of sarcopenia and frailty in CKD. The prevalence of sarcopenia and frailty increases substantially as CKD progresses, and experimental studies have demonstrated the pivotal role of accumulated uremic toxin in the development of muscle wasting. Further, sarcopenia and frailty are associated with falls, bone fractures, cognitive impairment, and poor survival prognoses, especially in elderly CKD patients. The syndromes are also related to t…
- Available Online
- View e-Book
- Other Authors
- Kato, Akihiko
- Kanda, Eiichiro
- Kanno, Yoshihiko
- Responsibility
- Akihiko Kato, Eiichiro Kanda, Yoshihiko Kanno, editors
- Alternate Title
- Recent advances of sarcopenia and frailty in chronic kidney disease
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (viii, 245 p.) : 55 illus., 25 illus. in color
- ISBN
- 9789811523656
- 9789811523649 (Print ed.)
- 9789811523663 (Print ed.)
- 9789811523670 (Print ed.)
- Subjects (MeSH)
- Frail Elderly
- Frailty - prevention & control
- Kidney Failure, Chronic - complications
- Sarcopenia - prevention & control
- Specialty
- Geriatrics
- Nephrology
- Abstract
- This book highlights recent advances in our understanding of sarcopenia and frailty in CKD. The prevalence of sarcopenia and frailty increases substantially as CKD progresses, and experimental studies have demonstrated the pivotal role of accumulated uremic toxin in the development of muscle wasting. Further, sarcopenia and frailty are associated with falls, bone fractures, cognitive impairment, and poor survival prognoses, especially in elderly CKD patients. The syndromes are also related to the risk of end-stage kidney disease. This book provides readers with a deeper understanding of the prevention and management of sarcopenia and frailty in CKD patients to improve their renal and overall health, and suggests directions for future basic and clinical research.
- Contents
- 1. Epidemiology of sarcopenia and frailty in CKD -- 2. Molecular mechanism of muscle wasting in CKD -- 3. Protein Energy Wasting in Chronic Kidney Disease -- 4. Benefit and risk of exercise training in CKD patients -- 5. Frailty in patients with pre-dialysis CKD: toward successful aging of the elderly patients transitioning to dialysis in Japan -- 6. Exercise interventions in dialysis patients -- 7. Exercise intervention for kidney transplant recipients: recent progress and remaining issues -- 8. Role of nutrition and rehabilitation in the prevention and management of sarcopenia and frailty -- 9. Nutritional interventions in elderly pre-dialysis patients -- 10. Nutritional interventions in dialysis patients -- 11. Pharmacological intervention for sarcopenia in CKD -- 12. Oral Health Management for the Prevention of Sarcopenia and Frailty -- 13. Frailty and cognitive impairment in CKD -- 14. Polypharmacy and frailty in CKD -- 15. Anemia management and QOL and frailty in CKD.
- Format
- e-Book
- Location
- Online
Uremic Toxins and Organ Failure
https://libcat.nshealth.ca/en/permalink/provcat46096
Hideyuki Saito, Takaaki Abe, editors.
--Singapore:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book describes the latest research on the gut-kidney axis of ureic solutes; the toxico-pathological mechanisms of uremic toxin-induced organ failure, including kidney and cardiovascular tissue; and the preventive therapeutic strategies for uremia and related organ failure associated with kidney injuries and diseases. Retained uremic toxins cause a variety of symptoms, such as hypertension, fatigue, renal anemia, osteoporosis and neurologic impairment, which are apparent in chronic kidney d…
- Available Online
- View e-Book
- Other Authors
- Saito, Hideyuki
- Abe, Takaaki
- Responsibility
- Hideyuki Saito, Takaaki Abe, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (viii, 180 p.) : 39 illus., 22 illus. in color
- ISBN
- 9789811577932
- 9789811577925 (Print ed.)
- 9789811577949 (Print ed.)
- 9789811577956 (Print ed.)
- Subjects (MeSH)
- Kidney Failure, Chronic - complications
- Multiple Organ Failure - physiopathology
- Toxins, Biological - metabolism
- Uremia - metabolism
- Specialty
- Biochemistry
- Toxicology
- Abstract
- This book describes the latest research on the gut-kidney axis of ureic solutes; the toxico-pathological mechanisms of uremic toxin-induced organ failure, including kidney and cardiovascular tissue; and the preventive therapeutic strategies for uremia and related organ failure associated with kidney injuries and diseases. Retained uremic toxins cause a variety of symptoms, such as hypertension, fatigue, renal anemia, osteoporosis and neurologic impairment, which are apparent in chronic kidney disease (CKD) patients. The human gastrointestinal tract contains trillions of microorganisms, referred to as gut microbiota, which support the host metabolism by producing nutrients, such as vitamins and short-chain fatty acids. However, they also produce various harmful uremic toxins that show renal and cardiovascular toxicity, and correlate with an increased mortality in CKD patients. The composition and balance of gut microbiota are associated with the accumulation of uremic toxins and the pathophysiology of CKD, and as such are being considered for a novel therapeutic strategy.
- Contents
- 1. Overview of Uremic Toxins -- 2. Review: Uremic toxins and gut microbiome -- 3. Gut microbiota and systemic uremic solute accumulation -- 4. Uremic toxin-related systemic disorders -- 5. Uremic toxins and cardiovascular disease -- 6. Indoxyl sulfate and arteriosclerosis -- 7. Uremic toxicity and bone in CKD -- 8. D-serine as a novel uremic toxin -- 9. Uremic solutes and sarcopenia -- 10. Toxico-pathological role of hepatic sulfotransferase (SULT) 1A1 in acute kidney injuries -- 11. Accumulation of uremic toxins in systemic organs and the effect of AST-120.
- Format
- e-Book
- Location
- Online
