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An Information Technology Framework for Predictive, Preventive and Personalised Medicine : A Use-Case with Hepatocellular Carcinoma

https://libcat.nshealth.ca/en/permalink/provcat39137
Leonard Berliner, Heinz U. Lemke, editors. --Cham: Springer , c2015.
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This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact tha…
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Other Authors
Berliner, Leonard
Lemke, Heinz U
Responsibility
Leonard Berliner, Heinz U. Lemke, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xx, 130 p. : 23 illus., 15 illus. in color)
Series Vol.
v. 8
Series Title
Advances in predictive, preventive and personalised medicine
ISBN
9783319121666
9783319121659 (print ed.)
ISSN
2211-3495
Subjects (MeSH)
Carcinoma, Hepatocellular - therapy
Medical Informatics - methods
Precision Medicine - methods
Preventive Medicine - methods
Abstract
This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.
Contents
Preface -- Introduction -- The Digital Patient Model and Model Guided Therapy -- Hepatocellular Carcinoma and Patient Assessment -- Imaging in Hepatocellular Carcinoma: Radiologic Assessment -- Imaging in Hepatocellular Carcinoma: PET/CT -- Personalized Chemotherapy for Hepatocellular Carcinoma -- Surgical Treatment for Hepatocellular Carcinoma -- Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Technologies -- Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Therapies -- Minimally Invasive Therapies for Hepatocellular Cancer: Catheter-Directed Therapies -- Radiation Oncology in the Treatment of Hepatocellular Carcinoma -- Design of an IT System for Hepatocellular Carcinoma -- Outlook and Expert Recommendations for Predictive, Preventive and Personalized Medicine and Hepatocellular Carcinoma.
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e-Book
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Biomedical Informatics for Cancer Research

https://libcat.nshealth.ca/en/permalink/provcat28720
edited by Michael F. Ochs, John T. Casagrande, Ramana V. Davuluri. --Boston, MA: Springer Science+Business Media , c2010.
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Author
Ochs, Michael F
Other Authors
Casagrande, John T
Davuluri, Ramana V
Responsibility
edited by Michael F. Ochs, John T. Casagrande, Ramana V. Davuluri
Place of Publication
Boston, MA
Publisher
Springer Science+Business Media
Date of Publication
c2010
ISBN
9781441957146
Subjects (MeSH)
Biomedical Research - methods
Computational Biology - methods
Medical Informatics - methods
Medical Oncology
Subjects (LCSH)
Oncology
Medical records - Data processing
Bioinformatics
Format
e-Book
Location
Online
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Data and Text Processing for Health and Life Sciences

https://libcat.nshealth.ca/en/permalink/provcat43941
Francisco M. Couto. --Cham: SpringerOpen , c2019.
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Open access
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Online
This open access book is a step-by-step introduction on how shell scripting can help solve many of the data processing tasks that Health and Life specialists face everyday with minimal software dependencies. The examples presented in the book show how simple command line tools can be used and combined to retrieve data and text from web resources, to filter and mine literature, and to explore the semantics encoded in biomedical ontologies. To store data this book relies on open standard text fil…
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Author
Couto, Francisco M.
Responsibility
Francisco M. Couto
Place of Publication
Cham
Publisher
SpringerOpen
Date of Publication
c2019
Physical Description
1 online resource (xv, 98 p.) : 483 illus., 74 illus. in color.
Series Vol.
v. 1137
Series Title
Advances in experimental medicine and biology
ISBN
9783030138455
9783030138448 (Print ed.)
9783030138462 (Print ed.)
ISSN
0065-2598
Subjects (MeSH)
Biomedical Research - methods
Data Mining
Electronic Data Processing
Medical Informatics - methods
Specialty
Medical Informatics
Abstract
This open access book is a step-by-step introduction on how shell scripting can help solve many of the data processing tasks that Health and Life specialists face everyday with minimal software dependencies. The examples presented in the book show how simple command line tools can be used and combined to retrieve data and text from web resources, to filter and mine literature, and to explore the semantics encoded in biomedical ontologies. To store data this book relies on open standard text file formats, such as TSV, CSV, XML, and OWL, that can be open by any text editor or spreadsheet application. The first two chapters, Introduction and Resources, provide a brief introduction to the shell scripting and describe popular data resources in Health and Life Sciences. The third chapter, Data Retrieval, starts by introducing a common data processing task that involves multiple data resources. Then, this chapter explains how to automate each step of that task by introducing the required commands line tools one by one. The fourth chapter, Text Processing, shows how to filter and analyze text by using simple string matching techniques and regular expressions. The last chapter, Semantic Processing, shows how XPath queries and shell scripting is able to process complex data, such as the graphs used to specify ontologies. Besides being almost immutable for more than four decades and being available in most of our personal computers, shell scripting is relatively easy to learn by Health and Life specialists as a sequence of independent commands. Comprehending them is like conducting a new laboratory protocol by testing and understanding its procedural steps and variables, and combining their intermediate results. Thus, this book is particularly relevant to Health and Life specialists or students that want to easily learn how to process data and text, and which in return may facilitate and inspire them to acquire deeper bioinformatics skills in the future.
Contents
Introduction -- Resources -- Data Retrieval -- Text Processing -- Semantic Processing.
Access
Open access
Format
e-Book
Location
Online
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Healthcare Information Management Systems : Cases, Strategies, and Solutions

https://libcat.nshealth.ca/en/permalink/provcat39829
Charlotte A. Weaver, Marion J. Ball, George R. Kim, Joan M. Kiel, editors. (Fourth edition) --Cham: Springer , c2016.
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This book provides a bold and honest description of the current state of electronic health record (EHR) technologies in acute and primary care settings, and looks at the future through the lens of emerging new technologies, changes in care delivery models and reimbursement policies. This 4th Edition of Healthcare Information Management Systems: Cases, Strategies, and Solutions has been thoroughly updated, as concepts such as Meaningful Use (MU), interoperability, personalized medicine and healt…
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Other Authors
Weaver, Charlotte A
Ball, Marion J
Kim, George R
Kiel, Joan M
Responsibility
Charlotte A. Weaver, Marion J. Ball, George R. Kim, Joan M. Kiel, editors
Edition
Fourth edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xxiii, 618 p. : 65 illus., 57 illus. in color)
Series Title
Health informatics
ISBN
9783319207650
9783319207643 (print ed.)
ISSN
1431-1917
Subjects (MeSH)
Electronic Health Records
Health Facility Administration
Management Information Systems
Medical Informatics - methods
Abstract
This book provides a bold and honest description of the current state of electronic health record (EHR) technologies in acute and primary care settings, and looks at the future through the lens of emerging new technologies, changes in care delivery models and reimbursement policies. This 4th Edition of Healthcare Information Management Systems: Cases, Strategies, and Solutions has been thoroughly updated, as concepts such as Meaningful Use (MU), interoperability, personalized medicine and health IT have had a considerable impact on patient safety and health outcomes. It outlines the issues of EHR adoption under MU and, as anticipated gains in efficiency, quality and costs have not always been seen, it also provides a framework within which solutions to the frustration, dissatisfaction, and growing concerns can be found. Many suggest that a technology sea change is needed with a second generation of EHRs developed on 21st century architectures that more closely match the flexibility and power of mobile and web-based applications available in the general marketplace. Building on the success of its previous three editions, this book will guide healthcare professionals as they confront the technical, organizational, and management issues related to the selection, implementation, and management of healthcare information systems. It will contribute to taking us into a healthcare system that delivers value, is a pleasure to work within, and relieves the taxpayers' burden.
Contents
Part I. The Current State of Health Information Management in the United States -- Clinical Decision Support: History and Basic Concepts -- Electronic Health Record Features, Functions, and Privileges that Clinicians Need to Provide Safe and Effective Care for Adults and Children -- The Journey To Usablity: A Vendor's Perspective -- Snapshot at mid-stride: Current state of EHRs and their use by clinicians from a CMIO's perspective -- The Evolution of EHR-S Functionality for Care and Coordination -- Great Promises of Healthcare Information Technology Deliver Less -- Ten Reasons Why Interoperability is Difficult -- The Evolution of Health Information Technology Policy in the United States -- Part II. The Evolving State of Health IT: Reinventing Care, Roles and Connections -- Usability: Making it Real from Concepts to Implementation and End-User Adoption -- Incorporating Patient Generated Health Data into Chronic Disease Management: A Human Factors Approach -- Transformed Roles for a Transformed Healthcare System: Where Do Clinical Informaticists Fit in Now? -- Emerging Roles in Health and Healthcare -- Impact of the Digital Age on Transforming Healthcare -- Health Information Crossroad: An opportunity to deliver real measurable outcomes for better health and well being -- Health IT's Essential Role in the Patient-Centered Medical Home and Practice-Based Population Health Management -- Patient-Interactive Healthcare Management, a Model for Achieving Patient Experience Excellence -- The Patient of the Future: Participatory Medicine & Enabling Technologies -- Part III. Looking Forward: Near Future Initiatives to Make Things Better -- Data Driven Patient Safety and Clinical Information Technology -- Simulation: A View Into The Future Of Education -- The Health Record Banking Model for Health Information Infrastructure -- Next Generation Wellness: A Technology Model for Personalizing Healthcare -- Wearable Technologies and Telehealth in Care Management for Chronic Illness -- The Role of Big Data and Analytics in Health Payer Transformation to Consumer-Centricity -- Interoperability: E Pluribus Unum -- Privacy & Data Security: HIPAA & HITECH -- Part IV. Looking Towards the Year 2025 -- Building a Reliable and Affordable System of Medical Care -- Engineering the Next Generation of Health Systems -- Emerging Clinical Decision Support Technology for the 21st Century -- Beyond Current HIMS: Future Visions and a Roadmap Big Data Analytical Technologies and Decision Support in Critical Care -- Data Driven Analytics for Personalized Healthcare -- Cognitive Computing for Electronic Medical Records -- Health Information Systems 2025.
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e-Book
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Health Informatics : Translating Information into Innovation

https://libcat.nshealth.ca/en/permalink/provcat46349
Hironobu Matsushita, editor. --Singapore: Springer , c2021.
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NEW Springer 2021
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This book is the first to approach healthcare informatics from the perspective of innovation. Drawing on the unique pairing of information and innovation, it offers an analysis to help readers rethink information technology, knowledge management, interprofessional collaboration and the generation of wisdom in the context of healthcare. The concept of “translational” research stems from the medical and health sciences, and features bidirectional and recursive information-generation processes inv…
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Other Authors
Matsushita, Hironobu
Responsibility
Hironobu Matsushita, editor
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2021
Physical Description
1 online resource (xiv, 174 p.) : 57 illus., 39 illus. in color
Series Vol.
24
Series Title
Translational systems sciences
ISBN
9789811537813
9789811537806 (Print ed.)
9789811537820 (Print ed.)
9789811537837 (Print ed.)
ISSN
2197-8832
Subjects (MeSH)
Medical Informatics - methods
Medical Informatics Applications
Specialty
Medical Informatics
Abstract
This book is the first to approach healthcare informatics from the perspective of innovation. Drawing on the unique pairing of information and innovation, it offers an analysis to help readers rethink information technology, knowledge management, interprofessional collaboration and the generation of wisdom in the context of healthcare. The concept of “translational” research stems from the medical and health sciences, and features bidirectional and recursive information-generation processes involving bed-to-bench and bench-to-bed approaches. Based partly on this, translational systems science has become a new trend within systems sciences, motivated by the need for practical applications that help people by offering holistic systems solutions for complex ideas. Today, numerous innovations are emerging in diversified clinical practices, and there has been a remarkable convergence of new technologies in disciplines like genome therapy, immunotherapy, iPS cells, imaging diagnosis, personalized medicine, molecular targeted drugs, surgical robots, and remote nursing. Innovation is also occurring in health management fields, including health records, insurance reimbursement methods, quality control, and safety. In these areas, big data and machine learning are accelerating innovation. Behind these innovations are the creation, sharing, bridging, and translation of data, information, knowledge, and wisdom, and as such health informatics is critical in promoting health innovations. The book explores the horizons of health informatics, introducing cutting-edge practical cases and theoretical frameworks, including but not limited to fields such as big data, machine learning, drug discovery, interprofessional collaboration, electronic health records, robotics, telenursing, quality improvement, and safety.
Contents
Innovation in Health Informatics -- Innovation of Community-Based Integrated Care: The History and Current Status of Telenursing in Japan -- Information Technology/Artificial Intelligence Innovations Needed for Better Quality of Life in Caregiving Homes -- A New Informatics: Trajectory Patterns in Health Indexes for Japanese Elders and Systemic Change to Life Course Approach -- Real-World Data-Based Care Innovation: Lessons Learned from Nursing Science -- Health Informatics and Co-Innovation: Connecting Patients, Clinical Practice, and Technology -- Translating Evidence into Practice: An Experience with Interprofessional Education (IPE) -- Realities and Challenges of Bridging Research in Japan -- Current Status and Issues with Japan’s Community-Based Integrated Care System: Health Information System and Health Information Exchange System Framework.
Access
NEW Springer 2021
Format
e-Book
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Online
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Infectious Disease Informatics and Biosurveillance : Research, Systems and Case Studies

https://libcat.nshealth.ca/en/permalink/provcat40893
editors, Daniel Zeng, Hsinchun Chen, Carlos Castillo-Chavez, William B. Lober, Mark Thurmond. --New York, NY: Springer , c2011.
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This book on Infectious Disease Informatics (IDI) and biosurveillance is intended to provide an integrated view of the current state of the art, identify technical and policy challenges and opportunities, and promote cross-disciplinary research that takes advantage of novel methodology and what we have learned from innovative applications. This book also fills a systemic gap in the literature by emphasizing informatics driven perspectives (e.g., information system design, data standards, comput…
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Other Authors
Zeng, Daniel
Chen, Hsinchun
Castillo-Chavez, Carlos
Lober, William B
Thurmond, Mark
Responsibility
editors, Daniel Zeng, Hsinchun Chen, Carlos Castillo-Chavez, William B. Lober, Mark Thurmond
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2011
Physical Description
1 online resource (li, 488 p. : ill.)
Series Vol.
27
Series Title
Integrated Series in Information Systems
ISBN
9781441968920
9781441968913 (print ed.)
ISSN
1571-0270
Subjects (MeSH)
Biosurveillance
Communicable Disease Control - methods
Epidemiological Monitoring
Medical Informatics - methods
Abstract
This book on Infectious Disease Informatics (IDI) and biosurveillance is intended to provide an integrated view of the current state of the art, identify technical and policy challenges and opportunities, and promote cross-disciplinary research that takes advantage of novel methodology and what we have learned from innovative applications. This book also fills a systemic gap in the literature by emphasizing informatics driven perspectives (e.g., information system design, data standards, computational aspects of biosurveillance algorithms, and system evaluation). Finally, this book attempts to reach policy makers and practitioners through the clear and effective communication of recent research findings in the context of case studies in IDI and biosurveillance, providing "hands-on" in-depth opportunities to practitioners to increase their understanding of value, applicability, and limitations of technical solutions. This book collects the state of the art research and modern perspectives of distinguished individuals and research groups on cutting-edge IDI technical and policy research and its application in biosurveillance. The contributed chapters are grouped into three units. Unit I provides an overview of recent biosurveillance research while highlighting the relevant legal and policy structures in the context of IDI and biosurveillance ongoing activities. It also identifies IDI data sources while addressing information collection, sharing, and dissemination issues as well as ethical considerations. Unit II contains survey chapters on the types of surveillance methods used to analyze IDI data in the context of public health and bioterrorism. Specific computational techniques covered include: text mining, time series analysis, multiple data streams methods, ensembles of surveillance methods, spatial analysis and visualization, social network analysis, and agent-based simulation. Unit III examines IT and decision support for public health event response and bio-defense. Practical lessons learned in developing public health and biosurveillance systems, technology adoption, and syndromic surveillance for large events are discussed. The goal of this book is to provide an understandable interdisciplinary IDI and biosurveillance reference either used as a standalone textbook or reference for students, researchers, and practitioners in public health, veterinary medicine, biostatistics, information systems, computer science, and public administration and policy. Integrated Series in Information Systems (IS2) strives to publish scholarly work in the technical as well as the organizational side of the field. This series contains three sub-series including: expository and research monographs, integrative handbooks, and edited volumes, focusing on the state-of-the-art of application domains and/or reference disciplines, as related to information systems.
Contents
1. Real-Time Public Health Biosurveillance: Systems and Policy Considerations -- 2. Designing Ethical Pratice in Biosurveillance: The Project Argus Doctrine -- 3. Using Emergency Department Data for Biosurveillance: The North Carolina Experience -- 4. Clinical Laboratory Data for Biosurveillance -- 5. Biosurveillance Based on Test Orders from Veterinary Diagnostic Labs -- 6. Markov Switching Models for Outbreak Detection -- 7. Detection of Events in Multiple Streams of Surveillance Data: Multivariate, Multi-stream and Multidimensional Approaches -- 8. Algorithm Combination for Improved Performance in Biosurveillance: Algorithms Combination for Improved Surveillance -- 9. Modeling in Space and Time: A Framework for Visualization and Collaboration -- 10. Surveillance of Infectious Diseases Using Spatial and Temporal Clustering Methods: Spatial and Temporal Clustering Methods Used in Epidemiology of Infectious Diseases -- 11. Age-Adjustment in National Biosurveillance Systems: A Survey of Issues and Analytical Tools for Age-adjustment in Biosurveillance -- 12. Modeling in Immunization and Biosurveillance -- 13. Natural Language Processing for Biosurveillance: Detection and Characterization from Textual Clinical Reports -- 14. Knowledge Mapping for Bioterrorism-related Literature -- 15. Social Networking Analysis for Contract Tracing -- 16. Multi-Agent Modeling of Biological and Chemical Threats -- 17. Integrated Health Altering and Notification: A Case Study in New York State -- 18. Design and Performance of a Public Health Preparedness Informatics Framework -- 19. System Evaluation and User Technology Adoption: A Case Study of BioPortal -- 20. Syndromic Surveillance for the G8 Hokkaido Toyako Summit Meeting.
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e-Book
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Online
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Infectious Disease Informatics : Syndromic Surveillance for Public Health and BioDefense

https://libcat.nshealth.ca/en/permalink/provcat40921
Hsinchun Chen, Daniel Zeng, Ping Yan. --New York, NY: Springer , c2010.
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Computer-based infectious disease surveillance systems are capable of real-time or near real-time detection of serious illnesses and potential bioterrorism agent exposures and represent a major step forward in disease surveillance. Infectious Disease Informatics: Syndromic Surveillance for Public Health and Bio-Defense is an in-depth monograph that analyzes and evaluates the outbreak modeling and detection capabilities of existing surveillance systems under a unified framework, and presents the…
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Author
Chen, Hsinchun
Other Authors
Zeng, Daniel
Yan, Ping
Responsibility
Hsinchun Chen, Daniel Zeng, Ping Yan
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2010
Physical Description
1 online resource (xxiv, 210 p. : 68 illus.)
Series Vol.
21
Series Title
Integrated Series in Information Systems
ISBN
9781441912787
9781441912770 (print ed.)
ISSN
1571-0270
Subjects (MeSH)
Medical Informatics - methods
Communicable Diseases - epidemiology
Population Surveillance - methods
Abstract
Computer-based infectious disease surveillance systems are capable of real-time or near real-time detection of serious illnesses and potential bioterrorism agent exposures and represent a major step forward in disease surveillance. Infectious Disease Informatics: Syndromic Surveillance for Public Health and Bio-Defense is an in-depth monograph that analyzes and evaluates the outbreak modeling and detection capabilities of existing surveillance systems under a unified framework, and presents the first book-length coverage of the subject from an informatics-driven perspective. Individual chapters consider the state of the art, including the facilitation of data collection, sharing and transmission; a focus on various outbreak detection methods; data visualization and information dissemination issues; and system assessment and other policy issues. Eight chapters then report on several real-world case studies, summarizing and comparing eight syndromic surveillance systems, including those that have been adopted by many public health agencies (e.g., RODS and BioSense). The book concludes with a discussion of critical issues and challenges, with a look to future directions. This book is an excellent source of current information for researchers in public health and IT. Government public health officials and private-sector practitioners in both public health and IT will find the most up-to-date information available, and students from a variety of disciplines, including public health, biostatistics, information systems, computer science, and public administration and policy will get a comprehensive look at the concepts, techniques, and practices of syndromic surveillance.
Contents
Part I. SYNDROMIC SURVEILLANCE SYSTEMS -- Infectious Disease Informatics: An Introduction and An Analysis Framework -- Public Health Syndromic Surveillance Systems -- Syndromic Surveillance Data Sources and Collection Strategies -- Data Analysis and Outbreak Detection -- Data Visualization, Information Dissemination, and Alerting -- System Assessment and Evaluation -- Part II. SYNDROMIC SURVEILLANCE SYSTEM CASE STUDIES -- BioSense -- RODS -- BioPortal -- ESSENCE -- New York City Syndromic Surveillance Systems -- EARS -- Argus -- HealthMap -- Challenges and Future Directions.
Format
e-Book
Location
Online
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Pediatric Informatics : Computer Applications in Child Health

https://libcat.nshealth.ca/en/permalink/provcat30332
edited by Christoph U. Lehmann, George R. Kim, Kevin B. Johnson. --New York, NY: Springer , c2009.
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Online
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Author
Lehmann, Christoph U
Other Authors
Kim, George R
Johnson, Kevin B
Responsibility
edited by Christoph U. Lehmann, George R. Kim, Kevin B. Johnson
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2009
Series Title
Health informatics
ISBN
9780387764467
Subjects (MeSH)
Pediatrics
Medical Informatics - methods
Subjects (LCSH)
Telecommunication in medicine
Pediatrics
Format
e-Book
Location
Online
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Practical Pathology Informatics : Demstifying informatics for the practicing anatomic pathologist

https://libcat.nshealth.ca/en/permalink/provcat29965
by John H. Sinard. --New York, NY: Springer Science+Business Media , c2006.
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Online
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Author
Sinard, John H
Responsibility
by John H. Sinard
Place of Publication
New York, NY
Publisher
Springer Science+Business Media
Date of Publication
c2006
ISBN
9780387280585
Subjects (MeSH)
Medical Informatics - methods
Pathology - methods
Subjects (LCSH)
Medical records - Data processing
Pathology
Format
e-Book
Location
Online
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Project Management for Healthcare Informatics

https://libcat.nshealth.ca/en/permalink/provcat29576
by Susan M. Houston, Lisa Anne Bove. --New York, NY: Springer Science+Business Media , c2007.
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Online
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Author
Houston, Susan M
Other Authors
Bove, Lisa Anne
Responsibility
by Susan M. Houston, Lisa Anne Bove
Place of Publication
New York, NY
Publisher
Springer Science+Business Media
Date of Publication
c2007
Series Title
Health informatics
ISBN
9780387736839
Subjects (MeSH)
Health Planning
Health Services Administration
Medical Informatics - methods
Program Development
Subjects (LCSH)
Project management
Telecommunication in medicine
Format
e-Book
Location
Online
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Translational Informatics : Realizing the Promise of Knowledge-Driven Healthcare

https://libcat.nshealth.ca/en/permalink/provcat38879
Philip R.O. Payne, Peter J. Embi, editors. --London: Springer , c2015.
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Emergent and multidisciplinary research paradigms have fundamentally transformed biomedical science and the delivery of clinical care. A common theme spanning such transformative changes is the use of rigorous and systematic approaches to the collection, management, integration, analysis, and dissemination of data. Unfortunately, the absence of well-established theoretical and practical frameworks intended to address such needs remains a major impediment to the realization of a translational an…
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Other Authors
Payne, Philip R.O.
Embi, Peter J
Responsibility
Philip R.O. Payne, Peter J. Embi, editors
Place of Publication
London
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (ix, 185 p. : 34 illus., 27 illus. in color)
Series Title
Health informatics
ISBN
9781447146469
9781447146452 (print ed.)
ISSN
1431-1917
Subjects (MeSH)
Medical Informatics - methods
Abstract
Emergent and multidisciplinary research paradigms have fundamentally transformed biomedical science and the delivery of clinical care. A common theme spanning such transformative changes is the use of rigorous and systematic approaches to the collection, management, integration, analysis, and dissemination of data. Unfortunately, the absence of well-established theoretical and practical frameworks intended to address such needs remains a major impediment to the realization of a translational and knowledge-driven healthcare system. This book provides practical advice on the integrative and translational methodologies and frameworks that have transformed modern biomedical research Translational Informatics presents a broad framework and specific examples of how the deep integration of biomedical informatics with both biomedical research and clinical care delivery is essential to overcoming such barriers and achieving the benefits of a knowledge-based approach to the delivery of high-performance, quality, safe, and individually tailored healthcare. It will be of great value to a wide range of professionals involved in the discipline, as it: Defines the challenges and opportunities surrounding translational medicine, with a focus on the data, information, and knowledge needed to achieve such a healthcare model Introduces readers to core biomedical informatics theories and methods underlying the translational medicine paradigm Discusses future directions for the field of translational medicine.
Contents
Part I. The rationale for translational informatics -- An introduction to translational informatics and the future of knowledge-driven healthcare -- A prototype of translational informatics in action -- Part II. Foundations of translational informatics -- Personalized medicine -- Leveraging electronic health records for phenotyping -- Mining the bibliome -- Part III. Applications of translational informatics -- Driving clinical and translational research using biomedical informatics -- Using big data -- In silico hypothesis discovery -- Patient engagement and consumerism -- Part IV. The future of translational informatics and knowledge-driven healthcare -- Future directions for translational informatics.
Format
e-Book
Location
Online
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11 records – page 1 of 1.