topic:"Microbiology" found 119 records - Provincial Hospitals Library Catalogue

Abdominal Sepsis : A Multidisciplinary Approach

https://libcat.nshealth.ca/en/permalink/provcat43191

Massimo Sartelli, Matteo Bassetti, Ignacio Martin-Loeches, editors. --Cham: Springer , c2018.

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Location: Online

This book examines in detail the topic of sepsis, with a focus on intra-abdominal sepsis. Particular attention is devoted to source control in the management of the infection, antimicrobial therapy and sepsis support, which represent the cornerstones of treating patients with abdominal sepsis. The importance of a multidisciplinary approach is highlighted not only by the instructive and informative sections on the acute manifestations of appendicitis, cholecystitis, and cholangitis, perforations…

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Other Authors: Sartelli, Massimo; Bassetti, Matteo; Martin-Loeches, Ignacio

Responsibility: Massimo Sartelli, Matteo Bassetti, Ignacio Martin-Loeches, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2018

Physical Description: 1 online resource (xi, 405 p.) : 49 illus., 34 illus. in color

Series Title: Hot topics in acute care surgery and trauma

ISBN: 9783319597041; 9783319597034 (print ed.); 9783319597058 (print ed.)

ISSN: 2520-8284

Subjects (MeSH): Digestive System Diseases - microbiology; Drug Resistance, Microbial; Intraabdominal Infections - diagnosis; Intraabdominal Infections - therapy; Sepsis - therapy

Specialty: Gastroenterology; Infectious Disease Medicine

Abstract: This book examines in detail the topic of sepsis, with a focus on intra-abdominal sepsis. Particular attention is devoted to source control in the management of the infection, antimicrobial therapy and sepsis support, which represent the cornerstones of treating patients with abdominal sepsis. The importance of a multidisciplinary approach is highlighted not only by the instructive and informative sections on the acute manifestations of appendicitis, cholecystitis, and cholangitis, perforations and diverticulitis, Clostridium difficile infection and the role of candida in abdominal sepsis, but also by an extensive discussion of issues including antimicrobial resistance, damage control surgery, principles of antimicrobial therapy, hemodynamic support, adjunctive therapies, and thromboprophylaxis. Abdominal sepsis is the host's systemic inflammatory response to intra-abdominal infections. It is associated with significant morbidity and mortality rates, and represents the second most common cause of sepsis-related mortality at intensive care units. Gathering contributions by authoritative experts from all around the world, this book will allow acute care surgeons, abdominal surgeons, intensive care clinicians, and students to broaden their understanding of intra-abdominal sepsis in daily clinical practice.

Contents: 1. Classifications and principles of treatment -- 2. Peritonitis and intra-peritoneal inflammatory mediators -- 3. Imaging diagnosis -- 4. Higk risk patients and prognostic factors -- 5. Acute appendicitis -- 6. Acute cholecystitis -- 7. Acute cholangitis -- 8 Pyogenic liver abscess -- 9. Gastroduodenal perforations -- 10. Small bowel perforations -- 11. Acute colonic diverticulitis -- 12. Post-operative peritonitis -- 13. Damage control surgery in managing abdominal sepsis -- 14. Ongoing peritonitis -- 15. Clostridium difficile infection -- 16. Complicated Intra-abdominal infections: Principles of Antimicrobial Therapy -- 17. Antimicrobial armamentarium -- 18. Antimicrobial resistance in intra-abdominal infections -- 19. The role of candida in abdominal sepsis -- 20. Use and interpretation of peritoneal swabs -- 21. Appropriate antimicrobial therapy in critically ill patients -- 22. Haemodynamic support -- 23. Adjunctive therapies -- 24. Impact and management of abdominal compartment syndrome in patients with abdominal sepsis -- 25. Tromboprohilaxis in patients with abdominal sepsis -- 26. Nutrition in patients with abdominal sepsis.

Format: e-Book

Location: Online

An atlas of the clinical microbiology of infectious diseases. Vol. 1, Bacterial agents

https://libcat.nshealth.ca/en/permalink/provcat22553

Bottone, Edward J. --Boca Raton, FL: Parthenon Publishing , 2006.

Call Number: WC 17 B751a 2006 v. 1 REF

Location: Dickson Building

Sub-Location: REFERENCE

Call Number: WC 17 B751a 2006 v. 1 REF

Author: Bottone, Edward J

Place of Publication: Boca Raton, FL

Publisher: Parthenon Publishing

Date of Publication: 2006

Physical Description: 160 p.

Series Title: Encyclopedia of visual medicine series

ISBN: 1842142194; 9781842142196

Subjects (MeSH): Communicable Diseases - microbiology - Atlases; Bacterial Infections - microbiology - Atlases

Format: Book

Location: Dickson Building

Sub-Location: REFERENCE

Loan Period: In library use

An atlas of the clinical microbiology of infectious diseases. Vol. 2, Viral, fungal and parasitic agents

https://libcat.nshealth.ca/en/permalink/provcat22554

Bottone, Edward J. --Abingdon, England: Taylor and Francis , 2006.

Call Number: WC 17 B751a 2006 v. 2 REF

Location: Dickson Building

Sub-Location: REFERENCE

Call Number: WC 17 B751a 2006 v. 2 REF

Author: Bottone, Edward J

Place of Publication: Abingdon, England

Publisher: Taylor and Francis

Date of Publication: 2006

Physical Description: 240 p.

ISBN: 1842142402; 9781842142400

Subjects (MeSH): Communicable Diseases - microbiology - Atlases; Mycoses - microbiology - atlases; Parasitic Diseases - microbiology - Atlases; Virus Diseases - microbiology - Atlases

Format: Book

Location: Dickson Building

Sub-Location: REFERENCE

Loan Period: In library use

Antibiotic Policies : Controlling Hospital Acquired Infection

https://libcat.nshealth.ca/en/permalink/provcat30848

Ian M. Gould, Jos W.M. van der Meer, editors. --New York, NY: Springer , c2012.

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Location: Online

Hospitals worldwide are currently suffering an epidemic of infections, generated in and spreading in those instituitions whose very "raison d'etre" is to protect and improve the health of their patients. This paradox comes at a time of possibly unprecedented investment in preventative measures (infection control). To better control these infections, however, we need to understand their causes, many of which are related, paradoxically, to the success of antibiotic therapy. It is possible that th…

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Other Authors: Gould, Ian M; Meer, Jos W.M van der

Responsibility: Ian M. Gould, Jos W.M. van der Meer, editors

Place of Publication: New York, NY

Publisher: Springer

Date of Publication: c2012

Physical Description: 1 online resource (xiii, 209 p. : 6 ill.)

ISBN: 9781441917348

Subjects (MeSH): Infection Control - organization & administration; Anti-Bacterial Agents; Bacterial Infections - drug therapy; Drug Resistance, Microbial

Subjects (LCSH): Medical virology; Microbiology; Infectious diseases

Abstract: Hospitals worldwide are currently suffering an epidemic of infections, generated in and spreading in those instituitions whose very "raison d'etre" is to protect and improve the health of their patients. This paradox comes at a time of possibly unprecedented investment in preventative measures (infection control). To better control these infections, however, we need to understand their causes, many of which are related, paradoxically, to the success of antibiotic therapy. It is possible that the golden era of antibiotics led subconsciously to a loss of emphasis on the importance of hygiene in the control of HAI. Moreover, the majority of HAIs are due to multiply antibiotic resistant bacteria whose emergence has been hastened by over-enthusiastic antibiotic prescribing. Accumulating evidence also suggests that antibiotics not only select for resistance but can actually increase the numbers of HAIs and even their virulence. This comprehensive compilation, written by eminent international researchers, explores these hypothesis in the context of recent epidemiology and evidence for the success of various antibiotic stewardship measures in controlling and even reversing resistance. It contains chapters by acclaimed authors on all the major causes of HAI, including MRSA, VRE, Clostridium difficile and multi resistant gram negative infections which are increasingly pan-resistant and untreatable; the nearest thing we have yet experienced to a "Doomsday bug". This book is an excellent source of information for students, researchers and practitioners in infection control, hospital epidemiology, antimicrobial prescribing and microbiology.

Contents: Healthcare Associated Infections: The Size of the Problem -- The Antibiotic Paradox -- The Epidemiology of Pan/Extreme Drug Resistance -- Hospital Antibiotic Stewardship to Control Resistance - how should it be done? -- Controlling Clostridium difficile infection and the role of antibiotic stewardship -- The control of MRSA -- The role of antibiotic policies in controlling VRE -- The control of ESBL producing bacteria -- Controlling Hospital-Acquired Infection due to Carbapenem-Resistant Enterobacteriaceae (CRE) -- Control of multi-drug resistant Acinetobacter infections -- The control of multidrug-resistant Pseudomonas: Insights into epidemiology and management -- Multidrug-resistant infections in low-resource health care settings -- Germ Shed Management in the United States -- Required actions.

Format: e-Book

Location: Online

Antimicrobial agents and chemotherapy

https://libcat.nshealth.ca/en/permalink/provcat17343

American Society of Microbiology

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Holdings: Vol 1, 1972 - (delayed 6 months)

Location: Online

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Publisher: American Society of Microbiology

Holdings: Vol 1, 1972 - (delayed 6 months)

ISSN: 0066-4804

Specialty: Microbiology

Format: e-Journal

Location: Online

Antimicrobial peptides and innate immunity

https://libcat.nshealth.ca/en/permalink/provcat32483

Pieter S. Hiemstra, Sebastian A. J. Zaat, editors. --Basel: Springer , c2013.

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Location: Online

Antimicrobial peptides have been the subject of intense research in the past decades, and are now considered as an essential part of the defense system in bacteria, plants, animals and humans. This book provides an update on these effector molecules of the innate immune system both for researchers who are already actively involved in the area, and for those with a general interest in the topic. The book starts with an overview of the evolution of cysteine-containing antimicrobial peptides (inc…

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Other Authors: Hiemstra, Pieter S; Zaat, Sebastian A. J

Responsibility: Pieter S. Hiemstra, Sebastian A. J. Zaat, editors

Place of Publication: Basel

Publisher: Springer

Date of Publication: c2013

Physical Description: 1 online resource (xi, 384 p. : 38 ill., 23 ill. in color)

Series Title: Progress in inflammation research

ISBN: 9783034805414

Subjects (MeSH): Antimicrobial Cationic Peptides - immunology; Immunity, Innate - immunology

Subjects (LCSH): Immunology; Microbiology; Infectious diseases; Biochemistry

Abstract: Antimicrobial peptides have been the subject of intense research in the past decades, and are now considered as an essential part of the defense system in bacteria, plants, animals and humans. This book provides an update on these effector molecules of the innate immune system both for researchers who are already actively involved in the area, and for those with a general interest in the topic. The book starts with an overview of the evolution of cysteine-containing antimicrobial peptides (including defensins), and the role of these peptides in host defense in plants and micro-organisms. The realization that antimicrobial peptides also display functions distinct from their direct antimicrobial action is the focus of the next chapters, and puts these peptides center stage in immunity and wound repair. Further chapters discuss the role of antimicrobial peptides in disease, by providing an overview of mechanisms in bacterial resistance to antimicrobial peptides and a discussion of their role in inflammatory bowel disease, cystic fibrosis lung disease and chronic obstructive pulmonary disease. Finally, the book shows how knowledge of the function of antimicrobial peptides and their regulation can be used to design new therapies for inflammatory and infectious disorders. This is a very important area of research because of the increase in resistance of micro-organisms to conventional antibiotics. Therefore the use of synthetic or recombinant peptides, or agents that stimulate the endogenous production of antimicrobial peptides, provides an attractive alternative for conventional antibiotics.

Contents: Evolution of Antimicrobial Peptides: a View From the Cystine Chapel -- Innate immunity in plants: the role of antimicrobial peptides -- Antimicrobial peptides produced by microorganisms -- LL-37: an immunomodulatory antimicrobial host defence peptide -- Wound Repair and Antimicrobial Peptides -- WAPing out pathogens and disease in the mucosa-roles for SLPI and trappin-2 -- Histatins: multifunctional salivary antimicrobial peptides -- Structure-function relationships of antimicrobial chemokines -- Mechanisms and Significance of Bacterial Resistance to Human Cationic Antimicrobial Peptides -- Antimicrobial peptides and inflammatory bowel disease -- Cystic Fibrosis and Defective Airway Innate Immunity -- Antimicrobial peptides in chronic obstructive pulmonary disease -- Host defense peptides: Immune modulation and antimicrobial activity in vivo -- Helping the host induction of antimicrobial peptides as a novel therapeutic strategy against infections.

Format: e-Book

Location: Online

Bacterial Genomes and Infectious Diseases

https://libcat.nshealth.ca/en/permalink/provcat30077

edited by Voon L. Chan, Philip M. Sherman, Billy Bourke. --Totowa, NJ: Humana Press , c2006.

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Location: Online

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Author: Chan, Voon L

Other Authors: Sherman, Philip M; Bourke, Billy

Responsibility: edited by Voon L. Chan, Philip M. Sherman, Billy Bourke

Place of Publication: Totowa, NJ

Publisher: Humana Press

Date of Publication: c2006

ISBN: 9781597451529

Subjects (MeSH): Communicable Diseases - genetics; Bacteria - genetics; Virulence - genetics

Subjects (LCSH): Infectious diseases; Microbiology; Genetics

Format: e-Book

Location: Online

Bacterial Infections and the Kidney

https://libcat.nshealth.ca/en/permalink/provcat41705

Anjali A. Satoskar, Tibor Nadasdy, editors. --Cham: Springer , 2017.

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Location: Online

This text is designed to present a comprehensive and state-of the-art but practical approach to the diagnosis and management of bacterial infection associated renal disease. The chapters address the different types of glomerular, tubulointerstitial and vascular diseases, associated with bacterial infections, describe diagnostic pitfalls, provide differential diagnosis and discuss treatment and management. Easy to follow diagnostic algorithms and tables are included for practical usefulness. The…

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Other Authors: Satoskar, Anjali A.; Nadasdy, Tibor

Responsibility: Anjali A. Satoskar, Tibor Nadasdy, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: 2017

Physical Description: 1 online resource (xii, 215 pages) : 93 illus., 77 illus. in color

ISBN: 9783319527925; 9783319527901 (print ed.)

Subjects (MeSH): Bacterial Infections - prevention & control; Kidney Diseases - microbiology

Abstract: This text is designed to present a comprehensive and state-of the-art but practical approach to the diagnosis and management of bacterial infection associated renal disease. The chapters address the different types of glomerular, tubulointerstitial and vascular diseases, associated with bacterial infections, describe diagnostic pitfalls, provide differential diagnosis and discuss treatment and management. Easy to follow diagnostic algorithms and tables are included for practical usefulness. The text provides a large number of color microphotographs, illustrations and each chapter refers to the most important up to date literature in the area. All chapters are written by experts in the field and will include the most up-to-date clinical information. A comprehensive but user friendly resource on renal complications of bacterial infection, such as this book, is overdue, particularly now in the era of staphylococcus epidemic and emerging new resistant bacterial strains. Bacterial Infections and the Kidney will be an important resource for pathologists, nephrologists, general internists, infectious disease specialists, and urologists. Transplant surgeons may find the chapter on transplant pyelonephritis very useful.

Contents: 1. Acute Poststreptococcal Glomerulonephritis -- 2. Staphylococcus Infection-Associated Glomerulonephritis -- 3. Glomerulonephritis Associated with Other Bacterial Infections -- 4. Endocarditis-Associated Glomerulonephritis -- 5. The Management of Bacterial Infection-Associated Glomerulonephritis -- 6. Infection-Associated Thrombotic Microangiopathy -- 7. Direct Bacterial Infection of the Renal Parenchyma: Pyelonephritis in Native Kidneys -- 8. Bacterial Infection of the Renal Allograft.

Format: e-Book

Location: Online

Bacterial Infections of Humans : Epidemiology and Control

https://libcat.nshealth.ca/en/permalink/provcat30400

edited by Philip S. Brachman, Elias Abrutyn. (3rd ed.) --Boston, MA: Springer-Verlag US , c2009.

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Location: Online

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Author: Brachman, Philip S

Other Authors: Abrutyn, Elias

Responsibility: edited by Philip S. Brachman, Elias Abrutyn

Edition: 3rd ed.

Place of Publication: Boston, MA

Publisher: Springer-Verlag US

Date of Publication: c2009

ISBN: 9780387098432

Subjects (MeSH): Bacterial Infections - epidemiology; Bacterial Infections - prevention & control

Subjects (LCSH): Microbiology; Infectious diseases; Epidemiology; Public health

Format: e-Book

Location: Online

Bacterial Pathogens and Their Virulence Factors

https://libcat.nshealth.ca/en/permalink/provcat43364

Douglas I. Johnson. --Cham: Springer , c2018.

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Location: Online

Bacterial Pathogens and their Virulence Factors contains a detailed description of 32 major bacterial pathogens that affect human health and their associated virulence determinants. Chapter 1 gives an overview of the different types and classes of general virulence factors involved in host cell adherence and invasion, dissemination within the host, host cell damage, and evasion of host defense systems, as well as mechanisms by which these virulence factors are regulated. Chapters 2 through 33 g…

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Author: Johnson, Douglas I.

Responsibility: Douglas I. Johnson

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2018

Physical Description: 1 online resource (xv, 461 p.) : 130 illus., 114 illus. in color

ISBN: 9783319676517; 9783319676500 (print ed.); 9783319676524 (print ed.); 9783319884608 (print ed.)

Subjects (MeSH): Bacteria - pathogenicity; Bacterial Infections - physiopathology; Bacterial Infections - prevention & control; Virulence Factors

Specialty: Infectious Disease Medicine; Microbiology

Abstract: Bacterial Pathogens and their Virulence Factors contains a detailed description of 32 major bacterial pathogens that affect human health and their associated virulence determinants. Chapter 1 gives an overview of the different types and classes of general virulence factors involved in host cell adherence and invasion, dissemination within the host, host cell damage, and evasion of host defense systems, as well as mechanisms by which these virulence factors are regulated. Chapters 2 through 33 give concise descriptions of the disease states associated with the 32 bacterial genera and their major pathogenic species, along with an in-depth description of the individual virulence factors that have been found to be functionally involved in pathogenicity. A detailed bibliography derived from primary literature and review articles accompanies each of these chapters, allowing the reader to delve more deeply into individual pathogens and their virulence determinants.Chapter 34 discusses the exciting possibilities and initial successes of using detailed information on a pathogen's virulence toolkit to design new therapeutics aimed at specific virulence traits.

Contents: Preface -- Bacterial Virulence Factors -- Part I. Gram-Positive Bacterial Pathogens -- Bacillus spp -- Clostridium spp -- Corynebacterium spp -- Enterococcus spp -- Listeria spp -- Mycobacterium spp -- Propionibacterium spp -- Staphylococcus spp -- Streptococcus spp -- Part II. Gram-Negative Bacterial Pathogens -- Bacteroides spp -- Bordetella spp -- Borrelia spp -- Campylobacter spp -- Escherichia spp -- Francisella spp -- Haemophilus spp -- Helicobacter spp -- Klebsiella spp -- Legionella spp -- Leptospira spp -- Neisseria spp -- Nocardia spp -- Proteus spp -- Pseudomonas spp -- Rickettsia spp -- Salmonella spp -- Shigella spp -- Treponema spp -- Vibrio spp -- Yersinia spp -- Chlamydia spp -- Mycoplasma spp -- Anti-Virulence Factor Therapeutics.

Format: e-Book

Location: Online

Basic Microbiology and Infection Control for Midwives

https://libcat.nshealth.ca/en/permalink/provcat44205

Elisabeth Presterl, Magda Diab-El Schahawi, Jacqui S. Reilly, editors. --Cham: Springer , 2019.

Available Online: View e-Book

Location: Online

This book provides an evidence-based, practical approach to the diagnosis and treatment of the most frequent fungal infections in a general hospital. It offers a comprehensive overview of the basic medical and scientific background of fungal infections and carefully explains and discusses epidemiology, pathogenesis, and clinical presentation. Readers will acquire a good and clear perception of invasive fungal infections, including diagnosis and treatment. This user-friendly resource not only se…

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Other Authors: Presterl, Elisabeth; Diab-El Schahawi, Magda; Reilly, Jacqui S.

Responsibility: Elisabeth Presterl, Magda Diab-El Schahawi, Jacqui S. Reilly, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: 2019

Physical Description: 1 online resource (xvii, 210 p.) : 6 illus., 5 illus. in color

ISBN: 9783030020262; 9783030020255 (Print ed.); 9783030020279 (Print ed.)

Subjects (MeSH): Communicable Diseases; Disinfection; Infection Control; Midwifery; Mycoses; Virus Diseases

Specialty: Infectious Disease Medicine; Microbiology; Obstetrics

Abstract: This book provides an evidence-based, practical approach to the diagnosis and treatment of the most frequent fungal infections in a general hospital. It offers a comprehensive overview of the basic medical and scientific background of fungal infections and carefully explains and discusses epidemiology, pathogenesis, and clinical presentation. Readers will acquire a good and clear perception of invasive fungal infections, including diagnosis and treatment. This user-friendly resource not only serves as a valuable tool in clinical management, but also provides the basis for further research questions and studies in this particular field. It will be a useful companion for midwives as well as for doctors, medical and pharmacy students, nurses and other healthcare professionals.

Contents: 1. General Definitions -- 2. Infections and Infectious Doctrine -- 3. Hand Hygiene -- 4. Medical Instruments and Devices -- 5. Reprocessing: Cleansing, Disinfection, Sterilization -- 6. Basic Principles and Introduction to Disinfectants and Antiseptics for Skin, Mucosa, and Wounds -- 7. Basics of Medical Microbiology -- 8. Bacteriology: Selected Bacteria and Diseases -- 9. Hospital Infections -- 10. Antimicrobial Agents (Antibiotics) -- 11. Multiresistant Microorganisms and Infection Control -- 12. General and Specific Virology - 13. Specific Virology: Viruses as Diseases -- 14. Gastroenteritis: Gastrointestinal Infections -- 15. Blood-Borne Viruses: HIV, Hepatitis B, and Hepatitis C -- 16. Puncture Wounds and Needle-Related Injuries -- 17. Medical Mycology: Fungal Infections -- 18. Parasites and Parasitic Diseases -- 19. Epidemiology -- 20. Basic Immunology -- 21. Immunizations -- 22. Household Hygiene -- 23. Disinfestation -- 24. Environmental Medicine.

Format: e-Book

Location: Online

Breath Odors : Origin, Diagnosis, and Management

https://libcat.nshealth.ca/en/permalink/provcat29457

by Nir Sterer, Mel Rosenberg. --Berlin, Heidelberg: Springer-Verlag , c2011.

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Location: Online

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Author: Sterer, Nir

Other Authors: Rosenberg, Mel

Responsibility: by Nir Sterer, Mel Rosenberg

Place of Publication: Berlin, Heidelberg

Publisher: Springer-Verlag

Date of Publication: c2011

ISBN: 9783642193125

Subjects (MeSH): Halitosis; Oral Health; Diagnosis, Oral - methods

Subjects (LCSH): Dentistry; Otorhinolaryngology; Microbiology

Format: e-Book

Location: Online

Buruli Ulcer : Mycobacterium Ulcerans Disease

https://libcat.nshealth.ca/en/permalink/provcat43940

Gerd Pluschke, Katharina Röltgen, editors. --Cham: Springer , 2019.

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Access: Open access

Location: Online

A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of …

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Other Authors: Pluschke, Gerd; Röltgen, Katharina

Responsibility: Gerd Pluschke, Katharina Röltgen, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: 2019

Physical Description: 1 online resource (x, 287 p.) : 34 illus., 30 illus. in color

ISBN: 9783030111144; 9783030111137 (Print ed.); 9783030111151 (Print ed.)

Subjects (MeSH): Mycobacterium Infections, Nontuberculous; Mycobacterium ulcerans - pathogenicity

Specialty: Communicable Diseases; Microbiology

Abstract: A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.

Contents: Buruli Ulcer: History and Disease Burden -- Buruli Ulcer in Africa -- Buruli Ulcer in Australia -- Mycobacterium Ulcerans Infection in French Guiana; Current State of Knowledge -- Buruli Ulcer in Japan -- Population Genomics and Molecular Epidemiology of Mycobacterium Ulcerans -- Mycolactone: More Than Just a Cytotoxin -- The Immunology of Buruli Ulcer -- Buruli Ulcer in Animals and Experimental Infection Models -- Laboratory Diagnosis of Buruli Ulcer: Challenges and Future Perspectives -- Antimicrobial Treatment of Mycobacterium Ulcerans Infection -- Thermotherapy of Buruli Ulcer -- Secondary Infection of Buruli Ulcer Lesions -- Management of BU-HIV Co-infection -- Social Science Contributions to BU Focused Health Service Research in West-Africa -- Transdisciplinary Research and Action to Stop Buruli Ulcer– A Case Study from Philanthropy.