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60 years of survival outcomes at the University of Texas MD Anderson Cancer Center

https://libcat.nshealth.ca/en/permalink/provcat32423
M. Alma Rodriguez, Ronald S. Walters, Thomas W. Burke, editors. --New York, NY: Springer , c2013.
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This unique book provides a retrospective analysis of the changes in survival outcomes at The University of Texas M.D. Anderson Cancer Center over the past six decades. Since opening its doors in 1944, M.D. Anderson has kept a continuous, uninterrupted data repository of the treatment and outcomes of each of its patients. It is this visionary database from the Center's tumor registry which makes this groundbreaking book possible. Tracking results across time, the book shows radical shifts in ou…
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Other Authors
Rodriguez, M. Alma
Walters, Ronald S
Burke, Thomas W
Responsibility
M. Alma Rodriguez, Ronald S. Walters, Thomas W. Burke, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xiii, 346 p. : 124 ill. in color)
ISBN
9781461451976
Subjects (MeSH)
Academies and Institutes - history
History, 20th century
History, 21st century
Neoplasms - epidemiology
Neoplasms - therapy
Registries
Survival Analysis
Texas - epidemiology
Treatment Outcome
Subjects (LCSH)
Oncology
Epidemiology
Abstract
This unique book provides a retrospective analysis of the changes in survival outcomes at The University of Texas M.D. Anderson Cancer Center over the past six decades. Since opening its doors in 1944, M.D. Anderson has kept a continuous, uninterrupted data repository of the treatment and outcomes of each of its patients. It is this visionary database from the Center's tumor registry which makes this groundbreaking book possible. Tracking results across time, the book shows radical shifts in outcomes trends, where great progress has been made, and where there is still a long way to go, and offers a snapshot of the parallel history of developments in care. Such data is crucial to informing how patients are counseled, how treatment decisions are determined, and how prognoses are made. 60 Years of Survival Outcomes at The University of Texas M.D. Anderson Cancer Center is the only book to concurrently present longitudinal data on survival outcomes across the spectrum of rare and common cancers. Each chapter deals with a specific disease site, discussing current management approaches and presenting key data replete with illustrative charts, graphs, and tables. With the resources available only to the practitioners at this inimitable institution, this book heralds a cornerstone moment in the study of survival outcomes and the depth of our knowledge of cancer care.
Contents
Ch. 1:Introduction -- Ch. 2:History of MD Anderson's Tumor Registry -- Ch. 3:Statistical Methods -- Ch. 4:Breast Cancer -- Ch. 5:Prostate Cancer -- Ch. 6:Non-Small Cell Lung Cancer -- Ch. 7:Small Cell Lung Cancer -- Ch. 8:Colon Cancer -- Ch. 9:Ovarian Cancer -- Ch. 10:Cervical Cancer -- Ch. 11:Endometrial Cancer -- Ch. 12:Pancreatic Cancer (Exocrine) -- Ch. 13:Kidney Cancer -- Ch. 14:Bladder Cancer -- Ch. 15:Cutaneous Melanoma -- Ch. 16:Liver Cancer -- Ch. 17:Esophageal Cancer -- Ch. 18:Gastric Cancer -- Ch. 19:Acute Myeloid Leukemia -- Ch. 20:Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma -- Ch. 21:Hodgkin Lymphoma -- Ch. 22:Non-Hodgkin Indolent B-Cell Lymphoma -- Ch. 23:Non-Hodgkin Aggressive B-Cell Lymphoma -- Ch. 24:Multiple Myeloma -- Ch. 25:Head and Neck Cancer -- Ch. 26:Thyroid Cancer -- Ch. 27:Soft Tissue Sarcomas -- Ch. 28:Sarcomas of Bone -- Index.
Format
e-Book
Location
Online
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Abeloff's clinical oncology

https://libcat.nshealth.ca/en/permalink/provcat43446
Niederhuber, John. (5th ed.) --Philadelphia, PA: Elsevier Saunders , 2014.
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Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
Location
Online
Author
Niederhuber, John
Edition
5th ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Date of Publication
2014
Physical Description
online resource
ISBN
9781455728657
Subjects (MeSH)
Neoplasms - therapy
Medical Oncology - methods
Access
Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
Format
e-Book
Location
Online
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Abeloff's clinical oncology

https://libcat.nshealth.ca/en/permalink/provcat32179
[edited by] John E. Niederhuber, James O. Armitage, Michael B. Kastan ...[et al.]. (6th ed.) --Philadelphia, PA: Elsevier , c2020.
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Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment…
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Niederhuber, John E.
Responsibility
[edited by] John E. Niederhuber, James O. Armitage, Michael B. Kastan ...[et al.]
Edition
6th ed.
Alternate Title
Clinical oncology
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
c2020
Physical Description
1 online resource, 2072 p.
ISBN
9780323476744
Subjects (MeSH)
Neoplasms - therapy
Medical Oncology - methods
Subjects (LCSH)
Oncology
Cancer--Treatment
Specialty
Medical Oncology
Abstract
Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up.
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Format
e-Book
Location
Online
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Active Surveillance for Localized Prostate Cancer : A New Paradigm for Clinical Management

https://libcat.nshealth.ca/en/permalink/provcat43371
Laurence Klotz, editor. (Second edition) --Cham: Humana Press , c2018.
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This fully updated and revised new edition provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in prostate cancer. The book reviews new data about molecular characteristics of the disease, profiles the new grading system for prostate cancer introduced in 2015, and provides new perspectives about imaging of prostate cancer, as well as the role of targeted biopsies. The text summarizes the…
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Klotz, Laurence
Responsibility
Laurence Klotz, editor
Edition
Second edition
Place of Publication
Cham
Publisher
Humana Press
Date of Publication
c2018
Physical Description
1 online resource (xii, 250 p.) : 39 illus., 27 illus. in color
Series Title
Current clinical urology
ISBN
9783319627106
9783319627090 (print ed.)
9783319627113 (print ed.)
9783319873756 (print ed.)
ISSN
2197-7194
Subjects (MeSH)
Disease Progression
Medical Overuse - prevention & control
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - therapy
Watchful Waiting
Specialty
Medical Oncology
Urology
Abstract
This fully updated and revised new edition provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in prostate cancer. The book reviews new data about molecular characteristics of the disease, profiles the new grading system for prostate cancer introduced in 2015, and provides new perspectives about imaging of prostate cancer, as well as the role of targeted biopsies. The text summarizes the role of biomarkers and MRI in patient selection and management and details the world wide results of active surveillance. Specific chapters address communication and ethical issues, QOL outcomes, economic aspects, and psycho-social aspects of surveillance. The role of focal therapy for low risk disease is summarized, and the data supporting preventive interventions during surveillance reviewed. This text will serve as a very useful resource for physicians and researchers dealing with, and interested in this common malignancy, as it provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.
Contents
Cancer Overdiagnosis and Overtreatment -- Can We Screen and Still Reduce Overdiagnosis? -- The Role of Fear in Overdiagnosis and Overtreatment -- Ethical and Legal Considerations in Active Surveillance for Prostate Cancer -- Gleason 6 Tumors Should Still Be Labeled As Cancer -- Risk Based Selection for Active Surveillance -- Surveillance at the Margins: Management of High Volume Gleason 6, PSA>10, or Gleason 3+4 -- How Should Patients on Active Surveillance be Followed? -- Triggers for Intervention -- MR Imaging in Prostate Tumor Volume Assessment: How Accurate? -- Can MRI Replace Biopsy in Men on Surveillance? -- Tissue Based Markers for Risk Prediction -- International AS Registry: The Movember Foundation's Global Action Plan Prostate Cancer Active Surveillance Initiative -- Better Informed Decision Making to Optimize Patient Selection -- How Does QOL Compare Between Surveillance and Active Treatment? -- The Potential Benefits of Diet and Physical Activity among Active Surveillance Patients with Low-Burden Prostate Cancer -- Is there a Role for Pharmacologic Manipulation to Prevent Progression in Men on Active Surveillance? The Role of 5-ARIs, Statins, and Metformin -- The Update of Active Surveillance around the World: Utilization and Outcomes -- Tissue Preservation: Active Surveillance and Focal Therapy as Complimentary Strategies -- The Economics of Active Surveillance for Prostate Cancer -- Research Questions in Active Surveillance.
Format
e-Book
Location
Online
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Active Surveillance for Localized Prostate Cancer : A New Paradigm for Clinical Management

https://libcat.nshealth.ca/en/permalink/provcat31028
Laurence Klotz, editor. --New York, NY: Humana Press , c2012.
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Active Surveillance for Localized Prostate Cancer: A New Paradigm for Clinical Management will serve as a useful resource for physicians dealing with, and interested in, this complex and evolving branch of prostate cancer management. The book will also be of interest to scientifically literate patients and their families. The volume provides an introduction to the concept of active surveillance in oncology in general and prostate cancer specifically. The primary focus is to provide a comprehens…
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Other Authors
Klotz, Laurence
Responsibility
Laurence Klotz, editor
Place of Publication
New York, NY
Publisher
Humana Press
Date of Publication
c2012
Physical Description
1 online resource (xi, 208 p. : 33 ill., 22 ill. in color)
Series Title
Current clinical urology
ISBN
9781617799129
Subjects (MeSH)
Disease Progression
Early Diagnosis
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - therapy
Watchful Waiting
Subjects (LCSH)
Oncology
Urology
Abstract
Active Surveillance for Localized Prostate Cancer: A New Paradigm for Clinical Management will serve as a useful resource for physicians dealing with, and interested in, this complex and evolving branch of prostate cancer management. The book will also be of interest to scientifically literate patients and their families. The volume provides an introduction to the concept of active surveillance in oncology in general and prostate cancer specifically. The primary focus is to provide a comprehensive guide to the management of patients on surveillance. The volume covers the many complexities and nuances to this approach including, patient selection, risk assessment, how to overcome 'cancer hysteria' when counseling patients, identifying appropriate triggers for intervention, use of PSA kinetics and MR imaging information, technique and frequency of biopsies, secondary prevention interventions, and the relative roles of surveillance and focal therapy.
Contents
1. The Problem of Cancer Overdiagnosis and Overtreatment -- 2. Patient Selection for Active Surveillance -- 3. Predicting High Risk Disease Using Tissue Biomarkers -- 4. Predicting High Risk Disease Using Serum and DNA Biomarkers -- 5. Triggers for Intervention in Men on Surveillance -- 6. The Role of MRI in Active Surveillance -- 7. Active Surveillance: The European Experience -- 8. Active Surveillance: The Canadian Experience -- 9. Psychosocial Aspects of Active Surveillance -- 10. Statistical Considerations for Patient Selection and Triggers for Intervention in Active Surveillance -- 11. Interpreting PSA Kinetics using GLMM Technique -- 12. The Potential Benefits of Diet and Physical Activity among Active Surveillance Patients with Low-Burden Prostate Cancer -- 13. The Role of 5[alpha]-Reductase Inhibitors (5-ARIs) in Expectant Management of Low Risk Prostate Cancer -- 14. Urologists' Opinion on Active Surveillance: United States vs. the Netherlands -- 15. Clinical "Pearls" in Managing Patients on Surveillance -- 16. Active Surveillance, Focal Therapy and the Future -- 17. The Economics of Active Surveillance for Prostate Cancer -- 18. The Future of Active Surveillance.
Format
e-Book
Location
Online
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Acupuncture and Moxibustion as an Evidence-based Therapy for Cancer

https://libcat.nshealth.ca/en/permalink/provcat31284
William C.S. Cho, editor. --Dordrecht: Springer , c2012.
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Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments' side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in narrowing the knowledge…
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Cho, William C.S.
Responsibility
William C.S. Cho, editor
Place of Publication
Dordrecht
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xi, 354 p. : 25 ill., 18 ill. in color)
Series Vol.
v. 3
Series Title
Evidence-based anticancer complementary and alternative medicine
ISBN
9789400748330
Subjects (MeSH)
Acupuncture Therapy
Evidence-Based Medicine
Moxibustion
Neoplasms - therapy
Subjects (LCSH)
Oncology
Alternative medicine
Acupuncture
Abstract
Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments' side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in narrowing the knowledge gap to explore the scientific and evidence-based knowledge of CAM in the anticancer field. With this aim, an unparalleled undertaking of a book series is launched to structurally consolidate this area. Although acupuncture and moxibustion have been practiced for millennia, they have come under scientific investigation only recently. Acupuncture and moxibustion have been used clinically to treat cancer-related symptoms (e.g. cancer pain, anxiety, depression and insomnia), manage treatment-induced side effects (e.g. hot flashes, nausea and vomiting) and enhance immunity (e.g. blood cell count, lymphocyte and natural killer cell activity). This is the first book manages to provide comprehensive and updated scientific evidence of the effectiveness of acupuncture and moxibustion intervention for cancer care. Laboratory and animal studies have uncovered the mechanisms of acupuncture and moxibustion for cancer therapy. Promising results of most clinical trials show the efficacy and safety of acupuncture and moxibustion in cancer management. This book consists of fifteen chapters which address a range of important aspects that will impact on the application of acupuncture and moxibustion. An overview of the safety and side effects of acupuncture and moxibustion for cancer care are also covered. In addition, the integration of acupuncture with Western medicine in cancer treatment and recent clinical trials are included as well. Opinion leaders around the world have teamed up to pursue a thorough and up-to-date review of the area, this volume will contribute great to the cancer, clinical and academic community by providing evidence-based information on the efficacy of acupuncture and moxibustion as an anticancer therapy.
Contents
Prelims -- 1. An Overview of Acupuncture and Moxibustion for Cancer Care -- 2. The Mechanistic Studies of Acupuncture and Moxibustion -- 3. Acupuncture for Cancer Pain -- 4. Acupuncture for the Treatment of Hot Flashes in Cancer Patients -- 5. Acupuncture and Moxibustion for Cancer-related Symptoms -- 6. Use of Acupuncture and Moxibustion in the Control of Anticancer Therapy-induced Nausea and Vomiting -- 7. Acupuncture and Moxibustion for Side Effects of Chemotherapy in Cancer Patients -- 8. Acupuncture for the Treatment of Symptoms Associated with Radiation Therapy -- 9. Quality of Life of Cancer Patients after Acupuncture and Moxibution Treatment -- 10. Acupuncture and Moxibustion for Palliative and Supportive Cancer Care -- 11. Is Acupuncture or Moxibustion Better Than a Sham or Placebo-treatment?-12. Safety and Side Effects of Acupuncture and Moxibustion as a Therapy for Cancer -- 13. Acupuncture and Moxibustion in Animal Models of Cancer -- 14. Integrating Acupuncture with Western Medicine in Cancer Treatment -- 15. Recent Clinical Trials of Acupuncture for Cancer Patients. Index.
Format
e-Book
Location
Online
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Adjuvant therapy for breast cancer

https://libcat.nshealth.ca/en/permalink/provcat30193
--Boston, MA: Springer-Verlag US , c2009.
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Online
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Other Authors
Castiglione, Monica
Piccart, Martine J
Place of Publication
Boston, MA
Publisher
Springer-Verlag US
Date of Publication
c2009
Series Vol.
151
Series Title
Cancer treatment and research
ISBN
9780387751153
Subjects (MeSH)
Adjuvants, Pharmaceutic
Breast Neoplasms - therapy
Chemotherapy, Adjuvant
Radiotherapy, Adjuvant
Subjects (LCSH)
Oncology
Gynecology
Format
e-Book
Location
Online
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Adult brain tumour handbook

https://libcat.nshealth.ca/en/permalink/provcat25617
Brain Tumour Foundation of Canada. (6th ed.) --London, ON: Brain Tumour Foundation of Canada , 2012.
Call Number
WL 358 B814a 2011
Location
Nova Scotia Hospital
Call Number
WL 358 B814a 2011
Corporate Author
Brain Tumour Foundation of Canada
Edition
6th ed.
Alternate Title
Adult brain tumor handbook
Place of Publication
London, ON
Publisher
Brain Tumour Foundation of Canada
Date of Publication
2012
Physical Description
296 p.
Subjects (MeSH)
Brain Neoplasms - Popular Works
Brain Neoplasms - therapy - Popular Works
Format
Book
Publication Type
Handbook
Location
Nova Scotia Hospital
Copies
3
Loan Period
3 weeks
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Advances in breast cancer management

https://libcat.nshealth.ca/en/permalink/provcat30353
(2nd ed.) --Boston, MA: Springer US , c2008.
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Location
Online
Available Online
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Other Authors
Gradishar, William J
Wood, William C
Edition
2nd ed.
Place of Publication
Boston, MA
Publisher
Springer US
Date of Publication
c2008
Series Vol.
141
Series Title
Cancer treatment and research
ISBN
9780387731612
Subjects (MeSH)
Breast Neoplasms - prevention & control
Breast Neoplasms - therapy
Subjects (LCSH)
Gynecology
Oncology
Format
e-Book
Location
Online
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Advances in diagnosis and management of ovarian cancer

https://libcat.nshealth.ca/en/permalink/provcat33783
Samir A. Farghaly, editor. --New York: Springer , c2014.
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This volume is an up-to-date resource on the international state-of-the-art in the diagnosis and management of ovarian cancer. While this devastating disease has been considered mainly a disease of the Western hemisphere, the book moves beyond our conventional understanding and embraces knowledge from around the world. It focuses on recent advances in diagnosis, including genetic screening; improvements and expanded choices in management, such as gene therapy and the optimization of chemotherap…
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Farghaly, Samir A
Responsibility
Samir A. Farghaly, editor
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xv, 270 pages)
ISBN
9781461482710 (electronic bk.)
9781461482703
Subjects (MeSH)
Ovarian Neoplasms - diagnosis
Ovarian Neoplasms - therapy
Subjects (LCSH)
Ovaries - Cancer - Diagnosis
Ovaries - Cancer - Treatment
Oncology
Gynecology
Abstract
This volume is an up-to-date resource on the international state-of-the-art in the diagnosis and management of ovarian cancer. While this devastating disease has been considered mainly a disease of the Western hemisphere, the book moves beyond our conventional understanding and embraces knowledge from around the world. It focuses on recent advances in diagnosis, including genetic screening; improvements and expanded choices in management, such as gene therapy and the optimization of chemotherapeutic agents; and the latest laparoscopic and robotic surgical techniques. Further chapters address histopathologic features of this disease, and related psychosocial and quality of-life-issues.
Contents
1. Epidemiology of Ovarian Cancer: An Update -- 2. Genetic Risks of Ovarian Cancer -- 3. Ovarian Cancer Screening and Early Detection -- 4. Surface Epithelial Tumours of the Ovary -- 5. Pathology of Non-epithelial Malignancies of the Ovary -- 6. Strategies for the Management of Ovarian Cancer -- 7. Management of Hereditary Ovarian–Breast Cancer -- 8. Ovarian Cancer in the Pediatric Population -- 9. Management of Patients with Early-Stage Ovarian Cancer -- 10. Treatment of Advanced Stage Ovarian Cancer -- 11. Diagnosis and Management of Epithelial Ovarian Cancer with Peritoneal Metastases -- 12. Targeted Molecular Therapy for Patients with Ovarian Cancer -- 13. Psychological Aspects of Hereditary and Non-hereditary Ovarian Cancer -- 14. Quality of Life in Patients with Ovarian Cancer.
Format
e-Book
Location
Online
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Advances in tumor immunology and immunotherapy

https://libcat.nshealth.ca/en/permalink/provcat33290
Joseph D. Rosenblatt, Eckhard R. Podack, Glen N. Barber, Augusto Ochoa, editors. --New York: Springer , c2014.
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Recent advances in understanding of fundamental immunology have created new insights into the dynamic interactions between tumors and the immune system. This includes new understanding of T- and B-cell interaction, immune inhibitory mechanisms including the biology of T regulatory cells, myeloid suppressor cells, and dendritic cell subsets. Enhanced understanding of mechanisms underlying T-cell anergy such as arginine deprivation, immunosuppressive cytokines, defective innate and interferon res…
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Rosenblatt, Joseph D
Responsibility
Joseph D. Rosenblatt, Eckhard R. Podack, Glen N. Barber, Augusto Ochoa, editors
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (ix, 371 pages)
Series Title
Current cancer research
ISBN
9781461488095 (electronic bk.)
9781461488088
Subjects (MeSH)
Antigens, Neoplasm - immunology
Neoplasms - immunology
Neoplasms - therapy
T-Lymphocytes, Cytotoxic - immunology
Immunotherapy - methods
Subjects (LCSH)
Tumors - Immunological aspects
Cancer - Immunological aspects
Antigens, Neoplasm - immunology
Neoplasms - therapy
T-Lymphocytes, Cytotoxic - immunology
Cancer - Immunotherapy
Neoplasms - Immunology
Abstract
Recent advances in understanding of fundamental immunology have created new insights into the dynamic interactions between tumors and the immune system. This includes new understanding of T- and B-cell interaction, immune inhibitory mechanisms including the biology of T regulatory cells, myeloid suppressor cells, and dendritic cell subsets. Enhanced understanding of mechanisms underlying T-cell anergy such as arginine deprivation, immunosuppressive cytokines, defective innate and interferon response pathways, and NKG2D downregulation have all provided new insight into suppression of anti-tumors.
Contents
Part I. Immune Activation, Suppression and Manipulation of the Immune Antitumor Response -- Myeloid-Derived Suppressor Cells in Cancer -- The Role of B Cells in Shaping the Antitumor Immune Response -- Heat-Shock Protein-Based Cancer Immunotherapy -- Activation of NK Cell Responses and Immunotherapy of Cancer -- Induction of Tumor Immunity by Targeted Inhibition of Nonsense-Mediated mRNA Decay -- Employing T Cell Homeostasis as an Antitumor Strategy -- Adoptive Cell Therapy of Systemic Metastases Using erbB-2-Specific T Cells Redirected with a Chimeric Antibody-Based Receptor -- Part II. Evolving Clinical Immunotherapeutic Strategies -- Immunotherapy in Renal Cell Carcinoma -- Adoptive T-Cell Transfer as a Clinical Antitumor Strategy for Hematologic Malignancies -- Bifunctional Antibodies: Preclinical and Clinical Applications -- Clinical Development of Antibody-Fusion Proteins for Cancer Therapy -- Immunologic Outcomes of Allogeneic Stem Cell Transplantation: Graft-Versus-Host and Graft-Versus-Leukemia Responses and Implications for Future Therapy -- The Immune System in Head and Neck Squamous Cell Carcinoma: Interactions and Therapeutic Opportunities -- T Cell Co-regulatory Signals and Their Role in Cancer Therapy -- Assessment of Immune Response in Biotherapy Trials and Clinical Endpoints.
Format
e-Book
Location
Online
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ALERT – adverse late effects of cancer treatment. Volume 2, Normal tissue specific sites and systems

https://libcat.nshealth.ca/en/permalink/provcat33418
Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors. --Heidelberg: Springer , c2014.
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The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system different…
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Other Authors
Rubin, Philip
Constine, Louis S
Marks, Lawrence B
Responsibility
Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors
Alternate Title
Adverse late effects of cancer treatment
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xx, 700 pages)
Series
Medical radiology. Radiation oncology
Series Title
Medical radiology (Series)
ISBN
9783540758631 (electronic bk.)
9783540758624
Subjects (MeSH)
Antineoplastic Agents - adverse effects
Radiotherapy - adverse effects
Radiation Injuries
Subjects (LCSH)
Cancer - Treatment - Complications
Neoplasms - therapy - complications
Abstract
The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 2 of this two-volume work comprehensively documents potential late effects in all the normal tissue anatomic sites in the human body. The detection, diagnosis, management and prevention of effects are all considered in detail, and prognostic outcomes are discussed. Radiation risk factors and interactions with chemotherapy effects are clearly presented. The text is accompanied by numerous supportive illustrations and tables.
Contents
Brain and Cranial Nerves -- Spinal Cord and Peripheral Nervous System -- Neuroendocrine Complications of Radiation and Cancer Therapy -- Eye and Orbit -- Radiation-Induced Ototoxicity -- Late Oral Adverse Effects of Cancer Treatments -- Upper Respiratory and Digestive System: Pharynx, Larynx, and Xerostomia -- Thyroid -- Skin Surface, Dermis, and Wound Healing -- Breast Cancer -- Lung -- Heart, Coronary Arteries, Aorta and Great Vessels, Arteries and Veins, Microcirculation -- Esophagus -- Stomach, Small and Large Intestines -- Liver -- Adverse Late Effects of Radiation Treatment in the Pancreas -- Kidney and Ureter -- Urinary Bladder -- Prostate, Seminal Vesicle, Penis, and Urethra -- The Testes -- Ovary, Uterus (Fallopian Tube, Cervix), Vagina, and Vulva -- Radiation Induced Rectal Toxicity -- Musculoskeletal System: Growing Endochondral Bone, Mature Osseous, Muscle (Striated), and Soft Tissue Mesenchyme -- Hematopoietic System -- Late Effects of Hematopoietic Cell Transplantation Including Total Body Irradiation -- Lymph Nodes, Thymus, Spleen, and Lymphatics.
Format
e-Book
Location
Online
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Alternative and complementary therapies for cancer : integrative approaches and discovery of conventional drugs

https://libcat.nshealth.ca/en/permalink/provcat30156
--Boston, MA: Springer Science+Business Media , c2010.
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Location
Online
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Other Authors
Alaoui-Jamali, Moulay
Place of Publication
Boston, MA
Publisher
Springer Science+Business Media
Date of Publication
c2010
ISBN
9781441900203
Subjects (MeSH)
Neoplasms - therapy
Plants, Medicinal
Complementary Therapies
Subjects (LCSH)
Alternative medicine
Oncology
Pharmacy
Format
e-Book
Location
Online
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Atlas of PET-CT Imaging in Oncology : A Case-Based Guide to Image Interpretation

https://libcat.nshealth.ca/en/permalink/provcat39331
Tamer Özülker, Filiz Özülker. --Cham: Springer , c2015.
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Online
This atlas is a case-based guide to the interpretation of FDG PET-CT images in clinical scenarios faced by physicians during the routine practice of oncology. The book aims to help the practitioner to overcome diagnostic dilemmas through familiarization with the physiologic distribution of FDG, normal variants, and benign findings. It includes a rich variety of atypical incidental findings which are rarely seen but may give rise to inconclusive reports. The main focus, however, is the imaging o…
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Author
Özülker, Tamer
Other Authors
Özülker, Filiz
Responsibility
Tamer Özülker, Filiz Özülker
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xxiii, 469 p. : 481 illus., 283 illus. in color)
ISBN
9783319189949
9783319189932 (print ed.)
Subjects (MeSH)
Multimodal Imaging
Neoplasms - diagnosis
Neoplasms - therapy
Positron-Emission Tomography
Tomography, X-Ray Computed
Abstract
This atlas is a case-based guide to the interpretation of FDG PET-CT images in clinical scenarios faced by physicians during the routine practice of oncology. The book aims to help the practitioner to overcome diagnostic dilemmas through familiarization with the physiologic distribution of FDG, normal variants, and benign findings. It includes a rich variety of atypical incidental findings which are rarely seen but may give rise to inconclusive reports. The main focus, however, is the imaging of major oncological diseases, including the rare ones. Different pathologies are addressed in individual chapters comprising teaching files of cases, each of which corresponds to a common indication for PET-CT imaging. These indications include metabolic characterization of lesions, detection of an unknown primary, staging, restaging, and evaluation of response to therapy. Each case is accompanied by a succinct explanation of the patient's history, interpretation of the PET-CT study, and a teaching point which is often supported by relevant literature. This book will be of great value to residents and practitioners in nuclear medicine, radiology, oncology, radiation oncology, and nuclear medicine technology.
Contents
Part I. Fundamentals -- 1 Physiologic Distribution of 18F-FDG -- 2 Normal Variants and Benign Findings -- Part II. PET/CT in Oncology -- 3 Head and Neck Cancer -- 4 Thyroid Cancer -- 5 Lung Cancer -- 6 Breast Cancer -- 7 Lymphoma -- 8 Colorectal Cancer -- 9 Gastric and Esophageal Tumors -- 10 Liver Tumors -- 11 Pancreas -- 12 Gastrointestinal Stromal Tumors -- 13 Surrenal Tumors -- 14 Gynecologic Tumors -- 15 Urologic -- 16 Musculoskeletal Tumors -- 17 Skin Cancers -- 18 Miscellaneous.
Format
e-Book
Publication Type
Atlas
Case Reports
Location
Online
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Atlas of Response to Immunotherapy

https://libcat.nshealth.ca/en/permalink/provcat45029
Egesta Lopci, Stefano Fanti, editors. --Cham: Springer , c2020.
Available Online
View e-Book
Location
Online
This atlas is a concise but comprehensive guide to the diverse patterns of response to immunotherapy as observed on Positron Emission Tomography/Computed Tomography (PET/CT) and other conventional imaging modalities, including CT and Magnetic Resonance Imaging (MRI). The purpose for this publication is to fill the gap between the growing clinical relevance and utilization of immunotherapy in medical oncology, mainly based on checkpoint inhibitors, and the need for experienced imagers with relia…
Available Online
View e-Book
Other Authors
Lopci, Egesta
Fanti, Stefano
Responsibility
Egesta Lopci, Stefano Fanti, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (viii, 127 p.) : 111 illus., 100 illus. in color
ISBN
9783030311131
9783030311124 (Print ed.)
9783030311148 (Print ed.)
9783030311155 (Print ed.)
Subjects (MeSH)
Immunotherapy - methods
Neoplasms - immunology
Neoplasms - therapy
Positron Emission Tomography Computed Tomography
Treatment Outcome
Specialty
Biological Therapy
Medical Oncology
Abstract
This atlas is a concise but comprehensive guide to the diverse patterns of response to immunotherapy as observed on Positron Emission Tomography/Computed Tomography (PET/CT) and other conventional imaging modalities, including CT and Magnetic Resonance Imaging (MRI). The purpose for this publication is to fill the gap between the growing clinical relevance and utilization of immunotherapy in medical oncology, mainly based on checkpoint inhibitors, and the need for experienced imagers with reliable tools assessing response to treatment. A series of disease-oriented chapters will present the imaging findings during immunotherapy in the major oncological settings, with helpful comparison of functional (PET/CT) and morphological (CT/MRI) patterns of response in individual cases. To complete the atlas, a dedicated chapter will focus on major pitfalls and immune-related adverse events (irAEs) affecting image interpretation during the course of immunotherapy. The concluding chapter will lastly examine the available data and potential developments of immuno-PET, which is considered as the novel frontier of research in this oncological scenario. The atlas will be of high value for radiologists and nuclear medicine specialists at all levels of experience.
Contents
Part I. Brief Introduction -- 1. Immunotherapy in Oncology -- 2. Evolution of Response Criteria in Immunotherapy -- Part II. Disease-Oriented Applications -- 3. CNS Tumors: PET/CT and MRI for Response Assessment of CNS Tumors Following Immunotherapy -- 4. Lung Cancer: 18F-FDG PET/CT for Response Assessment of Lung Following Immunotherapy -- 5. Malignant Pleural Mesothelioma: 18F-FDG PET/CT for Response Assessment of Malignant Pleural Mesothelioma Following Immunotherapy -- 6. Melanoma: 18F-FDG PET/CT for Response Assessment of Melanoma Following Immunotherapy -- 7. Genitourinary Tumors: PET/CT for Response Assessment of Genitourinary Tumors Following Immunotherapy -- 8. Hematologic Malignancies: PET/CT for Response Assessment of Hematologic Malignancies Following Immunotherapy -- 9. Other Tumor Types: 18F-FDG PET/CT for Response Assessment of Various Tumors Following Immunotherapy -- Part III. Potential Pitfalls to Response Assessment -- 10. Pitfalls and Immune-Related Adverse Events -- Part IV. New Radiopharmaceuticals -- 11. ImmunoPET: The Future of Response Evaluation for Cancer Immunotherapy.
Format
e-Book
Publication Type
Atlas
Location
Online
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Atlas of Skin Cancers : Practical Guide to Diagnosis and Treatment

https://libcat.nshealth.ca/en/permalink/provcat29729
Ali Hendi, Juan Carlos Martinez. --Heidelberg: Springer , c2011.
Available Online
View e-Book
Location
Online
Available Online
View e-Book
Author
Hendi, Ali
Corporate Author
Mayo Foundation for Medical Education and Research
Other Authors
Martinez, Juan Carlos
Responsibility
Ali Hendi, Juan Carlos Martinez
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2011
Physical Description
1 online resource (xii, 124 p.) : ill.
ISBN
9783642133992
9783642133985 (print ed.)
Subjects (MeSH)
Skin Neoplasms - diagnosis
Skin Neoplasms - therapy
Skin - pathology
Contents
1. Introduction -- 2. Actinic Keratosis -- 3. Nonmelanoma Skin Cancer -- 4. Melanoma -- 5. Miscellaneous Cutaneous Neoplasms -- 6. Biopsy Techniques -- 7. Complications of Skin Cancer Treatment.
Format
e-Book
Publication Type
Atlas
Location
Online
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Atlas of Thyroid and Neuroendocrine Tumor Markers

https://libcat.nshealth.ca/en/permalink/provcat43325
Luca Giovanella, editor. --Cham: Springer , c2018.
Available Online
View e-Book
Location
Online
This book highlights the increase in thyroid tumors and NET and demonstrates the growing importance of circulating markers in diagnosis as well as treatment and follow-up. Dramatic technical improvements have heightened the clinical impact of well-established, conventional biochemical markers. In addition, more recent genetic and molecular approaches have provided innovative molecular markers. In this context, effective communication between clinicians and laboratory physicians/scientists is es…
Available Online
View e-Book
Other Authors
Giovanella, Luca
Responsibility
Luca Giovanella, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xii, 249 p.) : 41 illus., 30 illus. in color
ISBN
9783319625065
9783319625058 (print ed.)
9783319625072 (print ed.)
9783319873305 (print ed.)
Subjects (MeSH)
Biomarkers, Tumor
Neuroendocrine Tumors - diagnosis
Neuroendocrine Tumors - therapy
Thyroid Neoplasms - diagnosis
Thyroid Neoplasms - therapy
Specialty
Endocrinology
Medical Oncology
Abstract
This book highlights the increase in thyroid tumors and NET and demonstrates the growing importance of circulating markers in diagnosis as well as treatment and follow-up. Dramatic technical improvements have heightened the clinical impact of well-established, conventional biochemical markers. In addition, more recent genetic and molecular approaches have provided innovative molecular markers. In this context, effective communication between clinicians and laboratory physicians/scientists is essential in allowing all those involved to fully profit from these exciting advances. In this comprehensive, up-to-date book, authors from different laboratory and clinical areas link laboratory and clinical topics. Analytical problems such as interferences, false-negative and false-positive results are discussed in depth, and flow-charts offer insights into identifying and avoiding them. Illustrated clinical cases detail the clinical role and limitations of different tumor markers. Lastly, it explores health technology assessment and economic issues. This is a valuable resource for endocrinologists, oncologists, nuclear medicine physicians, scientists and technologists who want to keep abreast of the latest developments.
Contents
Part I. Pathology and Pathobiology -- 1. Pathology and Immunohistochemistry in Thyroid Tumors -- 2. Pathology of Neuroendocrine Neoplasms: Morphological, Immunophenotypical, and Circulating Molecular Markers -- 3. Circulating Biomarkers: Biological Basis, Methods, and Interpretation Criteria -- Part II. Differentiated Thyroid Cancer -- 4. Differentiated Thyroid Cancer: Diagnosis, Therapy, and Follow-Up -- 5. Thyroglobulin and Thyroglobulin Antibodies -- 6. Circulating Molecular Biomarkers in Thyroid Cancer -- 7. Circulating Epithelial Tumor Cells in Thyroid Carcinoma -- Part III. Medullary Thyroid Carcinoma -- 8. Medullary Thyroid Carcinoma (MTC): Diagnosis, Treatment and Follow-Up -- 9. Calcitonin and Carcinoembryonic Antigen for the Diagnosis and Management of Medullary Thyroid Carcinoma -- 10. Procalcitonin: Are We Ready for Clinical Use? -- Part IV. Aggressive and Rare Thyroid Carcinoma -- 11. Aggressive Variants of Thyroid Carcinoma -- 12. Circulating Mucins and Cytokeratins in Aggressive Thyroid Cancers -- Part V. Thyroid Biomarkers on Fine-Needle Washouts -- 13. Measurement of Thyroid Tumor Markers on Fine-Needle Washouts -- Part VI. Neuroendocrine Tumors -- 14. Neuroendocrine Tumours: Diagnosis, Therapy and Follow-up -- 15. Circulating Markers in Neuroendocrine Tumors -- 16. Neuroendocrine Gene Transcripts: The Role of Molecular Biomarkers in Diagnosis and Management.
Format
e-Book
Publication Type
Atlas
Location
Online
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Atypical Breast Proliferative Lesions and Benign Breast Disease

https://libcat.nshealth.ca/en/permalink/provcat42749
Farin Amersi, Kristine Calhoun, editors. --Cham: Springer , c2018.
Available Online
View e-Book
Location
Online
The days of surgical excision for any atypical lesion have been replaced by more nuanced decision making and individualized patient management. Current management of many of these lesions continues to be controversial in regard to observation with close surveillance versus the need for surgical excision of these lesions based on future risk or whether these lesions are precursor lesion. The goal of this book is to provide a concise but comprehensive review of atypical breast proliferative lesio…
Available Online
View e-Book
Other Authors
Amersi, Farin
Calhoun, Kristine
Responsibility
Farin Amersi, Kristine Calhoun, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xi, 197 p.) : 28 illus., 24 illus. in color
ISBN
9783319926575
9783319926568 (print ed.)
9783319926582 (print ed.)
Subjects (MeSH)
Breast Diseases - therapy
Breast Neoplasms - therapy
Specialty
Gynecology
Medical Oncology
Abstract
The days of surgical excision for any atypical lesion have been replaced by more nuanced decision making and individualized patient management. Current management of many of these lesions continues to be controversial in regard to observation with close surveillance versus the need for surgical excision of these lesions based on future risk or whether these lesions are precursor lesion. The goal of this book is to provide a concise but comprehensive review of atypical breast proliferative lesions and their management complexities. New data about breast cancer, risk factors for breast cancer, pathological features unique to each entity, the characteristic findings on imaging, risk stratification for genetic testing, as well as the current evidence-based management of each of these breast lesions are discussed in full detail. Assessment tools for risk prediction of breast cancer are also highlighted as chapters run the gamut of current imaging modalities, as well as advanced screening options available for diagnosis and following these patients. Atypical Breast Proliferative Lesions and Benign Breast Disease will undoubtedly become a valuable resource for nurse practitioners, physician assistants, breast and surgical oncology fellows, genetic counselors, geneticists, as well as other clinicians and surgeons who are referred and manage these complex breast patients. All chapters in this text are written by experts in the field who have research and clinical interest in each of these disease entities, and include the most up-to-date research and clinical information to enhance our understanding and treatment of patients.
Contents
The Spectrum of Risk Lesions in Breast Pathology: Risk Factors or Cancer Precursors? -- Lobular Carcinoma In Situ: Risk Factor or Cancer Precursor? -- Ductal Carcinoma In Situ: Risk Factor or Cancer -- Diagnostic Management of Papillomas, Radial Scars, and Flat Epithelial Atypia: Core Biopsy Alone Versus Core Biopsy Plus Excision -- Diagnostic Management of Fibroepithelial Lesions: When Is Excision Indicated? -- Diagnostic Management of the Atypical Hyperplasias: Core Biopsy Alone vs Excisional Biopsy -- Diagnostic management of LCIS: Core biopsy alone versus core biopsy plus excision for classic versus pleomorphic LCIS -- Breast Cancer Risk Prediction in Women with Atypical Breast Lesions -- Advanced Screening Options and Surveillance in Women with Atypical Breast Lesions -- The Role of Chemoprevention in the Prevention of Breast Cancer -- Prophylactic Mastectomy in Patients with Atypical Breast Lesions -- The Non-surgical Management of Ductal Carcinoma in Situ (DCIS) -- Surgical Treatment of Ductal Carcinoma in Situ.
Format
e-Book
Location
Online
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Benign Tumors of the Liver

https://libcat.nshealth.ca/en/permalink/provcat39151
Luca Aldrighetti, Francesco Cetta, Gianfranco Ferla, editors. --Cham: Springer , c2015.
Available Online
View e-Book
Location
Online
Diagnosis of benign tumors of the liver is experiencing exponential growth, mainly owing to the diffusion of more accurate imaging techniques. This monograph opens by examining the epidemiology, histopathology, and genetics of these diseases and discussing liver physiopathology. The role of imaging techniques is described, and clear guidance provided on differential diagnosis. The full range of benign liver tumors and conditions is then systematically reviewed, including liver cysts and polycys…
Available Online
View e-Book
Other Authors
Aldrighetti, Luca
Cetta, Francesco
Ferla, Gianfranco
Responsibility
Luca Aldrighetti, Francesco Cetta, Gianfranco Ferla, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xvi, 337 p. : 110 illus., 57 illus. in color)
ISBN
9783319129853
9783319129846 (print ed.)
Subjects (MeSH)
Liver Neoplasms - diagnosis
Liver Neoplasms - therapy
Liver - physiopathology
Abstract
Diagnosis of benign tumors of the liver is experiencing exponential growth, mainly owing to the diffusion of more accurate imaging techniques. This monograph opens by examining the epidemiology, histopathology, and genetics of these diseases and discussing liver physiopathology. The role of imaging techniques is described, and clear guidance provided on differential diagnosis. The full range of benign liver tumors and conditions is then systematically reviewed, including liver cysts and polycystic liver disease, Caroli disease, hemangiomas, focal nodular hyperplasia, adenomas, hepatic manifestations of systemic diseases, and focal infectious diseases. Surgical indications are accurately analyzed, with a view to assisting in the avoidance of useless interventions. Transplantation, laparoscopic resection, and robotic surgical techniques are described and illustrated, emphasizing the optimization of intra- and postoperative management in order to avoid potential complications and degeneration. In these chapters, attention is drawn to the ways in which the surgical management of benign liver tumors differs from that of malignant tumors. Information is also provided on anesthesia, blood transfusion, the role of interventional radiology in patients with benign liver tumors and fast track programs for liver surgery. This book, in handy format, will prove essential reading for all who are interested in benign liver surgery and will represent an invaluable source of knowledge for general and hepatobiliary surgeons, whether in training or practice.
Contents
Foreword -- Preface -- Part I: General Perspective -- 1. Epidemiology and Histopathology of Benign Liver Tumors -- 2. Molecular Biology and Genetics of Benign Liver Tumors -- 3. Genetic Syndromes and Benign Liver Tumors (Multiple Adenomas in Glycogen Storage Disease) -- 4. Liver Physiopathology (Ischemia/Reperfusion, Factors affecting Liver Regeneration) -- Part II: Imaging -- 5. Imaging Techniques (Ultrasound, CT, MR) of Benign Liver Tumors -- 6. Imaging Morphology in Benign Liver Tumors -- 7. Differential Diagnosis of Benign Liver Tumors -- Part III: Systematic Review of Benign Liver Tumors -- 8. Cysts and Polycystic Liver Disease -- 9. Caroli's Disease: Cystic Bile Duct Dilatations -- 10.Hepatolithiasis -- 11. Hemangiomas -- 12. Focal Nodular Hyperplasia -- 13. Hepatocellular Adenoma -- 14. Adenoma and Biliary Cystadenoma -- 15.Benign Tumors of Bile Ducts and Gallbladder -- 16. Liver Focal Localizations of Systemic Diseases -- 17. Focal Infectious Diseases -- Part IV: Treatment of Benign Liver Tumors -- 18. Transplantation for Benign Liver Lesions -- 19. Laparoscopic Liver Surgery in Benign Liver Lesions -- 20. Robotic Liver Resection for Benign Tumors -- 21. Interventional Radiology in Benign Liver Tumors: Embolization and Ablation -- 22. Intraoperative Ultrasound in Liver Surgery for Benign Tumors -- 23. Anesthesia and Intraoperative Management in Liver Surgery -- 24. Blood and Transfusion Management in Benign Liver Tumors -- 25. Fast Track Programs in Benign Liver Tumors.
Format
e-Book
Location
Online
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Bethesda handbook of clinical oncology

https://libcat.nshealth.ca/en/permalink/provcat23054
Abraham, Jame. (2nd ed.) --Philadelphia, PA: Lippincott Williams & Wilkins , 2005.
Call Number
QZ 266 B562 2005
Location
Dickson Building
Call Number
QZ 266 B562 2005
Author
Abraham, Jame
Other Authors
Allegra, Carmen J
Gulley, James
Edition
2nd ed.
Place of Publication
Philadelphia, PA
Publisher
Lippincott Williams & Wilkins
Date of Publication
2005
Physical Description
687 p.
ISBN
0781751160
Subjects (MeSH)
Neoplasms - therapy - Handbooks
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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