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NAFLD and NASH : Biomarkers in Detection, Diagnosis and Monitoring

https://libcat.nshealth.ca/en/permalink/provcat45509
Manuel Romero-Gomez, editor. --Cham: Springer , c2020.
Available Online
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Location
Online
This book provides a comprehensive overview of the diagnosis and management of Non-alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatis (NASH). Basic principles of disease progression, the genetic and nutritional basis of NAFLD and NASH are explained along with the proteomic principles underlying biomarker development. Chapters cover both biochemical and imaging biomarkers used in elastrography and ultrasound and discuss how these are applicable to early diagnosis and monitorin…
Available Online
View e-Book
Other Authors
Romero-Gomez, Manuel
Responsibility
Manuel Romero-Gomez, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (x, 236 p.) : 18 illus., 17 illus. in color
ISBN
9783030371739
9783030371722 (Print ed.)
9783030371746 (Print ed.)
9783030371753 (Print ed.)
Subjects (MeSH)
Biomarkers - analysis
Diagnostic Techniques and Procedures
Fatty Liver - diagnosis
Non-alcoholic Fatty Liver Disease - diagnosis
Specialty
Diagnosis
Gastroenterology
Molecular Medicine
Abstract
This book provides a comprehensive overview of the diagnosis and management of Non-alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatis (NASH). Basic principles of disease progression, the genetic and nutritional basis of NAFLD and NASH are explained along with the proteomic principles underlying biomarker development. Chapters cover both biochemical and imaging biomarkers used in elastrography and ultrasound and discuss how these are applicable to early diagnosis and monitoring of NASH and NAFLD. This is a useful resource for hepatologists, primary care providers with an interest in metabolic disease, diabetologists and endocrinologists in their daily clinical practice.
Contents
1. The Spectrum of NAFLD: From the Organ to the System -- 2. Detection of NAFLD/NASH in the General Population and in Primary Care Clinics -- 3. Genes and NAFLD/NASH Progression -- 4. Geometry of Nutrition: Nutrients and NAFLD Progression -- 5. Biomarkers in Pediatric NAFLD -- 6. Biochemical Biomarkers of NAFLD/NASH -- 7. Non-invasive Assessment of Non-alcoholic Fatty Liver Disease: Ultrasound and Transient Elastography -- 8. MR Based-Imaging Biomarkers in NAFLD/NASH -- 9. Extracellular Vesicles in Non-alcoholic Fatty Liver Disease: Key Players in Disease Pathogenesis and Promising Biomarker Tools -- 10. From Transcriptomic to Metabolomic in the Development of Biomarkers in NAFLD/NASH -- 11. HCC in Patients with NAFLD/NASH -- 12. Psychological Biomarker Profile in NAFLD/NASH with Advanced Fibrosis -- 13. Integrative Proposal for the Use of Biomarkers in Clinical Practice Management of NAFLD/NASH.
Format
e-Book
Location
Online
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