Adipocytokines provide the circuitry by which adipose tissue communicates among its component cells which include adipocytes, stromal cells, immune cells and vascular elements, with adipose tissue depots in other locations throughout the body and with other tissues in order to regulate physiologic processes of energy intake, utilization, and distribution. Since disturbances, both qualitative and quantitative, in adipocytokine function contribute significantly to many of the comorbidities associ…
The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous…
Presenting detailed information on treatment of the obese patient, this handy, concise title is designed not only to educate practitioners about obesity but, most importantly, to provide practical strategies in the comprehensive approach to treating this disease. Replete with bulleted lists and tables for easy referencing, this unique reference provides a comprehensive overview of the pathophysiology and natural history of obesity as well as a thorough review of available treatment options. The…
This book provides an up to date review on antimicrobials dosing in obese patients, including practice recommendations for clinical use. The book is written by a group of doctors and pharmacists working in infectious diseases practice and research. The introductory chapter outlines the important physiological changes in obesity including factors affecting the dosing of antimicrobials in obese patients. The introductory chapter is followed by ten chapters covering the major classes of antibiotic…
The obesity pandemic continues to increase on a world-wide basis with over 70% of the United States population being either overweight or obese. Hematologic malignancies have recently been identified among the obesity associated malignancies spanning the lifespan from childhood to the elderly and include leukemia, myeloma, lymphoma and others. In addition to the potential etiologic association between obesity and hematologic malignancies, the presence of obesity has profound effects on therapy …
This volume provides a comprehensive treatise on the latest studies linking prostate cancer with energy balance, which together constitute a major challenge and opportunity for research scientists and clinicians especially those dealing with the expanding population of older men confronted with obesity and associated comorbidities. This volume should be a valuable resource to physicians, oncologists, urologists, endocrinologists, nurses, nutritionists, dieticians, and exercise therapists dealin…
Gynecologic malignancies, especially endometrial and ovarian cancers are among the most important and most severely affected by obesity. This volume of Energy Balance and Cancer, written by the world's leading experts in this field, is arranged to provide a transdisciplinary assessment of the pertinent issues, results of relevant research on mechanisms, and control, strategies for dealing with affected patients and improving outcomes and future research needs. The volume comprehensively covers …
The increasing prevalence of morbid obesity has led the World Health Organization to coin the descriptive term "globesity" to reflect the worldwide nature of the problem. Providing health care to these patients, especially when surgery is required, can be extremely challenging owing to the specific needs in respect of logistics, facilities, and professional expertise. Appropriate care has too often been unachievable and unaffordable outside of established bariatric centers, but such centers the…
This volume reviews disparities in cancer genetics, etiology, treatment and survivorship that are associated with differences in energy balance and how those differences and disparities may be affected by geography, socioeconomic status, ethnicity, biology, behavior and others. State-of-the-art strategies are outlined to alter these problems at the individual, community and policy levels. The book provides a comprehensive assessment of the multiple contributions of disparities in energy balance…
This book is the first to describe a practical evidence-based approach to the management of critically ill obese patients with various medical or postoperative respiratory problems in the intensive care unit. In brief, the book aims to identify the best strategy and present clinical recommendations for different circumstances, to establish indications for and contraindications to noninvasive and invasive mechanical ventilation, and to offer clear guidance on weaning from mechanical ventilation …
This volume provides a transdisciplinary and translational review of many of the leading murine models used to study the mechanisms, mediators and biomarkers linking energy balance to cancer. It provides a review of murine models that should be of interest to basic, clinical and applied research investigators as well as nutrition scientists and students that work in cancer prevention, cancer control and treatment. The worldwide obesity pandemic has been extensively studied by epidemiologic and …
This book provides a comprehensive and up-to-date review of the relationship between obesity and cancer. It opens with a global perspective on obesity and cancer incidence, followed by in-depth discussions of those cancers for which we have sufficient evidence of a causal relationship with obesity. It addresses topics such as the effects of obesity on cancer incidence and cancer survival, the effects of weight gain and weight loss in adulthood on cancer risk, the effects of childhood and adoles…
This timely and clinically oriented book uniquely addresses the entire spectrum of treatment for severe obesity and diabetes. It thoroughly examines all aspects from robotic surgery to cell therapy, from the latest antidiabetic drugs to endoscopic procedures and devices, from appetite-inhibiting signals and nutrients to gastric arterial embolization. It offers objective and authoritative information for practicing professionals; not only are successful interventions discussed and updated, but c…