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60 years of survival outcomes at the University of Texas MD Anderson Cancer Center

https://libcat.nshealth.ca/en/permalink/provcat32423
M. Alma Rodriguez, Ronald S. Walters, Thomas W. Burke, editors. --New York, NY: Springer , c2013.
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This unique book provides a retrospective analysis of the changes in survival outcomes at The University of Texas M.D. Anderson Cancer Center over the past six decades. Since opening its doors in 1944, M.D. Anderson has kept a continuous, uninterrupted data repository of the treatment and outcomes of each of its patients. It is this visionary database from the Center's tumor registry which makes this groundbreaking book possible. Tracking results across time, the book shows radical shifts in ou…
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Rodriguez, M. Alma
Walters, Ronald S
Burke, Thomas W
Responsibility
M. Alma Rodriguez, Ronald S. Walters, Thomas W. Burke, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xiii, 346 p. : 124 ill. in color)
ISBN
9781461451976
Subjects (MeSH)
Academies and Institutes - history
History, 20th century
History, 21st century
Neoplasms - epidemiology
Neoplasms - therapy
Registries
Survival Analysis
Texas - epidemiology
Treatment Outcome
Subjects (LCSH)
Oncology
Epidemiology
Abstract
This unique book provides a retrospective analysis of the changes in survival outcomes at The University of Texas M.D. Anderson Cancer Center over the past six decades. Since opening its doors in 1944, M.D. Anderson has kept a continuous, uninterrupted data repository of the treatment and outcomes of each of its patients. It is this visionary database from the Center's tumor registry which makes this groundbreaking book possible. Tracking results across time, the book shows radical shifts in outcomes trends, where great progress has been made, and where there is still a long way to go, and offers a snapshot of the parallel history of developments in care. Such data is crucial to informing how patients are counseled, how treatment decisions are determined, and how prognoses are made. 60 Years of Survival Outcomes at The University of Texas M.D. Anderson Cancer Center is the only book to concurrently present longitudinal data on survival outcomes across the spectrum of rare and common cancers. Each chapter deals with a specific disease site, discussing current management approaches and presenting key data replete with illustrative charts, graphs, and tables. With the resources available only to the practitioners at this inimitable institution, this book heralds a cornerstone moment in the study of survival outcomes and the depth of our knowledge of cancer care.
Contents
Ch. 1:Introduction -- Ch. 2:History of MD Anderson's Tumor Registry -- Ch. 3:Statistical Methods -- Ch. 4:Breast Cancer -- Ch. 5:Prostate Cancer -- Ch. 6:Non-Small Cell Lung Cancer -- Ch. 7:Small Cell Lung Cancer -- Ch. 8:Colon Cancer -- Ch. 9:Ovarian Cancer -- Ch. 10:Cervical Cancer -- Ch. 11:Endometrial Cancer -- Ch. 12:Pancreatic Cancer (Exocrine) -- Ch. 13:Kidney Cancer -- Ch. 14:Bladder Cancer -- Ch. 15:Cutaneous Melanoma -- Ch. 16:Liver Cancer -- Ch. 17:Esophageal Cancer -- Ch. 18:Gastric Cancer -- Ch. 19:Acute Myeloid Leukemia -- Ch. 20:Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma -- Ch. 21:Hodgkin Lymphoma -- Ch. 22:Non-Hodgkin Indolent B-Cell Lymphoma -- Ch. 23:Non-Hodgkin Aggressive B-Cell Lymphoma -- Ch. 24:Multiple Myeloma -- Ch. 25:Head and Neck Cancer -- Ch. 26:Thyroid Cancer -- Ch. 27:Soft Tissue Sarcomas -- Ch. 28:Sarcomas of Bone -- Index.
Format
e-Book
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Online
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Abdominal Neuroendocrine Tumors

https://libcat.nshealth.ca/en/permalink/provcat43267
Massimo Carlini, editor. --Milano: Springer , c2018.
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This book aims to equip readers with a better understanding of neuroendocrine tumors of the abdomen and explains how to manage them optimally by making use of novel therapeutic options that represent major advances on previous treatments. The most recent advances in epidemiology, genetics, molecular biology, biomarkers, pathology, diagnostics, clinical assessment, medical therapy, and surgical treatment are presented. The information and data provided will stimulate readers to develop their per…
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Carlini, Massimo
Responsibility
Massimo Carlini, editor
Place of Publication
Milano
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xvii, 198 p.) : 20 illus., 10 illus. in color
Series Title
Updates in surgery
ISBN
9788847039551
9788847039544 (print ed.)
9788847039568 (print ed.)
9788847039711 (print ed.)
ISSN
2280-9848
Subjects (MeSH)
Abdominal Neoplasms
Neuroendocrine Tumors
Specialty
Endocrinology
Neurology
Medical Oncology
Abstract
This book aims to equip readers with a better understanding of neuroendocrine tumors of the abdomen and explains how to manage them optimally by making use of novel therapeutic options that represent major advances on previous treatments. The most recent advances in epidemiology, genetics, molecular biology, biomarkers, pathology, diagnostics, clinical assessment, medical therapy, and surgical treatment are presented. The information and data provided will stimulate readers to develop their personal opinions on significant issues and assist in decision making in individual patients during routine clinical practice. The book features a multidisciplinary approach and is designed to meet the needs of all physicians seeking comprehensive guidance from experts on the management of patients with neuroendocrine tumors. It will also be of value for researchers wishing to acquaint themselves with the state of the art in the field and emerging research avenues. Abdominal Neuroendocrine Tumors is published in Springer's highly successful Updates in Surgery series, which now comprises more than 20 titles.
Contents
Part I. Nosography -- 1. Neuroendocrine Tumors: a Nosologic Framework -- 2. Classification of Abdominal Neuroendocrine Tumors -- 3. Hereditary Syndromes and Abdominal Neuroendocrine Tumors -- 4. Sporadic Gastroenteropancreatic Neuroendocrine Tumors -- Part II. Diagnosis -- 5. Neuroendocrine Tumors Biomarkers -- 6. Endoscopic Diagnosis of Gastrointestinal and Pancreatic Neuroendocrine Tumors -- 7. Role of Non-Functional Imaging in the Diagnosis of Abdominal Neuroendocrine Tumors -- 8. Role of Functional Imaging in the Diagnosis of Neuroendocrine Tumors -- 9. Pathological Analysis of Abdominal Neuroendocrine Tumors -- Part III. Management -- 10. Management of Gastric Neuroendocrine Tumors -- 11. Management of Pancreatic and Duodenal Neuroendocrine Tumors -- 12. Management of Ileal, Appendiceal and Colorectal Neuroendocrine Tumors -- 13. Management of Liver Metastases from Gastroenteropancreatic Neuroendocrine Tumors.
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e-Book
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Abeloff's clinical oncology

https://libcat.nshealth.ca/en/permalink/provcat43446
Niederhuber, John. (5th ed.) --Philadelphia, PA: Elsevier Saunders , 2014.
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Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
Location
Online
Author
Niederhuber, John
Edition
5th ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Date of Publication
2014
Physical Description
online resource
ISBN
9781455728657
Subjects (MeSH)
Neoplasms - therapy
Medical Oncology - methods
Access
Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
Format
e-Book
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Abeloff's clinical oncology

https://libcat.nshealth.ca/en/permalink/provcat32179
[edited by] John E. Niederhuber, James O. Armitage, Michael B. Kastan ...[et al.]. (6th ed.) --Philadelphia, PA: Elsevier , c2020.
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Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment…
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Niederhuber, John E.
Responsibility
[edited by] John E. Niederhuber, James O. Armitage, Michael B. Kastan ...[et al.]
Edition
6th ed.
Alternate Title
Clinical oncology
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
c2020
Physical Description
1 online resource, 2072 p.
ISBN
9780323476744
Subjects (MeSH)
Neoplasms - therapy
Medical Oncology - methods
Subjects (LCSH)
Oncology
Cancer--Treatment
Specialty
Medical Oncology
Abstract
Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up.
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Format
e-Book
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Absolute Clinical Radiation Oncology Review

https://libcat.nshealth.ca/en/permalink/provcat44248
Daniel M. Trifiletti, Nicholas G. Zaorsky, editors. --Cham: Springer , 2019.
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This book provides a quick reference guide for clinicians in radiation oncology. It is designed to be an intuitive and easily reviewed study guide for board or maintenance of certification examinations, as well as a quick reference for residents and established radiation oncologists who need a refresher. The text begins with a general pearls chapter that radiation oncologists should consider in all aspects of their practice, including cancer visibility, dosing, counseling recommendations, and t…
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Other Authors
Trifiletti, Daniel M.
Zaorsky, Nicholas G.
Responsibility
Daniel M. Trifiletti, Nicholas G. Zaorsky, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (xvii, 492 p.) : 191 illus., 178 illus. in color
ISBN
9783319968094
9783319968087 (Print ed.)
9783319968100 (Print ed.)
Subjects (MeSH)
Neoplasms - radiotherapy
Radiation Oncology
Specialty
Medical Oncology
Radiotherapy
Abstract
This book provides a quick reference guide for clinicians in radiation oncology. It is designed to be an intuitive and easily reviewed study guide for board or maintenance of certification examinations, as well as a quick reference for residents and established radiation oncologists who need a refresher. The text begins with a general pearls chapter that radiation oncologists should consider in all aspects of their practice, including cancer visibility, dosing, counseling recommendations, and toxicity management. The subsequent chapters then delve into different cancer disease sites, including pediatrics, central nervous system, head and neck, thoracic, breast, gastrointestinal, gynecologic, genitourinary, hematologic, soft tissue, palliative, and radiophysics/radiobiology. Within each chapter, each disease and its recommended approach is then summarized in only a few pages, allowing a focus on the most essential information. Bullet points, figures, tables, and images make for an intuitive reader experience. The text includes the 7th and 8th editions staging from the American Joint Committee on Cancer (AJCC). Recommendations are taken from the American Society for Radiation Oncology (ASTRO), the European Society for Radiation Oncology (ESTRO), and the National Comprehensive Cancer Network (NCCN). Planning guides for imaging, diagnosis, and staging offer readers a starting point in approaching each patient based on disease origin, and dosing guidelines then detail consideration for treatment methods. Each chapter additionally includes disease-specific pearls and key points to test the knowledge reviewed in the chapters. Experts in the disease sites from the United States serve as senior authors on each chapter. The authors include all diseases associated with radiation oncology training to ensure a comprehensive resource for exam studying and clinical care. Residents, trainees, and established radiation oncologists find this an ideal study resource for both board and certification exams, as well as an easily accessible aid during practice.
Contents
1. General Principles of Radiation Oncology -- 2. Pediatrics Cancers - 3. Central Nervous System Cancers -- 4. Head and Neck Cancers -- 5. Lung Cancer -- 6. Breast Cancer -- 7. Gastrointestinal Cancers -- 8. Genitourinary Cancers -- 9. Gynecologic Cancers -- 10. Hematologic Cancers -- 11. Soft Tissue Cancers -- 12. Bone/Spine Cancers -- 13. Physics and Radiobiology.
Format
e-Book
Publication Type
Outline
Location
Online
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Accelerated Partial Breast Irradiation : Techniques and Clinical Implementation

https://libcat.nshealth.ca/en/permalink/provcat28378
edited by David E. Wazer, Douglas W. Arthur, Frank A. Vicini. (2nd ed.) --Berlin, Heidelberg: Springer , c2009.
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Online
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Author
Wazer, David E
Other Authors
Arthur, Douglas W
Vicini, Frank A
Responsibility
edited by David E. Wazer, Douglas W. Arthur, Frank A. Vicini
Edition
2nd ed.
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2009
ISBN
9783540880066
Subjects (MeSH)
Breast Neoplasms - radiotherapy
Radiotherapy, Conformal - methods
Subjects (LCSH)
Radiotherapy
Oncology
Gynecology
Format
e-Book
Location
Online
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Acquired Cystic Disease of the Kidney and Renal Cell Carcinoma : Complications of Long-Term Dialysis

https://libcat.nshealth.ca/en/permalink/provcat28396
by Isao Ishikawa. --Tokyo: Springer , c2007.
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Online
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Author
Ishikawa, Isao
Responsibility
by Isao Ishikawa
Place of Publication
Tokyo
Publisher
Springer
Date of Publication
c2007
ISBN
9784431694816
Subjects (MeSH)
Carcinoma, Renal Cell
Kidney Diseases, Cystic
Renal Dialysis - adverse effects
Subjects (LCSH)
Nephrology
Oncology
Format
e-Book
Location
Online
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Active Surveillance for Localized Prostate Cancer : A New Paradigm for Clinical Management

https://libcat.nshealth.ca/en/permalink/provcat43371
Laurence Klotz, editor. (Second edition) --Cham: Humana Press , c2018.
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This fully updated and revised new edition provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in prostate cancer. The book reviews new data about molecular characteristics of the disease, profiles the new grading system for prostate cancer introduced in 2015, and provides new perspectives about imaging of prostate cancer, as well as the role of targeted biopsies. The text summarizes the…
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Other Authors
Klotz, Laurence
Responsibility
Laurence Klotz, editor
Edition
Second edition
Place of Publication
Cham
Publisher
Humana Press
Date of Publication
c2018
Physical Description
1 online resource (xii, 250 p.) : 39 illus., 27 illus. in color
Series Title
Current clinical urology
ISBN
9783319627106
9783319627090 (print ed.)
9783319627113 (print ed.)
9783319873756 (print ed.)
ISSN
2197-7194
Subjects (MeSH)
Disease Progression
Medical Overuse - prevention & control
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - therapy
Watchful Waiting
Specialty
Medical Oncology
Urology
Abstract
This fully updated and revised new edition provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in prostate cancer. The book reviews new data about molecular characteristics of the disease, profiles the new grading system for prostate cancer introduced in 2015, and provides new perspectives about imaging of prostate cancer, as well as the role of targeted biopsies. The text summarizes the role of biomarkers and MRI in patient selection and management and details the world wide results of active surveillance. Specific chapters address communication and ethical issues, QOL outcomes, economic aspects, and psycho-social aspects of surveillance. The role of focal therapy for low risk disease is summarized, and the data supporting preventive interventions during surveillance reviewed. This text will serve as a very useful resource for physicians and researchers dealing with, and interested in this common malignancy, as it provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.
Contents
Cancer Overdiagnosis and Overtreatment -- Can We Screen and Still Reduce Overdiagnosis? -- The Role of Fear in Overdiagnosis and Overtreatment -- Ethical and Legal Considerations in Active Surveillance for Prostate Cancer -- Gleason 6 Tumors Should Still Be Labeled As Cancer -- Risk Based Selection for Active Surveillance -- Surveillance at the Margins: Management of High Volume Gleason 6, PSA>10, or Gleason 3+4 -- How Should Patients on Active Surveillance be Followed? -- Triggers for Intervention -- MR Imaging in Prostate Tumor Volume Assessment: How Accurate? -- Can MRI Replace Biopsy in Men on Surveillance? -- Tissue Based Markers for Risk Prediction -- International AS Registry: The Movember Foundation's Global Action Plan Prostate Cancer Active Surveillance Initiative -- Better Informed Decision Making to Optimize Patient Selection -- How Does QOL Compare Between Surveillance and Active Treatment? -- The Potential Benefits of Diet and Physical Activity among Active Surveillance Patients with Low-Burden Prostate Cancer -- Is there a Role for Pharmacologic Manipulation to Prevent Progression in Men on Active Surveillance? The Role of 5-ARIs, Statins, and Metformin -- The Update of Active Surveillance around the World: Utilization and Outcomes -- Tissue Preservation: Active Surveillance and Focal Therapy as Complimentary Strategies -- The Economics of Active Surveillance for Prostate Cancer -- Research Questions in Active Surveillance.
Format
e-Book
Location
Online
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Active Surveillance for Localized Prostate Cancer : A New Paradigm for Clinical Management

https://libcat.nshealth.ca/en/permalink/provcat31028
Laurence Klotz, editor. --New York, NY: Humana Press , c2012.
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Active Surveillance for Localized Prostate Cancer: A New Paradigm for Clinical Management will serve as a useful resource for physicians dealing with, and interested in, this complex and evolving branch of prostate cancer management. The book will also be of interest to scientifically literate patients and their families. The volume provides an introduction to the concept of active surveillance in oncology in general and prostate cancer specifically. The primary focus is to provide a comprehens…
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Other Authors
Klotz, Laurence
Responsibility
Laurence Klotz, editor
Place of Publication
New York, NY
Publisher
Humana Press
Date of Publication
c2012
Physical Description
1 online resource (xi, 208 p. : 33 ill., 22 ill. in color)
Series Title
Current clinical urology
ISBN
9781617799129
Subjects (MeSH)
Disease Progression
Early Diagnosis
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - therapy
Watchful Waiting
Subjects (LCSH)
Oncology
Urology
Abstract
Active Surveillance for Localized Prostate Cancer: A New Paradigm for Clinical Management will serve as a useful resource for physicians dealing with, and interested in, this complex and evolving branch of prostate cancer management. The book will also be of interest to scientifically literate patients and their families. The volume provides an introduction to the concept of active surveillance in oncology in general and prostate cancer specifically. The primary focus is to provide a comprehensive guide to the management of patients on surveillance. The volume covers the many complexities and nuances to this approach including, patient selection, risk assessment, how to overcome 'cancer hysteria' when counseling patients, identifying appropriate triggers for intervention, use of PSA kinetics and MR imaging information, technique and frequency of biopsies, secondary prevention interventions, and the relative roles of surveillance and focal therapy.
Contents
1. The Problem of Cancer Overdiagnosis and Overtreatment -- 2. Patient Selection for Active Surveillance -- 3. Predicting High Risk Disease Using Tissue Biomarkers -- 4. Predicting High Risk Disease Using Serum and DNA Biomarkers -- 5. Triggers for Intervention in Men on Surveillance -- 6. The Role of MRI in Active Surveillance -- 7. Active Surveillance: The European Experience -- 8. Active Surveillance: The Canadian Experience -- 9. Psychosocial Aspects of Active Surveillance -- 10. Statistical Considerations for Patient Selection and Triggers for Intervention in Active Surveillance -- 11. Interpreting PSA Kinetics using GLMM Technique -- 12. The Potential Benefits of Diet and Physical Activity among Active Surveillance Patients with Low-Burden Prostate Cancer -- 13. The Role of 5[alpha]-Reductase Inhibitors (5-ARIs) in Expectant Management of Low Risk Prostate Cancer -- 14. Urologists' Opinion on Active Surveillance: United States vs. the Netherlands -- 15. Clinical "Pearls" in Managing Patients on Surveillance -- 16. Active Surveillance, Focal Therapy and the Future -- 17. The Economics of Active Surveillance for Prostate Cancer -- 18. The Future of Active Surveillance.
Format
e-Book
Location
Online
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Acupuncture and Moxibustion as an Evidence-based Therapy for Cancer

https://libcat.nshealth.ca/en/permalink/provcat31284
William C.S. Cho, editor. --Dordrecht: Springer , c2012.
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Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments' side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in narrowing the knowledge…
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Other Authors
Cho, William C.S.
Responsibility
William C.S. Cho, editor
Place of Publication
Dordrecht
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xi, 354 p. : 25 ill., 18 ill. in color)
Series Vol.
v. 3
Series Title
Evidence-based anticancer complementary and alternative medicine
ISBN
9789400748330
Subjects (MeSH)
Acupuncture Therapy
Evidence-Based Medicine
Moxibustion
Neoplasms - therapy
Subjects (LCSH)
Oncology
Alternative medicine
Acupuncture
Abstract
Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments' side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in narrowing the knowledge gap to explore the scientific and evidence-based knowledge of CAM in the anticancer field. With this aim, an unparalleled undertaking of a book series is launched to structurally consolidate this area. Although acupuncture and moxibustion have been practiced for millennia, they have come under scientific investigation only recently. Acupuncture and moxibustion have been used clinically to treat cancer-related symptoms (e.g. cancer pain, anxiety, depression and insomnia), manage treatment-induced side effects (e.g. hot flashes, nausea and vomiting) and enhance immunity (e.g. blood cell count, lymphocyte and natural killer cell activity). This is the first book manages to provide comprehensive and updated scientific evidence of the effectiveness of acupuncture and moxibustion intervention for cancer care. Laboratory and animal studies have uncovered the mechanisms of acupuncture and moxibustion for cancer therapy. Promising results of most clinical trials show the efficacy and safety of acupuncture and moxibustion in cancer management. This book consists of fifteen chapters which address a range of important aspects that will impact on the application of acupuncture and moxibustion. An overview of the safety and side effects of acupuncture and moxibustion for cancer care are also covered. In addition, the integration of acupuncture with Western medicine in cancer treatment and recent clinical trials are included as well. Opinion leaders around the world have teamed up to pursue a thorough and up-to-date review of the area, this volume will contribute great to the cancer, clinical and academic community by providing evidence-based information on the efficacy of acupuncture and moxibustion as an anticancer therapy.
Contents
Prelims -- 1. An Overview of Acupuncture and Moxibustion for Cancer Care -- 2. The Mechanistic Studies of Acupuncture and Moxibustion -- 3. Acupuncture for Cancer Pain -- 4. Acupuncture for the Treatment of Hot Flashes in Cancer Patients -- 5. Acupuncture and Moxibustion for Cancer-related Symptoms -- 6. Use of Acupuncture and Moxibustion in the Control of Anticancer Therapy-induced Nausea and Vomiting -- 7. Acupuncture and Moxibustion for Side Effects of Chemotherapy in Cancer Patients -- 8. Acupuncture for the Treatment of Symptoms Associated with Radiation Therapy -- 9. Quality of Life of Cancer Patients after Acupuncture and Moxibution Treatment -- 10. Acupuncture and Moxibustion for Palliative and Supportive Cancer Care -- 11. Is Acupuncture or Moxibustion Better Than a Sham or Placebo-treatment?-12. Safety and Side Effects of Acupuncture and Moxibustion as a Therapy for Cancer -- 13. Acupuncture and Moxibustion in Animal Models of Cancer -- 14. Integrating Acupuncture with Western Medicine in Cancer Treatment -- 15. Recent Clinical Trials of Acupuncture for Cancer Patients. Index.
Format
e-Book
Location
Online
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Stefan H. Faderl, Hagop M. Kantarjian, Elihu Estey, editors. (Second edition) --Cham: Springer , c2021.
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NEW Springer 2021
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The new edition of this well-received book provides a timely update of current knowledge on the biology, disease classification, and treatment of the acute leukemias – acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Throughout, the focus is on the provision of state of the art information and guidance that will meet the needs of clinicians. Chapters have been extensively revised to take into account advances in understanding and management that have been achieved over the p…
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Other Authors
Faderl, Stefan H.
Kantarjian, Hagop M.
Estey, Elihu
Responsibility
Stefan H. Faderl, Hagop M. Kantarjian, Elihu Estey, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2021
Physical Description
1 online resource (vi, 289 p.) : 30 illus., 23 illus. in color
Series Title
Hematologic Malignancies
ISBN
9783030536336
9783030536329 (Print ed.)
9783030536343 (Print ed.)
9783030536350 (Print ed.)
ISSN
2197-9766
Subjects (MeSH)
Leukemia, Myeloid, Acute
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Specialty
Hematology
Medical Oncology
Abstract
The new edition of this well-received book provides a timely update of current knowledge on the biology, disease classification, and treatment of the acute leukemias – acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Throughout, the focus is on the provision of state of the art information and guidance that will meet the needs of clinicians. Chapters have been extensively revised to take into account advances in understanding and management that have been achieved over the past few years. In addition, new chapters have been included on selection of AML patients for therapy, a broader discussion of stem cell transplantation in AML, the role of immunotherapy in ALL, the approach to newly diagnosed pediatric ALL, and the diagnosis and management of BCR-ABL-like ALL. New therapies, including investigational ones, are fully covered. As progress continues in the management of acute leukemias this book will be a valuable asset for clinicians at all levels of experience.
Contents
Part I. Acute Myeloid Leukemia -- 1. Acute Myeloid Leukemia: Epidemiology and Etiology -- 2. Clinical Presentation, Diagnosis, and Classification of Acute Myeloid Leukemia -- 3. Insights into the Pathobiology of Secondary AML -- 4. Selection of Patients for Individual Acute Myeloid Leukemia Therapies -- 5. Therapy of Newly Diagnosed Acute Myeloid Leukemia (AML) -- 6. Management of Relapsed/Refractory Acute Myeloid Leukemia -- 7. The Role of Stem Cell Transplant in the Therapy of Acute Myeloid Leukemia (AML) -- 8. Novel and Investigational Therapies in Acute Myeloid Leukemia -- 9. Immune-Based Approaches in AML -- Part II. Acute Lymphoblastic Leukemia -- 10. Acute Lymphoblastic Leukemia: Clinical Presentation, Diagnosis, and Classification -- 11. Frontline Therapy of Newly Diagnosed Acute Lymphoblastic Leukemia -- 12. Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents -- 13. Hematopoietic Cell Transplantation (HCT) for Acute Lymphoblastic Leukemia (ALL) -- 14. Minimal or Measurable Residual Disease in Acute Lymphoblastic Leukemia -- 15. Management of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia -- 16. Ph-Like ALL: Diagnosis and Management -- 17. Adult Burkitt Leukemia/Lymphoma -- 18. Management of Relapsed and Refractory ALL.
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NEW Springer 2021
Format
e-Book
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Acute Myelogenous Leukemia

https://libcat.nshealth.ca/en/permalink/provcat28951
edited by Judith E. Karp. --Totowa, NJ: Humana Press , c2007.
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Online
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Author
Karp, Judith E
Responsibility
edited by Judith E. Karp
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2007
Series Title
Contemporary hematology
ISBN
9781597453226
Subjects (MeSH)
Leukemia, Myeloid, Acute
Subjects (LCSH)
Oncology
Hematology
Format
e-Book
Location
Online
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Acute myelogenous leukemia : genetics, biology and therapy

https://libcat.nshealth.ca/en/permalink/provcat30141
--New York, NY: Springer-Verlag , c2010.
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Online
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Other Authors
Nagarajan, Lalitha
Place of Publication
New York, NY
Publisher
Springer-Verlag
Date of Publication
c2010
Series Vol.
145
Series Title
Cancer treatment and research
ISBN
9780387692593
Subjects (MeSH)
Leukemia, Myeloid, Acute - genetics
Leukemia, Myeloid, Acute - therapy
Subjects (LCSH)
Hematology
Oncology
Format
e-Book
Location
Online
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Acute Myeloid Leukemia

https://libcat.nshealth.ca/en/permalink/provcat46854
Christoph Röllig, Gert J. Ossenkoppele. Springer , 2021.
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Location
Online
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Responsibility
Christoph Röllig, Gert J. Ossenkoppele
Publisher
Springer
Date of Publication
2021
Physical Description
1 online resource (viii, 358 pages) : illustrations
Series Title
Hematologic Malignancies
ISBN
9783030726768
Specialty
Hematology
Medical Oncology
Format
e-Book
Location
Online
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Acute Promyelocytic Leukemia : A Clinical Guide

https://libcat.nshealth.ca/en/permalink/provcat42873
edited by Oussama Abla, Francesco Lo Coco, Miguel A. Sanz. --Cham: Springer , c2018.
Available Online
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Location
Online
This book provides a comprehensive overview on the clinical issues and biology of acute promyelocytic leukemia (APL) and on the molecular mechanisms of targeted therapy with ATRA and ATO. The text covers major topics such as the pathophysiology of APL coagulopathy, biologic and clinical differences between children and adults with APL, and the role of minimal residual disease monitoring. Additionally, the book summarizes historical, current, and future treatment strategies in both adults and ch…
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Other Authors
Abla, Oussama
Lo Coco, Francesco
Sanz, Miguel A.
Responsibility
edited by Oussama Abla, Francesco Lo Coco, Miguel A. Sanz
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xii, 274 p.) : 39 illus., 29 illus. in color
ISBN
9783319642574
9783319642567 (print ed.)
9783319642581 (print ed.)
9783030097134 (print ed.)
Subjects (MeSH)
Leukemia, Promyelocytic, Acute
Specialty
Hematology
Medical Oncology
Abstract
This book provides a comprehensive overview on the clinical issues and biology of acute promyelocytic leukemia (APL) and on the molecular mechanisms of targeted therapy with ATRA and ATO. The text covers major topics such as the pathophysiology of APL coagulopathy, biologic and clinical differences between children and adults with APL, and the role of minimal residual disease monitoring. Additionally, the book summarizes historical, current, and future treatment strategies in both adults and children, while highlighting the most recent therapeutic recommendations for relapsed disease and the evolving indications for autologous and allogeneic stem cell transplant. This volume also features chapters focusing on secondary APL and therapy, late effects, rare presentations such as APL in the elderly and during pregnancy, and rare APL variants that may represent therapeutic challenges. Written by top experts in the field,áAcute Promyelocytic Leukemia: A Clinical Guideáis a valuable resource for clinicians and researchers who treat and investigate this disease in children and adults.
Contents
History of APL -- Molecular Targets of Treatment in APL -- The Leukemic Stem Cell -- The Molecular Genetics of APL -- APL Coagulopathy -- Early Death in APL -- Prognostic Factors in APL -- First-line therapy for APL: Chemotherapy-based approach -- First-line Therapy: ATRA-ATO/Reduced Chemotherapy Approach -- Cure of APL without Chemotherapy -- Minimal Residual Disease in APL -- Treatment of refractory and relapsed APL -- Hematopoietic Stem Cell Transplantation in APL -- APL in Children -- Management of APL in the Elderly -- Special Situations in APL -- APL in Developing Countries: A Chemotherapy-Based Approach -- APL in Developing Countries: ATO based Approach -- Therapy-Related APL -- Rare Acute Leukemia Variants involving Retinoic Acid Receptor Genes -- Management of Treatment-Related Complications in APL.
Format
e-Book
Location
Online
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Adenocarcinoma of the esophagogastric junction

https://libcat.nshealth.ca/en/permalink/provcat28654
--Berlin, Heidelberg: Springer-Verlag , c2010.
Available Online
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Location
Online
Available Online
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Other Authors
Schneider, Paul M
Place of Publication
Berlin, Heidelberg
Publisher
Springer-Verlag
Date of Publication
c2010
Series Vol.
182
Series Title
Recent results in cancer research
ISBN
9783540705796
Subjects (MeSH)
Adenocarcinoma
Esophagogastric Junction
Subjects (LCSH)
Gastroenterology
Oncology
Format
e-Book
Location
Online
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Adipocytic, Vascular and Skeletal Muscle Tumors : A Practical Diagnostic Approach

https://libcat.nshealth.ca/en/permalink/provcat45373
Raf Sciot, Clara Gerosa, Gavino Faa, editors. --Cham: Humana Press , c2020.
Available Online
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Location
Online
This book focuses on the subsets of soft tissue tumors that show adipocytic, vascular or skeletal muscle differentiation. It reviews the surgical pathologists’ approach to diagnosing soft tissue tumors guided by vital morphological and immunohistochemical data in the differential diagnosis of this family of tumors. Written by experts in the field, the text contains a concise yet comprehensive summary of the current status of the field that helps guide diagnosis and patient management, and stimu…
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Other Authors
Sciot, Raf
Gerosa, Clara
Faa, Gavino
Responsibility
Raf Sciot, Clara Gerosa, Gavino Faa, editors
Place of Publication
Cham
Publisher
Humana Press
Date of Publication
c2020
Physical Description
1 online resource (xi, 182 p.)
Series Title
Current clinical pathology
ISBN
9783030374600
9783030374594 (Print ed.)
9783030374617 (Print ed.)
9783030374624 (Print ed.)
ISSN
2197-781X
Subjects (MeSH)
Soft Tissue Neoplasms - diagnosis
Soft Tissue Neoplasms - pathology
Specialty
Diagnosis
Medical Oncology
Pathology
Abstract
This book focuses on the subsets of soft tissue tumors that show adipocytic, vascular or skeletal muscle differentiation. It reviews the surgical pathologists’ approach to diagnosing soft tissue tumors guided by vital morphological and immunohistochemical data in the differential diagnosis of this family of tumors. Written by experts in the field, the text contains a concise yet comprehensive summary of the current status of the field that helps guide diagnosis and patient management, and stimulates investigative efforts. The book is filled with high-quality drawings of the salient histologic features of these various tumors, alongside photomicrographs and tips and tricks that help the relatively untrained or inexperienced eye to recognize the various structures or cell types that comprise each of these lesions. This innovative approach seeks to make recognition of these tumors easier. Adipocytic, Vascular and Skeletal Muscle Tumors serves as a valuable resource for pathologists, oncologists, surgeons, and researchers dealing with and interested in these complex and challenging tumors.
Contents
1. Adipocytic Tumors -- 2. Vascular Tumors -- 3. Skeletal Muscle Tumors.
Format
e-Book
Location
Online
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Adjuvant therapy for breast cancer

https://libcat.nshealth.ca/en/permalink/provcat30193
--Boston, MA: Springer-Verlag US , c2009.
Available Online
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Location
Online
Available Online
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Other Authors
Castiglione, Monica
Piccart, Martine J
Place of Publication
Boston, MA
Publisher
Springer-Verlag US
Date of Publication
c2009
Series Vol.
151
Series Title
Cancer treatment and research
ISBN
9780387751153
Subjects (MeSH)
Adjuvants, Pharmaceutic
Breast Neoplasms - therapy
Chemotherapy, Adjuvant
Radiotherapy, Adjuvant
Subjects (LCSH)
Oncology
Gynecology
Format
e-Book
Location
Online
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Adult acute lymphocytic leukemia : biology and treatment

https://libcat.nshealth.ca/en/permalink/provcat29063
--Totowa, NJ: Springer Science+Business Media , c2011.
Available Online
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Location
Online
Available Online
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Other Authors
Advani, Anjali S
Lazarus, Hillard M
Place of Publication
Totowa, NJ
Publisher
Springer Science+Business Media
Date of Publication
c2011
Series Title
Contemporary hematology
ISBN
9781607617075
Subjects (MeSH)
Precursor Cell Lymphoblastic Leukemia-Lymphoma - Adult
Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy
Subjects (LCSH)
Hematology
Oncology
Format
e-Book
Location
Online
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Adult CNS Radiation Oncology : Principles and Practice

https://libcat.nshealth.ca/en/permalink/provcat42554
Eric L. Chang, Paul D. Brown, Simon S. Lo, Arjun Sahgal, John H. Suh, editors. --Cham: Springer , c2018.
Available Online
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Location
Online
This book elucidates the radiation therapy protocols and procedures for the management of adult patients presenting with primary benign and malignant central nervous system tumors. With the development of new treatment strategies and rapid advancement of radiation technology, it is crucial for radiation oncologists to maintain and refine their knowledge and skills. Dedicated exclusively to adult CNS radiation oncology, this textbook explores CNS tumors ranging from the common to the esoteric as…
Available Online
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Other Authors
Chang, Eric L.
Brown, Paul D.
Lo, Simon S.
Sahgal, Arjun
Suh, John H.
Responsibility
Eric L. Chang, Paul D. Brown, Simon S. Lo, Arjun Sahgal, John H. Suh, editors
Alternate Title
Adult central nervous system radiation oncology
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xxi, 766 p.) : 349 illus., 257 illus. in color
ISBN
9783319428789
9783319428772 (print ed.)
9783319428796 (print ed.)
Subjects (MeSH)
Adult
Central Nervous System Diseases - radiotherapy
Central Nervous System Neoplasms - radiotherapy
Radiation Oncology - methods
Radiotherapy - adverse effects
Specialty
Medical Oncology
Neurology
Radiotherapy
Abstract
This book elucidates the radiation therapy protocols and procedures for the management of adult patients presenting with primary benign and malignant central nervous system tumors. With the development of new treatment strategies and rapid advancement of radiation technology, it is crucial for radiation oncologists to maintain and refine their knowledge and skills. Dedicated exclusively to adult CNS radiation oncology, this textbook explores CNS tumors ranging from the common to the esoteric as well as secondary cancers of metastatic origin. The first half of the book is organized anatomically: tumors of the brain, spinal cord, leptomeninges, optic pathway, ocular choroid, and skull base. The second half covers primary CNS lymphoma, rare CNS tumors, metastatic brain disease, vascular conditions of the CNS, radiation-associated complications, and radiation modalities. Each chapter provides guidance on treatment field design, target delineation, and normal critical structure tolerance constraints in the context of the disease being treated. Learning objectives, case studies, and Maintenance of Certification Self-Assessment Continuing Medical Education-style questions and answers are incorporated throughout the book. This is an ideal guide for radiation oncologists, residents, and fellows, but medical students may also find value in the text.
Contents
Part I. Brain Tumors: Benign -- Meningioma -- Pituitary Adenoma -- Craniopharyngioma -- Vestibular Schwannoma -- Part II. Brain Tumors: Malignant Gliomas -- Low Grade Glioma -- High Grade Gliomas -- Part III. Spine: Benign -- Schwannomas and Neurofibromas -- Spinal Meningioma -- Part IV. Spine: Malignant -- Astrocytic Tumors of Spinal Cord -- Spinal Cord Ependymoma -- Part V. Spine: Metastatic -- Metastatic Epidural Spinal Cord Compression: Conventional Radiotherapy -- Vertebral Body Metastasis -- Part VI. Leptomeningeal Disease -- Evaluation and Workup of Leptomeningeal Disease -- Palliative Radiation Therapy for Leptomeningeal Disease -- Part VII. Optic Pathway Tumors -- Optic Pathway Gliomas -- Optic Nerve Sheath Meningioma -- Part VIII. Ocular Oncology -- Uveal Melanoma -- Part IX. Skull Base Tumor -- Skull Base Tumors -- Part X. Primary Central Nervous System Lymphoma -- Primary Central Nervous System Lymphoma -- Part XI. Rare Tumors -- Choroid Plexus Tumors -- Hemangiopericytoma -- Stereotactic Radiosurgery for Hemangioblastomas -- NF2 Related Tumors and Malignant Peripheral Nerve Sheath Tumors -- Germ Cell Tumors -- Pineal Region Tumors -- Glomus Tumors -- Adult Medulloblastoma -- Intracranial Ependymoma -- Central Neurocytoma -- Part XII. Metastatic Brain Disease -- Prognostic Classification Systems for Brain Metastases -- Neurosurgical Management of Single Brain Metastases -- Multiple Brain Metastases -- Postoperative Treatment for Brain Metastasis -- Part XIII. Vascular Conditions of the CNS -- Vascular Malformation -- Trigeminal Neuralgia -- Part XIV. Radiation Associated Complications -- Brain Radionecrosis -- Spinal Cord Tolerance and Risk of Radiation Myelopathy -- Radiation Optic Neuropathy -- Cerebral Atrophy and Leukoencephalopathy Following Cranial Irradiation -- Hypopituitarism -- Neurocognitive Changes -- Cranial Nerve Palsies, Vascular Damage, and Brainstem Injury -- Part XV. Radiation Modalities Applied to CNS Tumors -- 3-D Conformal Therapy and Intensity Modulated Radiation Therapy/Volumetric Modulated Arc Therapy -- Linac Based Stereotactic Radiosurgery and Hypofractionated Stereotactic Radiotherapy -- Gamma Knife’ Stereotactic Radiosurgery and Hypo-Fractionated Stereototatic Radiotherapy -- Spinal Stereotactic Body Radiotherapy -- Proton Beam Therapy (For CNS Tumors) -- Brachytherapy.
Format
e-Book
Location
Online
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