Atlas of Osteoarthritis
https://libcat.nshealth.ca/en/permalink/provcat39616
Nigel Arden, Francisco Blanco, C. Cooper, Ali Guermazi, Daichi Hayashi, David Hunter, M. Kassim Javaid, Francois Rannou, Frank Roemer, Jean-Yves Reginster.
--Tarporley:
Springer Healthcare
, c2014.
- Available Online
- View e-Book
- Location
- Online
This Atlas provides an up-to-date and comprehensive overview of the historical and current perspectives on osteoarthritis, including the pathophysiology and epidemiology of the disease. Written by leading authors in the field of osteoarthritis, the book discusses classification, etiology and risk factors for osteoarthritis, the disease course and determinants of osteoarthritis progression, clinical features and diagnosis as well as imaging methods to assess joint damage. The Atlas of Osteoarthr…
- Available Online
- View e-Book
- Author
- Arden, N (Nigel)
- Other Authors
- European Society for Clinical and Economic Aspects of Osteoporosis Osteoarthritis and Musculoskeletal Diseases
- Responsibility
- Nigel Arden, Francisco Blanco, C. Cooper, Ali Guermazi, Daichi Hayashi, David Hunter, M. Kassim Javaid, Francois Rannou, Frank Roemer, Jean-Yves Reginster
- Place of Publication
- Tarporley
- Publisher
- Springer Healthcare
- Date of Publication
- c2014
- Physical Description
- 1 online resource (x, 90 p. : 72 illus., 40 illus. in color)
- ISBN
- 9781910315163
- 9781910315156 (print ed.)
- Subjects (MeSH)
- Osteoarthritis
- Notes
- "This book has been published in partnership with the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)."
- Abstract
- This Atlas provides an up-to-date and comprehensive overview of the historical and current perspectives on osteoarthritis, including the pathophysiology and epidemiology of the disease. Written by leading authors in the field of osteoarthritis, the book discusses classification, etiology and risk factors for osteoarthritis, the disease course and determinants of osteoarthritis progression, clinical features and diagnosis as well as imaging methods to assess joint damage. The Atlas of Osteoarthritis concludes with the latest treatment updates including both nonpharmacological and pharmacological treatments, as well as surgical recommendations for patients with the disease. Osteoarthritis is the most common form of joint disease causing joint pain, stiffness, and physical disability among adults. It is an important issue for both the individual and society with its impact on public health continuing to grow as a result of the aging population, the rising prevalence of obesity, and the lack of definitive treatments to prevent or halt the progress of the disease.
- Contents
- Introduction: historical and current perspectives on osteoarthritis -- Epidemiology of osteoarthritis -- Pathophysiology of osteoarthritis -- Clinical features and diagnosis of osteoarthritis -- Assessing joint damage in osteoarthritis -- Treatment of osteoarthritis.
- Format
- e-Book
- Publication Type
- Atlas
- Location
- Online
Bone and Osteoarthritis
https://libcat.nshealth.ca/en/permalink/provcat40586
Felix Bronner and Mary C. Farach-Carson (eds.).
--London:
Springer
, c2007.
- Available Online
- View e-Book
- Location
- Online
Bone and Osteoarthritis places emphasis on the molecular and cellular events that lead to osteoarthritis, stressing the role of subchondral bone, which distinguishes this from other books on the disease. A novel aspect is the attention given to the possible epigenetic basis, together with a discussion of the genetics predisposing to osteoarthritis. Detailed analyses are given of the role of the synovium, of the molecular mechanisms that lead to degradation of the cartilage matrix, of the hypert…
- Available Online
- View e-Book
- Other Authors
- Bronner, Felix
- Farach-Carson, Mary C
- Responsibility
- Felix Bronner and Mary C. Farach-Carson (eds.)
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2007
- Physical Description
- 1 online resource (xiii, 215 p. : 44 illus., 25 illus. in color)
- Series Vol.
- v. 4
- Series Title
- Topics in bone biology
- ISBN
- 9781846287015
- 9781846285134 (print ed.)
- Subjects (MeSH)
- Bone and Bones
- Osteoarthritis
- Abstract
- Bone and Osteoarthritis places emphasis on the molecular and cellular events that lead to osteoarthritis, stressing the role of subchondral bone, which distinguishes this from other books on the disease. A novel aspect is the attention given to the possible epigenetic basis, together with a discussion of the genetics predisposing to osteoarthritis. Detailed analyses are given of the role of the synovium, of the molecular mechanisms that lead to degradation of the cartilage matrix, of the hypertrophy of the cartilage cell, of the anabolic and catabolic roles of cytokines, may lead to novel approaches to clinical treatment, utilizing anabolic mediators or molecules that target steps in the disease process. Also discussed are animal models and how mechano-responsiveness is compromised by mechanical injury. Orthopedics and rheumatology have become close conceptually, as advances in bone and joint biology have enabled bench and translational scientists, as well as practitioners, to approach clinical problems comprehensively. Because bone plays a role in initiating osteoarthritis, therapeutic approaches focusing on bone tissue are included in the discussion of novel treatments. The general topic of osteoarthritis is therefore a timely subject for a series on bone biology. This book, intended for clinicians, researchers and students, provides information that will orient the novice and update the specialist. No other book treats the relationship of bone to osteoarthritis in similar fashion or provides a comparable underpinning of joint pathophysiology.
- Contents
- The Pathogenesis of Osteoarthritis -- The Role of Bone in the Development of Osteoarthritis -- Cytokines, Growth Factors, and Bone-Derived Factors in Cartilage -- The Synovium and Its Role in Osteoarthritis -- Cartilage Matrix Destruction -- Anabolic Mediators of Cartilage Healing -- Chondrocyte Hypertrophy and Apoptosis at the Cartilage-Bone Interface -- Genetic and Epigenetic Aspects of Osteoarthritis -- Animal Models -- Biomechanical Aspects: Joint Injury and Osteoarthritis -- Novel Osteoarthritis Therapeutics.
- Format
- e-Book
- Location
- Online
Clinical Trials in Rheumatoid Arthritis and Osteoarthritis
https://libcat.nshealth.ca/en/permalink/provcat29091
edited by David M. Reid, Colin G. Miller.
--London:
Springer-Verlag
, c2008.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Reid, David M
- Other Authors
- Miller, Colin G
- Responsibility
- edited by David M. Reid, Colin G. Miller
- Place of Publication
- London
- Publisher
- Springer-Verlag
- Date of Publication
- c2008
- Series
- Clinical Trials
- ISBN
- 9781846287428
- Subjects (MeSH)
- Arthritis, Rheumatoid - drug therapy
- Clinical Trials as Topic
- Osteoarthritis - drug therapy
- Subjects (LCSH)
- Orthopedics
- Rheumatology
- Format
- e-Book
- Location
- Online
Comprehensive Treatment of Knee Osteoarthritis : Recent Advances
https://libcat.nshealth.ca/en/permalink/provcat45510
E. Carlos RodrÃguez-Merchán, Primitivo Gómez-Cardero, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book presents the state of the art in and offers up-to-date guidance on the treatment of knee osteoarthritis (KOA), a rapidly evolving and expanding field. Written by experts from leading institutions, it offers a comprehensive overview of this condition, from initial treatment, to surgical approaches and rehabilitation. The book covers a variety of topics, including intra-articular injection options; treatment of uni- and tri-compartmental KOA; infected, unstable and stiff total knee arth…
- Available Online
- View e-Book
- Other Authors
- RodrÃguez-Merchán, E. Carlos
- Gómez-Cardero, Primitivo
- Responsibility
- E. Carlos Rodríguez-Merchán, Primitivo Gómez-Cardero, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (viii, 194 p.) : 51 illus., 33 illus. in color
- ISBN
- 9783030444921
- 9783030444914 (Print ed.)
- 9783030444938 (Print ed.)
- 9783030444945 (Print ed.)
- Subjects (MeSH)
- Osteoarthritis, Knee - therapy
- Specialty
- Orthopedic Procedures
- Rheumatology
- Abstract
- This book presents the state of the art in and offers up-to-date guidance on the treatment of knee osteoarthritis (KOA), a rapidly evolving and expanding field. Written by experts from leading institutions, it offers a comprehensive overview of this condition, from initial treatment, to surgical approaches and rehabilitation. The book covers a variety of topics, including intra-articular injection options; treatment of uni- and tri-compartmental KOA; infected, unstable and stiff total knee arthroplasty; periprosthetic fractures; and prosthetic revision. A wealth of images and cutting edge information make this book an invaluable tool for orthopedic surgeons, rheumatologists, physiatrists, physiotherapists and all healthcare workers involved in the care of these patients.
- Contents
- 1. Initial Treatment of Knee Osteoarthritis: Oral and Topical Drugs -- 2. Physical Medicine and Rehabilitation in Knee Osteoarthritis -- 3. Intra-articular Injections of Corticosteroids and Hyaluronic Acid in Knee Osteoarthritis -- 4. Intra-articular Injections of Platelet-Rich Plasma (PRP) in Knee Osteoarthritis -- 5. Intraarticular Injections of Ozone Gas in Knee Osteoarthritis -- 6. Patellofemoral Osteoarthritis: Conservative and Surgical Treatment -- 7. Knee Joint Distraction (Arthrodiastasis) in Knee Osteoarthritis -- 8. Unicompartmental Knee Osteoarthritis: Alignment Osteotomies -- 9. Unicompartmental Knee Osteoarthritis: Unicompartmental Knee Arthroplasty -- 10. Tricompartmental Knee Osteoarthritis: Total Knee Arthroplasty -- 11. The Infected Total Knee Arthroplasty -- 12. Arterial Injuries in Total Knee Arthroplasty -- 13. Peroneal Nerve Palsy After Total Knee Arthroplasty: Prevalence, Risk Factors, Diagnosis and Management -- 14. Knee Iliotibial Band Friction Syndrome After Total Knee Arthroplasty -- 15. The Stiff Total Knee Arthroplasty -- 16. The Unstable Total Knee Arthroplasty -- 17. Periprosthetic Fractures in Total Knee Arthroplasty -- 18. Revision Total Knee Arthroplasty.
- Format
- e-Book
- Location
- Online
Congenital hip disease in adults
https://libcat.nshealth.ca/en/permalink/provcat33832
George Hartofilakidis, George C. Babis, Kalliopi Lampropoulou-Adamidou.
--Milan:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Hartofilakidis, George
- Other Authors
- Babis, George C
- Lampropoulou-Adamidou, Kalliopi
- Responsibility
- George Hartofilakidis, George C. Babis, Kalliopi Lampropoulou-Adamidou
- Place of Publication
- Milan
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (viii, 170 pages)
- ISBN
- 9788847054929 (electronic bk.)
- 9788847054912
- Subjects (MeSH)
- Arthroplasty, Replacement, Hip
- Hip Dislocation, Congenital
- Osteoarthritis, Hip - surgery
- Subjects (LCSH)
- Hip joint - Dislocation, Congenital
- Hip joint - Abnormalities
- Total hip replacement
- Arthroplasty, Replacement, Hip
- Hip Dislocation, Congenital
- Hip Joint - abnormalities
- Contents
- The Hip: Basic Anatomy -- Osteoarthritis of the Hip -- Congenital Hip Disease: General Aspects, Terminology and Classification -- Epidemiology, Demographics and Natural History -- Treatment Options, Except Total Hip Replacement: Conservative Management and Osteotomies -- Total Hip Replacement: Indications and Preoperative Assessment -- Technical Considerations -- Complications and Results -- Difficult Cases -- Timing for Revision -- Quality of Life After Total Hip Replacement -- Conclusive Messages.
- Format
- e-Book
- Location
- Online
Diagnosis and Management of Hip Disease : Biological Bases of Clinical Care
https://libcat.nshealth.ca/en/permalink/provcat39349
Roy K. Aaron, editor.
(1st ed.)
--Cham:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
Presenting recent advances in clinical diagnosis and treatment derived from an increased understanding of the biology of the hip, this unique text examines hip disease and pathophysiology through the lenses of kinematics, biomechanics, anatomy and metabolism. Opening chapters examine the impact of health care organization on hip care and prevalence and burden of osteoarthritis.Biomechanical considerations of the hip and gait pathomechanics in hip disease are then discussed, followed by chapters…
- Available Online
- View e-Book
- Other Authors
- Aaron, Roy K
- Responsibility
- Roy K. Aaron, editor
- Edition
- 1st ed.
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xv, 299 p. : 9 illus.)
- ISBN
- 9783319199054
- 9783319199047 (print ed.)
- Subjects (MeSH)
- Hip - pathology
- Hip - physiology
- Osteoarthritis - diagnosis
- Osteoarthritis - therapy
- Arthroplasty, Replacement, Hip
- Abstract
- Presenting recent advances in clinical diagnosis and treatment derived from an increased understanding of the biology of the hip, this unique text examines hip disease and pathophysiology through the lenses of kinematics, biomechanics, anatomy and metabolism. Opening chapters examine the impact of health care organization on hip care and prevalence and burden of osteoarthritis.Biomechanical considerations of the hip and gait pathomechanics in hip disease are then discussed, followed by chapters covering femoroacetabular impingement, possible links between OA and metabolic syndrome, osteonecrosis, osteoporosis and Paget's disease. Considerations of risk reduction surrounding hip arthroplasty conclude the text, including device and surgical options for THA, hip sepsis and prevention of perioperative infection, and management of venous thromboembolism. Taken together, this represents a new and important context for the discussions and management of hip disease for orthopedic surgeons and researchers alike.
- Contents
- Health Care Organization and its Impact on Care of Diseases of the Hip -- Prevalence and Societal Burden of Hip Osteoarthritis -- Metabolic Syndrome, Obesity, and Osteoarthritis -- Biomechanical Considerations in Arthritis of the Hip -- Gait Pathomechanics in Hip Disease -- Femoroacetabular Impingement -- Osteonecrosis -- Osteoporosis and Hip Fractures -- Preoperative Management of Paget's Disease -- Metabolic Bone Disease Following Organ Transplantation -- Options for Primary Hip Arthroplasty -- Hip Sepsis and the Prevention of Perioperative Infections -- Venous Thromboembolism in Total Hip Arthroplasty.
- Format
- e-Book
- Location
- Online
Exercise and Physical Functioning in Osteoarthritis : Medical, Neuromuscular and Behavioral Perspectives
https://libcat.nshealth.ca/en/permalink/provcat39585
Joost Dekker, editor.
--New York, NY:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Osteoarthritis (OA) is among the top 10 of most disabling diseases in the Western world. It is the major cause of pain and disability among the elderly. This book provides a contextual review of recent research on neuromuscular factors and behavioral risk factors for functional decline in OA, with a special emphasis on explanatory mechanisms. In addition, the book discusses innovative approaches to exercise and physical activity in OA, derived from research on behavioral and neuromuscular risk …
- Available Online
- View e-Book
- Other Authors
- Dekker, Joost
- Responsibility
- Joost Dekker, editor
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (viii, 132 p. : 25 illus., 19 illus. in color)
- ISBN
- 9781461472155
- 9781461472148 (print ed.)
- Abstract
- Osteoarthritis (OA) is among the top 10 of most disabling diseases in the Western world. It is the major cause of pain and disability among the elderly. This book provides a contextual review of recent research on neuromuscular factors and behavioral risk factors for functional decline in OA, with a special emphasis on explanatory mechanisms. In addition, the book discusses innovative approaches to exercise and physical activity in OA, derived from research on behavioral and neuromuscular risk factors for functional decline in OA. Recent research has shown that neuromuscular factors (such as muscle strength, joint laxity) and behavioral factors (such as avoidance of activity, depressed mood) predict pain and disability in OA. Furthermore, exercise and physical activity are among the dominant interventions aiming at reducing pain and disability, and innovative interventions targeting neuromuscular and behavioral interventions have been recently developed. This research has been published as separate papers, with the result that the field is in need of an integrative contextual review that puts the research into theoretical perspective.
- Contents
- 1. Introduction -- Part I. Osteoarthritis of the knee or hip -- 2. Epidemiology, pathogenesis, and clinical aspects -- 3. Therapeutic options -- Part II. Functional decline -- 4. Risk factors for functional decline -- 5. Neuromuscular mechanisms explaining functional decline -- 6. Behavioral mechanisms explaining functional decline -- Part III. Exercise therapy -- 7. Regular exercise therapy -- 8. Exercise aiming at neuromuscular mechanisms -- 9. Exercise aiming at behavioral mechanisms -- 10. Comorbidity, overweight, and exercise -- 11. Concluding remarks.
- Format
- e-Book
- Location
- Online
Injection Procedures : Osteoarthritis and Related Conditions
https://libcat.nshealth.ca/en/permalink/provcat29616
edited by Todd P. Stitik.
--New York, NY:
Springer Science+Business Media
, c2011.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Stitik, Todd P
- Responsibility
- edited by Todd P. Stitik
- Place of Publication
- New York, NY
- Publisher
- Springer Science+Business Media
- Date of Publication
- c2011
- ISBN
- 9780387765952
- Subjects (MeSH)
- Osteoarthritis - drug therapy
- Injections - methods
- Subjects (LCSH)
- Rheumatology
- Format
- e-Book
- Location
- Online
Management of Knee Osteoarthritis in the Younger, Active Patient : An Evidence-Based Practical Guide for Clinicians
https://libcat.nshealth.ca/en/permalink/provcat40367
David A. Parker, editor.
(1st ed.)
--Berlin, Heidelberg:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book is a rich source of practical guidance on the management of relatively young patients with osteoarthritis of the knee that will assist physicians and allied health professionals in enabling patients to remain active and sustain their quality of life. It provides up-to-date knowledge on the available treatment options, describes the evidence base for each option, and identifies the appropriate timing and indications. The book opens by considering the basic science behind osteoarthritis…
- Available Online
- View e-Book
- Other Authors
- Parker, David A
- Responsibility
- David A. Parker, editor
- Edition
- 1st ed.
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (vii, 165 p. : 58 illus., 19 illus. in color)
- ISBN
- 9783662485309
- 9783662485286 (print ed.)
- Abstract
- This book is a rich source of practical guidance on the management of relatively young patients with osteoarthritis of the knee that will assist physicians and allied health professionals in enabling patients to remain active and sustain their quality of life. It provides up-to-date knowledge on the available treatment options, describes the evidence base for each option, and identifies the appropriate timing and indications. The book opens by considering the basic science behind osteoarthritis, which is critical to management. The many nonsurgical treatment modalities are then discussed, with particular focus on the importance of a multidisciplinary approach. Subsequent chapters address the role of surgical management, covering both techniques that attempt to preserve and possibly restore the native knee joint, such as meniscal and chondral surgery, arthroscopic debridement, and osteotomy for realignment of the joint, and those that involve joint replacement. The arthroplasty component of the text encompasses all areas of prosthetic resurfacing, including localized resurfacing, unicompartmental replacement, and total knee replacement. The book has been produced in cooperation with ISAKOS and the authors constitute an international faculty who provide a truly global perspective on the subject.
- Contents
- Part I. Introduction, and Nonoperative Management -- Osteoarthritis: Definition, Aetiology & Natural History -- Nonoperative Treatment Options for Knee Osteoarthritis -- Part II. Surgical Management -- Meniscus Surgery -- Arthroscopic Debridement in the Presence of Osteoarthritis -- Cartilage Preservation and Restoration Techniques: Evidence-Based Practice -- Unicompartmental Knee Arthroplasty in the Young Patient -- Total Knee Arthroplasty for the Young, Active Patient with Osteoarthritis -- New and Evolving Surgical Techniques -- 10 Conclusions.
- Format
- e-Book
- Location
- Online
Osteoarthritic joint pain
https://libcat.nshealth.ca/en/permalink/provcat22041
Chadwick, Derek J.
Novartis Foundation.
--Chichester, England:
John Wiley and Sons
, 2004.
- Call Number
- WE 348 O85 2004
- Location
- Halifax Infirmary
- Call Number
- WE 348 O85 2004
- Author
- Chadwick, Derek J
- Corporate Author
- Novartis Foundation
- Other Authors
- Goode, Jamie
- Place of Publication
- Chichester, England
- Publisher
- John Wiley and Sons
- Date of Publication
- 2004
- Physical Description
- 292 p.
- Series Vol.
- 260
- Series Title
- Novartis Foundation symposium
- ISBN
- 0470867612
- Subjects (MeSH)
- Osteoarthritis - Congresses
- Pain - Congresses
- Format
- Book
- Location
- Halifax Infirmary
- Loan Period
- 3 weeks
Osteoarthritis of the Knee
https://libcat.nshealth.ca/en/permalink/provcat28864
by Michel Bonnin, Pierre Chambat.
--Paris:
Springer-Verlag France
, c2008.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Bonnin, Michel
- Other Authors
- Chambat, Pierre
- Responsibility
- by Michel Bonnin, Pierre Chambat
- Place of Publication
- Paris
- Publisher
- Springer-Verlag France
- Date of Publication
- c2008
- ISBN
- 9782287741753
- Subjects (MeSH)
- Arthroplasty, Replacement, Knee
- Knee Joint - pathology
- Knee Prosthesis
- Osteoarthritis, Knee - surgery
- Osteotomy
- Subjects (LCSH)
- Orthopedic surgery
- Format
- e-Book
- Location
- Online
Osteoarthritis : Pathogenesis, Diagnosis, Available Treatments, Drug Safety, Regenerative and Precision Medicine
https://libcat.nshealth.ca/en/permalink/provcat39341
Mohit Kapoor, Nizar N. Mahomed, editors.
--Cham:
Springer International Publishing : Imprint: Adis
, c2015.
- Available Online
- View e-Book
- Location
- Online
This comprehensive book grants readers exclusive insight into current advancements in the field of osteoarthritis (OA). Contributions from leading scientists and clinicians provide a detailed introduction into current understanding of the pathogenesis of OA, different joint structures affected by this debilitating disease (hip, knee, elbow, shoulder, foot, ankle, hand, wrist, and spine), current knowledge and practice in imaging, joint conservative strategies, OA biomarkers as well as currently…
- Available Online
- View e-Book
- Other Authors
- Kapoor, Mohit
- Mahomed, Nizar N
- Responsibility
- Mohit Kapoor, Nizar N. Mahomed, editors
- Place of Publication
- Cham
- Publisher
- Springer International Publishing : Imprint: Adis
- Date of Publication
- c2015
- Physical Description
- 1 online resource (x, 278 p. : 30 illus., 10 illus. in color)
- ISBN
- 9783319195605
- 9783319195599 (print ed.)
- Subjects (MeSH)
- Osteoarthritis
- Abstract
- This comprehensive book grants readers exclusive insight into current advancements in the field of osteoarthritis (OA). Contributions from leading scientists and clinicians provide a detailed introduction into current understanding of the pathogenesis of OA, different joint structures affected by this debilitating disease (hip, knee, elbow, shoulder, foot, ankle, hand, wrist, and spine), current knowledge and practice in imaging, joint conservative strategies, OA biomarkers as well as currently available treatments, their safety profile and future therapeutic targets. This book further discusses the potential of regenerative therapies and recent advances in OA Personalized Medicine, and how collection of OA patients' phenotypic, genetic and proteomic data is able to direct treatment strategies through Bio-Informatics. Dr. Mohit Kapoor is an Associate Professor in the Department of Surgery and the Department of Laboratory Medicine and Pathobiology at the University of Toronto, Canada. He heads the cartilage biology research group within the Arthritis Program at the Toronto Western Research Institute, University Health Network, Toronto. His research program is directed towards understanding the complex pathophysiology of OA and identifying new therapeutic strategies to identify and counteract the destruction of the articular cartilage during OA. Specifically, his research is focused towards (a) understanding the mechanisms that are essential for maintaining articular cartilage homeostasis and mechanisms that trigger cell death and articular cartilage damage, and (b) identifying new OA biomarkers. Dr. Kapoor has published over 50 research articles, reviews and book chapters and is a recipient of several prestigious research awards. Dr. Nizar Mahomed is head of the Division of Orthopaedic Surgery at the University Health Network and Professor in the Department of Surgery at the University of Toronto, Canada. He is Nicki and Bryce Douglas Chair and Smith & Nephew Chair in Orthopaedic Surgery. Clinically he focuses on complex primary and revision hip and knee replacement surgery. He has over 100 publications and book chapters. His research interests are in the areas of health systems research focusing on models of care for orthopaedic conditions and translational research looking at regenerative options for OA. Dr. Mahomed has received several awards for his research and is the recipient of the first CIHR-CMAJ Top Canadian Achievements in Health Research Award. As Medical Director of the Arthritis Program at University Health Network, he leads the largest integrated Arthritis Program in Canada.
- Contents
- 1. Pathogenesis of Osteoarthritis -- 2. Hip and Knee Osteoarthritis -- 3. Shoulder and Elbow Osteoarthritis -- 4. Lumbar Spine Osteoarthritis -- 5. Ankle Arthritis -- 6. Hand and Wrist Osteoarthritis -- 7. Imaging in Osteoarthritis -- 8. Osteoarthritis: Joint Conservation Strategies -- 9. Osteoarthritis Biomarkers -- 10. Drug/Agent Treatments for Osteoarthritis: Present and Future -- 11. Safety Profile of Current OA Therapies: Evidence from Clinical Trials -- 12. Regenerative Medicine Approaches for Treatment of Osteoarthritis -- 13. Precision Medicine for Osteoarthritis.
- Format
- e-Book
- Location
- Online
Post-Traumatic Arthritis : Pathogenesis, Diagnosis and Management
https://libcat.nshealth.ca/en/permalink/provcat38931
Steven A. Olson, MD, Farshid Guilak, PhD, editors.
--Boston, MA:
Springer US
, c2015.
- Available Online
- View e-Book
- Location
- Online
Bringing together the most up-to-date research on post-traumatic arthritis (PTA) and its management, this book is a comprehensive presentation of the current thinking on all aspects of the mechanisms of joint injury and subsequent development of PTA. Divided into thematic sections, it includes discussions of the incidence and burden of PTA, both in society at large and in the military population specifically; the relevant experimental work on PTA, from basic science to animal models; peri-artic…
- Available Online
- View e-Book
- Other Authors
- Olson, MD, Steven A
- Guilak, PhD, Farshid
- Responsibility
- Steven A. Olson, MD, Farshid Guilak, PhD, editors
- Place of Publication
- Boston, MA
- Publisher
- Springer US
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xx, 360 p. : 98 illus., 65 illus. in color)
- ISBN
- 9781489976062
- 9781489976055 (print ed.)
- Subjects (MeSH)
- Biomarkers
- Cartilage, Articular - pathology
- Joint Deformities, Acquired - therapy
- Osteoarthritis - diagnosis
- Osteoarthritis - etiology
- Osteoarthritis - therapy
- Abstract
- Bringing together the most up-to-date research on post-traumatic arthritis (PTA) and its management, this book is a comprehensive presentation of the current thinking on all aspects of the mechanisms of joint injury and subsequent development of PTA. Divided into thematic sections, it includes discussions of the incidence and burden of PTA, both in society at large and in the military population specifically; the relevant experimental work on PTA, from basic science to animal models; peri-articular tissue responses to joint injury and potential mechanisms of PTA; the current clinical assessment and treatment of common joint injuries leading to PTA; and emerging technologies and treatments for PTA, including biomarkers and stem cell therapies. Taken together, it will be an invaluable resource for orthopedic surgeons, rheumatologists and other joint injury researchers and clinicians.
- Contents
- Section I: The Problem of Post-Traumatic Arthritis -- Arthritis that Develops after Joint Injury: Is it Post-Traumatic Arthritis or Post-Traumatic OsteoArthritis? -- Post-Traumatic Arthritis: Definitions and Burden of Disease -- Arthritis after Joint Injury: The Military Experience -- Section II: Experimental Models of Joint Injury -- In Vitro Cartilage Explant Injury Models -- Animal Models of Meniscal Injury in Post-Traumatic Arthritis -- Anterior Cruciate Transection/Disruption Models of Posttraumatic Arthritis -- Closed Joint ACL Disruption Murine Model of PTA -- Whole Joint Models of Articular Injury and Articular Fracture -- Instability: Dynamic Loading Models -- Survey of Animal Models in Post-Traumatic Arthritis: Choosing the Right Model to Answer the Right Question -- Section III: Peri-articular Tissue Response to Joint Injury -- The Response of Cartilage to Injury -- The Response of the Subchondral Bone to Injury -- Genetic Variability in the Response to Injury -- Aging and Post-Traumatic Arthritis -- Potential Mechanisms of PTA: Cell Death -- Potential Mechanisms of PTOA: Inflammation -- Potential Mechanisms of PTA: Oxidative Stress -- Potential Mechanisms of PTA: Alterations in Joint Loading -- Section IV: Clinical Assessment and Treatment of Patients with Joint Injury -- Imaging Specific to Cartilage Injury -- Outcomes of ACL Injury: The MOON Consortium -- Current Treatment and Outcomes of Intra-articular Fractures -- Non-arthroplasty Treatments for PTA in the Lower Extremity -- Results of Arthroplasty in Post-Traumatic Arthritis -- Section V: Developing and Future Assessment and Therapies -- Measurement of Severity of Injury after Articular Fracture and Correlation with Post-Traumatic Arthritis Development -- Biomarkers of PTA -- Potential Targets for Pharmacologic Therapies for Prevention of PTA -- Stem Cell Therapies for Post-Traumatic Arthritis -- Unanswered Questions and Future Directions in Post-Traumatic Arthritis.
- Format
- e-Book
- Location
- Online
Trapeziometacarpal Joint Osteoarthritis : Diagnosis and Treatment
https://libcat.nshealth.ca/en/permalink/provcat42538
Simona Odella.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book describes the anatomy and biomechanics of the trapeziometacarpal joint and explains the pathogenesis and treatment of trapeziometacarpal joint osteoarthritis, also known as rhizarthrosis. The discussion of treatment sets out both conservative and surgical approaches, clearly explaining the indications for the various options, as well as their advantages and disadvantages. The trapeziometacarpal joint is a phylogenetically recent articulation that permits the pinching movements of the …
- Available Online
- View e-Book
- Author
- Odella, Simona
- Responsibility
- Simona Odella
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (viii, 104 p.) : 64 illus., 52 illus. in color
- ISBN
- 9783319443362
- 9783319443348 (print ed.)
- 9783319443355 (print ed.)
- Subjects (MeSH)
- Carpometacarpal Joints - pathology
- Osteoarthritis - diagnosis
- Osteoarthritis - therapy
- Specialty
- Rheumatology
- Abstract
- This book describes the anatomy and biomechanics of the trapeziometacarpal joint and explains the pathogenesis and treatment of trapeziometacarpal joint osteoarthritis, also known as rhizarthrosis. The discussion of treatment sets out both conservative and surgical approaches, clearly explaining the indications for the various options, as well as their advantages and disadvantages. The trapeziometacarpal joint is a phylogenetically recent articulation that permits the pinching movements of the index finger and thumb so important in daily activities. Degenerative disease involving the trapeziometacarpal joint is an important disabling condition that affects predominantly females over 50 years old. Although a number of treatments are now available, there is no single gold standard. Conservative treatments can control pain yet are unable to halt progression of the articular aging, while none of the surgical solutions employed when conservative treatments prove insufficient can be considered perfect. For example, use of a spacer can restore strength but does not always completely alleviate pain while arthroplasty eradicates pain within a few weeks but cannot restore strength. In thoroughly reviewing the available treatments, this book will enable the practitioner to select the best option for the individual patient.
- Contents
- 1. Anatomy of the Trapeziometacarpal Joint -- 2. Physical and Radiological Evaluation -- 3. Etiopathology -- 4. Non-surgical Treatment -- 5. Portals in the Arthroscopy of the Wrist and of the Small Joints -- 6. Trapeziometacarpal Joint Arthrosis: Arthroscopic Treatment -- 7. Surgical Approaches and Techniques.
- Format
- e-Book
- Location
- Online
Treatment of Osteoarthritic Change in the Hip : Joint Preservation or Joint Replacement?
https://libcat.nshealth.ca/en/permalink/provcat28668
edited by Muroto Sofue, Naoto Endo.
--Tokyo:
Springer
, c2007.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Sofue, Muroto
- Other Authors
- Endo, Naoto
- Responsibility
- edited by Muroto Sofue, Naoto Endo
- Place of Publication
- Tokyo
- Publisher
- Springer
- Date of Publication
- c2007
- ISBN
- 9784431382003
- Subjects (LCSH)
- Orthopedic surgery
- Format
- e-Book
- Location
- Online
