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ABC of sleep medicine

https://libcat.nshealth.ca/en/permalink/provcat31315
Paul Reading. --Chichester, West Sussex, UK: Wiley-Blackwell , 2013.
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Location
Online
Available Online
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Author
Reading, Paul
Responsibility
Paul Reading
Place of Publication
Chichester, West Sussex, UK
Publisher
Wiley-Blackwell
Date of Publication
2013
Physical Description
1 online resource (vii, 58 p.)
Series Title
ABC series
ISBN
9781118523322
Subjects (MeSH)
Sleep disorders - pathology
Sleep - physiology
Contents
Normal versus abnormal sleep -- Diagnosing sleep disorders -- Excessive daytime sleepiness -- Sleep apnoea syndrome -- Insomnia -- Secondary (co-morbid) insomnia -- The parasomnias -- Sleep disorders in children -- Sleep in neurodegenerative disease -- Sleep in psychiatric disease -- Drugs used in sleep medicine.
Format
e-Book
Location
Online
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Abdominal obesity and the endocannabinoid system : from basic aspects to clinical management of related cardiometabolic risk

https://libcat.nshealth.ca/en/permalink/provcat24568
Despres, Jean-Pierre. --New York, NY: Informa Healthcare , 2009.
Call Number
WD 210 A135 2009
Location
Dickson Building
Call Number
WD 210 A135 2009
Author
Despres, Jean-Pierre
Other Authors
Di Marzo, Vincenzo
Place of Publication
New York, NY
Publisher
Informa Healthcare
Date of Publication
2009
Physical Description
265 p.
ISBN
9781420060843
Subjects (MeSH)
Obesity, Abdominal - physiopathology
Obesity - complications
Endocannabinoids - physiology
Abdominal Fat
Metabolic Syndrome X
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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Acid-Base Disorders : Clinical Evaluation and Management

https://libcat.nshealth.ca/en/permalink/provcat44942
Alluru S. Reddi. --Cham: Springer , c2020.
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Location
Online
This book provides a concise yet comprehensive overview of acid-base disorders. Each chapter reviews an acid-base disorder, covering pathophysiology, evaluation, and management of the disorder. The chapters include clinical cases and a Q&A section, based on scenarios and questions that clinicians regularly encounter when treating patients with these disorders. The book concludes with two chapters on acid-based disorders in special patient populations, including critically ill patients, pregnant…
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Author
Reddi, Alluru S.
Responsibility
Alluru S. Reddi
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (vii, 317 p.) : 32 illus., 3 illus. in color
ISBN
9783030288952
9783030288945 (Print ed.)
9783030288969 (Print ed.)
Subjects (MeSH)
Acid-Base Imbalance - diagnosis
Acid-Base Imbalance - therapy
Specialty
Physiology
Abstract
This book provides a concise yet comprehensive overview of acid-base disorders. Each chapter reviews an acid-base disorder, covering pathophysiology, evaluation, and management of the disorder. The chapters include clinical cases and a Q&A section, based on scenarios and questions that clinicians regularly encounter when treating patients with these disorders. The book concludes with two chapters on acid-based disorders in special patient populations, including critically ill patients, pregnant patients, and surgical patients. Written by an expert in the field, Acid-Base Disorders: Clinical Evaluation and Management is a state-of-the-art resource that should assist clinicians and practitioners in managing patients with acid-base disorders.
Contents
Introduction to Acid-Base -- Basic Acid-Base Chemistry and Physiology -- Methods to Assess Acid-Base Disorders -- Acid-Base Disorders: General Considerations and Evaluation -- Lactic Acidosis -- Ketoacidosis -- Toxin-Induced Acid-Base Disorders -- Renal Tubular Acidosis -- Acid-Base Disorders in Gastrointestinal Diseases -- Acid-Base Disorders in Kidney Disease -- Metabolic Alkalosis -- Respiratory Acidosis -- Respiratory Alkalosis -- Mixed Acid-Base Disorders -- Drug-Induced Acid-Base Disorders -- Acid-Base Disorders in Critically Ill Patients -- Acid-Base Disorders in Liver Disease -- Acid-Base Disorders in Total Parenteral Nutrition -- Acid-Base Disorders in Pregnancy -- Acid-Base Disorders in Surgical Patients.
Format
e-Book
Location
Online
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The ACL Handbook : Knee Biology, Mechanics, and Treatment

https://libcat.nshealth.ca/en/permalink/provcat40712
Martha M. Murray, Patrick Vavken, Braden C. Fleming, editors. --New York, NY: Springer , c2013.
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ACL injuries affect the lives of hundreds of thousands of people each year. Treatment is far from perfect, and physicians and patients face challenges such as high failure rates in adolescent athletes and the inability to slow the accelerated progression of arthritis after an ACL rupture, for example. The ACL Handbook takes a complete view of ACL injuries and treatments, discussing: Normal ACL and knee mechanics; The body's response to ACL injury; Development of new treatment methods. Ideal for…
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Other Authors
Murray, Martha M
Vavken, Patrick
Fleming, Braden C
Responsibility
Martha M. Murray, Patrick Vavken, Braden C. Fleming, editors
Alternate Title
Anterior cruciate ligament handbook
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xi, 317 p. : ill.)
ISBN
9781461407607
9781461407591 (print ed.)
Subjects (MeSH)
Anterior Cruciate Ligament - injuries
Anterior Cruciate Ligament Reconstruction - methods
Models, Biological
Tissue Engineering
Wound Healing - physiology
Abstract
ACL injuries affect the lives of hundreds of thousands of people each year. Treatment is far from perfect, and physicians and patients face challenges such as high failure rates in adolescent athletes and the inability to slow the accelerated progression of arthritis after an ACL rupture, for example. The ACL Handbook takes a complete view of ACL injuries and treatments, discussing: Normal ACL and knee mechanics; The body's response to ACL injury; Development of new treatment methods. Ideal for orthopedists, sports medicine physicians, and physical therapists, The ACL Handbook is a unique resource for information on the basic and applied science of ACL injury, repair, and the future of treatment.
Contents
Part I. ACL Injury: The Clinical Problem -- ACL Injury Epidemiology -- History of ACL Treatment and Current Gold Standard of Care -- ACL Clinical Outcomes -- ACL Treatment in the Skeletally Immature Patient -- Part II. ACL Injury: The Biologic Problem -- The Biology of the Normal ACL -- The Role of Inflammation and Blood Cells in Wound Healing -- The ACL Response to Injury -- The Biology of Impaired Healing of Joint Issues -- Part III. Translational Medicine: In Vitro and In Vivo Models -- Translational Medicine -- In Vitro Models of ACL Injury -- In Vivo Models of ACL Injury (Central Defect, Porcine, Ovine, Canine) -- Tissue Engineering of Ligaments and Tendons -- Outcome Assessment for ACL Tissue Engineering -- Part IV. Stimulating Healing of the ACL Using Tissue Engineering -- Scaffolds and Biologic Additives for ACL Surgery -- Use of Biologics to Treat Partial ACL Tears -- Can We Get a Complete ACL Tear to Heal? -- The Effects of Platelets and Their Concentration on ACL Healing -- The Effects of WBCs and RBCs on Ligament Healing -- Safety of the Bioenhanced Repair -- Re-Innervation and Revascularization in Engineered ACL Healing -- Bio-enhancement of ACL Graft Healing -- The Effects of Age and Skeletal Maturity on Healing of the Anterior Cruciate Ligament.
Format
e-Book
Location
Online
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Active living, cognitive functioning, and aging

https://libcat.nshealth.ca/en/permalink/provcat22851
Poon, Leonard W. --Champaign, IL: Human Kinetics , 2006.
Call Number
WT 104 A267 2006
Location
Halifax Infirmary
Call Number
WT 104 A267 2006
Author
Poon, Leonard W
Other Authors
Chodzko-Zajko, Wojtek
Tomporowski, Phillip D
Place of Publication
Champaign, IL
Publisher
Human Kinetics
Date of Publication
2006
Physical Description
250 p.
Series Vol.
v. 1
Series Title
Aging, exercise, and cognition series
ISBN
0736057854
9780736057851
Subjects (MeSH)
Aging - physiology
Cognition - physiology - aged
Exercise - physiology - Aged
Health Behavior - Aged
Physical Fitness - Aged
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Acute & chronic wounds : current management concepts

https://libcat.nshealth.ca/en/permalink/provcat41081
Ruth A. Bryant, Denise P. Nix [editors]. (Fifth edition) --St. Louis, MO: Elsevier , c2016.
Call Number
WO 185 A189 2016 REF
Location
Dickson Building
Sub-Location
REFERENCE
Call Number
WO 185 A189 2016 REF
Other Authors
Bryant, Ruth A.
Nix, Denise P.
Responsibility
Ruth A. Bryant, Denise P. Nix [editors]
Edition
Fifth edition
Place of Publication
St. Louis, MO
Publisher
Elsevier
Date of Publication
c2016
Physical Description
xii, 632 pages
ISBN
9780323316217
Subjects (MeSH)
Wounds and injuries - nursing
Wounds and Injuries - therapy
Patient Care Planning
Skin Ulcer - complications
Wound healing - physiology
Contents
Section I. Foundations -- Section II. Pressure ulcers -- Section III. Lower extremity wounds -- Section IV. Wound bed preparation -- Section V. Biophysical and biologic agents -- Section VI. Critical cofactors -- Section VII. Acute and traumatic wounds -- Section VIII. Special patient populations -- Appendix A. Examples of tools used to support skin and wound care -- Appendix B. Self-assessment exercices.
Format
Book
Location
Dickson Building
Sub-Location
REFERENCE
Loan Period
In library use
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Adipocytokines, Energy Balance, and Cancer

https://libcat.nshealth.ca/en/permalink/provcat41392
Ofer Reizes, Nathan A. Berger, editors. --Cham: Springer , 2017.
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Adipocytokines provide the circuitry by which adipose tissue communicates among its component cells which include adipocytes, stromal cells, immune cells and vascular elements, with adipose tissue depots in other locations throughout the body and with other tissues in order to regulate physiologic processes of energy intake, utilization, and distribution. Since disturbances, both qualitative and quantitative, in adipocytokine function contribute significantly to many of the comorbidities associ…
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Other Authors
Reizes, Ofer
Berger, Nathan A
Responsibility
Ofer Reizes, Nathan A. Berger, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xii, 302 pages) : 19 illus., 16 illus. in color
Series Vol.
12
Series Title
Energy balance and cancer
ISBN
9783319416779
9783319416755 (print ed.)
ISSN
2199-2622
Subjects (MeSH)
Adipokines
Energy metabolism - physiology
Neoplasms - etiology
Neoplasms - metabolism
Obesity - complications
Abstract
Adipocytokines provide the circuitry by which adipose tissue communicates among its component cells which include adipocytes, stromal cells, immune cells and vascular elements, with adipose tissue depots in other locations throughout the body and with other tissues in order to regulate physiologic processes of energy intake, utilization, and distribution. Since disturbances, both qualitative and quantitative, in adipocytokine function contribute significantly to many of the comorbidities associated with obesity, including diabetes, cardiovascular disease and cancer, this volume, which discusses most of the major adipocytokines independently and collectively and their roles in normal and pathologic processes, should be useful to all individuals seeking a deeper understanding of these processes. Moreover, it provides a valuable complement to the series on Energy Balance and Cancer, in which each volume is focused on a specific aspect of this process, which now constitutes an expanding problem as the obesity pandemic continues and more of the population reaches the age where cancer is most prevalent. This volume should provide a valuable resource to all clinicians and scientists engaged in caring for susceptible patients and in exploring the relation between energy balance and cancer as well as an important platform to providing the background for research development.
Contents
Preface -- 1. Adipocytes, Adipocytokines, and Cancer -- 2. Adiponectin, Obesity, and Cancer -- 3. Leptin in Cancer; Epidemiology and Mechanisms -- 4. Leptin Signaling Pathways as Therapeutic Targets in Cancer -- 5. Retinol Binding Protein 4: Role in Diabetes and Cancer -- 6. Visfatin, Obesity, and Cancer -- 7. Apelin and Cancer -- 8. Novel Adipocytokines: Monocyte Chemotactic Protein-1, Plasminogen Activator Inhibitor-1, Chemerin -- 9. Resistin, Obesity, and Cancer -- 10. CRP Role in Cancer -- 11. GI Peptides, Energy Balance and Cancer -- Index.
Format
e-Book
Location
Online
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Adipose tissue and adipokines in health and disease

https://libcat.nshealth.ca/en/permalink/provcat33256
Giamila Fantuzzi, Theodore Mazzone, editors. (Second edition) --New York: Humana Press , c2014.
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Location
Online
The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous…
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Other Authors
Fantuzzi, Giamila
Mazzone, Theodore
Responsibility
Giamila Fantuzzi, Theodore Mazzone, editors
Edition
Second edition
Place of Publication
New York
Publisher
Humana Press
Date of Publication
c2014
Physical Description
1 online resource (xxvi, 372 pages)
Series
Nutrition and Health
Series Title
Nutrition and health (Totowa, N.J.)
ISBN
9781627037709 (electronic bk.)
9781627037693
Subjects (MeSH)
Adipocytes - physiology
Adipose Tissue - physiology
Obesity - complications
Obesity - etiology
Subjects (LCSH)
Adipose tissues
Fat cells
Adipocytes
Abstract
The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous volume but as the field has evolved, some areas covered in the first edition have been refocused to address the new knowledge. The volume is divided in four sections: the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint. The chapters are written by experts in their fields and include the most up to date scientific information. Adipose Tissue and Adipokines in Health and Disease, Second Edition is a useful resource for physicians interested in adipose tissue biology and basic scientists who want to know more about applied aspects of the field. The book targets endocrinologists, residents and fellows, internists, nutritionists and general practitioners who are exposed to an ever-expanding obese population.
Contents
Adipose Tissue: Structure and Function -- Adipose Tissue in Evolution -- Adipose Stem Cells and Adipogenesis -- Adipose Stem Cells and Adipogenesis -- Metabolism of White Adipose Tissue -- Bad Fat or Just More Fat? Murine Models of Metabolically Healthy Obesity -- The Aging Adipose Organ: Lipid Redistribution, Inflammation, and Cellular Senescence -- Adipokines: Leptin and Adiponectin in the Regulation of Inflammatory and Immune Responses -- Adipose Tissue Inflammation and Adipocyte Dysfunction in Obesity -- Adipose Tissue Inflammation -- Endoplasmic Reticulum Stress and Adipose Tissue Function -- Autophagy in White Adipose Tissue -- Obesity and Micronutrient Deficiencies -- Obesity -- Epidemiology of Obesity in Children -- Genetics of Obesity -- Epigenetics of Obesity -- Consequences of Rapid Weight Loss -- Adipose Tissue and Disease -- Human Lipodystrophy: An Update in Molecular Genetics and Possible Mechanisms of Fat Loss -- Adipose Tissue and Type 2 Diabetes Mellitus -- Adipokines in Nonalcoholic Fatty Liver Disease -- Obesity and Cardiovascular Disease -- Respiratory Diseases in Obesity -- Adiposity and Kidney Disease -- Obesity and Joint Disease -- Obesity and Colon and Postmenopausal Breast Cancer.
Format
e-Book
Location
Online
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Adler's physiology of the eye

https://libcat.nshealth.ca/en/permalink/provcat31646
Leonard A. Levin, Siv F.E. Nilsson, James Ver Hoeve ... [et al.]. (11th ed.) --Edingburg: Saunders Elsevier , c2011.
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Location
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Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv F.E. Nilsson, James Ver Hoeve, and Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye, updated to enhance your understanding of ocular function. This full-color, user-friendly edition captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. A new organization by function, rather than anatomy, help…
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Other Authors
Levin, Leonard A
Responsibility
Leonard A. Levin, Siv F.E. Nilsson, James Ver Hoeve ... [et al.]
Edition
11th ed.
Alternate Title
Physiology of the eye
Place of Publication
Edingburg
Publisher
Saunders Elsevier
Date of Publication
c2011
Physical Description
1 online resource (xii, 795 p.)
ISBN
9780323081160
Subjects (MeSH)
Ocular Physiological Phenomena
Subjects (LCSH)
Eye--Physiology
Abstract
Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv F.E. Nilsson, James Ver Hoeve, and Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye, updated to enhance your understanding of ocular function. This full-color, user-friendly edition captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. A new organization by function, rather than anatomy, helps you make a stronger connection between physiological principles and clinical practice; and more than 1,000 great new full-color illustrations help clarify complex concepts.
Contents
Focusing of an image on the retina -- Physiology of optical media -- Direction of gaze -- Nutrition of the eye -- Protection of the eye -- Photoreception -- Visual processing in the retina -- Non-perceptive vision -- Visual processing in the brain -- Visual perception -- Development and deprivation of vision.
Access
Registration required for PDF access.
Format
e-Book
Location
Online
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Adler's physiology of the eye : clinical applications

https://libcat.nshealth.ca/en/permalink/provcat52772
[edited by] Robert A. Moses [and] William M. Hart. (8th ed.) --St. Louis, MO: C.V. Mosby , 1987.
Call Number
WW 103 M60 1987
Location
IWK Health Sciences Library
Call Number
WW 103 M60 1987
Author
Moses, Robert A.
Other Authors
Hart, William M.
Adler, Francis Heed
Responsibility
[edited by] Robert A. Moses [and] William M. Hart
Edition
8th ed.
Alternate Title
Physiology of the eye
Place of Publication
St. Louis, MO
Publisher
C.V. Mosby
Date of Publication
1987
Physical Description
709 p.
ISBN
801635640
Subjects (MeSH)
Eye - physiology
Notes
Missing pages 1-8.
The most recent edition of this book is available online at: https://www.clinicalkey.com/#!/browse/book/3-s2.0-C20090457647 .
Format
Book
Location
IWK Health Sciences Library
Copies
1
Loan Period
2 weeks
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Adler's physiology of the eye : clinical applications

https://libcat.nshealth.ca/en/permalink/provcat52773
Moses, Robert A. (7th ed.) --St. Louis, MO: Mosby , 1981.
Call Number
WW 103 A56 1981
Location
IWK Health Sciences Library
Call Number
WW 103 A56 1981
Author
Moses, Robert A.
Edition
7th ed.
Place of Publication
St. Louis, MO
Publisher
Mosby
Date of Publication
1981
Physical Description
747 p. ; ill.
ISBN
801635411
Subjects (MeSH)
Eye - physiology
Notes
The most recent edition of this book is available online at: https://www.clinicalkey.com/#!/browse/book/3-s2.0-C20090457647 .
Format
Book
Location
IWK Health Sciences Library
Copies
1
Loan Period
2 weeks
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Adrenomedullin in cardiovascular disease

https://libcat.nshealth.ca/en/permalink/provcat28313
--Boston, MA: Springer Science+Business Media , c2005.
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Location
Online
Available Online
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Other Authors
Nishikimi, Toshio
Place of Publication
Boston, MA
Publisher
Springer Science+Business Media
Date of Publication
c2005
Series Vol.
19
Series Title
Basic science for the cardiologist
ISBN
9780387254050
Subjects (MeSH)
Cardiovascular Diseases - drug therapy
Natriuretic Agents - therapeutic use
Adrenomedullin - physiology
Adrenomedullin - therapeutic use
Subjects (LCSH)
Cardiology
Biochemistry
Format
e-Book
Location
Online
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Advanced Surgical Facial Rejuvenation : Art and Clinical Practice

https://libcat.nshealth.ca/en/permalink/provcat31106
Anthony Erian, Melvin A. Shiffman (editors). --Berlin, Heidelberg: Springer , c2012.
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Location
Online
This richly illustrated book covers all aspects of aesthetic facial surgery, from anatomy to the variety of procedures employed in facial surgery, including ancillary techniques such as chemical peel, laser, and facial fillers. Both newer techniques and variations on older approaches are carefully presented and discussed. In addition, preoperative care is analyzed, and detailed attention is devoted to problems related to HIV infection, anesthesia, complications, and psychological aspects. The c…
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Other Authors
Erian, Anthony
Shiffman, Melvin A
Responsibility
Anthony Erian, Melvin A. Shiffman (editors)
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xiv, 740 p. : 653 ill., 620 ill. in color)
ISBN
9783642178382
Subjects (MeSH)
Face - surgery
Cosmetic Techniques
Rejuvenation - physiology
Subjects (LCSH)
Dermatology
Otorhinolaryngology
Surgery
Abstract
This richly illustrated book covers all aspects of aesthetic facial surgery, from anatomy to the variety of procedures employed in facial surgery, including ancillary techniques such as chemical peel, laser, and facial fillers. Both newer techniques and variations on older approaches are carefully presented and discussed. In addition, preoperative care is analyzed, and detailed attention is devoted to problems related to HIV infection, anesthesia, complications, and psychological aspects. The contributors are all internationally acclaimed experts in the field. The book will be an invaluable source of information for residents and fellows, practicing aesthetic surgeons, and surgeons in a variety of related fields.
Contents
Part I: Anatomy -- Part II: Anesthesia -- Part III: Preoperative and postoperative -- Part IV: Psychological aspects -- Part V: Techniques -- Hair transplantation -- Ablative laser facial resurfacing -- Photorejuvenation -- Superficial and medium peel -- Deep phenol peel -- Facial Implants -- Injectable Facial Fillers -- Submentoplasty And Facial Liposuction -- Bio-Lifting And Bio-Resurfacing -- Personal Technique Of Doing Office Facial Surgery -- Design And Management Of The Anterior Hairline -- Temporal Incision And Skin Take Out In The Vertical Facelift And Lateral Brow Lift Procedures -- Short Scar Facelift With Extended SMAS/Platysma Dissection And Limited Skin Undermining High SMAS Facelift Combined Single Flap Lift Of Jawline, Cheek, And Mid Face -- Extent Of SMAS Advancement In Facelift With Or Without Zygomaticus Major Muscle Release -- A Safe Facelift Using Bony Anatomic Landmarks To Elevate The SMAS -- Deep Plane Facelift -- Endoscopic Forehead Lift -- Minimally Invasive Ciliary-Frontoplasty -- Index.
Format
e-Book
Location
Online
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Advanced surgical facial rejuvenation : art and clinical practice

https://libcat.nshealth.ca/en/permalink/provcat25693
--Heidelberg, Germany: Springer , c2012.
Call Number
WE 705 A244 2012
Location
Halifax Infirmary
Call Number
WE 705 A244 2012
Other Authors
Erian, Anthony
Shiffman, Melvin A
Place of Publication
Heidelberg, Germany
Publisher
Springer
Date of Publication
c2012
Physical Description
740 p.
ISBN
9783642178375
Subjects (MeSH)
Face - surgery
Cosmetic Techniques
Rejuvenation - physiology
Format
Book
Location
Halifax Infirmary
Copies
1
Loan Period
3 weeks
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Advances in Geroscience

https://libcat.nshealth.ca/en/permalink/provcat39908
Felipe Sierra, Ronald Kohanski, editors. (1st ed.) --Cham: Springer , c2016.
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Location
Online
This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a…
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Other Authors
Sierra, Felipe
Kohanski, Ronald
Responsibility
Felipe Sierra, Ronald Kohanski, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xxiii, 622 p. : 39 illus.)
ISBN
9783319232461
9783319232454 (print ed.)
Subjects (MeSH)
Aging - physiology
Chronic Disease
Geriatrics
Risk Factors
Abstract
This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or "healthspan". The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer's diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.
Contents
The Geroscience Hypothesis: Is It Possible to Change the Rate of Aging? / Steven N. Austad -- Etiological Role of Aging in Chronic Diseases: From Epidemiological Evidence to the New Geroscience / Linda P. Fried and Luigi Ferrucci -- The Impact of Aging on Cancer Progression and Treatment / Shenghui He and Norman E. Sharpless -- The Impact of Cancer Treatments on Aging / Changhan Lee and Valter Longo -- Cardiovascular Disease and Aging / Ying Ann Chiao, Edward Lakatta, Zoltan Ungvari, Dao-Fu Dai and Peter Rabinovitch -- The Impact of Aging on Ischemic Stroke / Farida Sohrabji -- Parkinson's Disease and Aging / Julie K. Andersen -- The Role of Aging in Alzheimer's Disease / Geoffrey A. Kerchner and Tony Wyss-Coray -- Aging and the Bone-Muscle Interface / Simon Melov and Clifford J. Rosen -- Osteoporosis and Mechanisms of Skeletal Aging / Julie Glowacki and Tamara Vokes -- Osteoarthritis in the Elderly / Richard F. Loeser and Martin Lotz -- Diabetes and Aging / Nicolas Musi and Andrzej Bartke -- Renal Aging and Transplantation / John P. Higgins and Stuart K. Kim -- Asthma and Aging / Nicola A. Hanania and Paula Busse -- Aging in COPD and Idiopathic Pulmonary Fibrosis / Cecilia Sanchez -- Age-Related Macular Degeneration and Vision Impairment / Jayakrishna Ambati and Charles Wright -- HIV and Aging: Parallels and Synergistic Mechanisms Leading to Premature Disease and Functional Decline / Anna Hearps, Katherine Schafer, Kevin High and Alan Landay -- Pain in the Elderly / Roger B. Fillingim, Dennis C. Turk and Robert P. Yezierski -- The Way Forward / translation: James L. Kirkland.
Format
e-Book
Location
Online
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Advances in Salivary Diagnostics

https://libcat.nshealth.ca/en/permalink/provcat39442
Charles F. Streckfus, editor. --Berlin, Heidelberg: Springer , c2015.
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Location
Online
This book reviews the progress made in salivary diagnostics and identifies the likely direction of future endeavors. After an introductory section describing the histological and anatomical features of the salivary glands and salivary function, salivary collection devices and diagnostic platforms are reviewed. The field of "salivaomics" is then considered in detail, covering, for example, proteomics, the peptidome, DNA and RNA analysis, biomarkers, and methods for biomarker discovery. Salivary …
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Other Authors
Streckfus, Charles F
Responsibility
Charles F. Streckfus, editor
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xiii, 204 p. : 48 illus., 38 illus. in color)
ISBN
9783662453995
9783662453988 (print ed.)
Subjects (MeSH)
Biomarkers
Clinical Chemistry Tests
Pathologic Processes - diagnosis
Saliva - physiology
Salivary Glands
Abstract
This book reviews the progress made in salivary diagnostics and identifies the likely direction of future endeavors. After an introductory section describing the histological and anatomical features of the salivary glands and salivary function, salivary collection devices and diagnostic platforms are reviewed. The field of "salivaomics" is then considered in detail, covering, for example, proteomics, the peptidome, DNA and RNA analysis, biomarkers, and methods for biomarker discovery. Salivary diagnostics for oral and systemic diseases are thoroughly discussed, and the role of salivary gland tissue engineering for future diagnostics is explored. The book closes by considering legal issues and barriers to salivary diagnostic development. Advances in Salivary Diagnostics will be an informative and stimulating reference for both practitioners and students.
Contents
1 Introduction -- 2 The History of Salivary Diagnostics -- 3 Saliva Collection Devices and Diagnostic Platforms -- 4 Salivary Omics -- 5 Salivary Diagnostics and the Oral Microbiome -- 6 Development of Nanoparticle- Enabled Protein Biomarker Discovery: Implementation for Saliva-Based Traumatic Brain Injury Detection -- 7 Saliva Diagnostics for Oral Diseases -- 8 Salivary Gland Tissue Engineering and Future Diagnostics -- 9 Using Saliva Secretions to Model Disease Progression.
Format
e-Book
Location
Online
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Agache’s Measuring the Skin

https://libcat.nshealth.ca/en/permalink/provcat44559
Philippe Humbert, Ferial Fanian, Howard Maibach, Pierre Agache, editors. --Cham: Springer , c2017.
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Location
Online
Since the first edition of this book was published in 2004, to much acclaim, the pace of innovation in the field of skin metrology has increased and various new technologies have become available. This new, revised edition of Measuring the Skin reflects these advances by presenting the current theory and practice of noninvasive investigation and measurement of the skin and its appendices in health and disease. The first, extensive part of the book is devoted to the physiology and metrology of t…
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Other Authors
Humbert, Philippe
Fanian, Ferial
Maibach, Howard
Agache, Pierre
Responsibility
Philippe Humbert, Ferial Fanian, Howard Maibach, Pierre Agache, editors
Alternate Title
Measuring the skin
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2017
Physical Description
1 online resource (approx. 1000 p.)
Series Title
Springer reference
ISBN
9783319265940
Subjects (MeSH)
Dermatology
Skin - anatomy & histology
Skin - physiology
Specialty
Dermatology
Notes
"Living reference work."
Abstract
Since the first edition of this book was published in 2004, to much acclaim, the pace of innovation in the field of skin metrology has increased and various new technologies have become available. This new, revised edition of Measuring the Skin reflects these advances by presenting the current theory and practice of noninvasive investigation and measurement of the skin and its appendices in health and disease. The first, extensive part of the book is devoted to the physiology and metrology of the various structural components of the skin. Skin functions and their measurement are then discussed in detail, with sections on mechanical protection, photoprotection, barrier function, immune function, thermoregulation, and sensory function. In addition, careful consideration is given to skin disease rating and skin maps, and a unique list of physical and biological constants and units is provided. Not only is Measuring the Skin the first comprehensive, practical handbook in this domain – it will also serve as a manual of skin physiology and collates anatomical, functional, and physical quantitative data that would otherwise be arduous to retrieve because of their dispersal throughout the literature. It will prove a valuable resource for dermatologists, cosmetologists, bioengineers, physiologists, pharmacists, and all others who deal with the skin in their work.
Format
e-Book
Publication Type
Encyclopedia
Location
Online
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Age-Related Changes of the Human Eye

https://libcat.nshealth.ca/en/permalink/provcat29975
edited by Carlo A. P. Cavallotti, Luciano Cerulli. --Totowa, NJ: Humana Press , c2008.
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Location
Online
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Author
Cavallotti, Carlo A. P
Other Authors
Cerulli, Luciano
Responsibility
edited by Carlo A. P. Cavallotti, Luciano Cerulli
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2008
Series Title
Aging medicine
ISBN
9781597455077
Subjects (MeSH)
Aging - physiology
Eye Diseases - physiopathology
Subjects (LCSH)
Geriatrics
Ophthalmology
Format
e-Book
Location
Online
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Aging and heart failure : mechanisms and management

https://libcat.nshealth.ca/en/permalink/provcat33590
Bodh I. Jugdutt, editor. --New York: Springer , c2014.
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Location
Online
This book synthesizes the major research advances in molecular, biochemical, and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactio…
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Other Authors
Jugdutt, Bodh I
Responsibility
Bodh I. Jugdutt, editor
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource
ISBN
9781493902682 (electronic bk.)
9781493902675
Subjects (MeSH)
Aging - physiology
Heart Failure
Subjects (LCSH)
Heart failure
Older people - Medical care
Abstract
This book synthesizes the major research advances in molecular, biochemical, and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactions in the aging population with heart failure; changes in the heart that accompany advancing age from humans to molecules; aging-associated alterations in myocardial inflammation and fibrosis; and aging-related changes in mitochondrial function and implications for heart failure therapy. The book succinctly summarizes the large volume of data on these key topics and highlights novel pathways that need to be explored. Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists, and internists.
Contents
Changing Demographics of the Aging Population with Heart Failure and Implications for Therapy -- Biology of Aging and Implications for Heart Failure Therapy and Prevention -- Hypertension and Prevention of Diastolic Heart Failure in the Aging Population -- Aging and Optimal Therapy of Systolic Heart Failure in the Elderly -- Atrial Fibrillation and Heart Failure in the Aging Population -- Optimizing Therapy of Heart Failure in the Aging Population with Monitoring in Clinics -- Cardiac Alterations in Aging, Hypertension, and Diastolic Heart Failure -- Polypharmacy and Adverse Drug Reactions in the Aging Population with Heart Failure -- Age-Related Changes in Vascular Biology and Implications for Heart Failure Therapy in the Aging Population -- Biomarkers and Optimal Management of Heart Failure in the Aging Population -- Benefits of Exercise in the Elderly -- The RAAS in Heart Failure: An Update on Clinical Trials and Opportunities for Therapy -- Aging and Diastolic Dysfunction: The Interplay of Inflammation and Extracellular Matrix Regulation -- Reperfusion and Vasodilator Therapy in Elderly Patients with STEMI and Heart Failure: Improving Outcomes -- Erythropoietin Therapy for Heart Failure -- Role of Resistin in Heart Failure in the Elderly -- Role of Coronary Artery Calcium in Cardiovascular Risk Stratification and Management in the Aging Population -- Aging and Remodeling of the RAS and RAAS and Related Pathways: Implications for Heart Failure Therapy -- Aging and Right Ventricular Failure from Pulmonary Hypertension: Effect of Right Ventricular and Pulmonary Artery Remodeling -- Aging and Right Ventricular Failure from Pulmonary Hypertension: Effect of Right Ventricular and Pulmonary Artery Remodeling -- Biomarkers of Cardiovascular Aging -- Changes in the Heart That Accompany Advancing Age: Humans to Molecules -- Aging-Related Changes in Cell Death and Cell Survival Pathways and Implications for Heart Failure Therapy -- Aging-Related Changes in Telomeres and Telomerases and Implications for Heart Failure Therapy -- Aging-Associated Alterations in Myocardial Inflammation and Fibrosis: Pathophysiological Perspectives and Clinical Implications -- Aging-Related Changes in Extracellular Matrix: Implications for Ventricular Remodeling Following Myocardial Infarction -- Calcium-Handling Defects and Changes in Cardiac Function in the Aging Heart -- Integrins: Implications for Aging in Heart Failure Therapy -- Adipokines as Novel Biomarkers in Aging and Heart Failure -- Aging-Related Changes in Cellular and Molecular Mechanisms of Postinfarction Remodeling: Implications for Heart Failure Therapy -- Aging-Related Changes in Mitochondrial Function and Implication for Heart Failure Therapy -- Regulation of SERCA Via Oxidative Modifications: Implications for the Pathophysiology of Diastolic Dysfunction in the Aging Heart -- SMP30 and Aging-Related Cardiac Remodeling and Heart Failure.
Format
e-Book
Location
Online
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Aging and the heart : A Post-Genomic View

https://libcat.nshealth.ca/en/permalink/provcat28046
by José Marín-García, Michael J. Goldenthal, Gordon W. Moe. --Boston, MA: Springer Science+Business Media , c2008.
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Location
Online
Available Online
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Author
Marín-García, José
Other Authors
Goldenthal, Michael J
Moe, Gordon W
Responsibility
by José Marín-García, Michael J. Goldenthal, Gordon W. Moe
Place of Publication
Boston, MA
Publisher
Springer Science+Business Media
Date of Publication
c2008
ISBN
9780387740720
Subjects (MeSH)
Aging - physiology
Cardiovascular Diseases - genetics
Cardiovascular Diseases - physiopathology
Subjects (LCSH)
Cardiology
Geriatrics
Format
e-Book
Location
Online
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