This book is a guide to new and emerging PET technology, instrumentation, and its place in clinical practice. PET technology is currently moving from the conventional photomultiplier tube (PMT) detector based PET to the new generation, solid state light sensor detector. This is a technological leap and holds significant implications for the use of PET imaging. This book introduces and describes the emerging and new generation of PET instrumentations and technologies across manufactures, focusin…
This book provides up-to-date guidance on the use of FDG PET to assess the biological activity and treatment response of a wide range of malignancies, including, for example, lung cancer, breast cancer, head and neck cancer, gastrointestinal cancer, and malignant lymphoma. In the era of precision medicine, numerous new anticancer agents, such as molecular targeted agents and immune checkpoint inhibitors, have been developed to improve outcomes in cancer patients. FDG PET plays a key role in eva…
This atlas showcases cross-sectional anatomy for the proper interpretation of images generated from PET/MRI, PET/CT, and SPECT/CT applications. Hybrid imaging is at the forefront of nuclear and molecular imaging and enhances data acquisition for the purposes of diagnosis and treatment. Simultaneous evaluation of anatomic and metabolic information about normal and abnormal processes addresses complex clinical questions and raises the level of confidence of the scan interpretation. Extensively il…
This new atlas, the fourth of a successful series, is a completely revised and updated edition of a previously published FDG PET-CT atlas. In the past few years, considerable progress has been made in the field of PET-CT imaging, and this new edition takes full account of these recent developments. Furthermore, its educational mission has been broadened: beyond serving as a straightforward guide to FDG PET-CT imaging it now encompasses the integrative use of contrast-enhanced CT and MRI. The ne…
This atlas is a case-based guide to the interpretation of FDG PET-CT images in clinical scenarios faced by physicians during the routine practice of oncology. The book aims to help the practitioner to overcome diagnostic dilemmas through familiarization with the physiologic distribution of FDG, normal variants, and benign findings. It includes a rich variety of atypical incidental findings which are rarely seen but may give rise to inconclusive reports. The main focus, however, is the imaging o…
This richly illustrated book presents the pediatric applications of PET/CT in the full range of scenarios frequently encountered in a professional setting. It opens with a thorough introduction covering the fundamental science and the clinical basis for use of PET/CT in this age group. Pitfalls and artifacts are examined, and normal variations and benign findings are carefully described. Each subsequent chapter addresses the role of PET/CT with different radiopharmaceuticals in the evaluation a…
This new project on PET/MR imaging in oncology includes digital interactive software matching the cases in the book. The interactive version of the atlas is based on the latest web standard, HTML5, ensuring compatibility with any computer operating system as well as a dedicated version for Apple iPad and iPhone. The book opens with an introduction to the principles of hybrid imaging that pays particular attention to PET/MR imaging and standard PET/MR acquisition protocols. A wide range of illus…
This atlas is a concise but comprehensive guide to the diverse patterns of response to immunotherapy as observed on Positron Emission Tomography/Computed Tomography (PET/CT) and other conventional imaging modalities, including CT and Magnetic Resonance Imaging (MRI). The purpose for this publication is to fill the gap between the growing clinical relevance and utilization of immunotherapy in medical oncology, mainly based on checkpoint inhibitors, and the need for experienced imagers with relia…
The horizons of sophisticated imaging have expanded with the use of combined positron emission tomography (PET) and computed tomography (CT). PET-CT has revolutionized medical imaging by adding anatomic localization to functional imaging, thus providing physicians with information that is vital for the accurate diagnosis and treatment of pathologies. Since the integration of PET and CT several years ago, PET/CT procedures are now routine at leading medical centers throughout the world. This has…
This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceutical…
This classic text presents the basic concepts of positron emission tomography (PET). Topics include basic physics of PET imaging; scanning systems; data acquisition; storage and display; PET radionuclides and radiopharmaceuticals; regulatory policies for PET radiopharmaceuticals; reimbursement for PET procedures; and performance of PET studies. The Third Edition is thoroughly updated and includes information on magnetic resonance scanners; PET/MR imaging; new positron emitting radionuclides wit…
Divided into two parts, this book discusses various aspects of bone SPECT-CT of ankle and foot. The first part is dedicated to foot and ankle pathology and concisely presents those disorders most frequently detected with a bone scan. The authors also describe common pathologies that cannot be diagnosed with bone scans, such as Morton's neuroma, but which nuclear physicians need to recognize. Orthopedic surgeons' expectancies are highlighted and several bone scan studies of clinical interest are…
Clinical PET and PET/CT, 2nd edition presents a valuable overview of the basic principles and clinical applications of PET and PET/CT. Emphasis is placed on the familiarization of normal distribution, artifacts, and common imaging agents such as FDG in conjunction with CT, MRI, and US to establish the clinical effectiveness of PET and PET/CT. Practical information about updated PET and PET/CT scanners, imaging processing, correlation, and quantification of PET and PET/CT measurements is also pr…
FDG PET/CT has rapidly emerged as an invaluable combined imaging modality that can identify tumors on the basis of not only anatomical alterations but also metabolic activity, thus allowing the detection of lesions that would otherwise be too small to distinguish. This book, comprising a collection of images from oncology cases, is organized according to the role of FDG PET/CT in the evaluation and management of oncology patients, and only secondarily by organ or tumor entity. In this way, it …
This book presents a comprehensive overview of current state-of-the-art clinical physiological imaging of brain tumors. It focuses on the clinical applications of various modalities as they relate to brain tumor imaging, including techniques such as blood oxygen level dependent functional magnetic resonance imaging, diffusion tensor imaging, magnetic source imaging/magnetoencephalography, magnetic resonance perfusion imaging, magnetic resonance spectroscopic imaging, amide proton transfer imagi…
Nuclear cardiology procedures have been a mainstay in non-invasive testing for the diagnosis and risk stratification of coronary artery disease for many years. Although a mature field with a multitude of clinical applications, the advances in agents and imaging procedures have been remarkable and important to document. Handbook of Nuclear Cardiology: Cardiac SPECT and Cardiac PET reviews the important indications for nuclear cardiology procedures, and provides a description of the procedures th…