An Information Technology Framework for Predictive, Preventive and Personalised Medicine : A Use-Case with Hepatocellular Carcinoma
https://libcat.nshealth.ca/en/permalink/provcat39137
Leonard Berliner, Heinz U. Lemke, editors.
--Cham:
Springer
, c2015.
- Available Online
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- Location
- Online
This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact tha…
- Available Online
- View e-Book
- Other Authors
- Berliner, Leonard
- Lemke, Heinz U
- Responsibility
- Leonard Berliner, Heinz U. Lemke, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xx, 130 p. : 23 illus., 15 illus. in color)
- Series Vol.
- v. 8
- ISBN
- 9783319121666
- 9783319121659 (print ed.)
- ISSN
- 2211-3495
- Subjects (MeSH)
- Carcinoma, Hepatocellular - therapy
- Medical Informatics - methods
- Precision Medicine - methods
- Preventive Medicine - methods
- Abstract
- This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.
- Contents
- Preface -- Introduction -- The Digital Patient Model and Model Guided Therapy -- Hepatocellular Carcinoma and Patient Assessment -- Imaging in Hepatocellular Carcinoma: Radiologic Assessment -- Imaging in Hepatocellular Carcinoma: PET/CT -- Personalized Chemotherapy for Hepatocellular Carcinoma -- Surgical Treatment for Hepatocellular Carcinoma -- Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Technologies -- Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Therapies -- Minimally Invasive Therapies for Hepatocellular Cancer: Catheter-Directed Therapies -- Radiation Oncology in the Treatment of Hepatocellular Carcinoma -- Design of an IT System for Hepatocellular Carcinoma -- Outlook and Expert Recommendations for Predictive, Preventive and Personalized Medicine and Hepatocellular Carcinoma.
- Format
- e-Book
- Location
- Online
Genomic and precision medicine : cardiovascular disease
https://libcat.nshealth.ca/en/permalink/provcat41104
edited by Geoffrey S. Ginsburg, Huntington F. Willard.
(3rd ed.)
--London, UK:
Elsevier
, c2018.
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Genomic and Precision Medicine: Cardiovascular Disease, Third Edition, focuses on the applications of genome discovery on the broad spectrum of cardiovascular disorders. Each chapter is organized for the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.
- Available Online
- View e-Book
- Other Authors
- Ginsburg, Geoffrey S
- Responsibility
- edited by Geoffrey S. Ginsburg, Huntington F. Willard
- Edition
- 3rd ed.
- Place of Publication
- London, UK
- Publisher
- Elsevier
- Date of Publication
- c2018
- Physical Description
- 1 online resource, 336 p.
- ISBN
- 9780128018125
- Specialty
- Cardiology
- Genetics, Medical
- Precision Medicine
- Abstract
- Genomic and Precision Medicine: Cardiovascular Disease, Third Edition, focuses on the applications of genome discovery on the broad spectrum of cardiovascular disorders. Each chapter is organized for the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Genomic and precision medicine : foundations, translation, and implementation
https://libcat.nshealth.ca/en/permalink/provcat41031
edited by Geoffrey S. Ginsburg, Huntington F. Willard.
(3rd ed.)
--London, UK:
Elsevier
, c2017.
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- Registration required for PDF access.
- Location
- Online
Genomic and Precision Medicine: Foundations, Translation, and Implementation highlights the various points along the continuum from health to disease where genomic information is impacting clinical decision-making and leading to more personalization of health care.
- Available Online
- View e-Book
- Other Authors
- Ginsburg, Geoffrey S
- Responsibility
- edited by Geoffrey S. Ginsburg, Huntington F. Willard
- Edition
- 3rd ed.
- Place of Publication
- London, UK
- Publisher
- Elsevier
- Date of Publication
- c2017
- Physical Description
- 1 online resource, 398 p.
- ISBN
- 9780128006818
- Abstract
- Genomic and Precision Medicine: Foundations, Translation, and Implementation highlights the various points along the continuum from health to disease where genomic information is impacting clinical decision-making and leading to more personalization of health care.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Genomic and precision medicine : foundations, translation, and implementation
https://libcat.nshealth.ca/en/permalink/provcat50741
Ginsburg, Geoffrey.
(3rd ed.)
--Philadelphia, PA:
Elsevier
, 2017.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Ginsburg, Geoffrey
- Edition
- 3rd ed.
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- 2017
- ISBN
- 9780128006818
- Notes
- Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
- Format
- e-Book
- Location
- Online
Genomic and precision medicine : infectious and inflammatory disease
https://libcat.nshealth.ca/en/permalink/provcat43986
edited by Geoffrey S. Ginsburg, Huntington F. Willard.
(3rd ed.)
--London, UK:
Academic Press
, c2019.
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- Online
Genomic and Precision Medicine: Inflammation and Metabolic Disorders, Third Edition, provides current clinical solutions on the application of genome discovery on a broad spectrum of disease categories in IMD - including asthma, obesity and multiple sclerosis. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies, along with information on a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precisi…
- Available Online
- View e-Book
- Other Authors
- Ginsburg, Geoffrey S.
- Responsibility
- edited by Geoffrey S. Ginsburg, Huntington F. Willard
- Edition
- 3rd ed.
- Place of Publication
- London, UK
- Publisher
- Academic Press
- Date of Publication
- c2019
- Physical Description
- 1 online resource
- ISBN
- 9780128014967
- Specialty
- Genetics, Medical
- Precision Medicine
- Abstract
- Genomic and Precision Medicine: Inflammation and Metabolic Disorders, Third Edition, provides current clinical solutions on the application of genome discovery on a broad spectrum of disease categories in IMD - including asthma, obesity and multiple sclerosis. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies, along with information on a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Genomic and precision medicine : infectious and inflammatory disease
https://libcat.nshealth.ca/en/permalink/provcat50739
Ginsburg, Geoffrey S.
(3rd ed.)
--London, England:
Academic Press
, 2019.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Ginsburg, Geoffrey S.
- Other Authors
- Willard, Huntington F.
- Tsalik, Ephraim L.
- Woods, Christopher W.
- Edition
- 3rd ed.
- Place of Publication
- London, England
- Publisher
- Academic Press
- Date of Publication
- 2019
- ISBN
- 9780128014967
- Notes
- Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
- Format
- e-Book
- Location
- Online
Genomic and precision medicine : primary care
https://libcat.nshealth.ca/en/permalink/provcat41032
edited by Sean P. David.
(3rd ed.)
--London, UK:
Elsevier
, c2017.
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- Online
Genomic and Precision Medicine: Primary Care, Third Edition is an invaluable resource on the state-of-the-art tools, technologies and policy issues that are required to fully realize personalized health care in the area of primary care.
- Available Online
- View e-Book
- Other Authors
- David, Sean P
- Responsibility
- edited by Sean P. David
- Edition
- 3rd ed.
- Place of Publication
- London, UK
- Publisher
- Elsevier
- Date of Publication
- c2017
- Physical Description
- 1 online resource, 370 p.
- ISBN
- 9780128006856
- Abstract
- Genomic and Precision Medicine: Primary Care, Third Edition is an invaluable resource on the state-of-the-art tools, technologies and policy issues that are required to fully realize personalized health care in the area of primary care.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Genomic and precision medicine : primary care
https://libcat.nshealth.ca/en/permalink/provcat50742
David, Sean.
(3rd ed.)
--Philadelphia, PA:
Elsevier
, 2017.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- David, Sean
- Edition
- 3rd ed.
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- 2017
- ISBN
- 9780128006856
- Notes
- Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
- Format
- e-Book
- Location
- Online
Genomic Medicine : A Practical Guide
https://libcat.nshealth.ca/en/permalink/provcat44958
Laura J. Tafe, Maria E. Arcila, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest…
- Available Online
- View e-Book
- Other Authors
- Tafe, Laura J.
- Arcila, Maria E.
- Responsibility
- Laura J. Tafe, Maria E. Arcila, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (x, 325 p.) : 21 illus., 20 illus. in color
- ISBN
- 9783030229221
- 9783030229214 (Print ed.)
- 9783030229238 (Print ed.)
- Subjects (MeSH)
- Biomarkers, Tumor
- Molecular Diagnostic Techniques
- Pathology, Molecular
- Precision Medicine - methods
- Specialty
- Genetics, Medical
- Abstract
- The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest in molecular pathology and biomarkers. The book covers many aspects of molecular diagnostics, from techniques to applications and comprehensive summaries of the current molecular biomarkers of critical importance in solid and liquid tumors. Attention is also specifi cally devoted to bioinformatics and next generation sequencing, as well as pre-analytical issues that must be considered for accurate interpretation of molecular results in the context of overall patient care. This text focuses on clinical utility and validity and serves as an “owner’s manual” in Genomic Diagnostics for the practicing pathologist, pathology fellows and residents and other health care providers. Physicians will find this book invaluable as a quick reference for current molecular testing modalities and guidelines, tumor board preparation, deciding which test to order and interpreting genomic laboratory results. In addition, it is an accessible for trainees as a board review preparation reference.
- Contents
- Part I. General Concepts -- Pre-Analytics, Current Testing Technologies, and Limitations of Testing -- Next Generation Sequencing -- Cell-Free DNA Testing -- Role of Bioinformatics in Molecular Medicine -- Interpreting Genomic Reports -- Part II. Applications in Solid Tumors -- Lung Carcinoma -- GI including GIST -- Breast -- Genitourinary Tumors -- Gynecologic Malignancies -- Sarcomas -- Salivary Gland Carcinomas -- Sinonasal Carcinomas -- Part III. Applications in Hematopathology -- Acute Myeloid Neoplasms -- Chronic Myeloid Neoplasms -- Lymphomas.
- Format
- e-Book
- Location
- Online
Oncology in the Precision Medicine Era : Value-Based Medicine
https://libcat.nshealth.ca/en/permalink/provcat44847
Ravi Salgia, editor.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This volume comprehensively reviews oncology in the precision medicine era of personalized care, latest developments in the field, and indications and clinical trials for the treatment of cancer with targeted therapies, immunotherapy, and epigenetic modulators. It thoroughly addresses concerns of various types of cancers including cancers of the head and neck, lung, colon, esophagus, bladder, pancreas, and breast; melanoma; multiple myeloma; hepatocellular carcinoma; renal cell carcinoma; and s…
- Available Online
- View e-Book
- Other Authors
- Salgia, Ravi
- Responsibility
- Ravi Salgia, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xiii, 351 p.) : 28 illus., 16 illus. in color
- ISBN
- 9783030314712
- 9783030314705 (Print ed.)
- 9783030314729 (Print ed.)
- 9783030314736 (Print ed.)
- Subjects (MeSH)
- Neoplasms - therapy
- Precision Medicine - methods
- Specialty
- Medical Oncology
- Precision Medicine
- Abstract
- This volume comprehensively reviews oncology in the precision medicine era of personalized care, latest developments in the field, and indications and clinical trials for the treatment of cancer with targeted therapies, immunotherapy, and epigenetic modulators. It thoroughly addresses concerns of various types of cancers including cancers of the head and neck, lung, colon, esophagus, bladder, pancreas, and breast; melanoma; multiple myeloma; hepatocellular carcinoma; renal cell carcinoma; and sarcomas. It is organized and written in a format that is easy to follow for both clinicians and non-clinical scientists interested in personalized medicine. Chapters cover the identification of the clinical problem and summary of recent findings, tumor biology and heterogeneity, genomics, examples of simple and complex cases, biological pathways, future clinical trials, and financial considerations. Oncology in the Precision Medicine Era: Value-Based Medicine will serve as a useful resource for medical oncologists and healthcare providers tailoring medicine to the needs of the individual patient, from prevention and diagnosis to treatment and follow up.
- Contents
- Healthcare Perspective -- Lung Cancer -- Esophageal and Gastric Cancer- Sarcomas -- Multiple Myeloma -- Pancreatic Cancer -- Colon Cancer -- Renal Cell Carcinoma -- Prostate Cancer -- Molecular Testing in Ovarian Cancer: Recommendations and Treatment Considerations -- Genomic Cancer Risk Assessment -- Triple-Negative Breast Cancer -- Melanoma -- Digital Patient Engagement and Social Media -- Hepatocellular Carcinoma -- Treatment Strategies in Head and Neck Cancer -- Primary Central Nervous System Tumors -- Lymphoma.
- Format
- e-Book
- Location
- Online
Personalized and Precision Medicine Informatics : A Workflow-Based View
https://libcat.nshealth.ca/en/permalink/provcat44991
Terrence Adam, Constantin Aliferis, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book adopts an integrated and workflow-based treatment of the field of personalized and precision medicine (PPM). Outlined within are established, proven and mature workflows as well as emerging and highly-promising opportunities for development. Each workflow is reviewed in terms of its operation and how they are enabled by a multitude of informatics methods and infrastructures. The book goes on to describe which parts are crucial to discovery and which are essential to delivery and how e…
- Available Online
- View e-Book
- Other Authors
- Adam, Terrence
- Aliferis, Constantin
- Responsibility
- Terrence Adam, Constantin Aliferis, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xvi, 349 p.) : 67 illus., 45 illus. in color
- Series Title
- Health informatics
- ISBN
- 9783030186265
- 9783030186258 (Print ed.)
- 9783030186272 (Print ed.)
- 9783030186289 (Print ed.)
- ISSN
- 1431-1917
- Subjects (MeSH)
- Medical Informatics
- Precision Medicine - methods
- Specialty
- Medical Informatics
- Precision Medicine
- Abstract
- This book adopts an integrated and workflow-based treatment of the field of personalized and precision medicine (PPM). Outlined within are established, proven and mature workflows as well as emerging and highly-promising opportunities for development. Each workflow is reviewed in terms of its operation and how they are enabled by a multitude of informatics methods and infrastructures. The book goes on to describe which parts are crucial to discovery and which are essential to delivery and how each of these interface and feed into one-another. Personalized and Precision Medicine Informatics provides a comprehensive review of the integrative as well as interpretive nature of the topic and brings together a large body of literature to define the topic and ensure that this is the key reference for the topic. It is an unique contribution that is positioned to be an essential guide for both PPM experts and non-experts, and for both informatics and non-informatics professionals.
- Contents
- Part I. Introduction -- 1. Birth of a Discipline: Personalized and Precision Medicine (PPM) Informatics -- Part II. Classical PPM -- 2. Clinical Risk Assessment and Prediction -- 3. Principles of Guideline-Driven PPM Informatics -- 4. Genetic Counseling at the Intersection of Clinical Genetics and Informatics -- 5. Fundamentals of Drug Metabolism and Pharmacogenomics Within a Learning Healthcare System Workflow Perspective -- 6. The Growing Medication Problem: Perspective from Industry -- Part III. Emerging PPM -- 7. Risk Stratification and Prognosis Using Predictive Modelling and Big Data Approaches -- 8 Informatics Methods for Molecular Profiling 9. Constructing Software for Cancer Research in Support of Molecular PPM -- 10. Platform-Independent Gene-Expression Based Classification-System for Molecular Sub-typing of Cancer -- 11. Tumor Sequencing: Enabling Personalized Targeted Treatments with Informatics -- 12. Largescale Distributed PPM Databases: Harmonizing and Standardizing PPM Cohorts and Clinical Genomics Data Sharing Consortia -- 13. Redefining Disease Using Informatics -- 14 Pragmatic Trials and New Informatics Methods to Supplement or Replace Phase IV Trials -- 15. Precision Trials Informatics -- 16. Informatics for a Precision Learning Healthcare System -- Part IV. Integrative Informatics for PPM -- 17. The Genomic Medical Record and Omic Ancillary Systems -- 18. Generalizable Architectures and Principles of Informatics for Scalable Personalized and Precision Medicine (PPM) Decision Support -- 19. Building Comprehensive Enterprise-Scale PPM Clinical Informatics Capability and Capacity -- 20. Personalized and Precision Medicine Informatics Education -- Part V. Conclusion -- 21. The Landscape of PPM Informatics and the Future of Medicine.
- Format
- e-Book
- Location
- Online
Personalized, Evolutionary, and Ecological Dermatology
https://libcat.nshealth.ca/en/permalink/provcat40297
Robert A. Norman, editor.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book discusses the potential to enhance the dermatology profession's valuable pattern recognition, diagnostic, and treatment skills via the evolution of modern medical techniques, including the advent of personalized medicine and genomics. These are now easily accessible and enable the customization of healthcare using molecular analysis to influence medical decisions, practices, and therapies for the individual patient. The evolution of the skin, and the manner in which dermatological con…
- Available Online
- View e-Book
- Other Authors
- Norman, Robert A
- Responsibility
- Robert A. Norman, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xiv, 142 p. : 22 illus., 20 illus. in color)
- ISBN
- 9783319410883
- 9783319410869 (print ed.)
- Subjects (MeSH)
- Biological Evolution
- Dermatology - methods
- Environment
- Genomics
- Precision Medicine - methods
- Skin Diseases
- Abstract
- This book discusses the potential to enhance the dermatology profession's valuable pattern recognition, diagnostic, and treatment skills via the evolution of modern medical techniques, including the advent of personalized medicine and genomics. These are now easily accessible and enable the customization of healthcare using molecular analysis to influence medical decisions, practices, and therapies for the individual patient. The evolution of the skin, and the manner in which dermatological conditions are described and managed, reveals the need to consider many aspects on a personal level. In addition, as more is understood about the biology of the skin and how the introduction of new antibiotics, biologics, and other therapies affect our skin's ecological balance, this book aims to create a heightened sense of the importance and offerings of ecological dermatology. Personalized, Evolutionary, and Ecological Dermatology brings together the major biological topics and succinctly summarizes how the addition of personalized medicine with an evolutionary and ecological perspective, if used carefully and ethically, can assist dermatologists in becoming more successful treatment providers.
- Contents
- 1. Genetic Testing and Personalized Medicine in Dermatology -- 2. Genetic and Epigenetic Testing in Integrative Dermatology -- 3. Forensic Dermatology -- 4. Dermatopathology, Genetics, and Intergenerational Dermatology -- 5. The Evolution of Human Skin and the Thousands of Species It Sustains, with Ten Hypothesis of Relevance to Doctors -- 6. What’s New in Dermatopathology? -- 7. Genomics, Ethics, and Compliance -- 8. Genetics, Nutrition, and Skin -- 9. Ecological Dermatology -- 10. Skin Color -- 11. Genome and Skin Cancer.
- Format
- e-Book
- Location
- Online
Personalized Management of Gastric Cancer : Translational and Precision Medicine
https://libcat.nshealth.ca/en/permalink/provcat41986
Jia Wei, Baorui Liu, editors.
--Singapore:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book offers essential information on basic and translational research in gastric cancer, while also illustrating potential opportunities for its application in clinical practice. Gastric cancer is the fourth-most-common cancer globally and the second-leading cause of cancer deaths. It is known to be a heterogeneous disease with varied responses to one-size-fits-all treatments. Expanding our knowledge of cancer cell genetics may help us to explore more effective treatments in gastric cancer…
- Available Online
- View e-Book
- Other Authors
- Wei, Jia
- Liu, Baorui
- Responsibility
- Jia Wei, Baorui Liu, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (viii, 227 pages) : 34 illus., 32 illus. in color
- ISBN
- 9789811039782
- 9789811039775 (print ed.)
- Subjects (MeSH)
- Immunotherapy - methods
- Molecular Targeted Therapy - methods
- Nanomedicine - methods
- Precision Medicine - methods
- Stomach Neoplasms - therapy
- Abstract
- This book offers essential information on basic and translational research in gastric cancer, while also illustrating potential opportunities for its application in clinical practice. Gastric cancer is the fourth-most-common cancer globally and the second-leading cause of cancer deaths. It is known to be a heterogeneous disease with varied responses to one-size-fits-all treatments. Expanding our knowledge of cancer cell genetics may help us to explore more effective treatments in gastric cancer. The research on molecular mechanisms and its clinical applications, both presented here, will help readers gain an in-depth understanding of gastric cancer and its effective treatment. The book's four sections cover personalized medicine, precise regional therapy, immunotherapy and nanomedicine in gastric cancer. Each part presents the state of art, recent advances and the authors' experiences. Moreover, several interesting cases are described to demonstrate how gastric cancer patients benefit from translational research. This informative and attractively presented book on precision treatment in gastric cancer, including experimental findings and clinical treatment options, offers a valuable resource for oncologists and graduate students working in the field of gastric cancer. Jia Wei, MD, PhD, is an associate professor at Nanjing University and the vice director of Clinical Cancer Institute of Nanjing University. She is now working as an oncologist in the Comprehensive Cancer Center, Affiliated Drum Tower Hospital to Medical School of Nanjing University. Baorui Liu, MD, PhD, is a professor at Nanjing University and director of the Clinical Cancer Institute of Nanjing University. He is also the director of the Comprehensive Cancer Center of Drum Tower Hospital.
- Contents
- Part I: Personalized Therapy in Gastric Cancer -- Molecular pathology of hereditary gastric cancer -- Genetics and molecular signature of gastric cancer -- Circulating tumor cells in gastric cancer -- Customized chemotherapy in advanced gastric cancer -- Targeted therapy in advanced gastric cancer -- Part II: Precision Regional Therapy in Gastric Cancer -- Laparoscopic surgery and robotic surgery -- Radiotherapy in peritoneal metastatic gastric cancer -- Personalized intraperitoneal strategy in gastric cancer -- Part III: Immunotherapy -- Immune checkpoint blockade therapy of gastric cancer -- Adoptive cell therapy of gastric cancer -- Combinational immunotherapy of gastric cancer -- Part IV: Use of Nanomedicine in the Diagnosis and Treatment of Gastric Cancer -- Use of Nanomedicine in the diagnosis of gastric cancer -- Systemic drug delivery -- Local drug delivery -- Drug delivery in synergistic combination with other treatments.
- Format
- e-Book
- Location
- Online
Personalized Oral Health Care : From Concept Design to Clinical Practice
https://libcat.nshealth.ca/en/permalink/provcat39387
Peter J. Polverini, editor.
(1st ed.)
--Cham:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
This book provides an overview of the evolving oral health care environment and describes an array of technologies, under development or already applied in practice, that are impacting on risk assessment, diagnosis, and therapy. Detailed consideration is also devoted to personalized health insurance in the new environment, the impact of personalized health care on the economics of health care, and the consequences for the global diagnostic market place and improved access to care. The changes i…
- Available Online
- View e-Book
- Other Authors
- Polverini, Peter J
- Responsibility
- Peter J. Polverini, editor
- Edition
- 1st ed.
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xiii, 158 p. : 26 illus.)
- ISBN
- 9783319232973
- 9783319232966 (print ed.)
- Subjects (MeSH)
- Dental Care
- Mouth Diseases - diagnosis
- Mouth Diseases - therapy
- Oral Medicine - trends
- Precision Medicine - methods
- Abstract
- This book provides an overview of the evolving oral health care environment and describes an array of technologies, under development or already applied in practice, that are impacting on risk assessment, diagnosis, and therapy. Detailed consideration is also devoted to personalized health insurance in the new environment, the impact of personalized health care on the economics of health care, and the consequences for the global diagnostic market place and improved access to care. The changes in dental education required to produce dentists better equipped to participate in the new health care environment are examined, and the book concludes by considering key opportunities and challenges.
- Contents
- 1. Personalized Oral Medicine and the Contemporary Health Care Environment -- 2. Genomic Approaches to Disease Diagnosis and Prevention -- 3. Health Information Technology (Health IT): The Future of Personal Medicine -- 4. Biomarkers for Individualized Oral Cancer Therapy -- 5 Clinical Diagnostics and Patient Stratification for Use in the Dental Office -- 6. Metabolomics and Oral Disease Diagnosis -- 7. Genomics of Dental Caries and Caries Risk Assessment -- 8. Personalized Medicine Approaches to the Prevention, Diagnosis, and Treatment of Chronic Periodontitis -- 9. The Brain as a Therapeutic Target in TMD and Orofacial Pain: The Next Frontier in Personalized Pain Medicine and Health Technology -- 10. Preparing the Next Generation of Oral Healthcare Professionals for a Personalized Oral Healthcare Environment -- 11. Policy and Personalized Oral Health Care -- 12. Opportunities and Challenges for the Future of Personalized Oral Healthcare.
- Format
- e-Book
- Location
- Online
Personalized Pathway-Activated Systems Imaging in Oncology : Principal and Instrumentation
https://libcat.nshealth.ca/en/permalink/provcat41977
Tomio Inoue, David Yang, Gang Huang, editors.
--Singapore:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This comprehensive volume covers radiopharmaceuticals developed for pathway-directed systems in imaging and theranostic applications. We now are at the cutting edge of providing personalized treatment with increased use in oncology of these new radiopharmaceuticals. Trends in high-resolution instrumentation development, quality assurance systems and regulatory compliance for radiopharmaceuticals, clinical evaluation of radiopharmaceuticals, and benefits and pitfalls of the current clinical FDG …
- Available Online
- View e-Book
- Other Authors
- Inoue, Tomio
- Yang, David
- Huang, Gang
- Responsibility
- Tomio Inoue, David Yang, Gang Huang, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xii, 243 pages) : 112 illus., 71 illus. in color
- ISBN
- 9789811033490
- 9789811033483 (print ed.)
- Subjects (MeSH)
- Neoplasms - diagnostic imaging
- Positron Emission Tomography Computed Tomography - methods
- Precision Medicine - methods
- Radioactive Tracers
- Radiopharmaceuticals
- Abstract
- This comprehensive volume covers radiopharmaceuticals developed for pathway-directed systems in imaging and theranostic applications. We now are at the cutting edge of providing personalized treatment with increased use in oncology of these new radiopharmaceuticals. Trends in high-resolution instrumentation development, quality assurance systems and regulatory compliance for radiopharmaceuticals, clinical evaluation of radiopharmaceuticals, and benefits and pitfalls of the current clinical FDG PET are discussed. Radiopharmaceuticals are used for diagnosis of diseases of the central nervous and cardiovascular systems and for staging, restaging, and treatment planning for cancers. Nuclear biomarkers allow precise measurement of molecular pathways on a whole-body image upon administration of functional radiolabeled agents, and nuclear imaging agents have potential use in patient selection, pharmacokinetic, dosage-finding, and proof-of-concept studies. Nuclear imaging agents and hybrid instrumentation also provide sensitive and specific answers for differential responsiveness in therapeutic outcome. This book serves as a reference for moving the discovery and development of radiopharmaceuticals from the workbench to clinical applications. It thus benefits not only clinicians but also translational research scientists, molecular biologists, chemists, imaging scientists, pharmaceutical developers, physicists, and support staff.
- Contents
- Part I: Chemical Biology Aspect -- Chapter 1: PET Radiotracers for Tumor Imaging (Ming Rong Zhang) -- Chapter 2. Theranostic tracers for pathway-activated systems in oncology (Lan V. Pham, Jerry L. Bryant, David Yang, and Richard J. Ford) -- Chapter 3. Optimization of Aseptic Production in PET Radiopharmaceuticals for Compliance to the Most Current GMP (Chih-Hao K. Kao) - Part II: Engineering and Instrumentation Aspect -- Chapter 4. OpenPET enabling PET imaging during radiotherapy (Taiga Yamaya and Hideaki Tashima) -- Chapter 5. High Resolution PET/CT development (Wai-Hoi Wong, and Yuxuan Zhang) -- Part III: Social Aspect -- Chapter 6. Ethics, Regulations and Clinical Development of Precision Medicine: Activating with molecular imaging (Chieko Kurihara, and Tomio Inoue) -- Chapter 7. Optical Imaging: How far can we go (Wenbin Ma, Sara Herrera-Rodriguez, and Hector Martinez-Valdez) -- Part IV: Clinic Aspect -- Chapter 8. Applications of UIH High Resolution PET/CT in Zhongshan Hospital (Jun Zhou, Hongcheng Shi) -- Chapter 9. Clinical evaluation of focused high-resolution breast PET (Kanae Kawai Miyake, Yuji Nakamoto) -- Chapter 10. Recent Developments with Large-bore PET/CT (Tomohiro Kaneta, Tomio Inoue) -- Chapter 11. Copper-labeled radiopharmaceuticals in oncology (Hiroaki Kurihara) -- Chapter 12. PET radiopharmaceuticals in oncology beyond FDG (Shao-Li Song, Pan-Li Li, Gang Huang) -- Chapter 13. Molecular Imaging in Oncology: Challenges and Opportunities in 21st Century (Ya-Ming Li, Ya-Ming Li, David J. Yang, and Xue-Na Li) -- Chapter 14. Visualization of Apoptosis: Annexin V imaging (Skye Hsin-Hsien Yeh, Fan-Lin Kong, Ming-Hsien Lin).
- Format
- e-Book
- Location
- Online
Personalized Treatment of Breast Cancer
https://libcat.nshealth.ca/en/permalink/provcat40393
Masakazu Toi, Eric Winer, John Benson, Suzanne Klimberg, editors.
--Tokyo:
Springer Japan
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book deals with the essential factors in the personalization of treatment for primary breast cancer. These include host issues, lymph node surgery, radiation therapy, and preoperative systemic treatment requiring specialized knowledge, multidisciplinary care experience, techniques, and research. Locoregional treatment in conjunction with systemic treatments is another important factor, with options for local therapy significantly affected by genetic BRCA mutation. Axillary treatment issues…
- Available Online
- View e-Book
- Other Authors
- Toi, Masakazu
- Winer, Eric
- Benson, John
- Klimberg, Suzanne
- Responsibility
- Masakazu Toi, Eric Winer, John Benson, Suzanne Klimberg, editors
- Place of Publication
- Tokyo
- Publisher
- Springer Japan
- Date of Publication
- c2016
- Physical Description
- 1 online resource (ix, 388 p. : 71 illus., 52 illus. in color)
- ISBN
- 9784431555520
- 9784431555513 (print ed.)
- Subjects (MeSH)
- Breast neoplasms - therapy
- Precision Medicine - methods
- Abstract
- This book deals with the essential factors in the personalization of treatment for primary breast cancer. These include host issues, lymph node surgery, radiation therapy, and preoperative systemic treatment requiring specialized knowledge, multidisciplinary care experience, techniques, and research. Locoregional treatment in conjunction with systemic treatments is another important factor, with options for local therapy significantly affected by genetic BRCA mutation. Axillary treatment issues have become top priorities in recent primary breast cancer care, and these are highlighted in the book's presentation of technological advances in lymph node mapping and diagnosis, axillary clearance in patients with nodal metastasis, and the role of axillary surgery. Attention is also given to locoregional treatment after preoperative systemic therapy. Because therapeutic impact differs depending upon biological characteristics such as tumor subtype, local therapy should be based both on tumor biology and on therapeutic response in parallel. Associated translational research and mathematical prediction tools such as nomograms also are introduced. This book provides the essence of primary breast cancer care, particularly its individualization with novel therapeutic concepts and strategies, and will greatly benefit physicians and clinical investigators in breast cancer institutions.
- Contents
- Part I. Treatment for the Patients Having Breast Cancer High-Risk -- 1 Risk-Reducing Surgery for Breast Cancer Patients with BRCA Mutations -- 2 Prophylactic Risk Reducing Surgery for Breast Cancer -- 3 Merits and Demerits of Practice for Hereditary Breast and Ovarian Cancer Syndrome (Advices and Issues) -- Part II. Axillary Treatment -- 4 Sentinel Lymph Node Biopsy and Neoadjuvant Chemotherapy in Breast Cancer Patients -- 5 Axillary Reverse Mapping (ARM) as a Means to Reduce Lymphedema During Sentinel Lymph Node or Axillary Node Dissection -- 6 Ultrasound for Axillary Staging -- 7 One Step Nucleic Acid Amplification (OSNA)Assay for Primary Breast Cancer -- 8 Management of the Clinically Node-Negative Axilla in Primary Breast Cancer -- 9 Lymphatic Mapping and Optimization of Sentinel Lymph Node Dissection -- Part III. Radiation therapy -- 10 Personalization of Radiotherapy for Breast Cancer -- 11 New Technologies in Radiation Therapy -- 12 Radiotherapy Following Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer -- Part IV. Preoperative Hormone Therapy -- 13 Novel Translational Research of Neoadjuvant Endocrine Therapy -- 14 Alterations of Biomarkers by Neoadjuvant Endocrine Therapy -- Part V. Preoperative chemotherapy -- 15 Essence of Neoadjuvant Therapy -- 16 The challenge to Overcome Triple Negative Breast Cancer Heterogeneity -- 17 Surgical Management of Breast Cancer after Preoperative Systemic Treatment -- 18 Imaging of Tumor Response by Preoperative Systemic Treatment -- Part VI. Preoperative anti-HER2 therapy -- 19 Human Epidermal Growth Factor Receptor (HER) Family Molecular Structure -- 20 Locoregional Therapy Following Neoadjuvant Therapy for HER2-Positive Breast Cancer: Opportunities and Challenges -- Part VII. Mathematical prediction/assessment model -- 21 Nomograms to predict positive resection margin and to predict 3 or more positive lymph nodes -- 22 Practical Use of Nomograms -- 23 Data Mining and Mathematical Model Development.
- Format
- e-Book
- Location
- Online
Personalized Treatment Options in Dermatology
https://libcat.nshealth.ca/en/permalink/provcat39448
Thomas Bieber, Frank Nestle, editors.
--Berlin, Heidelberg:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
This book is a quick reference guide to the new, more personalized approaches to the management of skin disorders that have emerged as a result of progress in our understanding of the genetic background and pathophysiology of skin diseases and the diversity of mechanisms underlying their clinical heterogeneity. A wide range of personalized and targeted therapies are described, including those for different skin cancers, chronic inflammatory skin diseases, and autoimmune diseases. In addition, r…
- Available Online
- View e-Book
- Other Authors
- Bieber, Thomas
- Nestle, Frank
- Responsibility
- Thomas Bieber, Frank Nestle, editors
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (v, 146 p. : 29 illus., 26 illus. in color)
- ISBN
- 9783662458402
- 9783662458396 (print ed.)
- Subjects (MeSH)
- Dermatology - methods
- Precision Medicine - methods
- Skin Diseases - therapy
- Abstract
- This book is a quick reference guide to the new, more personalized approaches to the management of skin disorders that have emerged as a result of progress in our understanding of the genetic background and pathophysiology of skin diseases and the diversity of mechanisms underlying their clinical heterogeneity. A wide range of personalized and targeted therapies are described, including those for different skin cancers, chronic inflammatory skin diseases, and autoimmune diseases. In addition, readers will find that the book documents how research results in personalized medicine can be effectively transferred to dermatological practice and looks forward to future treatments that might be developed on the basis of recent research findings. The authors are all recognized experts in the field, and the text is presented in a reader-friendly format and well illustrated.
- Contents
- 1. Concept and Scientific Background of Personalized Medicine -- 2. Melanoma: From Tumor-Specific Mutations to a New Molecular Taxonomy and Innovative Therapeutics -- 3. Targeted and Personalized Therapy for Nonmelanoma Skin Cancers -- 4. Personalized Treatment in Cutaneous T-Cell Lymphoma (CTCL) -- 5. Personalized Management of Atopic Dermatitis: Beyond Emollients and Topical Steroids -- 6. Targeted Therapies and Biomarkers for Personalized Treatment of Psoriasis -- 7. Autoinflammatory Syndromes: Relevance to Inflammatory Skin Diseases and Personalized Medicine -- 8. The Personalized Treatment for Urticaria -- 9. Acknowledging the Clinical Heterogeneity of Lupus Erythematosus -- 10. Bullous Diseases: Old Blisters with New Therapeutic Targets.
- Format
- e-Book
- Location
- Online
PET/CT in Prostate Cancer
https://libcat.nshealth.ca/en/permalink/provcat41826
Gary Cook, editor.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This pocket book explains the significant and well-documented impact that PET/CT can have on the management of prostate cancer through the provision of high-quality evidence regarding function and structure. Up-to-date information is supplied on the relevance of PET/CT to diagnosis, treatment planning, and therapy, including the emerging role of PET/CT with PSMA. Readers will also find clear explanation of the relation of the clinical and pathological background to imaging and the value of PET/…
- Available Online
- View e-Book
- Other Authors
- Cook, Gary
- Responsibility
- Gary Cook, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xvi, 60 pages) : 28 illus., 26 illus. in color
- Series Title
- CliniciansÇÖ Guides to Radionuclide Hybrid Imaging
- ISBN
- 9783319576244
- 9783319576237 (print ed.)
- Subjects (MeSH)
- Neoplasms - diagnostic imaging
- Positron Emission Tomography Computed Tomography - methods
- Precision Medicine - methods
- Abstract
- This pocket book explains the significant and well-documented impact that PET/CT can have on the management of prostate cancer through the provision of high-quality evidence regarding function and structure. Up-to-date information is supplied on the relevance of PET/CT to diagnosis, treatment planning, and therapy, including the emerging role of PET/CT with PSMA. Readers will also find clear explanation of the relation of the clinical and pathological background to imaging and the value of PET/CT compared with conventional radiological imaging. The book will be an excellent asset for referring clinicians, nuclear medicine/radiology physicians, radiographers/technologists, and nurses who routinely work in nuclear medicine and participate in multidisciplinary meetings. It is published within the Springer series Clinicians' Guides to Radionuclide Hybrid Imaging, which presents contributions from professionals worldwide who share a common purpose in promoting nuclear medicine as an important imaging specialty for the diagnosis and management of oncological and non-oncological conditions.
- Contents
- 1. Epidemiology and Clinical Features of Prostate cancer -- 2. Pathology of prostate cancer -- 3. Management of Prostate Cancer -- 4. Prostate cancer: Radiological Imaging -- 5. The Role of PET/CT in Prostate Cancer Management -- 6. Role of radiolabelled small molecules binding to PSMA in diagnosis and therapy of prostate cancer -- PET/CT in radiotherapy planning: current evidence in prostate cancer.
- Format
- e-Book
- Location
- Online
Precision Medicine in Cancer Therapy
https://libcat.nshealth.ca/en/permalink/provcat44534
Daniel D. Von Hoff, Haiyong Han, editors.
--Cham:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies. It also discusses emerging technologies that are making a significant impact on precision medicine in cancer therapy. In addition to describing specific approaches that have already entered clinical practice, the book explores new concepts and tools that are being developed. Precision medicine aims to deliver personalized healthcare tailore…
- Available Online
- View e-Book
- Other Authors
- Von Hoff, Daniel D.
- Han, Haiyong
- Responsibility
- Daniel D. Von Hoff, Haiyong Han, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (x, 283 p.)
- Series Vol.
- v. 178
- Series Title
- Cancer treatment and research
- ISBN
- 9783030163914
- 9783030163907 (Print ed.)
- 9783030163921 (Print ed.)
- 9783030163938 (Print ed.)
- ISSN
- 0927-3042
- Subjects (MeSH)
- Genetic Techniques
- Neoplasms - drug therapy
- Precision Medicine - methods
- Specialty
- Medical Oncology
- Precision Medicine
- Abstract
- This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies. It also discusses emerging technologies that are making a significant impact on precision medicine in cancer therapy. In addition to describing specific approaches that have already entered clinical practice, the book explores new concepts and tools that are being developed. Precision medicine aims to deliver personalized healthcare tailored to a patient’s genetics, lifestyle and environment, and cancer therapy is one of the areas in which it has flourished in recent years. Documenting the latest advances, this book is of interest to physicians and clinical fellows in the front line of the war on cancer, as well as to basic scientists working in the fields of cancer biology, drug development, biomarker discovery, and biomedical engineering. The contributing authors include translational physicians with first-hand experience in precision patient care.
- Contents
- Part I. Individual Types of Cancer Precision Medicine -- 1. Targeted Therapies in Non-small-Cell Lung Cancer -- 2. Update on Precision Medicine in Breast Cancer -- 3. The Role of Precision Medicine in the Diagnosis and Treatment of Patients with Rare Cancers -- Part II. Currently Available Techniques -- 4. Immunohistochemistry-Enabled Precision Medicine -- 5. Genomics-Enabled Precision Medicine for Cancer -- 6. Utilization of Proteomic Technologies for Precision Oncology Applications -- 7. Precision Medicine-Enabled Cancer Immunotherapy -- Part III. Future Precision Medicine -- 8. Use of Precision Imaging in the Evaluation of Pancreas Cancer -- 9. Single-Cell Sequencing in Precision Medicine -- 10. Human Microbiota and Personalized Cancer Treatments: Role of Commensal Microbes in Treatment Outcomes for Cancer Patients -- 11. Artificial Intelligence and Personalized Medicine.
- Format
- e-Book
- Location
- Online
Precision Medicine in Gynecology and Obstetrics
https://libcat.nshealth.ca/en/permalink/provcat41960
Ikuo Konishi, editor.
--Singapore:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This volume presents the scientific advances and current status of our understanding of precision medicine for common diseases in gynecology and obstetrics. Standard treatments based on clinical guidelines in the field have been established for decades, and those are essential to daily clinical practice. Meanwhile comprehensive genomic and genetic analyses have led to personalized medicine by precise clinical and genomic approaches. This book is organized into two major parts, gynecology and ob…
- Available Online
- View e-Book
- Other Authors
- Konishi, Ikuo
- Responsibility
- Ikuo Konishi, editor
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (viii, 250 pages) : 47 illus., 41 illus. in color
- Series Title
- Comprehensive gynecology and obstetrics
- ISBN
- 9789811024894
- 9789811024887 (print ed.)
- ISSN
- 2364-1932
- Subjects (MeSH)
- Genital Neoplasms, Female - therapy
- Precision Medicine - methods
- Pregnancy Complications - therapy
- Abstract
- This volume presents the scientific advances and current status of our understanding of precision medicine for common diseases in gynecology and obstetrics. Standard treatments based on clinical guidelines in the field have been established for decades, and those are essential to daily clinical practice. Meanwhile comprehensive genomic and genetic analyses have led to personalized medicine by precise clinical and genomic approaches. This book is organized into two major parts, gynecology and obstetrics, and the chapters in each part give a clear exposition of the current knowledge and the future perspectives for the treatment of various gynecological cancers, maternal disorders, and other diseases that affect female patients. Topics on novel treatment strategy with the application of molecular targeted drugs, immunotherapy, and prevention medicine are also covered. This collection benefits not only experienced gynecologists and obstetricians, but also young physicians who would like to begin clinical and basic research on diseases in women, researchers in basic medicine, and all medical oncologists who are involved in gynecological cancers.
- Contents
- Part 1: Introduction -- 1. Toward Precision Medicine in Gynecology and Obstetrics -- Part 2: Gynecology -- 2. Genomics in Gynecological Cancer: Future Perspective -- 3. Signal Transduction and Targeted Therapy for Gynecologic Cancer -- 4. Immune Therapy for Gynecologic Cancer: Coming True -- 5. Prevention of Cervical Cancer: Era of HPV Testing and Vaccination -- 6. Pathology, Genomics, and Treatment of Endometrial Cancer -- 7. Diversity in Pathology and Genomics in Ovarian Cancer -- 8. Hereditary Ovarian and Endometrial Cancers: Current Management -- 9. Molecular Pathology and Novel Therapy for Uterine Sarcomas -- Part 3:Obstetrics -- 10. Recurrent Pregnancy Loss: Current Evidence and Clinical Guideline -- 11. Genomic Approach for Recurrent Abortions: Prevention Feasible? -- 12. Prenatal Diagnosis of Embryo and Fetus in the Human -- 13. Pathology and Genomics in Gestational Trophoblastic Neoplasia -- 14. Genomic Analysis for Hypertension in Pregnancy -- 15. Molecular Mechanisms for Preterm Delivery -- 16. Developmental Origins for Health and Disease (DOHaD): Future Perspective.
- Format
- e-Book
- Location
- Online
