topic:"Progestins" found 3 records - Provincial Hospitals Library Catalogue

Frontiers in Gynecological Endocrinology. Volume 6, Sex Steroids' Effects on Brain, Heart and Vessels

https://libcat.nshealth.ca/en/permalink/provcat44448

Roberta Diaz Brinton, Andrea R. Genazzani, Tommaso Simoncini, John C. Stevenson, editors. --Cham: Springer , c2019.

Available Online: View e-Book

Location: Online

This book analyzes the effects of estrogens and progesterone on brain cells, the immune system, neuro inflammation, myelin formation and steroid receptor distribution, as well as their clinical impacts. It also explores the relationship between sex-steroid withdrawal and the development of brain symptoms such as hot flushes, sleep disorders, mood changes, depression and also cognitive disorders and dementia, as well as the effects of hormone menopause therapy on such symptoms and diseases. Star…

Available Online: View e-Book

Other Authors: Brinton, Roberta Diaz; Genazzani, Andrea R.; Simoncini, Tommaso; Stevenson, John C.

Other Authors: International Society of Gynecological Endocrinology

Responsibility: Roberta Diaz Brinton, Andrea R. Genazzani, Tommaso Simoncini, John C. Stevenson, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2019

Physical Description: 1 online resource (vi, 294 p.) : 64 illus., 52 illus. in color

Series Vol.: v. 6

Series Title: ISGE series; Frontiers in gynecological endocrinology series

ISBN: 9783030113551; 9783030113544 (Print ed.); 9783030113568 (Print ed.)

ISSN: 2197-8735

Subjects (MeSH): Estrogens; Hormone replacement therapy; Menopause - physiology; Progestins

Specialty: Endocrinology; Gynecology

Abstract: This book analyzes the effects of estrogens and progesterone on brain cells, the immune system, neuro inflammation, myelin formation and steroid receptor distribution, as well as their clinical impacts. It also explores the relationship between sex-steroid withdrawal and the development of brain symptoms such as hot flushes, sleep disorders, mood changes, depression and also cognitive disorders and dementia, as well as the effects of hormone menopause therapy on such symptoms and diseases. Starting with obstetrical history and cardiovascular risk in later life, the second part of the book examines the effects of estrogens and progestogens on vascular tissues, atherosclerosis and coronary heart diseases, as well as the impact of hormone replacement therapies on cardiovascular risks and mortality. This volume is a useful, clear and up-to-date tool for gynecologists, endocrinologists, neurologists and cardiologists, and serves as a valuable source of information for all physicians involved in women’s health.

Contents: 1. Neuroendocrine Changes of the Menopausal Transition -- 2. The Neurological and Immunological Transitions of the Perimenopause: Implications for Postmenopausal Neurodegenerative Disease -- 3. Estrogenic Regulation of Neuroprotective and Neuroinflammatory Mechanisms: Implications for Depression and Cognition -- 4. Estetrol and Its Effects on the Damaged Brain -- 5. Adrenal Androgens Impact on Neurosteroids -- 6. Do Menopausal Symptoms Account for the Declines in Cognitive Function During the Menopausal Transition? -- 7. Allopregnanolone as a Therapeutic to Regenerate the Degenerated Brain -- 8. Reproductive Depression and the Response to Hormone Therapy -- 9. Sex, Gender, and the Decline of Dementia -- 10. Obstetric History and Cardiovascular Disease (CVD) Risk -- 11. HRT and Cardiovascular Disease -- 12. Unique Vascular Benefits of Estetrol, a Native Fetal Estrogen with Specific Actions in Tissues (NEST) -- 13. Vascular Effects of Progestogens -- 14. Sex Differences, Progesterone, and Ischemic Stroke -- 15. Atherogenesis: Estrogen Induction of Polysialylated nCAM (PSA-nCAM) Blocks Monocyte Capture by Vascular Endothelial Cells -- 16. Cardiovascular Risk in Climacteric Women: When to Begin the Hormone Treatment? -- 17. HRT for the Primary Prevention of Coronary Heart Disease -- 18. Symptoms and Hormones: Fine-Tuning Atherosclerotic Risk? -- 19. Cardiovascular Mortality Risk and HRT -- 20. HT: Pharmacology Tailored to Women’s Health.