Cover -- Half-title -- Title -- Copyright -- Contents -- Preface -- Acknowledgments -- 1 Introduction -- Skin disease and psychology: a multitude of links -- Skin disease and body image -- Self-schema(s) and body image -- The psychological impact of skin disease -- Management -- Theoretical models and psychodermatology -- The diatheses-stress paradigm -- Stress and dermatology -- About the book -- REFERENCES -- 2 Psychoneuroimmunology -- Introduction -- History -- Afferent pathway -- Efferent pathway -- Responses -- The neuroendocrine pathway -- Changes in disease -- Cytokines in depression and anxiety -- Inflammatory skin disease -- Atopic eczema -- Psoriasis -- Cutaneous viral infections -- Conclusion -- REFERENCES -- 3 Psychiatric comorbidity in dermatological disorders -- Introduction -- Major depressive disorder -- Obsessive-compulsive disorder -- Social phobia (social anxiety disorder) -- Post-traumatic stress disorder -- BDD and other body image pathologies -- Delusional disorder and other psychotic symptoms -- Personality disorders -- Conclusion -- REFERENCES -- 4 Stigmatisation and skin conditions -- What types of stigmatisation do people encounter? -- What is the nature of these experiences? -- Why does stigmatisation occur? -- What effects does stigmatisation have? -- Why does stigmatisation matter? -- How might stigmatisation be reduced? -- Future research -- REFERENCES -- 5 Coping with chronic skin conditions: factors important in explaining individual variation in adjustment -- Introduction -- Defining skin conditions' -- What do people living with chronic skin conditions have to cope with? -- The symptoms and their treatments -- The social and psychological impact of skin conditions -- Individual variation in the psychosocial impact -- Explanatory factors in coping and adjustment -- Disease and treatment factors -- Predisposing developmental factors -- Ongoing sociocultural factors -- Cognitive factors: personality characteristics and core beliefs -- Coping -- Conclusion -- REFERENCES -- 6 Skin disease and relationships -- In sickness and in health -- Coping and adjustment -- Attachment styles -- Appearance, attraction and shame -- Difficulties in communication -- Changes in social networks -- Body image and sexual intimacy -- Relationship-focused coping -- Conclusion -- REFERENCES -- Acknowledgements -- 7 The impact of skin disease on children and their families -- The impact of skin disease on the psychological well-being of the child and family -- Theoretical models of the psychological impact of skin disease during childhood -- The impact of skin disease on the mother-child relationship -- The impact of skin conditions on self-esteem -- Accessing psychological services for children with skin conditions -- Summary -- REFERENCES -- 8 Psychological therapies for dermatological problems -- Introduction -- Psychosocial impact of skin diseases -- Psychological approaches to treatment for dermatological conditions --t
Cover -- Front cover -- Table of contents -- Contributors -- Preface to the Fourth Edition -- About the Editors -- PROLOGUE: Exploring the Phylogenetic History of Neural-immune System Interactions: An Update -- PART I: NEURAL AND ENDOCRINE EFFECTS ON IMMUNITY -- INTRODUCTION -- CHAPTER 1: Glucocorticoids and Immunity: Mechanisms of Regulation -- ABSTRACT -- I. INTRODUCTION -- II. IMMUNITY -- III. GLUCOCORTICOIDS -- IV. GLUCOCORTICOID RECEPTOR -- V. REGULATION OF GENE EXPRESSION BY GR -- VI. INHIBITORY EFFECTS OF GLUCOCORTICOIDS ON THE IMMUNE SYSTEM -- VII. PERSPECTIVES -- CHAPTER 2: Adrenergic Regulation of Immunity -- ABSTRACT -- I. EARLY EVIDENCE THAT THE NERVOUS AND IMMUNE SYSTEMS COMMUNICATE WITH EACH OTHER -- II. SYMPATHETIC INNERVATION OF LYMPHOID TISSUE AND NOREPINEPHRINE RELEASE -- III. EVIDENCE FOR ADRENERGIC RECEPTOR EXPRESSION ON IMMUNE CELLS -- IV. EVIDENCE THAT NOREPINEPHRINE REGULATES IMMUNE CELL ACTIVITY IN VIVO -- V. EVIDENCE FOR ADRENERGIC RECEPTOR REGULATION OF IMMUNE CELL ACTIVITY IN VITRO -- VI. RELEVANCE TO HEALTH AND DISEASE -- CHAPTER 3: Cholinergic Regulation of Inflammation -- I. INTRODUCTION -- II. BRAIN-IMMUNE COMMUNICATION -- III. THE CHOLINERGIC ANTI-INFLAMMATORY PATHWAY IN MEDICINE -- IV. PERSPECTIVES -- CHAPTER 4: Significance of Sensory Neuropeptides and the Immune Response -- I. INTRODUCTION -- II. THE IMMUNE SYSTEM -- III. THE NERVOUS SYSTEM -- IV. NEUROPEPTIDES -- V. THE ENTERIC NERVOUS SYSTEM -- VI. THE CHOLINERGIC ANTI-INFLAMMATORY PATHWAY -- VII. NEUROTROPHINS -- VIII. NEUROPEPTIDE COMMUNICATION: THE DIFFERENT IMMUNE CELLS -- IX. NERVES IN THE INFLAMMATORY PROCESS -- X. NEUROGENIC INFLAMMATION -- XI. CENTRAL NERVOUS SYSTEM -- XII. STRESS RESPONSE -- XIII. NERVE-IMMUNE COMMUNICATION IN THE VARIOUS TISSUES -- XIV. SUMMARY -- CHAPTER 5: Vasoactive Intestinal Peptide: An Anti-inflammatory Neuropeptide -- ABSTRACT -- I. INTRODUCTION -- II. VIP PRESENCE IN PRIMARY AND SECONDARY LYMPHOID ORGANS -- III. VIP RECEPTORS IN IMMUNE CELLS -- IV. EFFECTS OF VIP ON INNATE IMMUNE RESPONSES -- V. EFFECTS OF VIP ON T-CELL ACTIVATION, DIFFERENTIATION, AND FUNCTION -- VI. VIP IN MODELS OF AUTOIMMUNITY, INFLAMMATION, AND BONE MARROW TRANSPLANTATION -- VII. CONCLUSIONS AND PERSPECTIVES -- VIII. ABBREVIATIONS -- CHAPTER 6: Immune-derived Opioids: Production andFunction in Infl ammatory Pain -- ABSTRACT -- I. INTRODUCTION -- II. PERIPHERAL OPIOID RECEPTORS -- III. OPIOID PEPTIDES PRODUCED BY IMMUNE CELLS -- IV. MIGRATION OF OPIOID-CONTAINING IMMUNE CELLS TO INFLAMED TISSUE -- V. RELEASE OF OPIOID PEPTIDES FROM IMMUNE CELLS -- VI. ANALGESIA PRODUCED BY IMMUNE-DERIVED OPIOID PEPTIDES -- VII. CLINICAL IMPLICATIONS -- VIII. PERSPECTIVES -- CHAPTER 7: Crosstalk between Insulin-like Growth Factors and Pro-inflammatory Cytokines -- I. INTRODUCTION -- II. THE INSULIN-LIKE GROWTH FACTOR (IGF) SYSTEM -- III. IGF TYPE I RECEPTOR SIGNALING