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99mTc-Sestamibi : Clinical Applications

https://libcat.nshealth.ca/en/permalink/provcat31092
Jan Bucerius, Hojjat Ahmadzadehfar, Hans-Jürgen Biersack, editors. --Berlin, Heidelberg: Springer , c2012.
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99mTc-sestamibi is a single-photon emission computed tomography (SPECT) radiotracer that was introduced into clinical routine for myocardial perfusion imaging more than two decades ago. Although today the main application of 99mTc-sestamibi SPECT remains the imaging of myocardial perfusion, it is also an accepted and well-proven imaging technique for a variety of oncologic and non-oncologic applications, including brain, breast, and thyroid cancer and thyroid and parathyroid adenoma. Its effica…
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Other Authors
Bucerius, Jan
Ahmadzadehfar, Hojjat
Biersack, Hans-Jürgen
Responsibility
Jan Bucerius, Hojjat Ahmadzadehfar, Hans-Jürgen Biersack, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xi, 194 p. : 19 ill., 13 ill. in color)
ISBN
9783642042331
Subjects (MeSH)
Radioactive Tracers
Radionuclide Imaging - methods
Technetium Tc 99m Sestamibi - diagnostic use
Subjects (LCSH)
Radiology, Medical
Nuclear medicine
Abstract
99mTc-sestamibi is a single-photon emission computed tomography (SPECT) radiotracer that was introduced into clinical routine for myocardial perfusion imaging more than two decades ago. Although today the main application of 99mTc-sestamibi SPECT remains the imaging of myocardial perfusion, it is also an accepted and well-proven imaging technique for a variety of oncologic and non-oncologic applications, including brain, breast, and thyroid cancer and thyroid and parathyroid adenoma. Its efficacy in a range of indications ensures that 99mTc-sestamibi SPECT will remain widely used despite the rapid diffusion of 18F-FDG PET. 99mTc-Sestamibi: Clinical Applications provides a detailed and informative overview of almost all the oncologic and non-oncologic applications of 99mTc-sestamibi SPECT, including several relatively rare indications. Different disease-related protocols for 99mTc-sestamibi SPECT are presented, and for each disease a comprehensive summary of the relevant pathology and epidemiology is provided. Throughout, there is a strong emphasis on the practical aspects of use of this popular tracer, including instructions for the preparation of several commercially available tracer kits. Clinical practitioners will find this book to be an invaluable guide to the application and benefits of 99mTc-sestamibi SPECT in both the inpatient and the outpatient setting.
Contents
1 Radiochemistry and Radiopharmacy of the SPECT-Tracer Technetium-99m-Hexakis-2-methoxy-2-isobutyl isonitrile (99mTc-Sestamibi) – 2. Physics and Radiation Exposure – 3. Preparation of Tc-99m-Sestamibi – 4. Parathyroid Imaging – 5. Myocardial Perfusion Scintigraphy with 99mTc-MIBI – 6. 99mTc-Sestamibi Scintimammography – 7. Tc-99m-MIBI for Thyroid Imaging -- 8 Tc-99m Sestamibi in Miscellaneous Tumors – 9. Oncologic Applications of Sestamibi: In Vivo Imaging of Multi-Drug Resistance – Index.
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e-Book
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Online
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Autonomic Innervation of the Heart : Role of Molecular Imaging

https://libcat.nshealth.ca/en/permalink/provcat39435
Riemer H.J.A. Slart, Ren© A. Tio, Philip H. Elsinga, Markus Schwaiger, editors. --Berlin, Heidelberg: Springer , c2015.
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This book explains in detail the potential value of the hybrid modalities, SPECT-CT and PET-CT, in the imaging of cardiac innervation in a wide range of conditions and diseases, including ischemic heart disease, diabetes mellitus, heart failure, amyloidosis, heart transplantation, and ventricular arrhythmias. Imaging of the brain-heart axis in neurodegenerative disease and stress and of cardiotoxicity is also discussed. The roles of the various available tracers are fully considered, and indivi…
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Other Authors
Slart, Riemer H.J.A
Tio, Ren© A
Elsinga, Philip H
Schwaiger, Markus
Responsibility
Riemer H.J.A. Slart, Ren© A. Tio, Philip H. Elsinga, Markus Schwaiger, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xvii, 465 p. : 100 illus., 64 illus. in color)
ISBN
9783662450741
9783662450734 (print ed.)
Subjects (MeSH)
Autonomic Nervous System - diagnostic imaging
Heart - diagnostic imaging
Heart - innervation
Molecular Imaging - methods
Radionuclide Imaging - methods
Abstract
This book explains in detail the potential value of the hybrid modalities, SPECT-CT and PET-CT, in the imaging of cardiac innervation in a wide range of conditions and diseases, including ischemic heart disease, diabetes mellitus, heart failure, amyloidosis, heart transplantation, and ventricular arrhythmias. Imaging of the brain-heart axis in neurodegenerative disease and stress and of cardiotoxicity is also discussed. The roles of the various available tracers are fully considered, and individual chapters address radiopharmaceutical development under GMP, imaging physics, and kinetic modeling software. Highly relevant background information is included on the autonomic nervous system of the heart and its pathophysiology, and in addition future perspectives are discussed. Awareness of the importance of autonomic innervation of the heart for the optimal management of cardiac patients is growing, and there is an evident need for objective measurement techniques or imaging modalities. In this context, Autonomic Innervation of the Heart will be of wide interest to clinicians, researchers, and industry.
Contents
[publisher supplied] Autonomic nervous system of the heart -- Pathophysiology of the autonomic nervous system of the heart -- Tracers for Presynaptic Cardiac Innervation -- Tracers of Adrenergic Receptors -- Tracers of the Parasympathetic System -- Radiopharmaceuticals production under GMP -- Physics of PET-CT and SPECT-CT -- Kinetics & software PET -- SPECT-CT imaging of autonomic innervation in heart diseases -- PET-CT imaging of autonomic innervation in heart diseases -- Imaging ischemic heart disease -- Imaging diabetes mellitus -- Imaging heart failure -- Imaging amyloidosis -- Imaging heart transplantation -- Imaging ventricular arrhythmias -- Guided therapy & imaging -- Imaging the functional brain-heart axis: neurodegenerative diseases -- Imaging the functional brain-heart axis: mental stress & anxiety -- Imaging cardiotoxicity: the effects of chemo- and mono-clonal antibody therapy on autonomic innervation -- Imaging cardiotoxicity: the effect of radiotherapy on autonomic innervation -- Summary and Future Perspectives: PET-MRI Imaging of cardiac Innervation, fluorescence imaging of cardiac innervation.
Format
e-Book
Location
Online
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Clinical Assessment of the Autonomic Nervous System

https://libcat.nshealth.ca/en/permalink/provcat41917
Satoshi Iwase, Junichiro Hayano, Satoshi Orimo, editors. --Tokyo: Springer , 2017.
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This book describes newly developed methods of assessing the autonomic nervous system. Up-to-date information on microneurographic analysis of human cardiovascular and thermoregulatory function in humans, heart rate variability, and 131I-metaiodobenzylguanidine (MIBG) scintigraphy are provided. Microneurography, which was originally developed as a technique to analyze the afferent muscle spindle, came to be used to analyze sympathetic nerve activity in the mid-1980s. In the twenty-first century…
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Other Authors
Iwase, Satoshi
Hayano, Junichiro
Orimo, Satoshi
Responsibility
Satoshi Iwase, Junichiro Hayano, Satoshi Orimo, editors
Place of Publication
Tokyo
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (viii, 317 pages) : 103 illus., 38 illus. in color
ISBN
9784431560128
9784431560104 (print ed.)
Subjects (MeSH)
Cardiac Imaging Techniques - methods
Arrhythmias, Cardiac - diagnosis
Autonomic Nervous System - physiopathology
Heart Rate - physiology
Radionuclide Imaging - methods
Abstract
This book describes newly developed methods of assessing the autonomic nervous system. Up-to-date information on microneurographic analysis of human cardiovascular and thermoregulatory function in humans, heart rate variability, and 131I-metaiodobenzylguanidine (MIBG) scintigraphy are provided. Microneurography, which was originally developed as a technique to analyze the afferent muscle spindle, came to be used to analyze sympathetic nerve activity in the mid-1980s. In the twenty-first century, this technique has become prevalent all over the world especially in investigating the pathophysiology of human cardiovascular function. It is also now used in researching human thermoregulatory function. Heart rate variability is another valuable tool in investigating the current status of human vagal function and in predicting future cardiovascular disease. MIBG is also used to assess cardiac noradrenergic function, especially decreases associated with Parkinson's disease, Lewy body disease, and multisystem atrophy. Overviews of recent advances in these three important assessments are provided by leading experts. Clinical Assessment of the Autonomic Nervous System is a useful resource for neurologists and researchers of clinical neurophysiology.
Contents
PART I: Sympathetic Microneurography -- 1. Introduction to Sympathetic Microneurography -- 2. Muscle Sympathetic Nerve Activity in Neurological Disorders -- 3. Muscle Sympathetic Nerve Activity and Cardiovascular Diseases -- 4. Skin sympathetic nerve activity and thermoregulatory control in humans -- 5. Muscle Sympathetic Nerve Activity and Syncope -- 6. Single Fiber Analysis of Muscle Sympathetic Nerve Activity -- PART II: Heart Rate Variability (HRV) -- 7. Introduction to Heart Rate Variability -- 8. Respiratory Sinus Arrhythmia and Entraining Heartbeats with Cheyne-Stokes Respiration - Cardiopulmonary Works to be Minimal by Synchronizing Heartbeats with Breathing -- 9. Heart RateVariability and Sympathetic Nerve Activity -- 10. Heart Rate Variability and Cardiac Diseases -- 11. Heart-rate Variability and Neurological Disorders -- PART III: Cardiac MIBG Scintigraphy -- 12. An introduction to MIBG cardiac scintigraphy -- 13. Noradrenaline and 123I-meta-iodobenzylguanidine Kinetics in the Sympathetic Nervous System -- 14. Technical Considerations for MIBG Cardiac Scintigraphy -- 15. Findings of 123I-MIBG cardiac scintigraphy : ParkinsonÇÖs disease and related disorders, and others. (RBD, cardiac diseases, DM, etc) -- 16. Findings of MIBG Cardiac Scintigraphy: Dementia with Lewy Bodies and Related Dementia -- 17. Physiological Background of Reduced Cardiac 123I-metaiodobenzylguanidine Uptake -- 18. Pathological background of reduced cardiac MIBG uptake -- 19. Clinical Implication of Reduced Cardiac MIBG Uptake.
Format
e-Book
Location
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Clinical nuclear cardiology : state of the art and future directions

https://libcat.nshealth.ca/en/permalink/provcat24603
[edited by] Barry L. Zaret, George A. Beller. (4th ed.) --Philadelphia, PA: Mosby Elsevier , 2010.
Call Number
WG 141.5 .R3 C641 2010
Location
Halifax Infirmary
Call Number
WG 141.5 .R3 C641 2010
Author
Zaret, Barry L
Other Authors
Beller, George A
Responsibility
[edited by] Barry L. Zaret, George A. Beller
Edition
4th ed.
Place of Publication
Philadelphia, PA
Publisher
Mosby Elsevier
Date of Publication
2010
Physical Description
878 p.
ISBN
9780323057967
Subjects (MeSH)
Heart - diagnostic imaging
Myocardial Ischemia - diagnostic imaging
Radionuclide Imaging - instrumentation
Radionuclide Imaging - methods
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Nuclear cardiology review : a self-assessment tool

https://libcat.nshealth.ca/en/permalink/provcat25958
--Philadelphia, PA: Wolters Kluwer Health/Lippincott Williams & Wilkins , c2013.
Call Number
WG 18.2 N964 2013
Location
Halifax Infirmary
Call Number
WG 18.2 N964 2013
Other Authors
Jaber, Wael A
Cerqueira, Manuel D
Place of Publication
Philadelphia, PA
Publisher
Wolters Kluwer Health/Lippincott Williams & Wilkins
Date of Publication
c2013
Physical Description
183 p.
ISBN
9781608319152
Subjects (MeSH)
Cardiac Imaging Techniques - Examination Questions
Cardiovascular Diseases - diagnostic imaging - Examination Questions
Heart - diagnostic imaging - Examination Questions
Image Interpretation, Computer-Assisted - Examination Questions
Radionuclide Imaging - methods - Examination Questions
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Nuclear cardiology : the basics : how to set up and maintain a laboratory

https://libcat.nshealth.ca/en/permalink/provcat21548
Wackers, Frans J. Th. --Totowa, NJ: Humana Press , 2004.
Call Number
WG 141.5 .R3 W115n 2004
Location
Halifax Infirmary
Call Number
WG 141.5 .R3 W115n 2004
Author
Wackers, Frans J. Th
Other Authors
Bruni, Wendy
Zaret, Barry L
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
2004
Physical Description
298 p. + CD-ROM
Series Title
Contemporary cardiology (Totowa, N.J. : Unnumbered)
ISBN
0896039838
Subjects (MeSH)
Heart - diagnostic imaging
Cardiovascular Diseases - diagnostic imaging
Radionuclide Imaging - methods
Diagnostic Techniques, Cardiovascular
Laboratories - organization & administration
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Orthopedic Nuclear Medicine

https://libcat.nshealth.ca/en/permalink/provcat41793
Abdelhamid H. Elgazzar. (Second edition) --Cham: Springer , 2017.
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This book, now in a revised and updated second edition, offers a comprehensive overview of the state of the art in orthopedic nuclear medicine, including the impressive recent advances in the field and the diagnosis of under-recognized conditions on the basis of their imaging patterns. The opening chapters acquaint the reader briefly with anatomic, physiologic, pathologic, and technical concepts crucial to a sound understanding of orthopedic nuclear medicine and its utilization in clinical prac…
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Author
Elgazzar, Abdelhamid H
Responsibility
Abdelhamid H. Elgazzar
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xvi, 431 pages) : 278 illus., 83 illus. in color
ISBN
9783319561677
9783319561653 (print ed.)
Subjects (MeSH)
Bone Diseases - diagnostic imaging
Bone Diseases - radiotherapy
Joint Diseases - diagnostic imaging
Joint Diseases - radiotherapy
Radionuclide Imaging - methods
Radiopharmaceuticals - therapeutic use
Abstract
This book, now in a revised and updated second edition, offers a comprehensive overview of the state of the art in orthopedic nuclear medicine, including the impressive recent advances in the field and the diagnosis of under-recognized conditions on the basis of their imaging patterns. The opening chapters acquaint the reader briefly with anatomic, physiologic, pathologic, and technical concepts crucial to a sound understanding of orthopedic nuclear medicine and its utilization in clinical practice. The imaging diagnosis of skeletal infections, trauma, vascular disorders, metabolic and neoplastic bone diseases, soft tissue calcifications, and joint disorders is then explained in detail.áTwo entirely new chapters, on bone marrow imaging and hybrid imaging of bone diseases, have been added to this edition. A separate chapter is devoted to the use of radionuclides for the treatment of bone and joint disorders. The book is richly illustrated and amply documents the effectiveness of nuclear medicine in diagnosing bone disease. It will prove invaluable to all with an interest in diagnostic and therapeutic orthopedics, including orthopedists, radiologists, rheumatologists, pediatricians, podiatrists, other clinicians, and all nuclear and molecular imaging professionals.
Contents
1. Basic Sciences of Bone and Joint Diseases -- 2. Diagnosis of Inflammatory Bone Diseases -- 3. Diagnosis of Metabolic, Endocrine and Congenital Bone Disease -- 4. Diagnosis of Traumatic Disorders -- 5. Diagnosis of Circulatory Disorders -- 6. Neoplastic Bone Diseases -- 7. Diagnosis of Joint Disorders -- 8. Bone Marrow Imaging -- 9. Diagnosis of Soft Tissue Calcification -- 10. Hybrid Imaging in the Diagnosis of Bone Diseases -- 11. Therapeutic Use of Radionuclides in Boind and Joint Disease.
Format
e-Book
Location
Online
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PET and SPECT in Psychiatry

https://libcat.nshealth.ca/en/permalink/provcat46512
Rudi A.J.O. Dierckx, Andreas Otte, Erik F.J. de Vries, Aren van Waarde, editors ; Iris E. Sommer, guest editor. (Second edition) --Cham: Springer , c2021.
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This book provides a comprehensive overview of the use of PET and SPECT in the classic psychiatric disorders such as depression, bipolar disorder, anxiety disorders, and schizophrenia. In addition, it discusses the application of these functional neuroimaging techniques in a variety of other conditions, including sleep disorders, eating disorders, autism, and chronic fatigue syndrome. The new edition has been extensively revised and updated to reflect the latest advances and results in nuclear …
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Other Authors
Dierckx, Rudi A.J.O.
Otte, Andreas
de Vries, Erik F.J.
van Waarde, Aren
Sommer, Iris E.
Responsibility
Rudi A.J.O. Dierckx, Andreas Otte, Erik F.J. de Vries, Aren van Waarde, editors ; Iris E. Sommer, guest editor
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2021
Physical Description
1 online resource (xii, 1084 p.) : 71 illus., 63 illus. in color
ISBN
9783030572310
9783030572303 (Print ed.)
9783030572327 (Print ed.)
9783030572334 (Print ed.)
Subjects (MeSH)
Mental Disorders - diagnostic imaging
Neuroimaging
Neuropsychiatry
Positron-Emission Tomography - methods
Radionuclide Imaging - methods
Tomography, Emission-Computed, Single-Photon - methods
Specialty
Diagnostic Imaging
Neurology
Psychiatry
Abstract
This book provides a comprehensive overview of the use of PET and SPECT in the classic psychiatric disorders such as depression, bipolar disorder, anxiety disorders, and schizophrenia. In addition, it discusses the application of these functional neuroimaging techniques in a variety of other conditions, including sleep disorders, eating disorders, autism, and chronic fatigue syndrome. The new edition has been extensively revised and updated to reflect the latest advances and results in nuclear imaging within the field. Most chapters are written jointly by a clinical psychiatrist and a nuclear medicine expert to ensure a multidisciplinary approach. This state of the art compendium will be of value for all who have an interest in the field of neuroscience, from psychiatrists and radiologists/nuclear medicine specialists to interested general practitioners and cognitive psychologists. Companion volumes on the use of PET and SPECT in neurology and for the imaging of neurobiological systems complete a trilogy.
Contents
Part I. Basics -- 1. Neuroimaging in Psychiatric Drug Development and Radioligand Development for New Targets -- 2. Brain PET Quantification in Neuropsychiatric Research -- 3. The Role of P-Glycoprotein at the Blood–Brain Barrier in Neurological and Psychiatric Disease -- Part II. Depression and Related Disorders -- 4. Molecular Imaging of Depressive Disorders -- 5. SPECT and PET in Late-Life Depression -- 6. Neuroimaging in Seasons and Winter Depression -- 7. Bipolar Disorders -- 8. PET and SPECT in Psychiatric Complications of Parkinson’s Disease -- 9. Psychiatric Disorders in Dementia -- Part III. Anxiety Disorders -- 10. PET and SPECT Studies in Anxiety Disorders -- 11. Neurobiology of Posttraumatic Stress Disorder -- 12. Neuroimaging in PTSD-Related Psychotherapies -- 13. Neuroimaging of Obsessive-Compulsive Disorder: Insights into Serotonergic Mechanisms -- Part IV. Psychosis and Cognitive Disorders -- 14. Dopamine and Response to Antipsychotic Medication -- 15. Acetylcholine Imaging in Psychosis -- 16. Molecular Imaging in Schizophrenia Spectrum Disorders -- 17. Neuroimaging Findings in Patients with Hallucinations: Evidence from Neurodegenerative and Psychiatric Conditions -- 18. TSPO Imaging in Psychiatric Disorders -- 19. Neuroimaging in Delirium -- Part V. Impulse Control and Related Disorders -- 20. PET and SPECT in Personality Disorders -- 21. Abnormalities of Neurotransmission in Drug Addiction -- 22. Molecular Imaging Studies in Stimulant Addiction: A Cross-Species Perspective -- 23. SPECT and PET in Eating Disorders -- 24. Impulsivity Imaging -- 25. Brain SPECT in the Behaviourally Disordered Dog -- 26. Obesity: An Addiction? Imaging of Neurotransmitter Systems in Obesity -- 27. Neuroimaging Studies of Psychopathy -- 28. Mapping and Imaging the Aggressive Brain in Animals and Humans -- Part VI. Miscellaneous Subjects -- 29. Application of PET and SPECT to the Study of Autism Spectrum Disorders -- 30. PET and SPECT Imaging in ADHD -- 31. SPECT and PET Imaging of Apathy -- 32. PET/SPECT/MRI/fMRI Studies in the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome -- 33. Sleep Disorders -- 34. PET and SPECT Imaging of Non-pharmacological Interventions for Psychiatric Disorders.
Access
NEW Springer 2021
Format
e-Book
Location
Online
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PET/CT in Tuberculosis

https://libcat.nshealth.ca/en/permalink/provcat45433
Dragana Sobic Saranovic, Mariza Vorster, Sanjay Gambhir, Thomas Neil Pascual, editors. --Cham: Springer , c2020.
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This book covers both the science of PET/CT imaging in tuberculosis and the impact that this technique can have on disease management through the provision of high-quality evidence regarding function and structure. The scientific principles of PET/CT, the radiopharmaceuticals used in the context of tuberculosis (FDG and non-FDG tracers), patient preparation, and imaging protocols are fully explained. Imaging findings obtained in different settings, including pulmonary and extrapulmonary tubercu…
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Other Authors
Sobic Saranovic, Dragana
Vorster, Mariza
Gambhir, Sanjay
Pascual, Thomas Neil
Other Authors
British Nuclear Medicine Society
Responsibility
Dragana Sobic Saranovic, Mariza Vorster, Sanjay Gambhir, Thomas Neil Pascual, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xiii, 155 p.) : 77 illus., 55 illus. in color
Series Title
Clinicians' guides to radionuclide hybrid imaging. PET/CT
ISBN
9783030470098
9783030470081 (Print ed.)
9783030470104 (Print ed.)
ISSN
2367-2439
Subjects (MeSH)
Radionuclide Imaging - methods
Tuberculosis - diagnostic imaging
Specialty
Diagnostic Imaging
Pulmonary Medicine
Abstract
This book covers both the science of PET/CT imaging in tuberculosis and the impact that this technique can have on disease management through the provision of high-quality evidence regarding function and structure. The scientific principles of PET/CT, the radiopharmaceuticals used in the context of tuberculosis (FDG and non-FDG tracers), patient preparation, and imaging protocols are fully explained. Imaging findings obtained in different settings, including pulmonary and extrapulmonary tuberculosis, tuberculosis and HIV co-infection, and evaluation of response to antituberculous therapy, are described with the aid of many high-quality illustrations. Attention is drawn to mimics of tuberculosis, pitfalls, and limitations. The book will be an excellent asset for referring clinicians, nuclear medicine/radiology physicians, radiographers/technologists, and nurses who routinely work in nuclear medicine and participate in multidisciplinary meetings.
Contents
1. Tuberculosis: A General Overview -- 2. Diagnosis of Tuberculosis: Microbiological and Imaging Perspective -- 3. Radiological Imaging in Tuberculosis -- 4. Management of Tuberculosis -- 5. FDG–PET Imaging in TB: Patient Preparation and Imaging -- 6. FDG PET in Pulmonary TB: Current Evidence -- 7. FDG PET/CT in Extrapulmonary TB: Current Evidence -- 8. FDG PET in TB and HIV -- 9. Role of PET-CT in Central Nervous System Tuberculosis -- 10. FDG PET/CT in TB: Mimics, Pitfalls, and Limitations -- 11. FDG-PET in Treatment Response Assessment of Tuberculosis -- 12. Non-FDG PET Tracers for TB Imaging.
Format
e-Book
Location
Online
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9 records – page 1 of 1.