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Clinical Applications of Nuclear Medicine Targeted Therapy

https://libcat.nshealth.ca/en/permalink/provcat42889
edited by Emilio Bombardieri, Ettore Seregni, Laura Evangelista, Carlo Chiesa, Arturo Chiti. --Cham: Springer , c2018.
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This book offers a practical and modern update on radioisotope therapy. Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients (diagnosis and non-radioisotope therapy), the radiopharmaceuticals available today, and the current radioisotopic procedures. Wherever possible, informat…
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Other Authors
Bombardieri, Emilio
Seregni, Ettore
Evangelista, Laura
Chiesa, Carlo
Chiti, Arturo
Responsibility
edited by Emilio Bombardieri, Ettore Seregni, Laura Evangelista, Carlo Chiesa, Arturo Chiti
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiv, 503 p.) : 108 illus., 73 illus. in color
ISBN
9783319630670
9783319630663 (print ed.)
9783319630687 (print ed.)
Subjects (MeSH)
Nuclear Medicine - methods
Radioisotopes - therapeutic use
Radiopharmaceuticals - therapeutic use
Radiotherapy - methods
Specialty
Radiotherapy
Abstract
This book offers a practical and modern update on radioisotope therapy. Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients (diagnosis and non-radioisotope therapy), the radiopharmaceuticals available today, and the current radioisotopic procedures. Wherever possible, information on dosimetry is included at the end of each topic, together with a list of and comments on the most recent guidelines with their recommendations for radiometabolic therapy. The book is divided into six main sections: thyroid diseases, hepatic tumors (HCC and hepatic metastases), bone metastases from prostate cancer, lymphomas, and neuroendocrine tumors. The last section is dedicated to new perspectives of radioisotope treatment. Based on contributions from of a multidisciplinary team of specialists: oncologists, surgeons, endocrinologists, hematologists, urologists, radiopharmacists and nuclear medicine physicians, it provides a comprehensive analysis of the position of radioisotope treatments among the various therapeutic options. Readers interested in targeted therapy, radiometabolic therapy, radioimmunotherapy and radiometabolic imaging will find this book both informative and insightful.
Contents
THYROID DISEASES -- Diagnosis and treatment of hyperthyroidism (Endocrinologist) -- Radiopharmaceuticals for therapy of thyroid diseases ( chemistry, mechanism of uptake, biodistribution, doses) (Radiochemist) -- Radioiodine therapy of hyperthyroidism (indications , procedures and results) ( Nucl Medicine Physician) -- Dosimetry (Physicist) -- Clinical management of thyroid cancer (Oncologist) -- Radioidine therapy of thyroid cancer (ablation, loco-regional and distant metastases, indications procedures and results) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Novel approaches of radiometabolic treatment of thyroid cancer (Nucl Medicine Physician) -- Published guidelines on radioisotopic treatments of thyroid diseases (Nucl Medicine Physician and Oncologist) -- HEPATIC CANCER -- Clinical options for treatment of hepatocellular carcinoma (HCC) (Oncologist, Surge on) -- Radiopharmaceuticals for radioembolization (characteristics, mechanism of uptake, biodistribution, doses) (Radiochemist) -- HCC radioembolization with 90Y microspheres (indications and procedures) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- The clinical problem of hepatic metastases (Oncologist, Surgeon) -- Radioembolization of hepatic metastases with 90Y microspheres (indications and procedures) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Published guidelines on radioisotope treatment of hepatocellular cancer (Nucl Medicine Physician and Oncologist) -- NEUROENDOCRINE TUMORS -- Radiopharmaceuticals for treatment of neuroendocrine tumors (mechanisn of action, biodistribution, doses) (Radiochemis inPaediatric tumors of neuroendocrine origin (Oncologist) -- Treatment with 131I—MIBG (indications procedures and results) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- GEP neuroendocrine tumors (Oncologist) -- PPRT with 90Y labeled peptides (indications ,procedures and results) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Published guidelines on radioisotope treatment of Neuroendocrine tumors(Nucl Medicine Physician and Oncologist) -- LYMPHOMAS -- Selection of lymphoma patients candidates for Radioimmunotherapy (Haematologist) -- Radiopharmaceuticals for treatment of neuroendocrine tumors (mechanisn of action, biodistribution, doses) (Radiochemist) -- Treatment with anti-CD20 Antibodies ( 90Y- ibritumomab /131 I- Tositumomab) (indications and procedures and results) (Nucl Medicine Physician) -- Radioimmunotherapy at high doses of lymphomas (Nucl Medicine Physician) -- Published guidelines on radioisotope treatment of Lymphomas (Nucl Medicine Physician and Oncologist) -- PROSTATE CANCER -- Overview on bone metastases from prostate cancer (Urologist, Oncologist) -- Radiopharmaceuticals for treatment of bone metastases (mechanisn of action, biodistribution, doses) (Radiochemist) -- Targeted therapy with 223Ra dichloride of bone metastases(Nucl Medicine Physician) -- Novel approaches of treatment with 223Ra based targeted therapy (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Published guidelines on radioisotope treatment of Bone Metastases (Nucl Medicine Physician and Oncologist).
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e-Book
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Online
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Clinical Nuclear Medicine

https://libcat.nshealth.ca/en/permalink/provcat30297
edited by Hans-Jürgen Biersack, Leonard M. Freeman. --Berlin, Heidelberg: Springer-Verlag , c2007.
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Author
Biersack, Hans-Jürgen
Other Authors
Freeman, Leonard M
Responsibility
edited by Hans-Jürgen Biersack, Leonard M. Freeman
Place of Publication
Berlin, Heidelberg
Publisher
Springer-Verlag
Date of Publication
c2007
ISBN
9783540280262
Subjects (MeSH)
Nuclear Medicine
Radionuclide Imaging
Radiopharmaceuticals - therapeutic use
Radiotherapy
Subjects (LCSH)
Nuclear medicine
Radiotherapy
Format
e-Book
Location
Online
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Clinical Nuclear Medicine in Pediatrics

https://libcat.nshealth.ca/en/permalink/provcat39844
Luigi Mansi, Egesta Lopci, Vincenzo Cuccurullo, Arturo Chiti, editors. (1st ed.) --Cham: Springer , c2016.
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This book provides a comprehensive state-of-the-art review of pediatric nuclear medicine, encompassing both diagnostic and therapeutic applications. Detailed attention is paid to the role of FDG PET-CT within oncology, but a variety of other long-established or less frequently used diagnostic procedures are also covered. Each indication is critically discussed from a clinical perspective, with analysis of benefits and limitations and comparison against the information yield of alternative techn…
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Other Authors
Mansi, Luigi
Lopci, Egesta
Cuccurullo, Vincenzo
Chiti, Arturo
Responsibility
Luigi Mansi, Egesta Lopci, Vincenzo Cuccurullo, Arturo Chiti, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (viii, 380 p. : 88 illus., 51 illus. in color)
ISBN
9783319213712
9783319213705 (print ed.)
Subjects (MeSH)
Nuclear Medicine - methods
Pediatrics - methods
Radionuclide Imaging
Radiopharmaceuticals - therapeutic use
Population
Child
Abstract
This book provides a comprehensive state-of-the-art review of pediatric nuclear medicine, encompassing both diagnostic and therapeutic applications. Detailed attention is paid to the role of FDG PET-CT within oncology, but a variety of other long-established or less frequently used diagnostic procedures are also covered. Each indication is critically discussed from a clinical perspective, with analysis of benefits and limitations and comparison against the information yield of alternative techniques. The coverage of therapy based on radiopharmaceuticals includes the most relevant current strategies, including those utilizing radioiodine, MIBG, or radiolabelled peptides. In addition, issues concerning the radiation risk of nuclear medicine procedures in children are addressed. All chapters have been written by international experts and include the most up-to-date scientific and clinical information.
Contents
1. Peculiar Aspects and Problems of Diagnostic Nuclear Medicine in Paediatrics -- 2. PET/MR in Children -- 3. Current Issues in Molecular Radiotherapy in Children -- 4. Radiation Risk from Medical Exposure in Children -- 5. Pediatric Nuclear Medicine in Acute Clinical Setting -- 6. Nuclear Medicine in Pediatric Cardiology -- 7. Endocrinology: Diagnostics in Children and Adolescents -- 8. Radionuclide Studies with Bone-Seeking Radiopharmaceuticals in Pediatric Benign Bone Diseases -- 9. Nuclear Medicine in Pediatric Gastrointestinal Diseases -- 10. Nuclear Medicine in Pediatric Nephro-urology -- 11. The Problem of Cancer in Children -- 12. Lymphoma -- 13. Neuroblastoma -- 14. Pediatric Sarcomas -- 15. Cerebral Tumors -- 16. Thyroid Cancer in Childhood and Adolescence -- 17. Other Neoplasms -- 18. Diagnostic Imaging in European Eastern Countries: a Russian Experience.
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e-Book
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Online
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Locoregional Radionuclide Cancer Therapy : Clinical and Scientific Aspects

https://libcat.nshealth.ca/en/permalink/provcat46497
Franklin C.L. Wong, editor. --Cham: Springer , c2021.
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This book reviews locoregional radionuclide cancer therapies (LRCT). Proving an increasingly viable alternative to radiotherapy, radionuclide therapy includes a diversity of choices of well characterized biochemical and physiologic target molecules. The delivery and retention of radionuclides may be monitored by advanced imaging for exact tissue localization and for real-time dosimetry to enable personalized precision medicine. Radiopharmaceuticals in human cancer therapies are typically delive…
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Other Authors
Wong, Franklin C.L.
Responsibility
Franklin C.L. Wong, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2021
Physical Description
1 online resource (xii, 268 p.) : 76 illus., 56 illus. in color
ISBN
9783030562670
9783030562663 (Print ed.)
9783030562687 (Print ed.)
9783030562694 (Print ed.)
Subjects (MeSH)
Neoplasms - radiotherapy
Radiopharmaceuticals - therapeutic use
Radiotherapy Dosage
Radiotherapy - methods
Specialty
Medical Oncology
Radiotherapy
Abstract
This book reviews locoregional radionuclide cancer therapies (LRCT). Proving an increasingly viable alternative to radiotherapy, radionuclide therapy includes a diversity of choices of well characterized biochemical and physiologic target molecules. The delivery and retention of radionuclides may be monitored by advanced imaging for exact tissue localization and for real-time dosimetry to enable personalized precision medicine. Radiopharmaceuticals in human cancer therapies are typically delivered in systemic routes but can also be designed for locoregional routes to harness pharmacokinetic advantages of higher payload and lower systemic toxicities. This book explores the latest advancements and clinical considerations of the locoregional approach. Throughout the chapters, the clinical and scientific bases of cancer treatment and the locoregional use of radionculides are explored. Mathematical models of radiation dosimetry of locoregional radionculdies on tissues are studied using common models for multiple commercially available radionuclides. Rodent and canine tumor models of LRCT are compared for selected radionuclides and radiopharmaceuticals. The practical aspects of radiopharmaceuticals production, marketing, transport, as well as radiation protection are reviewed. Finally, the combination of LRCT with immunotherapy and other cancer therapies and prospective future use of LRCT are discussed. This is a guide for practicing nuclear physicians, interventional radiologists, radiation oncologists, radiation scientists, veterinarians and oncologists to expand their knowledge base and to prepare for designing locoregional radionuclide cancer therapies in animals and in humans.
Contents
1. Human Cancer: Epidemiology, Hallmarks, and Defense Strategies -- 2. Cancer Treatment Modalities Systemic and Locoregional Approaches: Challenges and Opportunities of Multidisciplinary Approaches -- 3. Cancer Radiotherapy: General Considerations and Human Radiobiology -- 4. Radionuclide Cancer Therapy: Unsealed Alpha- and Beta-Emitters - 5. Locoregional Therapy: Cancer Interventions with and Without Radionuclides -- 6. Radiation Dosimetry Considerations of Locoregional Radionuclide Cancer Therapy -- 7. Voxel-Based Targeted Radionuclide Therapy Dosimetry -- 8. Locoregional Unsealed Radionuclide Cancer Therapy: Experimental Findings -- 9. Animal Cancer Therapy Models: Ready Translation to Humans -- 10. An Overview of the Regulations of Radiopharmaceuticals -- 11. Locoregional Radionuclide Cancer Therapy (LRCT) Using Sealed and Unsealed Radionuclides.
Access
NEW Springer 2021
Format
e-Book
Location
Online
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Nuclear Medicine in Infectious Diseases

https://libcat.nshealth.ca/en/permalink/provcat45060
Alberto Signore, Andor W. J. M. Glaudemans, editors. --Cham: Springer , c2020.
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This book is designed as a reference manual that is exceptional in systematically discussing every aspect of nuclear medicine imaging of infections, with careful explanation of the most up-to-date concepts and recent guidelines on diagnostic flowcharts as shared between the EANM, ESR, ESNR, ESCMID, ESC, EACVI, ECCO, ESGAR and EBJIS. It is truly comprehensive, describing all methods, all acquisition parameters, and all interpretation criteria in all infectious diseases. The early chapters discus…
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Other Authors
Signore, Alberto
Glaudemans, Andor W. J. M.
Responsibility
Alberto Signore, Andor W. J. M. Glaudemans, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (x, 279 p.) : 67 illus., 48 illus. in color
ISBN
9783030254940
9783030254933 (Print ed.)
9783030254957 (Print ed.)
9783030254964 (Print ed.)
Subjects (MeSH)
Communicable Diseases - diagnosis
Communicable Diseases - therapy
Fluorodeoxyglucose F18 - therapeutic use
Nuclear Medicine - methods
Positron Emission Tomography Computed Tomography
Radiopharmaceuticals - therapeutic use
Specialty
Diagnostic Imaging
Infectious Disease Medicine
Abstract
This book is designed as a reference manual that is exceptional in systematically discussing every aspect of nuclear medicine imaging of infections, with careful explanation of the most up-to-date concepts and recent guidelines on diagnostic flowcharts as shared between the EANM, ESR, ESNR, ESCMID, ESC, EACVI, ECCO, ESGAR and EBJIS. It is truly comprehensive, describing all methods, all acquisition parameters, and all interpretation criteria in all infectious diseases. The early chapters discuss currently available radiopharmaceuticals and nuclear medicine imaging technologies, including the hybrid modalities SPECT/CT, PET/CT, and PET/MRI. The remainder of the book is devoted to the nuclear medicine imaging of infections at different body sites as well as fever of unknown origin, fungal infections, and tuberculosis and AIDS-associated infections. Infections represent a real emergency globally, and early diagnosis and treatment follow-up will continue to pose huge challenges. In this context, Nuclear Medicine in Infectious Diseases will be a superb asset for nuclear medicine and infectious disease specialists and other clinicians everywhere.
Contents
1. Infections: The Emergency of the New Millennium -- 2. Gamma Camera Imaging of Infectious Diseases -- 3. Radiopharmaceuticals for PET Imaging of Infection -- 4. Hybrid SPECT/CT and PET/CT Imaging in Infectious Diseases -- 5. Acquisition Protocols and Image Interpretation Criteria Nuclear Medicine Imaging of Infectious Diseases -- 6. Nuclear Medicine Imaging of Soft Tissue Infections -- 7. Nuclear Medicine Imaging of Peripheral Bone Osteomyelitis and Sternal Wound Infections - 8. Imaging of Spine Infections -- 9. Nuclear Medicine Imaging of Prosthetic Joint Infections -- 10. Nuclear Medicine Imaging of Vascular Graft Infections -- 11. Nuclear Medicine Imaging of Diabetic Foot Infections -- 12. Nuclear Medicine Imaging of Cardiovascular Implantable Electronic Device Infection and Endocarditis -- 13. Nuclear Medicine Imaging of Fever of Unknown Origin -- 14. Nuclear Medicine Imaging of Infection/Inflammation by PET/CT and PET/MR -- 15. Imaging Tuberculosis and AIDS Associated Infections -- 16. Imaging Fungal Infections and Therapy Follow-Up.
Format
e-Book
Location
Online
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Nuclear Medicine Textbook : Methodology and Clinical Applications

https://libcat.nshealth.ca/en/permalink/provcat44407
Duccio Volterrani, Paola Anna Erba, Ignasi Carrió, H. William Strauss, Giuliano Mariani, editors. --Cham: Springer , c2019.
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Building on the traditional concept of nuclear medicine, this textbook presents cutting-edge concepts of hybrid imaging and discusses the close interactions between nuclear medicine and other clinical specialties, in order to achieve the best possible outcomes for patients. Today the diagnostic applications of nuclear medicine are no longer stand-alone procedures, separate from other diagnostic imaging modalities. This is especially true for hybrid imaging guided interventional radiology or sur…
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Other Authors
Volterrani, Duccio
Erba, Paola Anna
Carrió, Ignasi
Strauss, H. William
Mariani, Giuliano
Responsibility
Duccio Volterrani, Paola Anna Erba, Ignasi Carrió, H. William Strauss, Giuliano Mariani, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (xvi, 1331 p.) : 676 illus., 401 illus. in color
ISBN
9783319955643
9783319955636 (Print ed.)
9783319955650 (Print ed.)
Subjects (MeSH)
Multimodal Imaging
Nuclear Medicine - methods
Radiography, Interventional
Radiopharmaceuticals - therapeutic use
Specialty
Radiography
Radiotherapy
Abstract
Building on the traditional concept of nuclear medicine, this textbook presents cutting-edge concepts of hybrid imaging and discusses the close interactions between nuclear medicine and other clinical specialties, in order to achieve the best possible outcomes for patients. Today the diagnostic applications of nuclear medicine are no longer stand-alone procedures, separate from other diagnostic imaging modalities. This is especially true for hybrid imaging guided interventional radiology or surgical procedures. Accordingly, today’s nuclear medicine specialists are actually specialists in multimodality imaging (in addition to their expertise in the diagnostic and therapeutic uses of radionuclides). This new role requires a new core curriculum for training nuclear medicine specialists. This textbook is designed to meet these new educational needs, and to prepare nuclear physicians and technologists for careers in this exciting specialty.
Contents
Part I. Basic Science -- 1. Fundamentals of Natural and Artificial Radioactivity and Interaction of Ionizing Radiations with Matter -- 2. Single-Photon-Emitting Radiopharmaceuticals -- 3. Positron-Emitting Radiopharmaceuticals -- 4. Radiopharmaceuticals for Therapy -- 5. Methods and Instrumentation for Measuring Radioactivity -- 6. General-Purpose Gamma Cameras, Dedicated Gamma Cameras, and Gamma-Probes for Radioguided Surgery -- 7. Image Acquisition and Processing with Gamma Cameras Including Integrated SPECT/CT and Dedicated Gamma Cameras -- 8. Principles of CT and MR imaging -- 9. PET/CT and PET/MR Tomographs: Image Acquisition and Processing -- 10. Essentials of Quantitative Imaging with PET -- 11. Principles of Radiation Biology and Dosimetry for Nuclear Medicine Procedures -- 12. Radiation Protection for Patients -- 13. Radiation Protection for Personnel and the Environment -- 14. Essentials of CT Image Interpretation -- 15. Essentials of MR Image Interpretation -- 16. Image-Guided and Radioguided Surgery -- Part II. Organ/Apparatus-Specific Applications -- 17. Radionuclide Imaging for Non-tumor Diseases of the Brain -- 18. Hybrid Imaging for Tumors of the Brain -- 19. Hybrid Imaging of the Head and Neck Region -- 20. Radionuclide Imaging of Cardiovascular Disease -- 21. Radionuclide Imaging of Benign Pulmonary Diseases -- 22. Hybrid Imaging for Tumours of the Chest -- 23. Hybrid Imaging for Breast Malignancies -- 24. Hybrid Imaging and Radionuclide Therapy of Musculoskeletal Diseases -- 25. Hybrid Imaging of Melanoma and Other Cutaneous Malignancies -- 26. Hybrid Imaging and Radionuclide Therapy in Hemato-oncology -- 27. Hybrid Imaging and Radionuclide Therapy for Thyroid Disorders -- 28. Hybrid Imaging in Non-thyroidal Endocrinological Disorders -- 29. Hybrid Imaging and Radionuclide Therapy of Neuroendocrine Tumors -- 30. Radionuclide Imaging of the Nephro-Urinary Tract -- 31. Functional Imaging for Benign Conditions of the Gastrointestinal Tract -- 32. Hybrid Imaging for Malignant Conditions of the Gastrointestinal Tract -- 33. Radionuclide Therapy for Tumors of the Liver and Biliary Tract -- 34. Hybrid Imaging for Gynecologic Malignancies -- 35. Hybrid Imaging for Male Malignancies -- 36. Nuclear Medicine in Pediatrics -- 37. Hybrid Imaging of the Peripheral Lymphatic System -- 38. Molecular Guidance for Planning External Beam Radiation Therapy -- Part III. Practice and Procedures (with Supplemental Online Files) -- 39. Radiopharmacy/Radiochemistry for Conventional Single-Photon Emitting and Therapeutic Radiopharmaceuticals -- 40. Radiopharmacy/Radiochemistry for Positron-Emitting Radiopharmaceuticals, Including Quality Assurance and Process Validation Principles -- 41. Recommendations for Conducting Clinical Trials with Radiopharmaceuticals -- 42. Standard Operating Procedures for Quality Control of Gamma Cameras -- 43. Standard Operating Procedures for Quality Control of PET/CT and PET/MR Tomographs -- 44. Standard Operating Procedures for Quality Control of Instrumentation for Radioguided Surgery -- 45. Technical Aspects of Dual-Energy X-Ray Absorptiometry and Quantitative Computed Tomography for Assessment of Bone Mineral Density and Body Composition -- 46. Current Practical Guidelines for the Most Common Nuclear Medicine Procedures -- 47. Teaching Cases in Nuclear Medicine: Non-oncological Applications -- 48. Teaching Cases in Nuclear Medicine: Oncological Applications -- 49. Radiological Anatomy with CT: What the Nuclear Physician Should Know When Reading a PET/CT Scan -- 50. Radiological Anatomy with MR: What the Nuclear Physician Should Know When Reading a PET/MR Scan -- 51. Interpreting and Reporting the Results of Radionuclide Tests -- Glossary.
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e-Book
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Online
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Nuclear medicine therapy : principles and clinical applications

https://libcat.nshealth.ca/en/permalink/provcat32378
Cumali Aktolun, Stanley J. Goldsmith, editors. --New York, NY: Springer , c2013.
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Nuclear Medicine Therapy presents the state of the art in targeted radionuclide therapy, both in clinical practice and contemporary clinical investigation and trials. With contributions from an internationally-distinguished group of physicians and scientists, the book is devoted entirely to the use of nuclear medicine techniques and technology for therapy of malignant and benign diseases. Individual chapters cover the scientific principles and clinical applications of radionuclide therapy and t…
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Other Authors
Aktolun, Cumali
Goldsmith, Stanley J
Responsibility
Cumali Aktolun, Stanley J. Goldsmith, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xx, 443 p. : 120 ill., 62 ill. in color)
ISBN
9781461440215
Subjects (MeSH)
Nuclear Medicine - methods
Radioimmunotherapy - methods
Radioisotopes - therapeutic use
Radiopharmaceuticals - therapeutic use
Subjects (LCSH)
Radiology, Medical
Nuclear medicine
Radiotherapy
Abstract
Nuclear Medicine Therapy presents the state of the art in targeted radionuclide therapy, both in clinical practice and contemporary clinical investigation and trials. With contributions from an internationally-distinguished group of physicians and scientists, the book is devoted entirely to the use of nuclear medicine techniques and technology for therapy of malignant and benign diseases. Individual chapters cover the scientific principles and clinical applications of radionuclide therapy and the state of clinical trials of agents currently under investigation in the therapy of tumors involving virtually every organ system. Due to overlapping interest in techniques, indications, and clinical use, the development of radionuclide therapy attracts considerable input from other medical specialists whose collaboration is essential, including radiation and medical oncologists, hematologists, diagnostic radiologists, hepatologists, endocrinologists, and rheumatologists. And because radionuclide therapy is a rapidly evolving field of nuclear medicine, it is the aim of this volume to appeal to all specialists involved in targeted radionuclide therapy and to contribute to the standardization of the practice globally.
Contents
Lymphoma -- Leukemia -- Myeloproliferative Neoplasms -- Neuroendocrine Tumors -- Bone Metastases and Bone Pain -- Melanoma -- Brain Tumors -- Well Differentiated ThyroidCarcinomas -- Medullary Carcinoma of Thyroid -- Breast Carcinoma -- Liver Tumors-Radiomicrosphere Therapy -- Liver Tumors-Systemic Radionuclide Therapy -- Colo-rectal Carcinoma -- Pancreatic Carcinoma -- Renal Cell Carcinoma -- Prostate Carcinoma -- Radioiodine Therapy of Benign Thyroid Diseases -- Radiosynoviorthesis -- Chemistry of Therapeutic Radiopharmaceuticals -- Pretargeting: Advancing the Delivery of Therapeutic Radionuclides -- Radiobiology and Low Dose Rate Radiation Effects -- Radiation Safety Considerations for Radionuclide Therapy -- Challenges Associated with Radionuclide Therapy.
Format
e-Book
Location
Online
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Nuclear Medicine Therapy : Side Effects and Complications

https://libcat.nshealth.ca/en/permalink/provcat44392
Luca Giovanella, editor. --Cham: Springer , c2019.
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This book considers how Nuclear Medicine treatments have been further developed in the past several years and are now widely applied in clinical practice, especially in oncological patients, in addition to radioiodine therapy for various thyroid diseases. These treatments are very effective when properly indicated, but side effects and complications specifically related to the radioactive drugs and other potential clinical problems should also be considered, since other treatments, e.g. chemoth…
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Other Authors
Giovanella, Luca
Responsibility
Luca Giovanella, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (ix, 121 p.) : 15 illus., 6 illus. in color
ISBN
9783030174941
9783030174934 (Print ed.)
9783030174958 (Print ed.)
9783030174965 (Print ed.)
Subjects (MeSH)
Neoplasms - radiotherapy
Radiopharmaceuticals - adverse effects
Radiopharmaceuticals - therapeutic use
Radiotherapy - methods
Specialty
Radiotherapy
Abstract
This book considers how Nuclear Medicine treatments have been further developed in the past several years and are now widely applied in clinical practice, especially in oncological patients, in addition to radioiodine therapy for various thyroid diseases. These treatments are very effective when properly indicated, but side effects and complications specifically related to the radioactive drugs and other potential clinical problems should also be considered, since other treatments, e.g. chemotherapy or radiotherapy, are frequently administered before, simultaneously with and/or after radionuclide therapies. Consequently, cumulative toxicities and treatment interactions must be considered, and physicians prescribing treatments should be capable of preventing (when possible) and properly diagnosing and treating such side effects and complications. Accordingly, expertise in radionuclide therapy and extensive clinical expertise are required to appropriately manage critical cases. This book provides essential information on the physiopathology and radiopharmacy of radionuclide treatments and addresses potential side effects and complications by providing a rapid consultation guide for clinicians: synopses, diagnostic flow-charts and treatment schedules for a range of nuclear medicine treatments.
Contents
1. Nuclear Medicine Theranostics: Between Atoms and Patients -- 2. Radioiodine Therapy of Benign Thyroid Diseases -- 3. Radioiodine Therapy of Thyroid Cancer -- 4. Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors -- 5. 131I-MIBG Therapy of Malignant Neuroblastoma and Pheochromocytoma -- 6. Radiometabolic Therapy of Bone Metastases -- 7. Selective Internal Radiotherapy (SIRT) of Primary Hepatic Carcinoma and Liver Metastases -- 8. Radioimmunotherapy of Lymphomas.
Format
e-Book
Location
Online
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Orthopedic Nuclear Medicine

https://libcat.nshealth.ca/en/permalink/provcat41793
Abdelhamid H. Elgazzar. (Second edition) --Cham: Springer , 2017.
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Online
This book, now in a revised and updated second edition, offers a comprehensive overview of the state of the art in orthopedic nuclear medicine, including the impressive recent advances in the field and the diagnosis of under-recognized conditions on the basis of their imaging patterns. The opening chapters acquaint the reader briefly with anatomic, physiologic, pathologic, and technical concepts crucial to a sound understanding of orthopedic nuclear medicine and its utilization in clinical prac…
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Author
Elgazzar, Abdelhamid H
Responsibility
Abdelhamid H. Elgazzar
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xvi, 431 pages) : 278 illus., 83 illus. in color
ISBN
9783319561677
9783319561653 (print ed.)
Subjects (MeSH)
Bone Diseases - diagnostic imaging
Bone Diseases - radiotherapy
Joint Diseases - diagnostic imaging
Joint Diseases - radiotherapy
Radionuclide Imaging - methods
Radiopharmaceuticals - therapeutic use
Abstract
This book, now in a revised and updated second edition, offers a comprehensive overview of the state of the art in orthopedic nuclear medicine, including the impressive recent advances in the field and the diagnosis of under-recognized conditions on the basis of their imaging patterns. The opening chapters acquaint the reader briefly with anatomic, physiologic, pathologic, and technical concepts crucial to a sound understanding of orthopedic nuclear medicine and its utilization in clinical practice. The imaging diagnosis of skeletal infections, trauma, vascular disorders, metabolic and neoplastic bone diseases, soft tissue calcifications, and joint disorders is then explained in detail.áTwo entirely new chapters, on bone marrow imaging and hybrid imaging of bone diseases, have been added to this edition. A separate chapter is devoted to the use of radionuclides for the treatment of bone and joint disorders. The book is richly illustrated and amply documents the effectiveness of nuclear medicine in diagnosing bone disease. It will prove invaluable to all with an interest in diagnostic and therapeutic orthopedics, including orthopedists, radiologists, rheumatologists, pediatricians, podiatrists, other clinicians, and all nuclear and molecular imaging professionals.
Contents
1. Basic Sciences of Bone and Joint Diseases -- 2. Diagnosis of Inflammatory Bone Diseases -- 3. Diagnosis of Metabolic, Endocrine and Congenital Bone Disease -- 4. Diagnosis of Traumatic Disorders -- 5. Diagnosis of Circulatory Disorders -- 6. Neoplastic Bone Diseases -- 7. Diagnosis of Joint Disorders -- 8. Bone Marrow Imaging -- 9. Diagnosis of Soft Tissue Calcification -- 10. Hybrid Imaging in the Diagnosis of Bone Diseases -- 11. Therapeutic Use of Radionuclides in Boind and Joint Disease.
Format
e-Book
Location
Online
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Radiopharmaceuticals in nuclear pharmacy and nuclear medicine

https://libcat.nshealth.ca/en/permalink/provcat21609
Kowalsky, Richard J. (2nd ed.) --Washington, DC: American Pharmacists Association , 2004.
Call Number
WN 440 K88r 2004
Location
Halifax Infirmary
Call Number
WN 440 K88r 2004
Author
Kowalsky, Richard J
Other Authors
Falen, Steven W
Edition
2nd ed.
Place of Publication
Washington, DC
Publisher
American Pharmacists Association
Date of Publication
2004
Physical Description
825 p.
ISBN
1582120315
Subjects (MeSH)
Radiopharmaceuticals - diagnostic use
Radiopharmaceuticals - therapeutic use
Radiochemistry - methods
Nuclear Medicine
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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