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Central Nervous System Metastases : Diagnosis and Treatment

https://libcat.nshealth.ca/en/permalink/provcat45264
Rohan Ramakrishna, Rajiv S. Magge, Ali A. Baaj, Jonathan P.S. Knisely, editors. --Cham: Springer , c2020.
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This is a multi-specialty book on the diagnosis, evaluation, and treatment of CNS metastases of the brain and spine. Written by renowned experts in their fields, the book covers essential contemporary topics in CNS metastases care. The book is divided into seven parts that begin with chapters that cover the fundamental biology of disease so that subsequent chapters on imaging, diagnosis, treatment, and palliation can be properly contextualized. This text also provides a framework for understand…
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Ramakrishna, Rohan
Magge, Rajiv S.
Baaj, Ali A.
Knisely, Jonathan P.S.
Responsibility
Rohan Ramakrishna, Rajiv S. Magge, Ali A. Baaj, Jonathan P.S. Knisely, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xxv, 734 p.) : 114 illus., 78 illus. in color
ISBN
9783030429584
9783030429577 (Print ed.)
9783030429591 (Print ed.)
9783030429607 (Print ed.)
Subjects (MeSH)
Brain Neoplasms - surgery
Central Nervous System Neoplasms - diagnosis
Central Nervous System Neoplasms - therapy
Radiosurgery - methods
Spinal Neoplasms - surgery
Specialty
Medical Oncology
Neurology
Neurosurgery
Abstract
This is a multi-specialty book on the diagnosis, evaluation, and treatment of CNS metastases of the brain and spine. Written by renowned experts in their fields, the book covers essential contemporary topics in CNS metastases care. The book is divided into seven parts that begin with chapters that cover the fundamental biology of disease so that subsequent chapters on imaging, diagnosis, treatment, and palliation can be properly contextualized. This text also provides a framework for understanding the biology of radiation therapy so that radiation treatment options of the brain and spine can be more fully understood. New medications and technologies are reviewed from the perspective of maximizing efficacy and minimizing toxicity, independently and as combinatorial therapy. Central Nervous System Metastases: Diagnosis and Treatment serves as a practical reference for health care providers and trainees. It provides the comprehensive, detailed perspective required to provide holistic care to patients with metastatic disease to the brain and spine.
Contents
Part I. Fundamentals -- Epidemiology and Socioeconomic Impact of CNS Metastases -- Basic Biology of Brain Metastasis -- Preclinical Models of Brain Metastasis -- Pathology of Brain Metastases -- Role of Precision Medicine in Patients With CNS Metastasis -- Classification of Brain Metastases -- The Role of Advanced Imaging in the Management of Brain Metastases -- Part II. Evaluation of CNS Metastasis -- Clinical Presentation of Central Nervous System Metastases -- Management of Seizures in Brain Metastases -- Cerebrovascular Complications in Patients With Cancer -- Mood Disorders in Patients With CNS Metastases -- Leptomeningeal Disease and the Role of Intrathecal Therapy -- Paraneoplastic Neurological Disorders -- Systemic Therapy of Brain Metastases: Lung Cancer -- Systemic Therapy of Brain Metastases: Breast Cancer -- Systemic Therapy for Brain Metastases: Melanoma -- Systemic Therapy for Brain Metastases in Other Primary Cancers (Genitourinary, Gastrointestinal, Gynecology, Head/Neck) -- Management of Solid Tumor CNS Metastases in Children -- Part III. Radiation Therapy of CNS Metastasis -- Basic Radiobiology and Radiation Physics Primer -- Role of Whole Brain Radiotherapy -- Stereotactic Radiosurgery Technology -- Stereotactic Radiosurgery - Indications and Outcomes in Central Nervous System and Skull Base Metastases -- Hypofractionated Stereotactic Radiosurgery (HF-SRS) in the Treatment of Brain Metastases -- Challenges and Controversies in Stereotactic Radiosurgery -- Synergy of Immunotherapy and Radiosurgery -- Salvage Irradiation for Patients With Recurrent Brain Metastases -- Applications of Stereotactic Radiosurgery for Brain Metastases -- Radiation Necrosis Following the Radiosurgical Treatment of Brain Metastases -- Neurocognitive Effects of Brain Metastases and Their Treatment -- Part IV. Surgical Treatment of Brain Metastasis -- The Role of Surgery in the Management of Brain Metastases -- Intraoperative Brachytherapy for Resected Brain Metastases -- Laser Interstitial Thermal Therapy for Brain Metastases and Radiation Necrosis -- Preventing Cranial Wound Complications in Cancer Patients -- Part V. Spinal Metastases: Foundations -- Introduction to Spinal Metastases -- Epidemiology of Spinal Metastatic Disease -- Bone Metabolism in Cancer -- Systemic Therapies for Patients With Metastatic Spinal Disease -- The Role of Advanced Imaging in Spinal Metastases -- Decision Making Algorithms for Surgical Treatment of Spine Metastatic Disease -- Part VI. Surgical Treatment of Spinal Metastases -- Biomechanics of Spinal Fixation in Metastatic Disease -- Separation Surgery for Spinal Metastases -- Vertebrectomy for Spinal Metastases -- Minimally Invasive Surgery for Spinal Metastases -- Deformity Secondary to Vertebral Body Metastases -- Postoperative Complications and Spinal Metastases -- Vertebral Augmentation Procedures for Treatment of Pathologic Vertebral Body Fractures -- Spinal Laser Interstitial Thermal Therapy for Metastatic Tumors -- Optimizing Wound Healing in Metastatic Spine Surgery -- Contemporary Radiation for Spinal Metastasis and Spinal Cord Compression -- Intraoperative Radiation for Spinal Metastatic Disease -- Part VII. Pain -- Approach to Pain in Patients with Central Nervous System Metastases -- Interventions for Refractory Pain in Cancer Patients -- Complementary and Integrative Therapies (CIM) in Patients With CNS Metastasis -- The Palliative Care of Patients With Brain Metastases.
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e-Book
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Collimator-Based Tracking with an Add-On Multileaf Collimator : Modification of a commercial collimator system for realtime applications

https://libcat.nshealth.ca/en/permalink/provcat40339
Andreas Böhler. (1st ed.) --Wiesbaden: Springer Fachmedien Wiesbaden : Imprint: Springer , c2016.
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In this thesis, a tracking system was developed by modifying an add-on collimator, the Siemens Moduleaf, for realtime applications in radiotherapy. As the add-on collimator works almost completely autonomously of the linear accelerator (LinAc), no modifications to the latter were necessary. The adaptations to the Moduleaf were mainly software-based. In order to reduce the complexity of the system, outdated electronic parts were replaced with newer components where practical. Verification was pe…
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Author
Böhler, Andreas
Responsibility
Andreas Böhler
Edition
1st ed.
Place of Publication
Wiesbaden
Publisher
Springer Fachmedien Wiesbaden : Imprint: Springer
Date of Publication
c2016
Physical Description
1 online resource (xiv, 53 p. : 18 illus., 14 illus. in color)
Series Title
BestMedDiss
ISBN
9783658106584
9783658106577 (print ed.)
Subjects (MeSH)
Radiotherapy - instrumentation
Radiosurgery - methods
Abstract
In this thesis, a tracking system was developed by modifying an add-on collimator, the Siemens Moduleaf, for realtime applications in radiotherapy. As the add-on collimator works almost completely autonomously of the linear accelerator (LinAc), no modifications to the latter were necessary. The adaptations to the Moduleaf were mainly software-based. In order to reduce the complexity of the system, outdated electronic parts were replaced with newer components where practical. Verification was performed by measuring the latency of the system as well as the impact on applied dose to a predefined target volume, moving in the leaf's travel direction. Latency measurements in software were accomplished by comparing the target and current positions of the leaves. For dose measurements, a Gafchromic EBT2 film was placed beneath the target 4D phantom, in between solid water plates, and moved alongside with it. Based on the results, a tracking-capable add-on collimator seems to be a useful tool for reducing the margins for the treatment of small, slow-moving targets. Radiotherapy is one of the most important methods used for the treatment of cancer. Irradiating a moving target is also one of the most challenging tasks to accomplish in modern radiotherapy.
Contents
1. Introduction -- 2. Literature Overview -- 3. Hypothesis & Goals -- 4. Materials & Methods -- 5. Results -- 6. Discussion -- 7. Conclusions.
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e-Book
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Online
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Gamma Knife Neurosurgery

https://libcat.nshealth.ca/en/permalink/provcat28253
by Jeremy C. Ganz. --Vienna: Springer-Verlag , c2011.
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Author
Ganz, Jeremy C
Responsibility
by Jeremy C. Ganz
Place of Publication
Vienna
Publisher
Springer-Verlag
Date of Publication
c2011
ISBN
9783709103432
Subjects (MeSH)
Neoplasms - surgery
Neurosurgical Procedures
Radiosurgery - methods
Subjects (LCSH)
Radiotherapy
Neurosurgery
Format
e-Book
Location
Online
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Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy

https://libcat.nshealth.ca/en/permalink/provcat39864
Rajni A. Sethi, Igor J. Barani, David A. Larson, Mack, editors Roach, III. --Cham: Springer , c2016.
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This handbook concisely summarizes state-of-the-art information about stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), including the history and development of these modalities, the biologic rationale for these technologies, typical practices, and reported results. Developed as a companion to Handbook of Evidence-Based Radiation Oncology, Second Edition, edited by Eric Hansen and Mack Roach, III, it is organized by disease site and presents treatment techniques and rec…
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Other Authors
Sethi, Rajni A
Barani, Igor J
Larson, David A
Roach, III, Mack
Responsibility
Rajni A. Sethi, Igor J. Barani, David A. Larson, Mack, editors Roach, III
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xix, 245 p. : 12 illus. in color)
ISBN
9783319218977
9783319218960 (print ed.)
Subjects (MeSH)
Evidence-Based Medicine
Radiosurgery - methods
Radiotherapy - methods
Abstract
This handbook concisely summarizes state-of-the-art information about stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), including the history and development of these modalities, the biologic rationale for these technologies, typical practices, and reported results. Developed as a companion to Handbook of Evidence-Based Radiation Oncology, Second Edition, edited by Eric Hansen and Mack Roach, III, it is organized by disease site and presents treatment techniques and recommended imaging; safety and quality assurance; toxicities and management; recommended follow-up; and supporting evidence. Inclusion of evidence-based guidelines is intended to help inform decisions regarding the appropriateness of SRS and SBRT and guide treatment and evaluation. Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy can be easily referenced in the clinic and is a valuable guide for oncology practitioners.
Contents
Introduction to Stereotactic Radiosurgery and Stereotactic Body Radiotherapy -- Part I. Radiobiology of Stereotactic Radiosurgery and Stereotactic Body Radiotherapy -- Radiobiology of Stereotactic Radiosurgery and Stereotactic Body Radiotherapy -- Part II. Physics of Stereotactic Radiosurgery and Stereotactic Body Radiotherapy -- Physics of Stereotactic Radiosurgery and Stereotactic Body Radiotherapy -- Part III. Clinical Applications -- Intracranial Tumors -- Spine -- Head and Neck -- Lung -- Digestive System -- Genitourinary Sites -- Gynecologic Sites -- Soft Tissue Sarcoma -- Oligometastases -- Appendix A. Dose-Volume Criteria.
Format
e-Book
Publication Type
Handbook
Location
Online
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Hypofractionated and Stereotactic Radiation Therapy : A Practical Guide

https://libcat.nshealth.ca/en/permalink/provcat42650
Orit Kaidar-Person, Ronald Chen, editors. --Cham: Springer , c2018.
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This handbook summarizes the data and techniques for hypofractionation and stereotactic radiation in a clinically-accessible way. Hypofractionated radiation therapy, which consists of larger-dose radiation treatments that are given over a shorter time period compared to conventional radiation fraction sizes, is used to treat a variety of cancers, including prostate, breast, lung, and colorectal. Conventional radiation therapy and hypofractionated radiation therapy have different effectiveness r…
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Other Authors
Kaidar-Person, Orit
Chen, Ronald
Responsibility
Orit Kaidar-Person, Ronald Chen, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xxvii, 406 p.) : 51 illus., 40 illus. in color
ISBN
9783319928029
9783319928005 (print ed.)
9783319928012 (print ed.)
Subjects (MeSH)
Radiation Dose Hypofractionation
Radiosurgery - methods
Stereotaxic Techniques
Specialty
Radiotherapy
Abstract
This handbook summarizes the data and techniques for hypofractionation and stereotactic radiation in a clinically-accessible way. Hypofractionated radiation therapy, which consists of larger-dose radiation treatments that are given over a shorter time period compared to conventional radiation fraction sizes, is used to treat a variety of cancers, including prostate, breast, lung, and colorectal. Conventional radiation therapy and hypofractionated radiation therapy have different effectiveness rates for cancer treatment and have different impacts on normal tissues in terms of causing toxicity. There is a significant and growing body of literature on the use of different dosing regimens to treat a variety of cancers and radiation oncologists need to keep up with the various dosing schedules, the effect of each regimen on cancer control in different cancers, and how the different schedules affect each organ in terms of toxicity. The book thus provides concise information ranging from commonly-used dose-fractionation schemes for hypofractionated and stereotactic body radiotherapy to simulation and treatment specifications to published safety and efficacy data. Chapters additionally examine the biological rationales for the efficacy of hypofractionated radiation; present clinical studies that demonstrate the efficacy and safety of hypofractionated radiation treatment in a variety of cancers; and describe the advances in technology that have allowed hypofractionated radiation to be safely given. This is an ideal guide for radiation oncology clinicians and trainees.
Contents
1. The History and Radiobiology of Hypofractionation -- 2. The Physics of Hypofractionation and SRS/SBRT -- Part I. Benign Central Nervous System Tumors -- 3. Arteriovenous Malformation -- 4. Trigeminal Neuralgia -- 5. Meningioma -- 6. Vestibular Schwannoma -- 7. Pituitary Adenoma -- Part II. Malignant Central Nervous System Tumors -- 8. Glioblastoma -- 9. Secondary Malignant (Metastases) -- Part III. Head and Neck Tumors -- 10. Nasopharynx -- 11. Larynx -- 12. Other Head and Neck Sites -- 13. Intraoral Cone (IOC) -- 14. Brachytherapy -- 15. Intraoperative Radiotherapy (IORT) -- 16. Re-irradiation -- Part IV. Skin -- 17. Skin (Melanoma and Nonmelanoma Skin Cancers) -- Part V. Lung Tumors -- 18. Hypofractionation for Lung Tumors (Primary Malignant, Secondary Malignant) -- Part VI. Breast Cancer -- 19. Breast Cancer -- Part VII. Gastrointestinal Cancer -- 20. Hepatobiliary Malignancies -- 21. Pancreas Cancer -- 22. Rectal Cancer -- Part VIII. Genitourinary Cancer -- 23. Prostate Cancer Hypofractionation -- 24. Kidney Cancer -- Part IX. Spine Tumors and Non-Spine Bone Metastases -- 25. Spine Tumors and Non-Spine Bone Metastases -- Part X. Gynecologic Malignancies -- 26. Uterine Cervix Cancer -- 27. Endometrial Cancer.
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e-Book
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Principles and Practice of Stereotactic Radiosurgery

https://libcat.nshealth.ca/en/permalink/provcat38921
Lawrence S. Chin, William F. Regine, editors. (Second edition) --New York, NY: Springer , c2015.
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Principles and Practice of Stereotactic Radiosurgery (SRS), Second Edition aims to serve as the definitive reference textbook for SRS practitioners. It provides a theoretical basis for the use of therapeutic SRS including imaging techniques and radiobiology. The bulk of the textbook contains chapters that are comprehensive in scope on all diseases that are treated by SRS. Lastly, it addresses administrative and technical aspects of running an SRS unit. Each chapter provides an expansive treatme…
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Chin, Lawrence S
Regine, William F
Responsibility
Lawrence S. Chin, William F. Regine, editors
Edition
Second edition
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xvii, 842 p. : 351 illus., 141 illus. in color)
ISBN
9781461483632
9781461483625 (print ed.)
Subjects (MeSH)
Central Nervous System Neoplasms - surgery
Neuronavigation
Radiosurgery - methods
Radiotherapy Dosage
Radiotherapy, Computer-Assisted
Abstract
Principles and Practice of Stereotactic Radiosurgery (SRS), Second Edition aims to serve as the definitive reference textbook for SRS practitioners. It provides a theoretical basis for the use of therapeutic SRS including imaging techniques and radiobiology. The bulk of the textbook contains chapters that are comprehensive in scope on all diseases that are treated by SRS. Lastly, it addresses administrative and technical aspects of running an SRS unit. Each chapter provides an expansive treatment of the subject. Emphasis is placed on the technical aspects of SRS so that practitioners in this field will use it as a daily reference. Each subject is presented by historical context, then by its pathophysiology. Current treatment methods and results are addressed in depth. A liberal use of tables and figures enhance the presentation. A review of all major clinical studies and representative case presentations, where possible, are provided with imaging, treatment planning, and follow-up results. Each chapter is followed by one or two mini-chapters that provide a counter-viewpoint experience to the main chapter, which is oriented to SRS. These counter-viewpoint chapters are written by a noted expert in that field and address in greater detail the indications, results, and complications of their approach to the disease discussed in the main chapter. Principles and Practice of Stereotactic Radiosurgery, Second Edition is the only reference needed for neurosurgeons, radiation oncologists, and medical physicists at all levels of training and practice who are interested in SRS.
Contents
Part I. Introduction -- History of Stereotactic Radiosurgery -- Imaging and Treatment and Follow-up in Stereotactic Radiosurgery -- Techniques of Stereotactic Neurosurgery -- Part II. Radiation Biology and Physics -- The Physics of Stereotactic Radiosurgery -- Radiobiology Principles of Stereotactic Radiosurgery -- Experimental Radiosurgery Models -- Treatment Planning -- Designing and Building a Radiosurgery Unit -- Part III. Stereotactic Radiosurgery Techniques -- Gamma Knife -- LINAC -- Charged Particle -- Cyberknife -- GammaPod -- Part IV. Treatment of Disease Types -- Metastatic Brain Tumors -- Glial Tumors -- Meningiomas -- Acoustic Tumors -- Pituitary Tumors -- Pediatric Disorders -- Pineal Region Tumors -- Skull Base Tumors -- Head and Neck Tumor -- Spinal Tumors -- Arteriovenous Malformations -- Cavernous Malformations and other Vascular Abnormalities -- Trigeminal Neuralgia -- Movement Disorder -- Psychiatric and Pain Disorders -- Epilepsy -- Ocular and Orbital -- Extracranial Radiosurgery -- Part V. Patient Care and Socio-Economic Issues -- Complication Management in Radiosurgery -- Cost Effectiveness and Quality of Life.
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e-Book
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Online
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Radioguided Surgery : Current Applications and Innovative Directions in Clinical Practice

https://libcat.nshealth.ca/en/permalink/provcat39991
Ken Herrmann, Omgo E. Nieweg, Stephen P. Povoski, editors. (1st ed.) --Cham: Springer , c2016.
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This book offers a comprehensive overview of the state of the art in the practice of radioguided surgery. The opening section is devoted to the basic physics principles for detection and imaging, radiation detection device technology, principles of surgical navigation, radionuclides and radiopharmaceuticals, and radiation safety. A series of chapters then address the clinical application of radioguided surgery for a variety of malignancies, including breast cancer, melanoma and other cutaneous …
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Other Authors
Herrmann, Ken
Nieweg, Omgo E
Povoski, Stephen P
Responsibility
Ken Herrmann, Omgo E. Nieweg, Stephen P. Povoski, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xviii, 503 p. : 142 illus., 125 illus. in color)
ISBN
9783319260518
9783319260495 (print ed.)
Subjects (MeSH)
Radiosurgery - methods
Surgery, Computer-Assisted
Abstract
This book offers a comprehensive overview of the state of the art in the practice of radioguided surgery. The opening section is devoted to the basic physics principles for detection and imaging, radiation detection device technology, principles of surgical navigation, radionuclides and radiopharmaceuticals, and radiation safety. A series of chapters then address the clinical application of radioguided surgery for a variety of malignancies, including breast cancer, melanoma and other cutaneous malignancies, gynecologic malignancies, head and neck malignancies, thyroid cancer, urologic malignancies, colon cancer, gastroesophageal cancer, lung cancer, bone tumors, parathyroid adenomas, and neuroendocrine tumors. For each application, the recommended methodological approaches are discussed and the available cumulative clinical experiences of investigators from across the globe are reviewed. A conscious effort is made to highlight recent developments and innovative multidisciplinary approaches within each clinical area. Interesting issues and novel approaches are further explored through a collection of selected case reports at the end of the book. The contributing authors are all experts in their own fields, ensuring that the book will hold wide appeal for surgeons, surgical technologists, nuclear medicine physicians, nuclear medicine technologists, and various trainees.
Contents
Part I. Introduction -- The History of Radioguided Surgery: Early Historical Milestones and the Development of Later Innovative Clinical Applications -- Part II. Detailed Methodology Part -- Physics of Radioguided Surgery: Basic Principles and Methods of Radiation Detection -- The use of intraoperative small and large field of view gamma cameras for radioguided surgery -- Surgical Navigation -- Tracers applied in radioguided surgery -- Radiation Safety and Dosimetry -- Part III. Clinical Application: Breast -- Radioguided sentinel lymph node mapping and biopsy in breast cancer -- Radioguided Surgery for Non-Palpable Breast Lesions: I-125 Radioactive Seed Localization -- Radioguided Surgery for Non-Palpable Breast Lesions: Technetium-99m Radioguided Occult Lesion Localization (ROLL) -- Part IV. Clinical Application: Skin -- Radioguided sentinel lymph node mapping and biopsy in cutaneous melanoma -- Part V. Clinical Application: Head and Neck -- Sentinel lymph node mapping and biopsy in oral cancer -- Part VI. Clinical Application: Thyroid and Parathyroid -- Radioguided sentinel lymph node mapping and biopsy in thyroid cancer -- Radioguided parathyroid surgery -- Radioguided surgery of thyroid carcinoma recurrences -- Part VII. Clinical Application: Urogenital Tract -- Radioguided sentinel lymph node biopsy and lymphatic mapping in urogenital malignancies -- Radioguided sentinel lymph node mapping and biopsy in gynaecological malignancies -- Part VIII. Clinical Application: Gastrointestinal Tract -- Radioguided sentinel lymph node mapping and biopsy in esophagogastric cancer -- Radioguided sentinel lymph node mapping and biopsy in colorectal cancer -- Radioguided surgery in gastro-entero-pancreatic neuroendocrine tumors -- Part IX. Clinical Application: Thoracic -- Radioguided sentinel lymph node mapping and biopsy in non-small-cell lung cancer (NSCLC) -- Radioguided surgery of small pulmonary nodules -- Part X. Miscellaneous -- Radioguided localization of bone lesions -- Radioguided monitoring of systemic leakage during isolated limb perfusion -- Radioimmunoguided surgery: Intraoperative radioimmunodetection for the radioguided localization and resection of tumors -- 18F-FDG-directed surgery and 18F-FDG-directed interventional procedures -- Part XI. Outlook: New techniques, image fusion, optical imaging -- Fluorescent tracers, hybrid tracers -- Magnetic advances in cancer surgery -- Ultrasound fusion (SPECT/US) -- Part XII. Examples (conventional techniques and innovations) -- Case reports.
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e-Book
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Online
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Radiotherapy in Managing Brain Metastases : A Case-Based Approach

https://libcat.nshealth.ca/en/permalink/provcat45269
Yoshiya Yamada, Eric Chang, John B. Fiveash, Jonathan Knisely, editors. --Cham: Springer , c2020.
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This book provides a radiotherapy perspective on the management of brain metastases with case-based discussion. This management has been rapidly evolving in the face of changing technology, progressing systemic therapy, and paradigm changes that all impact practice. These changes can be difficult, and this text gives a practical approach to help practitioners and trainees understand these changes and incorporate them into their practices. The work has two main sections: Clinical and Technical. …
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Other Authors
Yamada, Yoshiya
Chang, Eric
Fiveash, John B.
Knisely, Jonathan
Responsibility
Yoshiya Yamada, Eric Chang, John B. Fiveash, Jonathan Knisely, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xv, 376 p.) : 157 illus., 112 illus. in color
ISBN
9783030437404
9783030437398 (Print ed.)
9783030437411 (Print ed.)
9783030437428 (Print ed.)
Subjects (MeSH)
Brain Neoplasms - radiotherapy
Neoplasm Metastasis - radiotherapy
Radiosurgery - methods
Specialty
Medical Oncology
Radiotherapy
Abstract
This book provides a radiotherapy perspective on the management of brain metastases with case-based discussion. This management has been rapidly evolving in the face of changing technology, progressing systemic therapy, and paradigm changes that all impact practice. These changes can be difficult, and this text gives a practical approach to help practitioners and trainees understand these changes and incorporate them into their practices. The work has two main sections: Clinical and Technical. The clinical section has chapters that address all aspects of radiation therapy for brain metastases, including integrating advances in surgery and drug treatments. The technical section focuses on the “how to” aspects of treatment, including treatment planning and delivery. This is an ideal guide for practicing radiation oncologists and trainees.
Contents
1. Introduction -- Part I. Clinical Overview: Brain Metastases -- 2. Brain Metastases: Introduction -- 3. Radiobiology of Stereotactic Radiosurgery -- 4. Supportive Medical Management of Brain Metastases Patients Including Treatment Complications -- 5. Neuroimaging of Brain Metastases -- 6. The Evolution of Combination Therapies Involving Surgery and Radiosurgery -- 7. Laser Interstitial Thermal Therapy for Brain Metastasis -- 8. Integrating Systemic Therapy into the Management of Brain Metastases -- 9. Indications for Stereotactic Radiosurgery: Multiple Brain Metastases -- 10. Hypofractionated Stereotactic Radiosurgery for Intact and Resected Brain Metastases -- 11. Target Delineation for Radiosurgery (Including Postoperative Cavity Radiosurgery) in Brain Metastases -- 12. Indications for Whole-Brain Radiation Therapy -- 13. Particle Therapy for the Treatment of Brain Metastases -- 14. Special Topics in Brain Metastases Management -- 15. Salvage/Reirradiation/Retreatment -- Part II. Technical: Treatment Planning and Delivery -- 16. General Techniques for Radiosurgery -- 17. Single-Isocenter, Multiple Metastasis Treatment Planning -- 18. Dose Tolerances in Brain Metastasis Management -- 19. Evaluation of the Quality of a Radiosurgery Plan -- 20. Image Guidance for Frameless Radiosurgery Including Surface Mapping -- 21. Safety Procedures and Checklists for Radiosurgery -- 22. Quality Assurance for Small Fields -- 23. Techniques of Whole Brain Radiation Therapy Including Hippocampal Avoidance.
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e-Book
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Online
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Shaped Beam Radiosurgery : State of the Art

https://libcat.nshealth.ca/en/permalink/provcat29891
edited by Antonio A. F. De Salles, Alessandra Gorgulho, Nzhde Agazaryan, Ben Slotman, Michael Selch, Aaaron J. Burwick, Raymond Schulz. --Berlin, Heidelberg: Springer-Verlag , c2011.
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Author
De Salles, Antonio A. F
Other Authors
Gorgulho, Alessandra
Agazaryan, Nzhde
Slotman, Ben
Selch, Michael
Burwick, Aaaron J
Schulz, Raymond
Responsibility
edited by Antonio A. F. De Salles, Alessandra Gorgulho, Nzhde Agazaryan, Ben Slotman, Michael Selch, Aaaron J. Burwick, Raymond Schulz
Place of Publication
Berlin, Heidelberg
Publisher
Springer-Verlag
Date of Publication
c2011
ISBN
9783642111518
Subjects (MeSH)
Radiosurgery - methods
Subjects (LCSH)
Radiotherapy
Format
e-Book
Location
Online
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Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy : A Comprehensive Guide

https://libcat.nshealth.ca/en/permalink/provcat44471
Daniel M. Trifiletti, Samuel T. Chao, Arjun Sahgal, Jason P. Sheehan, editors. --Cham: Springer , c2019.
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This book is a comprehensive review of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT): its physics, clinical evidence, indications, and future directions. The utilization of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) is increasing internationally because of several factors. First, it offers patients a local treatment option that has demonstrated effectiveness similar to traditional surgery without the morbidity of general anest…
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Trifiletti, Daniel M.
Chao, Samuel T.
Sahgal, Arjun
Sheehan, Jason P.
Responsibility
Daniel M. Trifiletti, Samuel T. Chao, Arjun Sahgal, Jason P. Sheehan, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (xix, 435 p.) : 131 illus., 111 illus. in color
ISBN
9783030169244
9783030169237 (Print ed.)
9783030169251 (Print ed.)
9783030169268 (Print ed.)
Subjects (MeSH)
Neoplasms - radiotherapy
Neoplasms - surgery
Radiosurgery - methods
Stereotaxic Techniques
Specialty
Radiotherapy
Surgical Oncology
Abstract
This book is a comprehensive review of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT): its physics, clinical evidence, indications, and future directions. The utilization of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) is increasing internationally because of several factors. First, it offers patients a local treatment option that has demonstrated effectiveness similar to traditional surgery without the morbidity of general anesthesia and open surgical resection. Second, recent advancements in the quality of scientific evidence supporting a SRS or SBRT-containing approach in patients continues to evolve and demonstrate favorable disease-specific outcomes with little, if any, toxicity in various anatomic disease sites and for various conditions including cancer, benign tumors, and other psychiatric and neurologic conditions. Third, and most provocatively, is the notion that definitive local therapy (i.e. SRS or SBRT) in patients with cancer can boost the immune system to fight cancer in other sites throughout the body. While traditional medical knowledge would suggest that all patients with metastatic cancer are incurable, there is a mounting body of evidence that there is a subset of these patients that can be cured with definitive SRS or SBRT. This volume thus delves into each of these benefits and aspects of treatment, guiding physicians to the best treatment plan for their patients. Expert, international authors provide guidelines for SRS and SBRT use by clinicians. Chapters are divided into six main sections: Radiobiology of Radiosurgery and Stereotactic Body Radiation Therapy, Intracranial Radiosurgery Technique, Intracranial Radiosurgery by Indication, Stereotactic Body Radiation Therapy Technique, Stereotactic Body Radiation Therapy by Indication, The Future of Radiosurgery and SBRT. Overall physics are explained, as well as specific considerations for particular surgical tools (including the Leksell Gamma Knife and Accuray CyberKnife), techniques (including fractionated and charged particle radiosurgery), and anatomic sites (including brain metastases, pituitary tumors, and the prostate). Detailed images and charts enhance the chapters. This book provides physicians with a single, practical resource incorporating both of these broad categories of treatment, SRS and SBRT, and better defines the current role and the direction of radiosurgery.
Contents
Part I. Radiobiology of Radiosurgery and Stereotactic Body Radiation Therapy -- Vascular-Mediated Mechanisms and SRS/SBRT -- Radio-Immunology of Ablative Radiation -- Rationale for Fractionated SRS and Single SRS Session Approaches -- Part II. Intracranial Radiosurgery Technique -- Physics of Radiosurgery -- Leksell Gamma Knife Radiosurgery -- CyberKnife Robotic Stereotactic Radiosurgery -- Linear Accelerator-Based Radiosurgery: Technique -- Fractionated Radiosurgery -- Charged-Particle Proton Radiosurgery -- Part III. Intracranial Radiosurgery by Indication -- Stereotactic Radiosurgery for Brain Metastases -- Stereotactic Radiosurgery for Pituitary Adenoma -- Stereotactic Radiosurgery for Meningioma -- Stereotactic Radiosurgery for Intracranial Arteriovenous Malformations -- Radiosurgical Management of Trigeminal Neuralgia -- Radiosurgery for Vestibular Schwannomas -- Stereotactic Radiosurgery for Glial Tumors -- Part IV. Stereotactic Body Radiation Therapy Technique -- Physics of Stereotactic Body Radiotherapy -- Immobilization for SBRT: A Crucial Prerequisite Toward Accurate Treatment -- Motion Management in Stereotactic Body Radiation Therapy -- Charged Particle Stereotactic Body Radiation Therapy -- Part V. Stereotactic Body Radiation Therapy by Indication -- Stereotactic Body Radiation Therapy (SBRT) for Primary Lung Cancer -- Stereotactic Body Radiation Therapy (SBRT) for Lung Metastases -- Stereotactic Body Radiation Therapy (SBRT) for Spinal Tumors -- Stereotactic Body Radiation Therapy for Gastrointestinal Cancers -- SAbR for Primary Prostate Cancer -- Stereotactic Ablative Radiotherapy (SAbR) for Primary Renal Cell Carcinoma -- Head and Neck Stereotactic Body Radiation Therapy -- Pediatric Radiosurgery -- Part VI. The Future of Radiosurgery and SBRT -- Patient Selection in SBRT and SRS -- SRS and SBRT Complications and Management -- SRS and SBRT Integration with Supportive Care -- Targeted Agents and Immunotherapy -- Diagnostic Imaging Advances -- Comparative Effectiveness of SBRT.
Format
e-Book
Location
Online
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Treating Prostate Cancer and Related Genitourinary Applications

https://libcat.nshealth.ca/en/permalink/provcat31097
Lee E. Ponsky, editor-in-chief ; Donald B. Fuller, Robert M. Meier, C-M Charlie Ma, co-editors. --Berlin, Heidelberg: Springer , c2012.
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Location
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Prostate cancer is the most common cancer among North American and European men, but its treatment continues to be problematic owing to serious side-effects, including erectile dysfunction, urinary incontinence, and potential lower GI complicatons. Robotic radiosurgery offers a novel, rapid, non-invasive outpatient treatment option for prostate cancer that combines robotics, advanced image-guided motion detection, and automated real-time corrective spatial positioning with submillimeter precisi…
Available Online
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Other Authors
Ponsky, Lee E
Responsibility
Lee E. Ponsky, editor-in-chief ; Donald B. Fuller, Robert M. Meier, C-M Charlie Ma, co-editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xx, 245 p. : 55 ill., 39 ill. in color)
Series Title
Robotic radiosurgery
ISBN
9783642114953
Subjects (MeSH)
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - radiotherapy
Radiosurgery - methods
Robotics - methods
Urogenital Neoplasms - radiotherapy
Subjects (LCSH)
Radiology, Medical
Radiotherapy
Oncology
Surgery
Urology
Abstract
Prostate cancer is the most common cancer among North American and European men, but its treatment continues to be problematic owing to serious side-effects, including erectile dysfunction, urinary incontinence, and potential lower GI complicatons. Robotic radiosurgery offers a novel, rapid, non-invasive outpatient treatment option for prostate cancer that combines robotics, advanced image-guided motion detection, and automated real-time corrective spatial positioning with submillimeter precision. This book examines all aspects of the treatment of prostate cancer with robotic radiosurgery. After introductory sections on radiosurgery as a multidisciplinary practice and specific issues relating to prostate cancer, the important challenge posed by prostate motion when administering radiation therapy is examined in depth, with detailed discussion as to how image-guided robotic radiosurgery overcomes this problem by continously identifying the precise location of the prostate throughout the course of treatment. A further major section is devoted to a discussion of techniques and potential radiobiological and clinical advantages of hypofractionated radiation delivery by means of robotic radiosurgery systems. The book closes by discussing other emerging genitourinary applications of robotic radiosurgery. All of the authors are experts in their field who present a persuasive case for this fascinating technique.
Contents
Part I. Introduction to Radiosurgery as a Multidisciplinary Practice -- 1. Radiosurgery, a Treatment Principle: From Brain to Body -- 2. Radiosurgery as a Multidisciplinary Practice -- 3. Building a Stereotactic Radiosurgery Program for the Treatment of Prostate Cancer -- Part II. Historical and Current Prostate Cancer Issues -- 4. Prostate Anatomy and Prostate Cancer Screening, Diagnosis, Staging, and Prevention -- 5. Prostate Surgery and the Evolution to Minimally Invasive Therapies -- Part III. Prostate Motion -- 6. Prostate Motion: Implications and Management Strategies -- 7. The Evolution of Conventionally Fractionated External-Beam Radiotherapy: Contemporary Techniques (3D-CRT/IMRT/IGRT) -- Part IV. Hypofractionated Radiation Delivery -- 8. Radiobiology of Prostate Cancer -- 9. Hypofractionated Radiation Therapy in Prostate Cancer: Rationale, History, and Outcomes -- 10. High-Dose-Rate Brachytherapy for the Treatment of Low-, Intermediate-, and High-Risk Prostate Cancer -- 11. Stereotactic Treatment for Prostate Cancer: An Overview -- 12. Stereotactic Body Radiotherapy for Prostate Cancer: Updated Results from a Prospective Trial -- 13. Prostate Radiosurgery with Homogeneous Dose Distribution: A Summary of Outcomes So Far -- 14. Virtual HDR® CyberKnife Treatment for Localized Prostatic Carcinoma: Principles and Clinical Update -- 15. Patient Selection for Robotic Radiosurgery for Clinically Localized Prostate Cancer: Come One, Come All -- Part V. Emerging Applications -- 16. Radiosurgery for Renal Tumors -- 17. Adaptive Partial-Boost Stereotactic Radiation Therapy for Muscle-Invasive Carcinoma of the Urinary Bladder -- 18. Stereotactic Body Radiotherapy for Gynecologic Malignancies -- 19. Advances in Prostate Imaging: Implications for Prostate Cancer Diagnosis and Treatment -- Index.
Format
e-Book
Location
Online
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Treating Tumors that Move with Respiration

https://libcat.nshealth.ca/en/permalink/provcat28312
edited by Harold C. Urschel, John J. Kresl, James D. Luketich, Lech Papiez, Robert D. Timmerman, Raymond A. Schulz. --Berlin, Heidelberg: Springer-Verlag , c2007.
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Location
Online
Available Online
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Author
Urschel, Harold C
Other Authors
Kresl, John J
Luketich, James D
Papiez, Lech
Timmerman, Robert D
Schulz, Raymond A
Responsibility
edited by Harold C. Urschel, John J. Kresl, James D. Luketich, Lech Papiez, Robert D. Timmerman, Raymond A. Schulz
Place of Publication
Berlin, Heidelberg
Publisher
Springer-Verlag
Date of Publication
c2007
Series Title
Robotic radiosurgery
ISBN
9783540698869
Subjects (MeSH)
Abdominal Neoplasms - radiotherapy
Lung Neoplasms - radiotherapy
Radiosurgery - methods
Radiotherapy, Computer-Assisted - methods
Respiratory Mechanics
Subjects (LCSH)
Radiotherapy
Oncology
Format
e-Book
Location
Online
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