This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (AR…
Edited by Sudhir Diwan, a former Director of Pain Medicine fellowship program at Ivy League Weill Cornell Medical College, and Timothy R. Deer, an internationally renowned expert in neuromodulation and minimally invasive spinal procedures, this atlas covers advanced procedures that normal residency and fellowship programs may not cover. It consolidates information pain fellows usually amass by traveling throughout the country to various specialized weekend courses. Advanced Procedures for Inter…
This book describes in detail a unique and very precise operative technique that uses autologous cartilage/bone grafts for the reconstruction of load-bearing joint surfaces and for dowelling of non-unions. The technique, employing diamond instruments and a wet grinding process, has been developed and refined over the past 30 years at the Center for Orthopaedic Sciences (ZOW), first in Bern and later in Munich. A step-by-step description of the method is provided for each indication, with the ai…
This book is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of cardiovascular disease. It provides a much-needed review of the rapid development and evolution of bio-fabrication techniques to engineer cardiovascular tissues as well as their use in clinical settings. The book incorporates recent advances in the biology, biomaterial design, and manufacturing of bioengineered cardiovascular tissue with their clinical applications to bridge the basic s…
This book presents comprehensive reviews for both translational research and clinical trials on cell therapy for stroke. Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating…
This multidisciplinary book provides up-to-date information on clinical approaches that combine stem or progenitor cells, biomaterials and scaffolds, growth factors, and other bioactive agents in order to offer improved treatment of urologic disorders including lower urinary tract dysfunction, urinary incontinence, neurogenic bladder, and erectile dysfunction. In providing clinicians and researchers with a broad perspective on the development of regenerative medicine technologies, it will assis…
This book reviews the current basic and clinical research into the mechanisms of cartilage injury and its management. It illustrates the considerable progress made in the search for solutions to cartilage related problems. Developing Insights in Cartilage Repair describes fundamental research and the use of biomaterials, bioreactors, and imaging as part of existing cartilage repair strategies, while revealing the on-going trends for emerging techniques. The aim of the Editors and their team of …
This book is unique in focusing expressly on regenerative medicine in the aesthetic field. With the aid of more than 400 color pictures, it provides step-by-step descriptions of procedures that can be performed easily in the private practice. The number of people pursuing anti-aging and cosmetic procedures in order to achieve a youthful, healthy, or simply improved aspect is continually increasing. At the same time the available techniques and materials have undergone rapid innovation in terms …
This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury. Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be cultured indefinitely ex vivo, and can differentiate into three germ l…
Regenerative medicine (RM) is a rapidly expanding topic within orthopedic and spine surgery, sports medicine and rehabilitation medicine. In the last ten years, regenerative medicine has emerged from the fringes as a complement and challenge to evidence-based medicine. Both clinicians and patients alike are eager to be able to offer and receive treatments that don't just surgically replace or clean old joints or inject away inflammation or work as a stop-gap measure. Regenerative medicine encom…
The research described in this book represents important steps toward understanding the development of inner ear medicine and new perspectives in regenerative medicine, including efficacy in cochlear implants and various other treatments. The book depicts the mechanisms that underlie inner ear diseases, their experimental models, and proposals for new strategies to treat their symptoms. As well, the exciting future prospects for dealing with the very common problem of inner ear diseases are exp…
This book describes an exciting new movement using regenerative medicine to treat patients with otolaryngological diseases. The emerging field of regenerative medicine uses tissue engineering, which combines medicine and engineering not only to treat the diseases themselves but also to enable recovery of the function of affected areas. As otolaryngology covers wide regions, including many diseases of the head and neck, the book is divided into sections, each corresponding to a different anatomi…
This book presents the state-of-art in regenerative procedures currently applied by aesthetic physicians, plastic surgeons and dermatologists. It is divided into two parts, the first of which provides a detailed introduction to aesthetic medicine and the aging process. The second part, in turn, addresses the current status of techniques and technologies with regard to autologous grafts, covering fat transfer, blood grafts, skin grafts and stem cells. The book examines the surgical applications …