Acceptable risk in biomedical research : European perspectives
https://libcat.nshealth.ca/en/permalink/provcat40982
Sigmund Simonsen.
--Dordrecht:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Simonsen, Sigmund, 1972-
- Responsibility
- Sigmund Simonsen
- Place of Publication
- Dordrecht
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xv, 293 p.)
- Series Vol.
- v. 50
- ISBN
- 9789400726789
- 9789400726772 (print ed.)
- Subjects (MeSH)
- Ethics, Research
- Human Experimentation - ethics
- Human Experimentation - legislation & jurisprudence
- Risk Assessment - legislation & jurisprudence
- Other Subjects
- Europe
- Contents
- Part. I Initial Issues -- 1. Introduction -- 2. Method and Material -- 3. Initial Conceptual Clarifications -- 4. Origins of the Requirement of Proportionality -- 5. The Purpose of the Requirement of Proportionality -- Part II. Which Risks, Burdens, and Potential Benefits Are Relevant, and How Should They Be Estimated? -- 6. Introduction -- 7. Which Risks, Burdens and Potential Benefits Are Relevant? -- 8. How to Estimate Risks, Burdens, and Potential Benefits -- Part III. The Assessment of Proportionality -- 9. The Requirement of Proportionality – Initial Clarifications -- 10. Therapeutic Research -- 11. Nontherapeutic Research -- 12. Nontherapeutic Research on “Vulnerable” Participants -- 13. Non-interference with Necessary Clinical Interventions and The No Harm Rule -- 14. Especially on Randomised Clinical Trials, Including Placebo Controlled Clinical Trials -- 15. Acceptable Risks and Burdens to Others than the Participant -- 16. Later Developments During the Course of the Research -- 17. Legal Effects of the Requirement of Proportionality -- Part IV. Summary and Conclusions -- 18. Summary of Results -- 19. Recommendations -- 20. Perspectives -- Appendix A: Legal Instruments -- Appendix B: Case-Law -- Appendix C: Case Examples.
- Format
- e-Book
- Location
- Online
The American Psychiatric Publishing textbook of suicide assessment and management
https://libcat.nshealth.ca/en/permalink/provcat30558
Simon, Robert I.
(2nd ed.)
--Washington, DC:
American Psychiatric Pub
, c2012.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Simon, Robert I.
- Other Authors
- Hales, Robert E
- Edition
- 2nd ed.
- Place of Publication
- Washington, DC
- Publisher
- American Psychiatric Pub
- Date of Publication
- c2012
- Physical Description
- 744 p.
- ISBN
- 9781585624140
- Subjects (MeSH)
- Suicide - psychology
- Mental Disorders - complications
- Risk Assessment - methods
- Suicide - prevention & control
- Format
- e-Book
- Location
- Online
Anesthesia in High-Risk Patients
https://libcat.nshealth.ca/en/permalink/provcat43245
Jean-Luc Fellahi, Marc Leone, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book describes the approach to anesthetic and perioperative management in different categories of high-risk patient scheduled to undergo elective noncardiac surgery. Individual sections focus on patients with conditions entailing cardiac and hemodynamic risks, respiratory risks, renal and metabolic risks, neurological risks, and other forms of risk. For each condition, up-to-date guidance is provided on risk evaluation, risk stratification, and intraoperative and postoperative anesthetic m…
- Available Online
- View e-Book
- Other Authors
- Fellahi, Jean-Luc
- Leone, Marc
- Responsibility
- Jean-Luc Fellahi, Marc Leone, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (viii, 351 p.) : 36 illus., 21 illus. in color
- ISBN
- 9783319608044
- 9783319608037 (print ed.)
- 9783319608051 (print ed.)
- 9783319869377 (print ed.)
- Subjects (MeSH)
- Anesthesia - adverse effects
- Anesthesia - methods
- Anesthetics - adverse effects
- Intraoperative Complications - prevention & control
- Perioperative Care - methods
- Risk Assessment
- Specialty
- Anesthesiology
- Critical Care
- Abstract
- This book describes the approach to anesthetic and perioperative management in different categories of high-risk patient scheduled to undergo elective noncardiac surgery. Individual sections focus on patients with conditions entailing cardiac and hemodynamic risks, respiratory risks, renal and metabolic risks, neurological risks, and other forms of risk. For each condition, up-to-date guidance is provided on risk evaluation, risk stratification, and intraoperative and postoperative anesthetic management. This is the first time that such different clinical situations have been gathered together in a single textbook of anesthesiology. All of the authors are international experts with extensive clinical experience. The aim is to provide trainee anesthesiologists with clear guidance that will prove invaluable when managing a wide range of patients with serious illnesses or conditions that pose a significant anesthetic risk. The book will also serve as a valuable reference for more experienced anesthesiologists and intensivists.
- Contents
- Part 1. Cardiac and hemodynamic risks -- The patient with acute coronary syndrome -- The patient with advanced chronic heart failure -- The patient with severe pulmonary arterial hypertension -- The patient with severe aortic stenosis -- The patient with congenital cardiac disease -- The patient with an automatic implanted device -- The patient with intra-abdominal hyperpression -- Part 2. Respiratory risks -- The patient with SOAS -- The patient with end-stage pulmonary disease -- Part 3. Renal and metabolic risks -- The patient with end-stage renal disease -- The patient with end-stage liver disease -- The severe obese patient -- Patients with rare metabolic diseases -- Part 4. Neurological risks -- Patients with cerebral diseases -- Patients with chronic neuromuscular diseases -- Part 5. Other risks -- The patient with severe sepsis -- The patient with hemorrhagic risk -- The transplanted patient -- Aged patients with a frailty syndrome -- The allergic patient -- The addicted patient -- The Jehovah Witness patient -- The pregnant women.
- Format
- e-Book
- Location
- Online
Assessment of Population Health Risks of Policies
https://libcat.nshealth.ca/en/permalink/provcat39605
Gabriel Guli¿, Odile Mekel, Bal©zs ©üd©m, Liliana Cori, editors.
--New York, NY:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Public health continues to evolve as professionals work not only to prevent disease and promote well-being but also to reduce health disparities and protect the environment. To a greater extent, policy is intimately linked to this process, a reality that is gaining traction in the public health sector. With this understanding in mind, Assessment of Population Health Risks of Policies introduces an international set of guidelines, Risk Assessment from Policies to Impact Dimension (RAPID). In kee…
- Available Online
- View e-Book
- Other Authors
- Guli¿, Gabriel
- Mekel, Odile
- ©üd©m, Bal©zs
- Cori, Liliana
- Responsibility
- Gabriel Guli¿, Odile Mekel, Bal©zs ©üd©m, Liliana Cori, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xiv, 269 p. : 9 illus.)
- ISBN
- 9781461485971
- 9781461485964 (print ed.)
- Subjects (MeSH)
- Health Policy
- Public Health
- Risk Assessment
- Risk Factors
- Abstract
- Public health continues to evolve as professionals work not only to prevent disease and promote well-being but also to reduce health disparities and protect the environment. To a greater extent, policy is intimately linked to this process, a reality that is gaining traction in the public health sector. With this understanding in mind, Assessment of Population Health Risks of Policies introduces an international set of guidelines, Risk Assessment from Policies to Impact Dimension (RAPID). In keeping with widely recognized models of public health operations, this innovative methodology factors in social, environmental, and economic health determinants to predict adverse outcomes to populations arising from large-scale policy decisions. Case studies from across the European Union illustrate both the intricacies of risk quantification and other components of assessment and possible relationships between policy and health outcomes. And contributors suggest how international health standards may be implemented despite significant cultural and political differences among nations.
- Contents
- Public health, policy analysis, risk assessment and impact assessment -- Risk assessment, Impact assessment and evaluation -- Top-Down Policy Risk Assessment -- Bottom-up policy risk assessment -- Quantification of health risks -- Application of RAPID Guidance on an International Policy -- Use of policy risk assessment results in political decision making.
- Format
- e-Book
- Location
- Online
Benefit-Risk Assessment of Medicines : The Development and Application of a Universal Framework for Decision-Making and Effective Communication
https://libcat.nshealth.ca/en/permalink/provcat39228
James Leong, Sam Salek, Stuart Walker.
--Cham:
Springer International Publishing : Imprint: Adis
, c2015.
- Available Online
- View e-Book
- Location
- Online
This book proposes and investigates a universal framework, and accompanying documentation system, to facilitate and catalogue benefit-risk decisions; a valuable addition to the benefit-risk toolbox. Over the past decade, pharmaceutical companies and regulatory agencies have been reviewing the benefit-risk assessment of medicines with a view to developing a structured, systematic, standardized approach. Examining the evaluation of such an approach by several mature regulatory authorities ensures…
- Available Online
- View e-Book
- Author
- Leong, James
- Other Authors
- Salek, Sam
- Walker, Stuart
- Responsibility
- James Leong, Sam Salek, Stuart Walker
- Place of Publication
- Cham
- Publisher
- Springer International Publishing : Imprint: Adis
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xiii, 317 p. : 163 illus., 138 illus. in color)
- ISBN
- 9783319158051
- 9783319158044 (print ed.)
- Subjects (MeSH)
- Decision Support Techniques
- Drug Approval
- Risk Assessment - methods
- Abstract
- This book proposes and investigates a universal framework, and accompanying documentation system, to facilitate and catalogue benefit-risk decisions; a valuable addition to the benefit-risk toolbox. Over the past decade, pharmaceutical companies and regulatory agencies have been reviewing the benefit-risk assessment of medicines with a view to developing a structured, systematic, standardized approach. Examining the evaluation of such an approach by several mature regulatory authorities ensures that the reader gains a unique insight into the ongoing debate in this area. The field of benefit-risk assessment continues to evolve at a rapid pace due to political and societal pressure, as is reflected in the recent FDA PUDFA agreement as well as in the EMA 2015 Roadmap. Rather than provide a comprehensive snap-shot of this constantly changing environment, this book evaluates selected current approaches to benefit-risk assessment. The strengths and weaknesses of publicly available documents in communicating benefit-risk decisions to stakeholders are reviewed, and these evaluations are used to inform development of a prospective framework that could be used to harmonise procedures globally.
- Contents
- Overview -- Approaches to utilising decision-making framework -- Benefit-risk assessment of medicines by pharmaceutical companies and regulatory authorities -- Development of a universal benefit-risk framework and template -- Implementation of the benefit-risk assessment template by mature agencies -- Implementation of the benefit- risk summary template by a maturing agency: a case study -- Communicating benefit-risk decisions by US FDA, EMA, TGA and Health Canada -- Conclusions and future directions.
- Format
- e-Book
- Location
- Online
Breast MRI Teaching Atlas
https://libcat.nshealth.ca/en/permalink/provcat41226
Richard Ha, Christopher E. Comstock, Elizabeth A. Morris, editors.
--New York, NY:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This atlas serves as a basic introduction to breast MRI. Organized by case, it emphasizes pertinent breast MRI findings and common indications for breast MRI. Topics include breast MRI basics, benign findings, breast malignancy, high-risk conditions, interesting cases, and breast implants. Brief teaching points accompany each case and highlight the importance of the findings. Breast MRI Teaching Atlas is an ideal resource for diagnostic radiologists, residents, fellows, and clinicians involved …
- Available Online
- View e-Book
- Other Authors
- Ha, Richard
- Comstock, Christopher E
- Morris, Elizabeth A
- Responsibility
- Richard Ha, Christopher E. Comstock, Elizabeth A. Morris, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xi, 310 pages) : 335 illus., 116 illus. in color
- ISBN
- 9781493964093
- 9781493964079 (print ed.)
- Subjects (MeSH)
- Breast Neoplasms - diagnostic imaging
- Breast - diagnostic imaging
- Magnetic Resonance Imaging
- Risk Assessment
- Abstract
- This atlas serves as a basic introduction to breast MRI. Organized by case, it emphasizes pertinent breast MRI findings and common indications for breast MRI. Topics include breast MRI basics, benign findings, breast malignancy, high-risk conditions, interesting cases, and breast implants. Brief teaching points accompany each case and highlight the importance of the findings. Breast MRI Teaching Atlas is an ideal resource for diagnostic radiologists, residents, fellows, and clinicians involved in the care of breast cancer patients, including surgeons, oncologists, and obstetricians/gynecologists.
- Contents
- 1. Breast MRI -- 2. Benign -- 3. Breast Malignancy -- 4. High Risk -- 5. Interesting Cases -- 6. Breast Implants.
- Format
- e-Book
- Publication Type
- Atlas
- Case Reports
- Location
- Online
Common Surgical Diseases : An Algorithmic Approach to Problem Solving
https://libcat.nshealth.ca/en/permalink/provcat38959
Theodore J. Saclarides, Jonathan A. Myers, Keith W. Millikan, editors.
(3rd ed.)
--New York, NY:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
Written by leaders in the field, the third edition of Common Surgical Diseases: An Algorithmic Approach to Problem Solving, provides surgical residents and medical students with a current, concise and algorithmic approach to frequently encountered clinical challenges. Each chapter details every common surgical disease in the form of a succinct text coupled with step-by-step algorithm. It also walks the reader through the evaluation, diagnosis, treatment and follow-up of the most common surgical…
- Available Online
- View e-Book
- Other Authors
- Saclarides, Theodore J
- Myers, Jonathan A
- Millikan, Keith W
- Responsibility
- Theodore J. Saclarides, Jonathan A. Myers, Keith W. Millikan, editors
- Edition
- 3rd ed.
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xxi, 372 p. : 95 illus., 4 illus. in color)
- ISBN
- 9781493915651
- 9781493915644 (print ed.)
- Subjects (MeSH)
- Postoperative Complications
- Risk Assessment
- Surgical Procedures, Operative
- Abstract
- Written by leaders in the field, the third edition of Common Surgical Diseases: An Algorithmic Approach to Problem Solving, provides surgical residents and medical students with a current, concise and algorithmic approach to frequently encountered clinical challenges. Each chapter details every common surgical disease in the form of a succinct text coupled with step-by-step algorithm. It also walks the reader through the evaluation, diagnosis, treatment and follow-up of the most common surgical problems. Thoroughly updated and revised, the third edition focuses on problems most frequently encountered by general surgeons and their residents and students. More factual information is included in the form of charts and tables for quick and easy reference. The section on critical care is updated and expanded. The section on pre-operative considerations has new chapters on how to best manage patient's medications before surgery (anticoagulants, anti-platelet drugs) and prophylaxis of deep venous thrombosis. Other new chapters include access for hemodialysis, adrenal incidentaloma, esophageal cancer, pancreatic cancer, management of abdominal wall defects, hyperglycemia, necrotizing soft tissue infections and SIRS/sepsis. Especially pertinent in todays' medical environment is an understanding of the genetic component of certain cancers and chapters are devoted to screening and treating patients with genetic predispositions to colorectal and breast cancer.
- Contents
- Part I. General Preoperative Considerations -- Cardiac Clearance for Non-Cardiac Surgery -- Preoperative Evaluation of Bleeding -- Managing Patient's Medications (Diabetes, Beta Blockers, NSAIDS, Anticoagulants) -- The Carotid Bruit -- DVT Prophylaxis -- Part II. Trauma -- Initial Trauma Assessment and Resuscitation -- Head Trauma -- Management of the Difficult Airway -- Penetrating Neck Trauma -- Penetrating Chest Trauma -- Penetrating Abdominal Trauma -- Blunt Abdominal Trauma -- Pelvic Fractures -- Traumatic Hematuria -- Extremity Fractures -- Burns -- Part III. Vascular Problems -- Chronic Lower Extremity Ischemia -- Algorithmic Approach to the Acute Cold Leg -- Myocardial Infarction -- Abdominal Aortic Aneurysm -- Dialysis Access -- Part IV. Endocrine Disorders -- Thyroid Nodules and Malignancy -- Cushing's Syndrome -- Hyperthyroidism -- Hypercalcemia -- Insulinoma -- Gastrinoma -- Surgical Hypertension: Evaluation and Treatment -- Incidentalomas -- Part V. Abdomen -- Upper Gastrointestinal Hemorrhage -- Dysphagia -- Esophageal Cancer -- Gastroesophageal Reflux -- Acute Pancreatitis -- Chronic Pancreatitis -- Small Bowel Obstruction -- Ulcer Disease and Helicobacter Pylori -- Ischemic Bowel -- Crohn's Disease -- Ulcerative Colitis -- Acute Appendicitis -- Diverticulitis -- Large Bowel Obstruction -- Colon Cancer -- Lower Gastrointestinal Hemorrhage -- Genetic Predisposition to Colorectal Cancer -- Rectal Cancer -- Anal Cancer -- Anorectal Pain- Rectal Bleeding -- Rectal Bleeding -- Jaundice -- Liver Mass -- Portal Hypertension -- Carcinoid Disease -- Inguinal Hernia -- Abdominal Wall Defects -- Indications for Renal Transplantation -- Indications for Liver Transplantation and Pre-transplant Evaluation -- Part VI. Surgical Oncology -- Palpable Breast Mass -- Abnormal Mammogram -- Invasive Breast Cancer -- Nipple Discharge -- Ductal Carcinoma in Situ -- Genetic Predisposition to Breast Cancer -- Melanoma -- Solitary Pulmonary Nodules -- Evaluation of the Suspicious Neck Mass -- Part VII. Pediatrics -- Hypertrophic Pyloric Stenosis -- Jaundice in the Pediatric Patient -- Pediatric Abdominal Masses -- Esophageal Atresia/Tracheoesophageal Fistula -- Intussusception -- Hirschsprung's Disease -- Necrotizing Enterocolitis -- Part VIII. Urology -- Hematuria -- Testicular Mass -- Painful Scrotum -- Part IX. Gynecology -- Acute Gynecologic Pelvic Pain -- Evaluation and Management of Adnexal Masses -- Pelvic Inflammatory Diseases -- Part X. Critical Care -- Postoperative Glucose Management -- Oliguria -- Postoperative Fever -- Postoperative Chest Pain -- Necrotizing Soft Tissue Infections -- Systemic Inflammatory Response Syndrome (SIRS) and Sepsis.
- Format
- e-Book
- Location
- Online
Communicating about Risks and Safe Use of Medicines : Real Life and Applied Research
https://libcat.nshealth.ca/en/permalink/provcat45281
Priya Bahri, editor.
--Singapore:
Adis
, c2020.
- Available Online
- View e-Book
- Location
- Online
At the core of this book lies the question how to approach medicines, risks and communication as a researcher - or anybody planning and evaluating a communication intervention, or wanting to understand communication events in private and the media. With a view to tackle current shortcomings of communication systems and processes for improved implementation, patient satisfaction and health outcomes, a multilayered approach is presented. This combines multiple data types and methods to obtain a w…
- Available Online
- View e-Book
- Other Authors
- Bahri, Priya
- Responsibility
- Priya Bahri, editor
- Place of Publication
- Singapore
- Publisher
- Adis
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xxx, 504 p.) : 32 illus., 30 illus. in color
- ISBN
- 9789811530135
- 9789811530128 (Print ed.)
- 9789811530142 (Print ed.)
- Subjects (MeSH)
- Health Communication
- Health Education
- Pharmaceutical Preparations - adverse effects
- Risk Assessment
- Specialty
- Health Education
- Pharmacy
- Abstract
- At the core of this book lies the question how to approach medicines, risks and communication as a researcher - or anybody planning and evaluating a communication intervention, or wanting to understand communication events in private and the media. With a view to tackle current shortcomings of communication systems and processes for improved implementation, patient satisfaction and health outcomes, a multilayered approach is presented. This combines multiple data types and methods to obtain a wider and deeper understanding of the major parties and their interactions, as well as the healthcare, social and political contexts of information flows, how they interfere and which impact they have. Illustrated with real life experiences of safety concerns with medicines, worldwide active experts discuss the methods and contributions their disciplines can offer. With considerations on terminologies, tabulated overviews on communication types and outcomes, a patient-centred vision and plain language for non-medical readers, the book creates a platform for multidisciplinary collaborations amongst researchers as well as practitioners from communications, healthcare, the social sciences and pharmacovigilance. Importantly, it advocates for an active role of patients and highlights the achievements and aspirations of patient organisations. Finally, the book suggests establishing an inclusive discipline of humanities and epidemiology of medicinal product risk communication to realise full research potential. The authors are driven by the curiosity for communication as the most human behaviour, and as good health is amongst the basic human needs, medicinal product risk communication is an exciting research field of high global relevance.
- Contents
- 1. A Multilayered Research Framework for Humanities and Epidemiology of Medicinal Product Risk Communication -- Part I: Medicines in Real Life as Communication Challenges -- 2. Hormonal Contraceptives: Communication for Risk Awareness and Informed Choice, or a Public Scare? -- 3. COX-2 Inhibitors: Communication of Accumulating Risk Evidence and a Product Withdrawal -- 4. Isotretinoin: Communication for Preventing Birth Defects and Alerting of an Uncertain Risk of Suicide -- 5. Pandemic Influenza Vaccines: Communication of Benefits, Risks, and Uncertainties -- Part II: Tackling the Challenges: Methods for Medicinal Product Risk Communication Research -- 6. Ethical Frameworks -- 7. The Cognitive and Behavioural Sciences -- 8. The Social Sciences -- 9. Rhetoric and Science and Technology Studies -- 10. Media Science and Practice -- 11. Social Media Research -- 12. Design Science with a Focus on User-Centred Evaluation of Written Information -- 13. Dissemination and Implementation Science -- 14. Pharmacoepidemiology -- 15. Legal Frameworks -- 16. From Passive to Active: Patients as Contributors to Medicinal Product Risk Communication Research.
- Format
- e-Book
- Location
- Online
Essential writings in violence risk assessment and management
https://libcat.nshealth.ca/en/permalink/provcat23410
Bloom, Hy.
--Toronto, ON:
Centre for Addiction and Mental Health
, 2007.
- Call Number
- W 740 B655e 2007
- Location
- Nova Scotia Hospital
- Call Number
- W 740 B655e 2007
- Author
- Bloom, Hy
- Other Authors
- Webster, Christopher
- Place of Publication
- Toronto, ON
- Publisher
- Centre for Addiction and Mental Health
- Date of Publication
- 2007
- Physical Description
- 612 p.
- ISBN
- 9780888685896
- Subjects (MeSH)
- Violence
- Forensic Psychiatry
- Risk Assessment
- Format
- Book
- Location
- Nova Scotia Hospital
- Loan Period
- 3 weeks
General surgery risk reduction
https://libcat.nshealth.ca/en/permalink/provcat33562
Brendon J. Coventry, editor.
--London:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Written by internationally acclaimed specialists, General Surgery Risk Reduction expands on complications associated with surgery and how to reduce them, the availability of relevant information and the rapid advancements of surgical technology. Chapters provide pertinent and concise procedure descriptions creating a book that is both comprehensive and accessible. Stages of operative approaches with relevant technical considerations are outlined in an easily understandable manner. Complications…
- Available Online
- View e-Book
- Other Authors
- Coventry, Brendon J
- Responsibility
- Brendon J. Coventry, editor
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xxii, 345 pages)
- Series Title
- Surgery : complications, risks and consequences
- ISBN
- 9781447153917 (electronic bk.)
- 9781447153900
- Subjects (MeSH)
- Intraoperative Complications - prevention & control
- Medical Errors - prevention & control
- Risk Assessment
- Subjects (LCSH)
- Surgery - Complications - Prevention
- Surgical errors - Prevention
- Surgery
- Abstract
- Written by internationally acclaimed specialists, General Surgery Risk Reduction expands on complications associated with surgery and how to reduce them, the availability of relevant information and the rapid advancements of surgical technology. Chapters provide pertinent and concise procedure descriptions creating a book that is both comprehensive and accessible. Stages of operative approaches with relevant technical considerations are outlined in an easily understandable manner. Complications are reviewed when appropriate for the organ system and problem. The text is illustrated throughout by line drawings and photographs that depict anatomic or technical principles. Forming part of the series, Surgery: Complications, Risks and Consequences, this volume General Surgery Risk Reduction provides a valuable resource for all general surgeons and residents in training. Other healthcare providers will also find this a useful resource.
- Contents
- 1. Introduction -- 2. General Perioperative Complications -- 3. Surgical Infection -- 4. Preoperative Risk Assessment and Intraoperative Monitoring -- 5. Anaesthesia Complications -- 6. Intensive Care Complications -- 7. Acute Perioperative Pain: Mechanisms and Management -- 8. Systems, Safety and Quality : Harm, Error and Litigation -- 9. Risk Management and Human Factors -- 10. Medicolegal Risk Management in Surgery -- 11. Evaluation of Surgical Safety and Efficacy -- 12. Accreditation, Credentialing, Scope of Practice and Outcome Evaluation.
- Format
- e-Book
- Location
- Online
Handbook of violence risk assessment and treatment : new approaches for mental health professionals
https://libcat.nshealth.ca/en/permalink/provcat24455
Andrade, Joel T.
--New York, NY:
Springer Publishing Company
, 2009.
- Call Number
- W 740 A553h 2009
- Location
- Nova Scotia Hospital
- Call Number
- W 740 A553h 2009
- Author
- Andrade, Joel T.
- Place of Publication
- New York, NY
- Publisher
- Springer Publishing Company
- Date of Publication
- 2009
- Physical Description
- 656 p.
- ISBN
- 9780826199034
- Subjects (MeSH)
- Forensic Psychiatry
- Violence
- Risk Assessment
- Format
- Book
- Location
- Nova Scotia Hospital
- Loan Period
- 3 weeks
Helping patients understand risks : 7 simple strategies for successful communication
https://libcat.nshealth.ca/en/permalink/provcat24133
John Paling.
--Gainesville, FL:
Risk Communication Institute
, c2006.
- Call Number
- W 85 P162h 2006
- Location
- Dickson Building
- Call Number
- W 85 P162h 2006
- Author
- Paling, John
- Responsibility
- John Paling
- Place of Publication
- Gainesville, FL
- Publisher
- Risk Communication Institute
- Date of Publication
- c2006
- Physical Description
- 185 p.
- ISBN
- 9780964223608
- Subjects (MeSH)
- Risk Assessment
- Patient Education as Topic
- Physician-Patient Relations
- Notes
- Additional resources available online at: http://www.riskcomm.com/introvisualaids.html
- Format
- Book
- Location
- Dickson Building
- Copies
- 1
- Loan Period
- 3 weeks
The Illusion of Certainty : Health Benefits and Risks
https://libcat.nshealth.ca/en/permalink/provcat40567
Erik Rifkin, Edward Bouwer ; guest author, Bob Sheff.
--Boston, MA:
Springer
, c2007.
- Available Online
- View e-Book
- Location
- Online
The Illusion of Certainty: Health Benefits and Risks peels away the "veneer of certainty" which many of us attach to health risk and benefit information given to us in our daily lives. It was written and designed primarily to assist the public in comprehending and interpreting the uncertainty associated with the overwhelming amount of information on medical and environmental health risks. The book uses unique, visual presentations and case studies to explain the benefits of medical screening te…
- Available Online
- View e-Book
- Author
- Rifkin, Erik
- Other Authors
- Bouwer, Edward
- Sheff, Bob
- Responsibility
- Erik Rifkin, Edward Bouwer ; guest author, Bob Sheff
- Place of Publication
- Boston, MA
- Publisher
- Springer
- Date of Publication
- c2007
- Physical Description
- 1 online resource (xx, 239 p. : 28 illus.)
- ISBN
- 9780387485720
- 9780387485706 (print ed.)
- Subjects (MeSH)
- Environmental Health
- Health Behavior
- Risk Assessment
- Abstract
- The Illusion of Certainty: Health Benefits and Risks peels away the "veneer of certainty" which many of us attach to health risk and benefit information given to us in our daily lives. It was written and designed primarily to assist the public in comprehending and interpreting the uncertainty associated with the overwhelming amount of information on medical and environmental health risks. The book uses unique, visual presentations and case studies to explain the benefits of medical screening tests (e.g., mammography, prostate and colorectal cancer screening, cholesterol screening) and drugs (e.g., statins, VioxxäØ) and the risks associated with exposure to environmental contaminants (e.g., lead, dioxin, radon). This book will help patients and their families get more involved in making medical decisions, and citizens face critical questions about the environment. By putting the complexities of risk analysis in terms the general public can relate to, the authors are empowering people to make well-informed decisions. About the Authors: Erik Rifkin is the president of an environmental consulting firm that specializes in the characterization of ecological and human health risks from exposure to soil, water, air and sediments. His firm provides assistance and guidance to federal and state regulatory agencies and corporations regarding the nature and magnitude of environmental risks and potential remediation strategies. Dr. Rifkin's broad experience includes the communication of health risks and benefits to groups concerned with these issues. Edward J. Bouwer is Professor of Environmental Engineering at Johns Hopkins University in Baltimore, Maryland. He has extensive experience with water and soil pollution and treatment. His research provides guidance on defining and managing environmental risks and how to interpret human and ecological health risk data. Dr. Bouwer has served on several National Research Council committees that provide guidance on managing human and ecological risk Guest Author Bob Sheff, MD, received his medical training as a radiologist at UCLA and Johns Hopkins Medical Center. He spent his career praticing medicine and running one of the largest medical managed-care systems in the U.S. Now semi-retired, he devotes his time to helping non-profit organizations and individual people address their medical concerns. He lives in Columbia, Maryland. Written for: Undergraduate, graduate, medical and nursing students, engineers, government advisory agencies, research scientists, lawyers, politicians and anyone interested in risk analysis and the interpretation of risk values.
- Contents
- Part I. The Basics -- The Illusion of Certainty -- Cause and Effect vs. Risk Factors -- Reframing the Debate -- Assessing Human Health Risks from Environmental Contaminants -- The Sources of Uncertainty -- Part II. Case Studies -- VioxxTM and Heart Attacks -- Prostate Cancer Screening -- Elevated Cholesterol: A Primary Risk Factor for Heart Disease? -- Statins, Cholesterol, and Coronary Heart Disease -- Colorectal Cancer Screening -- Health Effects of Smoking -- Chlorination of Drinking Water and Health Risks -- Exposure to Residential Radon and the Risk of Lung Cancer -- Ecological Risk Assessment -- Asian Oysters in the Chesapeake Bay -- Chromium and Sediment Toxicity -- Part III. Perspectives -- The Physician's and Patient's Perspective -- Acceptable Health Benefits and Risks -- Appendices -- Appendix A: A Brief Primer on Statistical Approaches for Quantifying Uncertainty -- Appendix B: Two Clinical Studies that Evaluated Blood Serum Cholesterol as a Risk Factor for Coronary Heart Disease (CHD) -- Appendix C: Glossary.
- Format
- e-Book
- Location
- Online
Interpreting Health Benefits and Risks : A Practical Guide to Facilitate Doctor-Patient Communication
https://libcat.nshealth.ca/en/permalink/provcat33626
Erik Rifkin, Andrew Lazris.
--Cham:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
This timely guide to communication in patient-centered medicine argues for greater clarity in explaining health risks versus benefits of an array of screening tests, procedures, and drug regimens. It reviews the growing trend toward patients' involvement in their own care, particularly in terms of chronic conditions, and details approaches physicians can use to prepare patients (and themselves) for collaborative decision-making based on informed choices and meaningful knowledge. Chapters apply …
- Available Online
- View e-Book
- Author
- Rifkin, Erik
- Other Authors
- Lazris, Andrew
- Responsibility
- Erik Rifkin, Andrew Lazris
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xx, 236 p.) : 50 illus.
- ISBN
- 9783319115443
- 9783319115436 (print ed.)
- Subjects (MeSH)
- Decision Making
- Diagnostic Techniques and Procedures - adverse effects
- Patient Participation
- Physician-Patient Relations
- Risk Assessment
- Therapeutics - adverse effects
- Abstract
- This timely guide to communication in patient-centered medicine argues for greater clarity in explaining health risks versus benefits of an array of screening tests, procedures, and drug regimens. It reviews the growing trend toward patients' involvement in their own care, particularly in terms of chronic conditions, and details approaches physicians can use to prepare patients (and themselves) for collaborative decision-making based on informed choices and meaningful knowledge. Chapters apply this lens to a wide range of common interventions as contentious as estrogen replacement therapy and antibiotics, and as widely prescribed as the daily aspirin and the annual physical. With this goal in mind, the authors also introduce an innovative decision-making tool that translates risks and benefits into a clear graphic format for fewer chances of miscommunication or misunderstanding. Among the topics covered: Involving the patient in decision making; BRCT: the Benefit/Risk Characterization Theater; Breast Cancer Screening--Mammograms; Prostate Cancer Screening; Statins, cholesterol, and coronary heart disease. Physicians in family and internal medicine will find Interpreting Health Benefits and Risks: A Practical Guide to Facilitate Doctor-Patient Communication a valuable resource for communicating with patients and new possibilities for working toward their better health and health education. This book considers several common and important situations where faulty decision-making makes overtreatment a serious risk. Clear, fair, referenced, and useful information is provided. And a powerful intuitive technique is introduced which allows patient and doctor to talk as equals as they work together in the exam room. As this book is accepted and its ideas and technique are extended, I feel sure that net harm to patients will be curtailed. And what is more, the integrity of the decision-making process will be improved. --Thomas Finucane, MD, Professor of Medicine, The Johns Hopkins University School of Medicine.
- Contents
- Part I. Setting the Stage -- Shared Decision Making -- Decision Aids -- Towards a Universal Decision Aid -- Involving the Patient in Decision Making -- BRCTs -- Part II. Case Studies : Health Benefits and Risks -- Breast Cancer Screening: Mammograms -- Colon Cancer Screening with Colonoscopy -- Prostate Cancer Screening -- Screening for Lung Cancer with Spiral CT -- Health Effects of Smoking -- Exercise Stress Tests -- The Use of Warfarin in Atrial Fibrillation -- Aspirin for Prevention of Heart Disease and Stroke -- Screening for Carotid Disease in Asymptomatic Patients -- Cholesterol Screening -- Statins, Cholesterol and Coronary Heart Disease -- Annual Exam -- Screening for and Treating Dementia -- Osteoporosis: Bone Density Testing and Drug Treatment -- Osteoporosis: Calcium and Vitamin D -- Estrogen Replacement Therapy -- Vitamins and Supplements -- MRI and Back Pain -- Antibiotics in Sinusitis and Bronchitis -- Final Thoughts.
- Format
- e-Book
- Publication Type
- Case Reports
- Location
- Online
Management of the patient at high risk for breast cancer
https://libcat.nshealth.ca/en/permalink/provcat32436
Nora M. Hansen, editor.
--New York, NY:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
Management of the Patient at High Risk for Breast Cancer provides a state-of-the art review of patients who are at high risk for breast cancer, how to identify them, the tools available for risk assessment and quantification and indications for genetic counseling and testing. The book summarizes the high risk breast imaging options, including newest techniques and schedules. Pathologic evaluation of high risk lesions are featured as well as the management issues surrounding these lesions. The v…
- Available Online
- View e-Book
- Other Authors
- Hansen, Nora M
- Responsibility
- Nora M. Hansen, editor
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (x, 190 p. : 54 ill., 50 ill. in color)
- ISBN
- 9781461458913
- Subjects (MeSH)
- Breast neoplasms - genetics
- Breast neoplasms - therapy
- Risk Assessment
- Subjects (LCSH)
- Gynecology
- Surgery
- Abstract
- Management of the Patient at High Risk for Breast Cancer provides a state-of-the art review of patients who are at high risk for breast cancer, how to identify them, the tools available for risk assessment and quantification and indications for genetic counseling and testing. The book summarizes the high risk breast imaging options, including newest techniques and schedules. Pathologic evaluation of high risk lesions are featured as well as the management issues surrounding these lesions. The volume also covers the management of concomitant cancer risk and screening strategies. A concise, yet comprehensive overview of the current status of the topic, Management of the Patient at High Risk for Breast Cancer serves as a useful resource for physicians and researchers dealing with and interested in patients at high risk for breast cancer.
- Contents
- IDENTIFYING WOMEN AT HIGH RISK OF BREAST CANCER: UNDERSTANDING THE RISK MODELS -- GENETIC AND GENOMIC FACTORS IN BREAST CANCER -- BRCA MUTATION -- HIGH RISK BREAST LESIONS AND PATHOLOGIC EVALUATION -- MANAGEMENT OF HIGH RISK LESIONS -- RADIOLOGIC IMAGING FOR THE HIGH RISK PATIENT -- RISK REDUCTION STRATEGIES: MEDICAL ONCOLOGY -- RISK REDUCTION STRATEGIES: SURGICAL PERSPECTIVE -- OPTIONS AND ADVANCES IN BREAST RECONSTRUCTION -- MANAGEMENT OF CONCOMITANT CANCER RISK -- PSYCHOLOGICAL IMPLICATIONS OF TESTING POSITIVE FOR THE BRCA GENE -- THE HIGH TECH HIGH RISK CLINIC -- CURRENT AND FUTURE DIRECTION IN BASIC AND TRANSLATIONAL RESEARCH -- INDEX.
- Format
- e-Book
- Location
- Online
Medicine of the future : risk assessment, elimination or mitigation and action plans for 28 diseases and medical conditions
https://libcat.nshealth.ca/en/permalink/provcat33458
Yann Meunier.
--Cham, Switzerland:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
This book outlines risk assessments for 28 diseases and medical conditions including the following aspects: genetics, biochemistry, serology, past medical history, family history, co-morbidities, age, gender, ethnicity, nutrition and lifestyle. Recommendations are made for how to avoid, eliminate or mitigate risks. Preventing measures concerning chemical compound intake, lifestyle and nutrition are proposed. The unique content and approach of the book to chronic disease management make it a sta…
- Available Online
- View e-Book
- Author
- Meunier, Yann
- Responsibility
- Yann Meunier
- Alternate Title
- Risk assessment, elimination or mitigation and action plans for twenty eight diseases and medical conditions
- Place of Publication
- Cham, Switzerland
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xvi, 163 pages)
- ISBN
- 9783319072999 (electronic bk.)
- 9783319072982
- Subjects (MeSH)
- Chronic Disease - prevention & control
- Health Behavior
- Preventive Medicine
- Risk Assessment
- Risk Factors
- Subjects (LCSH)
- Medical innovations
- Abstract
- This book outlines risk assessments for 28 diseases and medical conditions including the following aspects: genetics, biochemistry, serology, past medical history, family history, co-morbidities, age, gender, ethnicity, nutrition and lifestyle. Recommendations are made for how to avoid, eliminate or mitigate risks. Preventing measures concerning chemical compound intake, lifestyle and nutrition are proposed. The unique content and approach of the book to chronic disease management make it a state-of-the-art reference work, addressing a missing component of medical care and reflecting the cutting edge of preventive medicine.
- Contents
- 1. Diseases and Medical Conditions -- 1.1 Abdominal Aortic Aneurysm -- 1.2 Alzheimer’s Disease -- 1.3 Atrial Fibrillation -- 1.4 Brain Aneurysm -- 1.5 Breast Cancer -- 1.6 Celiac Disease -- 1.7 Colorectal Cancer -- 1.8 Crohn’s Disease -- 1.9 Deep Venous Thrombosis -- 1.10 Diabetes Mellitus (Type 2 -- 1.11 Glaucoma -- 1.12 Graves’ Disease -- 1.13 Hemochromatosis (Primary/HFE Related) -- 1.14 Lactose Intolerance -- 1.15 Lung Cancer -- 1.16 Lupus Erythematosus (Systemic) -- 1.17 Macular Degeneration (Age Related) -- 1.18 Melanoma -- 1.19 Multiple Sclerosis -- 1.20 Myocardial Infarction -- 1.21 Obesity -- 1.22 Osteoarthritis -- 1.23 Prostate Cancer -- 1.24 Psoriasis -- 1.25 Restless Legs Syndrome -- 1.26 Rheumatoid Arthritis -- 1.27 Sarcoidosis -- 1.28 Stomach Cancer (Hereditary Diffuse Gastric Cancer) -- 2. Pointer Documents -- Appendices.
- Format
- e-Book
- Location
- Online
Multi-Criteria Decision Analysis to Support Healthcare Decisions
https://libcat.nshealth.ca/en/permalink/provcat41583
Kevin Marsh, Mireille Goetghebeur, Praveen Thokala, Rob Baltussen, editors.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
Representing the first collection on the topic, this book builds from foundations to case studies, to future prospects, providing the reader with a rich and comprehensive understanding of the use of multi-criteria decision analysis (MCDA) in healthcare. The first section of the collection presents the foundations of MCDA as it is applied to healthcare decisions, providing guidance on the ethical and theoretical underpinnings of MCDA and how to select MCDA methods appropriate to different decisi…
- Available Online
- View e-Book
- Other Authors
- Marsh, Kevin
- Goetghebeur, Mireille
- Thokala, Praveen
- Baltussen, Rob
- Responsibility
- Kevin Marsh, Mireille Goetghebeur, Praveen Thokala, Rob Baltussen, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (vi, 329 pages) : 34 illus., 14 illus. in color
- ISBN
- 9783319475400
- 9783319475387 (print ed.)
- Subjects (MeSH)
- Decision Making
- Decision Support Techniques
- Delivery of Health Care - organization & administration
- Health Planning - methods
- Risk Assessment
- Abstract
- Representing the first collection on the topic, this book builds from foundations to case studies, to future prospects, providing the reader with a rich and comprehensive understanding of the use of multi-criteria decision analysis (MCDA) in healthcare. The first section of the collection presents the foundations of MCDA as it is applied to healthcare decisions, providing guidance on the ethical and theoretical underpinnings of MCDA and how to select MCDA methods appropriate to different decision settings. Section two comprises a collection of case studies spanning the decision continuum, including portfolio development, benefit-risk assessment, health technology assessment, priority setting, resource optimisation, clinical practice and shared decision making. Section three explores future directions in the application of MCDA to healthcare and identifies opportunities for further research to support these.
- Contents
- 1. Introduction -- 2. Theoretical Foundations of Multi-Criteria Decision Analysis -- 3. Identifying Value-s: A Reflection on the Ethical Aspects of MCDA in Healthcare Decisionmaking -- 4. Incorporating Preferences and Priorities into MCDA: Selecting an Appropriate Scoring and Weighting Technique -- 5. Dealing with Uncertainty in the Analysis and Reporting of MCDA -- 6. Supporting the Project Portfolio Selection Decision of Research and Development Investments by Means of Multi-Criteria Resource Allocation Modelling -- 7. Benefit-Risk Assessment -- 8. Advancing MCDA and HTA into Coverage Decision-Making -- 9. Embedding MCDA in Priority Setting Policy Processes: Experiences from Low and Middle Income Countries -- 10. MCDA for Resource Allocation at a Local Level: an Application in the UK -- 11. Shared Decision Making -- 12. The Role of Multi-Criteria Decision Analysis (MCDA) in Health Research Priority Setting -- 13. MCDA for the Development of Clinical Practice Guidelines and for the Prioritization Clinical Research Questions -- 14. Using MCDA as a Decision aid in Health Technology Appraisal for Coverage Decisions: Opportunities, Challenges and Unresolved Questions -- 15. Beyond Value Function Methods in Multi-Criteria Decision Analysis for Health care -- 16. Best Practice for MCDA in Healthcare.
- Format
- e-Book
- Location
- Online
Oxford handbook of occupational health
https://libcat.nshealth.ca/en/permalink/provcat33484
edited by Julia Smedley, Finlay Dick, Steven Sadhra.
(2nd ed.)
--Oxford:
Oxford University Press
, 2013.
- Available Online
- View e-Book
- Location
- Online
This handbook provides a comprehensive summary of the theory & practice of occupational health. It covers the main areas of occupational exposure, ill-health & injury resulting from such exposure, & the practical issues in occupational health as well as current issues such as Gulf War Syndrome, SARS, & exposure to electromagnetic fields.
- Available Online
- View e-Book
- Other Authors
- Smedley, Julia
- Dick, Finlay
- Sadhra, Steven S
- Responsibility
- edited by Julia Smedley, Finlay Dick, Steven Sadhra
- Edition
- 2nd ed.
- Alternate Title
- Handbook of occupational health
- Occupational health
- Place of Publication
- Oxford
- Publisher
- Oxford University Press
- Date of Publication
- 2013
- Physical Description
- 1 online resource (xxviii, 915 p.)
- Series Title
- Oxford handbooks
- Oxford medical publications
- ISBN
- 9780191742941 (eISBN)
- 9780199651627
- Subjects (MeSH)
- Occupational Health - Handbooks
- Occupational Medicine - Handbooks
- Subjects (LCSH)
- Industrial hygiene
- Health risk assessment
- Abstract
- This handbook provides a comprehensive summary of the theory & practice of occupational health. It covers the main areas of occupational exposure, ill-health & injury resulting from such exposure, & the practical issues in occupational health as well as current issues such as Gulf War Syndrome, SARS, & exposure to electromagnetic fields.
- Format
- e-Book
- Location
- Online
The practical art of suicide assessment : a guide for mental health professionals and substance abuse counselors
https://libcat.nshealth.ca/en/permalink/provcat21837
Shea, Shawn Christopher.
--Hoboken, NJ:
John Wiley & Sons
, 2002.
- Call Number
- WM 401 S539p 2002
- Location
- Dickson Building
- Call Number
- WM 401 S539p 2002
- Author
- Shea, Shawn Christopher
- Place of Publication
- Hoboken, NJ
- Publisher
- John Wiley & Sons
- Date of Publication
- 2002
- Physical Description
- 316 p.
- ISBN
- 0471237612
- Format
- Book
- Location
- Dickson Building
- Copies
- 1
- Loan Period
- 3 weeks
Prostate cancer prevention
https://libcat.nshealth.ca/en/permalink/provcat33417
Jack Cuzick, Mangesh A. Thorat, editors.
--Heidelberg:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals, and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide r…
- Available Online
- View e-Book
- Other Authors
- Cuzick, J
- Thorat, Mangesh A
- Responsibility
- Jack Cuzick, Mangesh A. Thorat, editors
- Place of Publication
- Heidelberg
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (viii, 169 pages)
- Series Vol.
- v. 202
- Series Title
- Recent results in cancer research
- ISBN
- 9783642451959 (electronic bk.)
- 9783642451942
- Subjects (MeSH)
- Prostatic Neoplasms - prevention & control
- Anticarcinogenic Agents
- Chemoprevention
- Early Detection of Cancer
- Risk Factors
- Subjects (LCSH)
- Prostate - Cancer - Prevention
- Prostatic Neoplasms - prevention & control
- Risk Assessment
- Biological Markers
- Life Style
- Risk Factors
- Diet
- Chemoprevention
- Oncology
- Abstract
- Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals, and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed, and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5-reductase inhibitors, DFMO, and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease, and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.
- Contents
- The biology and natural history of prostate cancer: a short introduction -- Germline genetic variants associated with prostate cancer and potential relevance to clinical practice -- Lifestyle and dietary factors in prostate cancer prevention -- Nutrition, hormones and prostate cancer risk: results from the European prospective investigation into cancer and nutrition -- Screening for prostate cancer: current status of ERSPC and screening-related issues -- Update of the prostate, lung, colorectal, and ovarian cancer screening trial -- ERSPC, PLCO studies and critique of Cochrane review 2013 -- Screening for prostate cancer: reflecting on the quality of evidence from the ERSPC and PLCO studies -- Phase III prostate cancer chemoprevention trials -- Risk adapted chemoprevention for prostate cancer: an option? -- Aspirin and prostate cancer prevention -- Chemoprevention of prostate cancer by isoflavonoids -- Lycopene for the prevention and treatment of prostate disease -- Chemoprevention of prostate cancer with the polyamine -- Synthesis inhibitor difluoromethylornithine -- Prostate cancer prevention: agent development strategies -- Prognostic value of a cell cycle progression score for men with prostate cancer -- Distinguishing indolent from aggressive prostate cancer -- Management of low risk and low PSA prostate cancer: long term results from the prostate cancer intervention versus observation trial.
- Format
- e-Book
- Location
- Online
