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Abdominal Sepsis : A Multidisciplinary Approach

https://libcat.nshealth.ca/en/permalink/provcat43191
Massimo Sartelli, Matteo Bassetti, Ignacio Martin-Loeches, editors. --Cham: Springer , c2018.
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This book examines in detail the topic of sepsis, with a focus on intra-abdominal sepsis. Particular attention is devoted to source control in the management of the infection, antimicrobial therapy and sepsis support, which represent the cornerstones of treating patients with abdominal sepsis. The importance of a multidisciplinary approach is highlighted not only by the instructive and informative sections on the acute manifestations of appendicitis, cholecystitis, and cholangitis, perforations…
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Other Authors
Sartelli, Massimo
Bassetti, Matteo
Martin-Loeches, Ignacio
Responsibility
Massimo Sartelli, Matteo Bassetti, Ignacio Martin-Loeches, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xi, 405 p.) : 49 illus., 34 illus. in color
Series Title
Hot topics in acute care surgery and trauma
ISBN
9783319597041
9783319597034 (print ed.)
9783319597058 (print ed.)
ISSN
2520-8284
Subjects (MeSH)
Digestive System Diseases - microbiology
Drug Resistance, Microbial
Intraabdominal Infections - diagnosis
Intraabdominal Infections - therapy
Sepsis - therapy
Specialty
Gastroenterology
Infectious Disease Medicine
Abstract
This book examines in detail the topic of sepsis, with a focus on intra-abdominal sepsis. Particular attention is devoted to source control in the management of the infection, antimicrobial therapy and sepsis support, which represent the cornerstones of treating patients with abdominal sepsis. The importance of a multidisciplinary approach is highlighted not only by the instructive and informative sections on the acute manifestations of appendicitis, cholecystitis, and cholangitis, perforations and diverticulitis, Clostridium difficile infection and the role of candida in abdominal sepsis, but also by an extensive discussion of issues including antimicrobial resistance, damage control surgery, principles of antimicrobial therapy, hemodynamic support, adjunctive therapies, and thromboprophylaxis. Abdominal sepsis is the host's systemic inflammatory response to intra-abdominal infections. It is associated with significant morbidity and mortality rates, and represents the second most common cause of sepsis-related mortality at intensive care units. Gathering contributions by authoritative experts from all around the world, this book will allow acute care surgeons, abdominal surgeons, intensive care clinicians, and students to broaden their understanding of intra-abdominal sepsis in daily clinical practice.
Contents
1. Classifications and principles of treatment -- 2. Peritonitis and intra-peritoneal inflammatory mediators -- 3. Imaging diagnosis -- 4. Higk risk patients and prognostic factors -- 5. Acute appendicitis -- 6. Acute cholecystitis -- 7. Acute cholangitis -- 8 Pyogenic liver abscess -- 9. Gastroduodenal perforations -- 10. Small bowel perforations -- 11. Acute colonic diverticulitis -- 12. Post-operative peritonitis -- 13. Damage control surgery in managing abdominal sepsis -- 14. Ongoing peritonitis -- 15. Clostridium difficile infection -- 16. Complicated Intra-abdominal infections: Principles of Antimicrobial Therapy -- 17. Antimicrobial armamentarium -- 18. Antimicrobial resistance in intra-abdominal infections -- 19. The role of candida in abdominal sepsis -- 20. Use and interpretation of peritoneal swabs -- 21. Appropriate antimicrobial therapy in critically ill patients -- 22. Haemodynamic support -- 23. Adjunctive therapies -- 24. Impact and management of abdominal compartment syndrome in patients with abdominal sepsis -- 25. Tromboprohilaxis in patients with abdominal sepsis -- 26. Nutrition in patients with abdominal sepsis.
Format
e-Book
Location
Online
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Handbook of Sepsis

https://libcat.nshealth.ca/en/permalink/provcat43280
W. Joost Wiersinga, Christopher W. Seymour, editors. --Cham: Springer , c2018.
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This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as…
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Other Authors
Wiersinga, W. Joost
Seymour, Christopher W.
Other Authors
European Sepsis Academy
European Society of Clinical Microbiology and Infectious Diseases
ESGBIS (ESMID Study Group for Bloodstream Infections and Sepsis)
Responsibility
W. Joost Wiersinga, Christopher W. Seymour, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (viii, 267 p.) : 22 illus., 19 illus. in color
ISBN
9783319735061
9783319735054 (print ed.)
9783319735078 (print ed.)
Subjects (MeSH)
Sepsis
Specialty
Infectious Disease Medicine
Abstract
This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is international in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.
Contents
Part I. SEPSIS: AN OVERVIEW -- 1. What is sepsis? -- 2. The epidemiology of sepsis -- Part II. THE PATHOGENESIS OF SEPSIS -- 3. The pathogenesis -- 4. The coagulation system in sepsis -- 5. The endocrine system in sepsis -- 6. Biomarkers for sepsis -- Part III. SEPSIS MANAGEMENT -- 7. International clinical practice guidelines -- 8. Fluids -- 9. Vasopressors -- 10. Multiorgan failure -- 11. Importance of the pathogen -- 12. Antimicrobial therapy -- 13. Adjunctive immunotherapy -- Part IV. SEPSIS IN THE COMING DECADE -- 14. Novel trial design in sepsis -- 15. Sepsis in low- and middle income countries -- 16. Sepsis: the road ahead.
Format
e-Book
Location
Online
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Management of sepsis : the PIRO approach

https://libcat.nshealth.ca/en/permalink/provcat24193
Relio, Jordi. --Berlin, Germany: Springer , 2009.
Call Number
WC 240 M266 2009
Location
Halifax Infirmary
Call Number
WC 240 M266 2009
Author
Relio, Jordi
Other Authors
Diaz, Emili
Rodriguez, Alejandro
Place of Publication
Berlin, Germany
Publisher
Springer
Date of Publication
2009
Physical Description
163 p.
ISBN
978364004780
Subjects (MeSH)
Sepsis - therapy
Systemic inflammatory response syndrome - therapy
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Management of Sepsis : The PIRO Approach

https://libcat.nshealth.ca/en/permalink/provcat28329
edited by Jordi Rello, Emili Díaz, Alejandro Rodríguez. --Berlin, Heidelberg: Springer , c2009.
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Online
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Author
Rello, Jordi
Other Authors
Díaz, Emili
Rodríguez, Alejandro
Responsibility
edited by Jordi Rello, Emili Díaz, Alejandro Rodríguez
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2009
ISBN
9783642004797
Subjects (MeSH)
Sepsis - therapy
Subjects (LCSH)
Infectious diseases
Critical care medicine
Format
e-Book
Location
Online
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Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery

https://libcat.nshealth.ca/en/permalink/provcat30361
edited by Edward Abraham, Mervyn Singer. --Berlin, Heidelberg: Springer-Verlag , c2007.
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Location
Online
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Author
Abraham, Edward
Other Authors
Singer, Mervyn
Responsibility
edited by Edward Abraham, Mervyn Singer
Place of Publication
Berlin, Heidelberg
Publisher
Springer-Verlag
Date of Publication
c2007
Series Vol.
44
Series Title
Update in intensive care and emergency medicine
ISBN
9783540303282
Subjects (MeSH)
Sepsis - complications
Multiple Organ Failure - etiology
Critical Care - methods
Subjects (LCSH)
Infectious diseases
Critical care medicine
Format
e-Book
Location
Online
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Guillermo Ortiz-Ruiz, Carmelo Dueñas-Castell, editors. (Third edition) --New York, NY: Springer , c2018.
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The new edition of this volume features a concise yet comprehensive review of sepsis. In addition to thoroughly revised chapters from the previous edition that covers the latest in diagnostics, therapeutics, and antimicrobials, the third edition features new chapters on the economic impact of infections and antibiotics, multi-organ failure in sepsis, and current strategies for training high-performance teams. Written by an international group of experts in the field, Sepsis, Third Edition is a …
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Other Authors
Ortiz-Ruiz, Guillermo
Dueñas-Castell, Carmelo
Responsibility
Guillermo Ortiz-Ruiz, Carmelo Dueñas-Castell, editors
Edition
Third edition
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xii, 171 p.) : 30 illus., 15 illus. in color
ISBN
9781493973347
9781493973323 (print ed.)
9781493973330 (print ed.)
Subjects (MeSH)
Drug Resistance, Microbial
Sepsis
Specialty
Infectious Disease Medicine
Abstract
The new edition of this volume features a concise yet comprehensive review of sepsis. In addition to thoroughly revised chapters from the previous edition that covers the latest in diagnostics, therapeutics, and antimicrobials, the third edition features new chapters on the economic impact of infections and antibiotics, multi-organ failure in sepsis, and current strategies for training high-performance teams. Written by an international group of experts in the field, Sepsis, Third Edition is a valuable resource that provides the most practical information for clinicians and practitioners who treat this complication in the ICU.
Contents
Sepsis: A Definition Under Construction -- Economic Impact of Infections and Antibiotics -- Immunity in Sepsis -- Biomarkers in Sepsis -- Diagnostic Imaging in Sepsis of Pulmonary Origin -- Multiorgan System Failure in Sepsis -- Resistance Mechanisms: A Problem and an Approach to the Solution -- Interpreted Reading of the Antibiogram: A Tool in the Clinical Practice -- Sepsis Management: Non Antibiotic Treatment of Sepsis and Septic Shock -- New Strategies for Training High-Performance Teams -- Simulation and Sepsis: What is the Best Evidence?
Format
e-Book
Location
Online
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edited by Guillermo Ortiz-Ruiz, Marco A. Perafán, Eugen Faist, Carmelo Dueñas Castell. (2nd ed.) --New York, NY: Springer Science+Business Media , c2006.
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Location
Online
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Author
Ortiz-Ruiz, Guillermo
Other Authors
Perafán, Marco A
Faist, Eugen
Castell, Carmelo Dueñas
Responsibility
edited by Guillermo Ortiz-Ruiz, Marco A. Perafán, Eugen Faist, Carmelo Dueñas Castell
Edition
2nd ed.
Place of Publication
New York, NY
Publisher
Springer Science+Business Media
Date of Publication
c2006
ISBN
9780387345741
Subjects (MeSH)
Sepsis - therapy
Sepsis - complications
Critical Care - methods
Subjects (LCSH)
Infectious diseases
Critical care medicine
Format
e-Book
Location
Online
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edited by Simon V. Baudouin. --London: Springer , c2008.
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Location
Online
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Author
Baudouin, Simon V
Responsibility
edited by Simon V. Baudouin
Place of Publication
London
Publisher
Springer
Date of Publication
c2008
Series Title
Competency-Based Critical Care
ISBN
9781846289392
Subjects (MeSH)
Sepsis
Subjects (LCSH)
Infectious diseases
Critical care medicine
Format
e-Book
Location
Online
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Sepsis and non-infectious systemic inflammation : from biology to critical care

https://libcat.nshealth.ca/en/permalink/provcat24214
Cavaillon, Jean-Marc. --Weinheim, Germany: Wiley-VCH , 2009.
Call Number
WC 240 S479 2009
Location
Halifax Infirmary
Call Number
WC 240 S479 2009
Author
Cavaillon, Jean-Marc
Other Authors
Adrie, Christophe
Place of Publication
Weinheim, Germany
Publisher
Wiley-VCH
Date of Publication
2009
Physical Description
425 p.
ISBN
9783527319350
Subjects (MeSH)
Sepsis - physiopathology
Sepsis - therapy
Systemic inflammatory response syndrome - physiopathology
Systemic inflammatory response syndrome - therapy
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Sepsis : Definitions, Pathophysiology and the Challenge of Bedside Management

https://libcat.nshealth.ca/en/permalink/provcat41598
Nicholas S. Ward, Mitchell M. Levy, editors. --Cham: Humana Press , 2017.
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This book is designed to provide a comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike, . Patients with severe sepsis requiring ICU admission have very high rates of ICU and overall hospital mortality, with estimates ranging from 18 to 50%. Risk factors for death from sepsis include underlying illness, increased age, and multi-system organ failure. This is compounded by the significant variation in the management of early sev…
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Other Authors
Ward, Nicholas S
Levy, Mitchell M
Responsibility
Nicholas S. Ward, Mitchell M. Levy, editors
Place of Publication
Cham
Publisher
Humana Press
Date of Publication
2017
Physical Description
1 online resource (xi, 271 pages) : 16 illus., 8 illus. in color
Series Title
Respiratory medicine
ISBN
9783319484709
9783319484686 (print ed.)
ISSN
2197-7372
Subjects (MeSH)
Sepsis
Abstract
This book is designed to provide a comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike, . Patients with severe sepsis requiring ICU admission have very high rates of ICU and overall hospital mortality, with estimates ranging from 18 to 50%. Risk factors for death from sepsis include underlying illness, increased age, and multi-system organ failure. This is compounded by the significant variation in the management of early severe sepsis. Care of these patients and clinical conditions can be quite complex, and materials are collected from the most current, evidence-based resources. Book sections have been structured to review the overall definitions and epidemiology of sepsis as well as current insights into the pathophysiology of sepsis. This review summarizes the evidence for the international consensus guidelines for the identification and management of sepsis. The latter part of this book reviews emerging concepts and approaches in the diagnosis and management of sepsis that may significantly reduce mortality in the future. Sepsis: Pathophysiology, Definitions and the Challenge of Bedside Management represents a collaboration between authors drawn from a variety of disciplines and contributions from basic scientists and highly recognized clinical opinion leaders with expertise in clinical trials.
Contents
Part I -- 1. Introduction -- 2. Sepsis Definitions -- 3. Epidemiology of Sepsis: Current Data and Predictions for the Future -- Part II -- 4. Overview of the Molecular Pathways and Mediators of Sepsis -- 5. Sepsis-induced Immune Suppression -- 6. Molecular Targets for Therapy -- Section 3 -- 7. Mechanisms of Organ Dysfunction in Sepsis -- Chapter 8 Sepsis-Induced AKI -- 9. Sepsis and the Lung -- 10. Organ Dysfunction in Sepsis: Brain, Neuromuscular, Cardiovascular, and Gastrointestinal -- Part IV -- 11. Diagnosis of Sepsis: Clinical Findings and the Role of Biomarkers -- 12. Source Control in Sepsis -- 13. Hemodynamic Support in Sepsis -- 14. Bundled Therapies in Sepsis -- 15. Genetics in the Prevention and Treatment of Sepsis.
Format
e-Book
Location
Online
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Sepsis Management in Resource-limited Settings

https://libcat.nshealth.ca/en/permalink/provcat44148
Arjen M. Dondorp, Martin W. Dünser, Marcus J. Schultz, editors. --Cham: SpringerOpen , 2019.
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Access
Open access
Location
Online
This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in lo…
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Other Authors
Dondorp, Arjen M.
Dünser, Martin W.
Schultz, Marcus J.
Other Authors
European Society of Intensive Care Medicine. Global Intensive Care Working Group
Mahidol-Oxford Tropical Medicine Research Unit
Responsibility
Arjen M. Dondorp, Martin W. Dünser, Marcus J. Schultz, editors
Place of Publication
Cham
Publisher
SpringerOpen
Date of Publication
2019
Physical Description
1 online resource (xv, 216 p.) : 8 illus., 6 illus. in color
ISBN
9783030031435
9783030031428 (Print ed.)
9783030031442 (Print ed.)
Subjects (MeSH)
Medically Underserved Area
Sepsis - prevention & control
Tropical Medicine
Specialty
Critical Care
Abstract
This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.
Contents
1. Current Challenges in the Management of Sepsis in ICUs in Resource–poor Settings and Suggestions for the Future -- 2. Development of the Guidelines: Focus on Availability, Feasibility, Affordability and Safety of Interventions in Resource–limited Settings -- 3. Infrastructure and Organization of Adult Intensive Care Units in Resource–limited settings -- 4. Recognition of Sepsis in Resource-limited Settings -- 5. Core Elements of General Supportive Care for Patients with Sepsis and Septic Shock in Resource–limited Settings -- 6. Ventilatory Support of Patients with Sepsis or Septic Shock in Resource–limited Settings -- 7. Hemodynamic Assessment and Support in Sepsis and Septic Shock in Resource–limited Settings -- 8. Infection Management in Patients with Sepsis and Septic Shock in Resource–limited Settings -- 9. Management of Severe Malaria and Severe Dengue in Resource-limited Settings -- 10. Pediatric Sepsis and Septic Shock Management in Resource–limited Settings.
Access
Open access
Format
e-Book
Location
Online
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Sepsis Management : PIRO and MODS

https://libcat.nshealth.ca/en/permalink/provcat31088
Jordi Rello, Jeffrey Lipman, Thiago Lisboa, editors. --Berlin, Heidelberg: Springer , c2012.
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Online
This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing i…
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Other Authors
Rello, Jordi
Lipman, Jeffrey
Lisboa, Thiago
Responsibility
Jordi Rello, Jeffrey Lipman, Thiago Lisboa, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (vi, 243 p. : 18 ill., 8 ill. in color)
ISBN
9783642035197
Subjects (MeSH)
Multiple Organ Failure - prevention & control
Sepsis - prevention & control
Sepsis - therapy
Subjects (LCSH)
Critical care medicine
Infectious diseases
Abstract
This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.
Contents
Multiorgan Dysfunction Syndrome (MODS): What is New? -- MODS Scores: Which One Should I Use? -- Why Guidelines Require Reform -- PIRO Concept and Clinical Failure -- PIRO-Based Approach for Sepsis in Immunocompromised Patients: What’s Different? -- Intra-Abdominal Hypertension and MODS -- Assessing Renal Dysfunction in Septic Patients -- Monitoring Myocardial Dysfunction as Part of Sepsis Management -- The Lung in Multiorgan Failure -- Pathogens in Severe Sepsis: New Paradigms for Gram-Positive Treatment -- Pathogens in Severe Sepsis: New Paradigms for Fungi Treatment -- Importance of High Creatinine Clearance for Antibacterial Treatment in Sepsis -- How do I Adjust Antimicrobial Daily Dosage in Patients with MODS? A Pharmacist’s Contribution -- Improving Outcomes in Sepsis and Septic Shock: Getting it Right the First Time.
Format
e-Book
Location
Online
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Sepsis : New Strategies for Management

https://libcat.nshealth.ca/en/permalink/provcat30194
edited by Jordi Rello, Marcos I. Restrepo. --Berlin, Heidelberg: Springer , c2008.
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Location
Online
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Author
Rello, Jordi
Other Authors
Restrepo, Marcos I
Responsibility
edited by Jordi Rello, Marcos I. Restrepo
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2008
ISBN
9783540790013
Subjects (MeSH)
Sepsis - therapy
Subjects (LCSH)
Infectious diseases
Critical care medicine
Format
e-Book
Location
Online
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Sepsis : new strategies for management

https://libcat.nshealth.ca/en/permalink/provcat24200
Rello, Jordi. --Berlin, Germany: Springer , 2008.
Call Number
WC 240 S479 2008
Location
Halifax Infirmary
Call Number
WC 240 S479 2008
Author
Rello, Jordi
Other Authors
Restrepo, Marcos I
Place of Publication
Berlin, Germany
Publisher
Springer
Date of Publication
2008
Physical Description
142 p.
ISBN
9783540790006
Subjects (MeSH)
Sepsis - etiology
Sepsis - therapy
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Severe Trauma and Sepsis : Organ Damage and Tissue Repair

https://libcat.nshealth.ca/en/permalink/provcat44438
Xiaobing Fu, Liangming Liu, editors. --Singapore: Springer , c2019.
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Online
This book discusses recent progress in organ damage and tissue repair following severe trauma and sepsis. In part 1, it introduces the theory and clinical practice in organ damage. In part 2, it covers all the subjects of sepsis, ranging from mechanism, inflammation, and infection to the lung injury and neonatal sepsis. In part 3, it discusses 4 new advances techniques in tissue repair. There are 20 chapters contributed by experts in each area. This book is a valuable reference for scientists a…
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Other Authors
Fu, Xiaobing
Liu, Liangming
Responsibility
Xiaobing Fu, Liangming Liu, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (xv, 389 p.) : 27 illus., 26 illus. in color
ISBN
9789811333538
9789811333521 (Print ed.)
9789811333545 (Print ed.)
Subjects (MeSH)
Sepsis - physiopathology
Sepsis - therapy
Wounds and Injuries - complications
Specialty
Traumatology
Abstract
This book discusses recent progress in organ damage and tissue repair following severe trauma and sepsis. In part 1, it introduces the theory and clinical practice in organ damage. In part 2, it covers all the subjects of sepsis, ranging from mechanism, inflammation, and infection to the lung injury and neonatal sepsis. In part 3, it discusses 4 new advances techniques in tissue repair. There are 20 chapters contributed by experts in each area. This book is a valuable reference for scientists and clinicians to know the new knowledge and technology in severe trauma and sepsis, which will benefit their work in research and clinic through multidisciplinary collaboration.
Contents
1. Damage Control in Abdominal Compartment Syndrome -- 2. Damage Control Resuscitation -- 3. Perioperative Intestinal Injury: Etiology, Mechanism, and Prevention -- 4. The Role of Mitochondrial Quality Imbalance in Multiple Organ Dysfunction Syndrome Following Severe Trauma, Shock, and Sepsis -- 5. Lymph Formation and Transport: Role in Trauma-Hemorrhagic Shock -- 6. Cardiac Autonomic Nervous System and Sepsis-Induced Cardiac Dysfunction -- 7. Role of TLR4 in Sepsis -- 8. Pro-resolution of Inflammation: New Hints to Manage Sepsis? -- 9. Novel Insights into Anti-inflammatory Therapy in Sepsis-Induced ARDS -- 10. Surviving Sepsis: Tolerance Towards Bacteria and Their Cell Wall Components -- 11. New Progress of Goal-Directed Fluid Resuscitation for Septic Shock -- 12. Secondary Infection in Sepsis: Clinical Significance, Immune Mechanism, and Therapy Strategies -- 13. Research Progress of Burn Infection -- 14. Modulation of HMGB1 Release for Treating Lethal Infection and Injury -- 15. Sepsis-Induced Lung Injury: The Mechanism and Treatment -- 16. Progress of Research in Neonatal Sepsis -- 17. Advances in Stem Cell Research in Sepsis -- 18. Stem Cell-Based Therapies for Acute Lung Injury and Acute Respiratory Distress Syndrome -- 19. Advanced Techniques in Burn Wound Repair -- 20. Plasticity of Epidermal Stem Cells: The Future of Stem Cell-Based Therapeutics to Improve Cutaneous Wound Healing.
Format
e-Book
Location
Online
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