Acute Ischemic Stroke : Imaging and Intervention
https://libcat.nshealth.ca/en/permalink/provcat28858
edited by R. Gilberto González, Joshua A. Hirsch, Michael H. Lev, Pamela W. Schaefer, Lee H. Schwamm.
(2nd ed.)
--Berlin, Heidelberg:
Springer-Verlag
, c2011.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- González, R. Gilberto
- Other Authors
- Hirsch, Joshua A
- Lev, Michael H
- Schaefer, Pamela W
- Schwamm, Lee H
- Responsibility
- edited by R. Gilberto González, Joshua A. Hirsch, Michael H. Lev, Pamela W. Schaefer, Lee H. Schwamm
- Edition
- 2nd ed.
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer-Verlag
- Date of Publication
- c2011
- ISBN
- 9783642127519
- Subjects (MeSH)
- Brain Ischemia - diagnostic imaging
- Stroke - diagnostic imaging
- Stroke - therapy
- Radiography
- Subjects (LCSH)
- Neurology
- Diagnostic Imaging
- Format
- e-Book
- Location
- Online
Cell-based therapies in stroke
https://libcat.nshealth.ca/en/permalink/provcat32520
Jukka Jolkkonen, Piotr Walczak, editors.
--Heidelberg:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
Stroke remains one of the main causes of death and disability worldwide. Effective therapy for stroke recovery remains an unmet need. Much hope and promises are placed on cell-based therapies. The aim of this book is to provide focused yet comprehensive reviews on the current state of cell-based approaches in the treatment of stroke. The topics covered include experimental data on functional outcome after intravascular and intracerebral delivery of cells in stroke animals, followed by translat…
- Available Online
- View e-Book
- Other Authors
- Jolkkonen, Jukka
- Walczak, Piotr
- Responsibility
- Jukka Jolkkonen, Piotr Walczak, editors
- Place of Publication
- Heidelberg
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (viii, 204 p. : 24 ill., 20 ill. in color)
- ISBN
- 9783709111758
- Subjects (MeSH)
- Stroke - therapy
- Tissue Therapy
- Subjects (LCSH)
- Neurosciences
- Radiology, Medical
- Neurology
- Abstract
- Stroke remains one of the main causes of death and disability worldwide. Effective therapy for stroke recovery remains an unmet need. Much hope and promises are placed on cell-based therapies. The aim of this book is to provide focused yet comprehensive reviews on the current state of cell-based approaches in the treatment of stroke. The topics covered include experimental data on functional outcome after intravascular and intracerebral delivery of cells in stroke animals, followed by translational chapters which will rely heavily on the use of different imaging modalities in the tracking of cells. The last and most challenging part will describe the early phase of clinical studies, providing guidelines for future research and clinical applications. Clearly and concisely written, this text will be a useful resource for neurologists, radiologists, and neuroscientists interested in cell transplantation as a therapeutic strategy for stroke patients.
- Contents
- Part I. Preclinical Optimization of Cell Therapies -- Part II. Translational Imaging Techniques to Study Cell Therapy -- Part III. Early Phase Clinical Studies -- Index.
- Format
- e-Book
- Location
- Online
Cell Therapy Against Cerebral Stroke : Comprehensive Reviews for Translational Researches and Clinical Trials
https://libcat.nshealth.ca/en/permalink/provcat41920
Kiyohiro Houkin, Koji Abe, Satoshi Kuroda, editors.
--Tokyo:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book presents comprehensive reviews for both translational research and clinical trials on cell therapy for stroke. Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating…
- Available Online
- View e-Book
- Other Authors
- Houkin, Kiyohiro
- Abe, Koji
- Kuroda, Satoshi
- Responsibility
- Kiyohiro Houkin, Koji Abe, Satoshi Kuroda, editors
- Place of Publication
- Tokyo
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (x, 156 pages) : 15 illus., 11 illus. in color
- ISBN
- 9784431560593
- 9784431560579 (print ed.)
- Abstract
- This book presents comprehensive reviews for both translational research and clinical trials on cell therapy for stroke. Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating disease and ischemic stroke, as the injured neural tissue in the CNS has only a limited regenerative capacity. Recently, a growing body of evidence in this field suggests that cell transplantation holds great potential as a form of stroke therapy. The authors, who are experts in the field of neurosurgery, review and discuss optimal cell sources and various issues involved in translational research; further, they outline ongoing clinical trials in Japan.
- Contents
- Part I. Optimal Cell Cources -- 1. Bone Marrow-Derived Mononuclear Cells -- 2. Cell Therapy for Ischemic Stroke with Bone Marrow Stromal Cells -- 3. Neural Stem Cells/Neuronal Progenitor Cells -- 4. iPS Cells and iN Cells -- Part II. Translational Researches -- 5. Cell Culture -- 6. Route, Cell Dose, and Timing -- 7. Role of Biomaterials as Scaffolding in Cell Therapy for Stroke -- 8. In Vivo Cell Tracking Techniques for Applications in Central Nervous System Disorders -- 9. Functional Bio-imaging -- Part III. Clinical Trials -- 10. Review of Previous Clinical Trials and Guidelines of Cell Therapy -- 1.1 Intravenous Autologous Bone Marrow Mononuclear Cell Transplantation for Stroke Patients -- 12. Mesenchymal Stem Cells.
- Format
- e-Book
- Location
- Online
Cellular and Molecular Approaches to Regeneration and Repair
https://libcat.nshealth.ca/en/permalink/provcat42771
Paul A. Lapchak, John H. Zhang, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book discusses recent advances in the field of translational stroke research. The editors have designed the book to provide new insight into the importance of regeneration and repair mechanisms for stroke victims. The editors have brought together a talented group of international stroke researchers and clinicians to contribute to this volume, which is written for students, researchers and physicians in biotechnology, neurosciences, neurology, neuroradiology and neurosurgery. Throughout th…
- Available Online
- View e-Book
- Other Authors
- Lapchak, Paul A.
- Zhang, John H.
- Responsibility
- Paul A. Lapchak, John H. Zhang, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (vii, 541 p.) : 46 illus., 45 illus. in color
- Series Title
- Springer series in translational stroke research
- ISBN
- 9783319666792
- 9783319666785 (print ed.)
- 9783319666808 (print ed.)
- 9783319882994 (print ed.)
- ISSN
- 2363-958X
- Specialty
- Neurology
- Regenerative Medicine
- Abstract
- This book discusses recent advances in the field of translational stroke research. The editors have designed the book to provide new insight into the importance of regeneration and repair mechanisms for stroke victims. The editors have brought together a talented group of international stroke researchers and clinicians to contribute to this volume, which is written for students, researchers and physicians in biotechnology, neurosciences, neurology, neuroradiology and neurosurgery. Throughout the world, stroke is still a leading cause of mortality and morbidity; there are 152,000 strokes in the United Kingdom, 62,000 in Canada, and approximately 15 million people worldwide. Large communities of stroke survivors are eagerly awaiting scientific advances in translational stroke research related to regeneration and recovery of function that would offer new therapeutics for rehabilitation and regeneration utilizing novel stem cell and molecular-based approaches. This volume will allow the reader to understand the future of stroke treatment from its inception in the laboratory through to clinical trial design. The reader will learn about the recent advances made in these areas related to basic and applied stroke research and their translational potential. Dr. Paul A. Lapchak is Professor of Neurology and Director of Translational Research in the Departments of Neurology & Neurosurgery at Cedars-Sinai Medical Center in Los Angeles CA, USA. Dr. Lapchak is an internationally recognized expert conducting translational drug development research for ischemic and hemorrhagic stroke. Dr. John H. Zhang is Professor of Anesthesiology, Neurosurgery, Neurology, and Physiology, and Director, Center for Neuroscience Research at Loma Linda University School of Medicine, Loma Linda, CA, USA. Dr. Zhang is an internationally recognized expert working on drug development for hemorrhagic stroke.
- Format
- e-Book
- Location
- Online
Cellular Therapy for Stroke and CNS Injuries
https://libcat.nshealth.ca/en/permalink/provcat39128
Li-Ru Zhao, John H. Zhang, editors.
--Cham:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
The first book to focus on cellular therapy for stroke and other CNS injuries. Addresses recent research on all relevant cell types including neural stem cells, bone marrow stem cells, endothelial progenitor cells, and many others that have had protective or regenerative effects in animal models. Cellular therapy for stroke and neural trauma has gained worldwide attention during the last decade and has shown some promising results. The book also provides information on cell isolation and cultur…
- Available Online
- View e-Book
- Other Authors
- Zhao, Li-Ru
- Zhang, John H
- Responsibility
- Li-Ru Zhao, John H. Zhang, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xvi, 337 p. : 22 illus., 20 illus. in color)
- Series Title
- Springer series in translational stroke research
- ISBN
- 9783319114811
- 9783319114804 (print ed.)
- Subjects (MeSH)
- Cell- and Tissue-Based Therapy
- Central Nervous System - injuries
- Cerebrovascular Disorders - therapy
- Stroke - therapy
- Abstract
- The first book to focus on cellular therapy for stroke and other CNS injuries. Addresses recent research on all relevant cell types including neural stem cells, bone marrow stem cells, endothelial progenitor cells, and many others that have had protective or regenerative effects in animal models. Cellular therapy for stroke and neural trauma has gained worldwide attention during the last decade and has shown some promising results. The book also provides information on cell isolation and culture skills, transplantation methods, and neurological functional evaluations.
- Contents
- Part I. Stem Cell Research in Stroke -- 1 Basic Studies on Neural Stem Cells in the Brain -- 2 Neural Stem Cells in Response to Microenvironment Changes Inside and Outside of the Brain -- 3 The Role of Endogenous Neural Stem Cells in Stroke -- 4 Bone Marrow Mesenchymal Stromal Cell Transplantation: A Neurorestorative Therapy for Stroke -- 5 Cord Blood as a Treatment for Stroke -- 6 The Role of Endothelial Progenitor Cells in Stroke -- 7 Endothelial Progenitor Cell Therapy in Stroke -- 8 Adipose-Derived Stem Cells: Isolation and Culturing -- 9 Transplantation of Adipose-Derived Stem Cells in Stroke -- Part II. Stem Cell Research in CNS Injuries -- 10 Endogenous Neurogenesis After Traumatic Brain Injury -- 11 The Contribution of Mesenchymal Stromal Cells in Traumatic Brain Injury -- 12 Transplantation of Embryonic Stem Cells in Traumatic Brain Injury -- 13 Transplantation of Olfactory Ensheathing Cells in Spinal Cord Injury -- 14 Characterization of the Phenotypic Features, Immuno-modulatory Properties and Therapeutic Potentials of Wharton’s Jelly-Derived Mesenchymal Stromal Cells.
- Format
- e-Book
- Location
- Online
Hemorrhagic Stroke
https://libcat.nshealth.ca/en/permalink/provcat41314
Edoardo Boccardi, Marco Cenzato, Francesco Curto, Marco Longoni, Cristina Motto, Valentina Oppo, Valentina Perini, Simone Vidale.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book provides detailed practical guidance on the management of hemorrhagic stroke in the clinical settings encountered in daily practice. Real-life cases are used to depict a wide range of clinical scenarios and to highlight significant aspects of management of hemorrhagic stroke. In addition, diagnostic and therapeutic protocols are presented and helpful decision-making algorithms are provided that are specific to the different professionals involved in delivery of stroke care and to diff…
- Available Online
- View e-Book
- Author
- Boccardi, Edoardo
- Other Authors
- Cenzato, Marco
- Curto, Francesco
- Longoni, Marco
- Motto, Cristina
- Oppo, Valentina
- Perini, Valentina
- Vidale, Simone
- Responsibility
- Edoardo Boccardi, Marco Cenzato, Francesco Curto, Marco Longoni, Cristina Motto, Valentina Oppo, Valentina Perini, Simone Vidale
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xvi, 172 pages) : 38 illus., 6 illus. in color
- Series Title
- Emergency Management in Neurology
- ISBN
- 9783319321301
- 9783319321295 (print ed.)
- ISSN
- 2367-1076
- Subjects (MeSH)
- Clinical Decision-Making
- Emergency Treatment - methods
- Intracranial Hemorrhages - diagnosis
- Intracranial hemorrhages - therapy
- Stroke - diagnosis
- Stroke - therapy
- Abstract
- This book provides detailed practical guidance on the management of hemorrhagic stroke in the clinical settings encountered in daily practice. Real-life cases are used to depict a wide range of clinical scenarios and to highlight significant aspects of management of hemorrhagic stroke. In addition, diagnostic and therapeutic protocols are presented and helpful decision-making algorithms are provided that are specific to the different professionals involved in delivery of stroke care and to differing types of hospital facility. The coverage is completed by the inclusion of up-to-date scientific background information relevant to diagnosis and therapy. Throughout, the approach adopted is both practical and multidisciplinary. The book will be of value for all practitioners involved in the provision of stroke care, and also for medical students.
- Contents
- 1. Diagnosis and therapy in the acute phase of hemorrhagic stroke: latest developments -- 2. Clinical cases -- 3. Clinical organizational pathways for hemorrhagic stroke -- 4. Differentiated decisional algorithms.
- Format
- e-Book
- Location
- Online
How to set up an Acute Stroke Service
https://libcat.nshealth.ca/en/permalink/provcat31123
Iris Q. Grunwald, Klaus Fassbender, Ajay K. Wakhloo.
--Berlin, Heidelberg:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
Stroke is a leading cause of death and disability throughout the world. Intravenous lytics and endovascular stroke treatment were demonstrated to be highly beneficial in clinical trials and in achieving net cost savings. However, time is of the essence in the management of stroke as for every minute that stroke is left untreated, an estimated 1.9 million neurons are destroyed. An optimized stroke pathway can dramatically impact patient outcome. Every medical service will differ. This book offe…
- Available Online
- View e-Book
- Author
- Grunwald, Iris Q
- Other Authors
- Fassbender, Klaus
- Wakhloo, Ajay K
- Responsibility
- Iris Q. Grunwald, Klaus Fassbender, Ajay K. Wakhloo
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xxii, 198 p. : 236 ill., 163 ill. in color)
- ISBN
- 9783642214059
- Subjects (MeSH)
- Critical Care - methods
- Critical Care - organization & administration
- Program Development - methods
- Stroke - therapy
- Subjects (LCSH)
- Critical care medicine
- Neurology
- Abstract
- Stroke is a leading cause of death and disability throughout the world. Intravenous lytics and endovascular stroke treatment were demonstrated to be highly beneficial in clinical trials and in achieving net cost savings. However, time is of the essence in the management of stroke as for every minute that stroke is left untreated, an estimated 1.9 million neurons are destroyed. An optimized stroke pathway can dramatically impact patient outcome. Every medical service will differ. This book offers a concise and practical guide on how to set up and efficiently run an acute stroke service tailored to the needs of the individual center as a provider of primary, secondary, or tertiary care. It documents the essential knowledge on current imaging and treatment options and offers guidance in organizing a site-specific stroke pathway that will ensure the quickest possible provision of treatment, thereby optimizing benefit to the patient and maximizing cost-effectiveness. The authors played an integral part in the development and operation of one of Europe's most successful early stroke centers and also have experience of the factors that can undermine the creation of world-class stroke units. On this basis, they address the key aspects of the stroke pathway and explain how organizing this can reduce the number of severe outcomes by ensuring that appropriate steps are taken during the early moments after stroke when intervention can make a profound difference. The challenging, multidisciplinary nature of care is emphasized, and this handbook will be an invaluable source for every member of the stroke team, including doctors, nurses, stroke coordinators, emergency and rehabilitation providers as well as hospital administrators.
- Contents
- [Machine generated contents note] Pt. I. Understanding Your Goals: The What, Why and Who -- 1. Essential Basics -- 1.1. What Is Stroke? -- 1.2. What Happens During a Stroke? -- 1.3. Why Set Up a Stroke Service? -- 1.4. Understanding the Penumbra Concept -- 1.5. Pathophysiology of Thrombosis -- 1.6. Understanding That "Time Is Brain" -- 1.7. What Is a Stroke Pathway? -- 1.8. Where Should Stroke Care Take Place? -- 1.9. What Is a Stroke Unit? -- 1.10. What Is Decompressive Craniectomy? -- 1.11. What Is Neuroprotection in Stroke? -- References -- Further Reading -- 2. Guidelines and Regulations -- 2.1. Sources of Supporting Information -- 2.2. Guidelines -- Further Reading -- 3. Who Can Support This Project? -- 3.1. Expertise -- 3.2. Funding -- 3.3. Useful Links -- Further Reading -- 4. Basic Milestones in Stroke Treatment -- 4.1. Acute Phase -- 4.2. Post-acute Phase -- 5. Defining Your Priorities -- 6. Walking the Steps and Defining Your Own Pathway and Goals on the Way -- 6.1. Step 1: Pre-hospital Care -- 6.2. Step 2: Patient Evaluation -- 6.3. Step 3: Imaging and Diagnosis -- 6.4. Step 4: Primary Stroke Treatment -- 6.5. Step 5: Advanced Stroke Treatment -- 6.6. Step 6: Post-acute Care/Supporting Treatment -- References -- Further Reading -- 7. Bringing Your Goals into Shape -- 8. Examples of Treatment Pathways -- 8.1. Imaging Pathways -- 9. Specific Pathways in Special Cases -- 9.1. Basilar Artery Thrombosis -- 9.2. Signs of a Major Vessel Occlusion (MCA/ICA) -- 9.3. Portable CT Scanners -- 9.4. DSA with Interventional Treatment as a Primary Choice -- 9.5. Integrated Magnetic Resonance Imaging and X-Ray Angiography -- References -- 10. Future Concepts in Stroke Treatment -- 10.1. MSU: The Concept of a Mobile Stroke Unit -- 10.2. New Strategies for Reduction of the Door-to-Needle Times -- 10.3. Acute Vascular Imaging Concept Using Integrated Imaging -- References -- 11. Strategic/Business Management -- 11.1. Things to Consider in a Budget -- 11.2. Staffing -- 11.3. Who Manages Your Project -- 11.4. Project Management Plan -- Pt. II. Planning -- 12. Establishing Whom and What You Need in the Stroke Pathway -- 12.1. Who Are the Key Parties in a Stroke Service? -- 12.2. Meeting Resistance -- 12.3. Who Are the Key Parties That Need to be Informed? -- 13. Establishing Your Resources (Equipment, Staff, Space) -- 13.1. Determining Non-personnel Resources -- 13.2. Determining Personnel Resources -- 14. Budget and Time Frame -- 14.1. Benefit-Cost Analysis -- Reference -- 15. Risk Assessment and Management -- 16. Team -- 16.1. Setting Up a Project Team -- 16.2. Defining Team Members’ Roles and Responsibilities -- Pt. III. Getting Started -- 17. Work Packages -- 18. Work Groups -- 18.1. Pre-hospital Phase -- 18.2. Acute Phase -- 18.3. Post Treatment Phase -- Pt. IV. Evaluation -- 19. Monitoring -- 19.1. Project Performance -- 19.2. Times and Outcomes -- 20. Marketing -- 20.1. Dissemination -- 20.2. Redefining Your Goals (e.g., Expand Service) -- 21. Closing Remarks.
- Format
- e-Book
- Location
- Online
Hypothermia and cerebral ischemia : mechanisms and clinical applications
https://libcat.nshealth.ca/en/permalink/provcat21538
Maier, Carolina M.
--Totowa, NJ:
Humana Press
, 2004.
- Call Number
- WL 355 M217h 2004
- Location
- Halifax Infirmary
- Call Number
- WL 355 M217h 2004
- Author
- Maier, Carolina M
- Other Authors
- Steinberg, Gary K
- Place of Publication
- Totowa, NJ
- Publisher
- Humana Press
- Date of Publication
- 2004
- Physical Description
- 188 p.
- ISBN
- 089603660X
- Subjects (MeSH)
- Hypothermia, Induced
- Brain ischemia - therapy
- Brain Injuries - therapy
- Stroke - therapy
- Format
- Book
- Location
- Halifax Infirmary
- Loan Period
- 3 weeks
Immunological mechanisms and therapies in brain injuries and stroke
https://libcat.nshealth.ca/en/permalink/provcat33765
Jun Chen, Xiaoming Hu, Mary Stenzel-Poore, John H. Zhang, editors.
--New York:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Recent research has revealed the importance of immunological mechanisms and inflammation in delaying damage and/or promoting repair after an acute injury to the central nervous system. This book provides a comprehensive and up-to-date overview of the role of immunological mechanisms and therapies for treating acute neurological injuries such as cerebral ischemia, hemorrhage, and brain and spinal cord trauma. In several sections, the contributing authors provide a review of immunological mechani…
- Available Online
- View e-Book
- Other Authors
- Chen, Jun
- Responsibility
- Jun Chen, Xiaoming Hu, Mary Stenzel-Poore, John H. Zhang, editors
- Place of Publication
- New York
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (x, 386 pages)
- Series Vol.
- v. 6
- Series Title
- Springer series in translational stroke research
- ISBN
- 9781461489153 (electronic bk.)
- 9781461489146
- Subjects (MeSH)
- Central Nervous System - immunology
- Central Nervous System - injuries
- Stroke - immunology
- Stroke - therapy
- Subjects (LCSH)
- Brain - Wounds and injuries - Treatment
- Cerebrovascular disease - Treatment
- Stroke - immunology
- Stroke - therapy
- Brain Injuries - immunology
- Brain Injuries - therapy
- Biomedicine
- Neurosciences
- Neurology
- Abstract
- Recent research has revealed the importance of immunological mechanisms and inflammation in delaying damage and/or promoting repair after an acute injury to the central nervous system. This book provides a comprehensive and up-to-date overview of the role of immunological mechanisms and therapies for treating acute neurological injuries such as cerebral ischemia, hemorrhage, and brain and spinal cord trauma. In several sections, the contributing authors provide a review of immunological mechanisms involved in neurological injury and of various translational and clinical research aimed at harnessing those mechanisms for better patient outcomes.
- Contents
- 1. Old Dogmas, Surprising Complexities, and Novel Therapeutic Targets -- 2. The Critical Roles of Immune Cells in Acute Brain Injuries -- 3. Vascular Inflammation in Ischemic Stroke: Adhesion Receptors Controlling Leukocyte–Endothelial Interactions -- 4. Immune Cell-Derived Free Radicals in Acute Brain Injury -- 5. The Complement Cascade in Acute Brain Injury -- 6. Matrix Metalloproteinases as an Inflammatory Mediator in the Neurovascular Unit -- 7. Toll-Like Receptors in Ischemic Stroke and Other Acute Brain Injuries -- 8. Ion Transporters in Microglial Function: New Therapeutic Targets for Neuroinfl ammation in Ischemic Stroke? -- 9. Inflammation After Acute Brain Injuries Affects the Developing Brain Differently than the Adult Brain -- 10. Systemic Immune Responses after Experimental Stroke -- 11. Infectious Burden and Risk of Stroke -- 12. Inflammatory Biomarkers in Patients with Acute Brain Injuries -- 13. In Vivo Imaging of Neuroinflammation in Acute Brain Injury -- 14. Inflammation as a Therapeutic Target after Subarachnoid Hemorrhage: Advances and Challenges -- 15. Minocycline, A Tetracycline Derivative, as a Potential Protective Agent for Acute Stroke -- 16. Tolerization to Brain and Vascular Antigens: Targeting Autoimmunity After Acute Brain Injuries and Preventing Stroke -- 17. The Role of PPAR in Stroke -- 18. CD36: An Inflammatory Mediator in Acute Brain Injury -- 19. Cool Down the Inflammation: Hypothermia as a Therapeutic Strategy for Acute Brain Injuries.
- Format
- e-Book
- Location
- Online
Ischemic Stroke
https://libcat.nshealth.ca/en/permalink/provcat41308
Giuseppe D’Aliberti, Marco Longoni, Cristina Motto, Valentina Oppo, Valentina Perini, Luca Valvassori, Simone Vidale.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book provides detailed practical guidance on the management of acute ischemic stroke in the clinical settings encountered in daily practice. Real-life cases are used to depict a wide range of clinical scenarios and to highlight significant aspects of management of ischemic stroke. In addition, diagnostic and therapeutic protocols are presented and helpful decision-making algorithms are provided that are specific to the different professionals involved in delivery of acute stroke care and t…
- Available Online
- View e-Book
- Author
- D’Aliberti, Giuseppe
- Other Authors
- Longoni, Marco
- Motto, Cristina
- Oppo, Valentina
- Perini, Valentina
- Valvassori, Luca
- Vidale, Simone
- Responsibility
- Giuseppe D’Aliberti, Marco Longoni, Cristina Motto, Valentina Oppo, Valentina Perini, Luca Valvassori, Simone Vidale
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xiii, 91 pages) : 25 illus., 9 illus. in color
- Series Title
- Emergency Management in Neurology
- ISBN
- 9783319317052
- 9783319317045 (print ed.)
- ISSN
- 2367-1076
- Subjects (MeSH)
- Brain ischemia - diagnosis
- Brain ischemia - therapy
- Clinical Decision-Making
- Emergency Treatment - methods
- Stroke - diagnosis
- Stroke - therapy
- Abstract
- This book provides detailed practical guidance on the management of acute ischemic stroke in the clinical settings encountered in daily practice. Real-life cases are used to depict a wide range of clinical scenarios and to highlight significant aspects of management of ischemic stroke. In addition, diagnostic and therapeutic protocols are presented and helpful decision-making algorithms are provided that are specific to the different professionals involved in delivery of acute stroke care and to differing types of hospital facility. The coverage is completed by the inclusion of up-to-date scientific background information relevant to diagnosis and therapy. Throughout, the approach adopted is both practical and multidisciplinary. The book will be of value for all practitioners involved in the provision of acute stroke care, and also for medical students.
- Contents
- Brief Description of Recent Developments in Diagnosis and Treatment -- Clinical Cases -- Organizational Clinical Pathways -- Differentiated Decisional Algorithms.
- Format
- e-Book
- Location
- Online
Ischemic Stroke Therapeutics : A Comprehensive Guide
https://libcat.nshealth.ca/en/permalink/provcat39783
Bruce Ovbiagele, editor.
(1st ed.)
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This complete resource captures state-of-the-art strategies and the accelerated pace of discovery that is revolutionizing what is known about ischemic stroke and its treatment. Therapeutics for acute management, secondary prevention, recovery, rehabilitation, asymptomatic cerebral ischemia, and implementation of stroke systems of care are all discussed in this comprehensive yet practical guide. Chapters are authored by leading academicians with extensive clinical practice experience from all ov…
- Available Online
- View e-Book
- Other Authors
- Ovbiagele, Bruce
- Responsibility
- Bruce Ovbiagele, editor
- Edition
- 1st ed.
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xiii, 322 p. : 89 illus., 49 illus. in color)
- ISBN
- 9783319177502
- 9783319177496 (print ed.)
- Subjects (MeSH)
- Brain ischemia - therapy
- Secondary Prevention - methods
- Stroke - therapy
- Abstract
- This complete resource captures state-of-the-art strategies and the accelerated pace of discovery that is revolutionizing what is known about ischemic stroke and its treatment. Therapeutics for acute management, secondary prevention, recovery, rehabilitation, asymptomatic cerebral ischemia, and implementation of stroke systems of care are all discussed in this comprehensive yet practical guide. Chapters are authored by leading academicians with extensive clinical practice experience from all over the world and feature the scientific evidence behind prevailing therapeutic strategies for managing ischemic cerebrovascular disease. The specialist or general practitioner will gain critical knowledge in stroke management, current clinical challenges and promising new therapies under investigation.
- Contents
- 1. General Concepts: Management of Acute Ischemic Stroke -- 2. Pre-hospital Stroke Treatment (EMS stabilization protocols) -- 3. Intravenous Thrombolysis and Anti-thrombotics -- 4. Intra-Arterial Therapy for Acute Ischemic Stroke -- 5. Hemicraniectomy -- 6. Supportive Care and Management of In-hospital Complications -- 7. Post-Discharge Complications of Stroke -- 8. General Concepts: Stroke Mechanisms, Subtyping, and Work Up -- 9. Traditional Stroke Risk Factor Treatment -- 10. Heterogeneous causes of stroke: Antithrombotics -- 11. Heterogeneous Causes of Stroke: Select Emerging Risk Factors -- 12. Secondary Prevention After Cardioembolic Stroke -- 13. Secondary Prevention after Ischemic Lacunar Stroke -- 14. Secondary Prevention after Symptomatic Large Artery Extracranial Disease -- 15. Secondary Prevention after Symptomatic Large Artery Intracranial Disease -- 16. Secondary Prevention after Non-atherosclerotic Cerebral Vasculopathies -- 17. Secondary Prevention after Ischemic Strokes due to Hypercoagulable States -- 18. General Concepts: Therapies for Rehabilitation and Recovery -- 19. Botulinum Toxin for Post-Stroke Limb Spasticity -- 20. Selective Serotonin Re-uptake Inhibitors -- 21. Constraint Induced Therapies -- 22. Virtual Reality in Stroke Rehabilitation -- 23. Transcranial Magnetic Stimulation -- 24. General Concepts: Management of Asymptomatic Cerebrovascular Disease -- 25. Asymptomatic Carotid Artery Stenosis -- 26. Subclinical Vascular Brain Injury -- 27. General Concepts: Stroke Systems of Care -- 28. Stroke Centers and Related Aspects of Stroke Systems -- 29. Role of Registries and Community Models in Developed Countries -- 30. Telemedicine in Stroke Systems of Care.
- Format
- e-Book
- Location
- Online
Management of Post-Stroke Complications
https://libcat.nshealth.ca/en/permalink/provcat39297
Ajay Bhalla, Jonathan Birns, editors.
--Cham:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
This book highlights the underlying importance of post-stroke complications during recovery, allowing healthcare professionals managing stroke patients to understand their frequency and identify which patients are at risk of developing such complications. Complications are categorised into neurological and non-neurological, and the time-frame for these complications both in the short-term and long-term are discussed. The common practices in managing post-stroke complications and the skills requ…
- Available Online
- View e-Book
- Other Authors
- Bhalla, Ajay
- Birns, Jonathan
- Responsibility
- Ajay Bhalla, Jonathan Birns, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (x, 390 p. : 30 illus., 18 illus. in color)
- ISBN
- 9783319178554
- 9783319178547 (print ed.)
- Subjects (MeSH)
- Stroke - complications
- Stroke - therapy
- Abstract
- This book highlights the underlying importance of post-stroke complications during recovery, allowing healthcare professionals managing stroke patients to understand their frequency and identify which patients are at risk of developing such complications. Complications are categorised into neurological and non-neurological, and the time-frame for these complications both in the short-term and long-term are discussed. The common practices in managing post-stroke complications and the skills required in their prevention are described, as is the evidence base from clinical trials around their management. The book concludes with a discussion of new developments and research priorities for the future. Management of Post-Stroke Complications is aimed at members of the multidisciplinary stroke team, stroke physicians, neurologists, general practitioners, stroke specialists in training, and medical students.
- Contents
- 1. Introduction -- 2. Early Neurological Deterioration -- 3. Post-Stroke Cardiac Complications -- 4. Post-Stroke Seizures -- 5. Infections After Stroke -- 6. Venous Thromboembolism -- 7. Swallowing and Nutritional Complications -- 8. Urinary and Bowel Complications -- 9. Positioning and Pressure Care -- 10. Management of Spasticity -- 11. Falls and Osteoporosis Post-Stroke -- 12. Post-Stroke Cognitive Impairment -- 13. Post-Stroke Pain -- 14. Post-Stroke Fatigue: Common But Poorly Understood -- 15. Mental Consequences Of Stroke -- 16. Future Developments.
- Format
- e-Book
- Location
- Online
Neuroprotective Therapy for Stroke and Ischemic Disease
https://libcat.nshealth.ca/en/permalink/provcat41539
Paul A. Lapchak, John H. Zhang, editors.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book is a critical and comprehensive look at current state-of-the-art scientific and translational research being conducted internationally, in both academia and industry; it serves to address new ways to provide effective treatment to victims of ischemic and hemorrhagic stroke and other ischemic diseases. Currently, stroke can be successfully treated through the administration of a thrombolytic, but the therapeutic window is short and many patients are not able to receive treatment. Only …
- Available Online
- View e-Book
- Other Authors
- Lapchak, Paul A.
- Zhang, John H.
- Responsibility
- Paul A. Lapchak, John H. Zhang, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xvii, 795 pages) : 105 illus., 71 illus. in color
- Series Title
- Springer series in translational stroke research
- ISBN
- 9783319453453
- 9783319453446 (print ed.)
- ISSN
- 2363-958X
- Abstract
- This book is a critical and comprehensive look at current state-of-the-art scientific and translational research being conducted internationally, in both academia and industry; it serves to address new ways to provide effective treatment to victims of ischemic and hemorrhagic stroke and other ischemic diseases. Currently, stroke can be successfully treated through the administration of a thrombolytic, but the therapeutic window is short and many patients are not able to receive treatment. Only about 30% of patients are "cured" by available treatments. Divided into five sections, the proposed volume explores historical and novel neuroprotection mechanisms and targets, new and combination therapies, as well as clinical trial design for some of the most recent bench-side research.
- Contents
- Reflections on Neuroprotection Research and the Path Toward Clinical Success -- Systematic review & meta-analysis: important tools in understanding -- Neuroprotection is Technology, not Science -- History of Experimental Stroke Research -- History of Neuroprotection: Trials and Tribulations -- Targeting PSD-95 As a Novel Approach in the Treatment of Stroke -- ATP Sensitive Potassium Channels (KATP) Play a Role in Hypoxic Preconditioning against Neonatal Hypoxic-Ischemic Brain Injury -- Targeting Oxidative Stress in Stroke -- Nitrones, Old Fellows for New Therapies in Ischemic Stroke -- Neuroprotective strategies via modulation of innate immune receptors -- Harnessing the power of the human immune system via multi-omic immune profiling in stroke treatment and recovery -- Polarization of microglia/macrophages in brain ischemia: relevance for stroke therapy -- Endoplasmic Reticulum Stress: An Opportunity for Neuroprotective Strategies after Stroke -- Effects of Neuroprotectants before and after stroke: Statins and Anti-Hypertensives -- Toward Effective Combination Therapy and Pleiotropic Drugs -- TRPM7 Channels as Potential Therapeutic Targets for Stroke Cholinergic Protection in Ischemic Brain Injury -- Remote Ischemic Conditioning: A Highly Translatable Therapy for Acute Stroke -- Hypothermia for Acute Ischemic Stroke -- Modern endovascular treatment of ischemic disease -- Cerebral Microbleeds and Thrombolysis for Acute Ischemic Stroke -- Targeting pericytes and the microcirculation for ischemic stroke therapy -- Thrombolytic and Endovascular Therapies for Acute Ischemic Stroke -- Sonothrombolysis for acute ischemic stroke: a critical appraisal -- Combination Therapy with Thrombolysis -- Oxygen Carriers: Are they enough for cellular support? -- A new paradigm in protecting ischemic brain: preserving the neurovascular unit before reperfusion -- The right rodent for the job: infarct variability between strains and its impact on logistics of experimental animal studies -- Rabbit Spinal Cord Ischemia Model for the Development of Neuroprotective Treatments -- Stroke Sex Differences: from basic research to clinical trials -- Unpuzzling the co-morbid type 2 diabetes and hypertension-related cognitive dysfunction and stroke -- Sex Specific Factors in Stroke -- Current Imaging Strategies for Patient Selection in Acute Ischemic Stroke Trials.
- Format
- e-Book
- Location
- Online
Non-Neuronal Mechanisms of Brain Damage and Repair After Stroke
https://libcat.nshealth.ca/en/permalink/provcat40218
Jun Chen, John H. Zhang, Xiaoming Hu, editors.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book provides a comprehensive overview of the latest research in the role of non-neuronal cells - astrocytes, oligodendrocytes, endothelial cells, pericytes, microglia, and other immune cells in ischemic brain injury and long-term recovery. In these cases, neurodegeneration and brain repair are controlled in a sophisticated system, incorporating interactions between different cell types and cellular systems. Also explored are the therapeutic strategies that target non-neuronal responses af…
- Available Online
- View e-Book
- Other Authors
- Chen, Jun
- Zhang, John H
- Hu, Xiaoming
- Responsibility
- Jun Chen, John H. Zhang, Xiaoming Hu, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xiii, 408 p. : 49 illus., 44 illus. in color)
- Series Title
- Springer series in translational stroke research
- ISBN
- 9783319323374
- 9783319323350 (print ed.)
- ISSN
- 2363-958X
- Subjects (MeSH)
- Neovascularization, physiologic
- Neuroglia
- Stroke - immunology
- Stroke - therapy
- White Matter
- Abstract
- This book provides a comprehensive overview of the latest research in the role of non-neuronal cells - astrocytes, oligodendrocytes, endothelial cells, pericytes, microglia, and other immune cells in ischemic brain injury and long-term recovery. In these cases, neurodegeneration and brain repair are controlled in a sophisticated system, incorporating interactions between different cell types and cellular systems. Also explored are the therapeutic strategies that target non-neuronal responses after stroke and their translational potentials.
- Contents
- Part I. Microvascular integrity in stroke -- Structural alterations to the endothelial tight junction complex during stroke -- Role of pericytes in neurovascular unite and stroke -- Glial support of blood-brain barrier integrity: Molecular targets for novel therapeutic strategies in stroke -- Barrier mechanism in neonatal stroke -- Angiogenesis: a realistic therapy for ischemic stroke -- Part II. Glial cells in stroke -- Astrocytes as a target for ischemic stroke -- Microglia: a double-sided sword in stroke -- Crosstalk between cerebral endothelium and oligodendrocyte after stroke -- Part III. Peripheral immune cells in stroke -- The peripheral immune response to stroke -- The role of spleen-derived immune cells in ischemic brain injury -- Regulatory T cells in ischemic brain injury -- B cells in stroke and preconditioning-induced protection against stroke -- Mast cell as an early responder in ischemic brain injury -- Roles of neutrophils in stroke -- The function of cytokines in ischemic stroke -- Part IV. White matter injury and repair in stroke -- Ischemic injury to white matter: an age-dependent process -- Part V. Emerging Therapies to Target Non- neuronal Mechanisms After Stroke -- Neurovascular repair after stroke -- The role of non-neuronal Nrf2 pathway in ischemic stroke: damage control and potential tissue repair -- Stem cell therapy for ischemic stroke.
- Format
- e-Book
- Location
- Online
Posterior Circulation Stroke : Advances in Understanding and Management
https://libcat.nshealth.ca/en/permalink/provcat46351
Jong S. Kim, editor.
--Singapore:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Location
- Online
This book, written by renowned experts from across the world, provides readers with a detailed and up-to-date understanding of posterior circulation stroke and its management. Anatomy, pathophysiology, clinical syndromes, and imaging findings are clearly and thoroughly described with the aid of illustrative cases and schematic drawings. The management-oriented chapters explain all forms of treatment, including the use of antiplatelet agents and anticoagulants, thrombolysis, mechanical thrombect…
- Available Online
- View e-Book
- Other Authors
- Kim, Jong S.
- Responsibility
- Jong S. Kim, editor
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (viii, 238 p.) : 92 illus., 46 illus. in color
- ISBN
- 9789811567391
- 9789811567384 (Print ed.)
- 9789811567407 (Print ed.)
- 9789811567414 (Print ed.)
- Subjects (MeSH)
- Infarction, Posterior Cerebral Artery
- Stroke - therapy
- Specialty
- Cardiology
- Neurology
- Abstract
- This book, written by renowned experts from across the world, provides readers with a detailed and up-to-date understanding of posterior circulation stroke and its management. Anatomy, pathophysiology, clinical syndromes, and imaging findings are clearly and thoroughly described with the aid of illustrative cases and schematic drawings. The management-oriented chapters explain all forms of treatment, including the use of antiplatelet agents and anticoagulants, thrombolysis, mechanical thrombectomy, stenting, and surgical therapy, i.e., bypass and decompression. Throughout, full account is taken of recent significant advances in knowledge and clinical practice. Stroke affecting the posterior circulation continues to pose particular challenges for clinicians. This book will help readers to avoid misdiagnosis, which still occurs far too frequently, and to manage individual patients optimally. It will be an excellent learning resource for residents in neurology, neurosurgery, radiology, interventional radiology, and vascular surgery, as well as an ideal reference for more experienced practitioners in these specialties.
- Contents
- 1. History of Vertebrobasilar Territory Stroke and TIA -- 2. Arterial Anatomy and Collaterals -- 3. Epidemiology, Risk Factors, and Stroke Mechanisms -- 4. Brain Stem Infarction Syndromes -- 5. Thalamic and Other Posterior Cerebral Artery Stroke Syndromes -- 6. Cerebellar Infarction -- 7. Ocular, Vestibular, and Otologic Syndromes -- 8. Hemorrhagic Strokes -- 9. Imaging Diagnosis -- 10. Medical Treatment -- 11. Thrombolysis and Thrombectomy -- 12. Angioplasty and Stenting for Posterior Circulation Stroke -- 13. Surgical Therapy -- 14. Non-atherosclerotic, Uncommon Diseases -- 15. Outcomes and Prognosis.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Prevention and treatment of ischemic stroke
https://libcat.nshealth.ca/en/permalink/provcat21655
Kasner, Scott E.
--Philadelphia, PA:
Butterworth-Heinemann
, 2004.
- Call Number
- WL 355 P944 2004
- Location
- Dickson Building
- Halifax Infirmary
- Call Number
- WL 355 P944 2004
- Author
- Kasner, Scott E
- Other Authors
- Gorelick, Philip B
- Place of Publication
- Philadelphia, PA
- Publisher
- Butterworth-Heinemann
- Date of Publication
- 2004
- Physical Description
- 416 p.
- Series Vol.
- 29
- Series Title
- Blue books of practical neurology
- ISBN
- 0750674644
- Format
- Book
- Location
- Dickson Building
- Halifax Infirmary
- Copies
- 2
- Loan Period
- 3 weeks
Caplan, Louis R.
--Oxford, England:
Oxford University Press
, 2011.
- Call Number
- WL 355 S921 2011
- Holdings
- Cape Breton Regional: 2011.
- Location
- Halifax Infirmary
- Call Number
- WL 355 S921 2011
- Author
- Caplan, Louis R
- Place of Publication
- Oxford, England
- Publisher
- Oxford University Press
- Date of Publication
- 2011
- Holdings
- Cape Breton Regional: 2011.
- Physical Description
- 173 p.
- Series Title
- What do I do now?
- ISBN
- 9780199739141
- ISSN
- 0039-2499
- Subjects (MeSH)
- Stroke - diagnosis - case reports
- Stroke - therapy - case reports
- Format
- Book
- Location
- Halifax Infirmary
- Loan Period
- 3 weeks
Stroke Prevention in Clinical Practice
https://libcat.nshealth.ca/en/permalink/provcat40641
Daryll M. Baker.
--London:
Springer
, c2008.
- Available Online
- View e-Book
- Location
- Online
Comprised of short chapters written in a succinct and bulleted style, with clear diagrams and figures to illustrate where appropriate, Stroke Prevention in Clinical Practice is ideal for the busy doctor looking for a comprehensive pocket-sized guide to the everyday management of transient ischaemic attacks (TIAs) and strokes. Strokes are the major cause of disability in the UK, and also the third biggest killer, but awareness and active intervention can prevent the dangers of strokes especially…
- Available Online
- View e-Book
- Author
- Baker, Daryll M
- Responsibility
- Daryll M. Baker
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2008
- Physical Description
- 1 online resource (viii, 131 p. : 30 illus.)
- ISBN
- 9781846287282
- 9781852339647 (print ed.)
- Subjects (MeSH)
- Myocardial Ischemia - prevention & control
- Risk Factors
- Stroke - diagnosis
- Stroke - prevention & control
- Stroke - therapy
- Abstract
- Comprised of short chapters written in a succinct and bulleted style, with clear diagrams and figures to illustrate where appropriate, Stroke Prevention in Clinical Practice is ideal for the busy doctor looking for a comprehensive pocket-sized guide to the everyday management of transient ischaemic attacks (TIAs) and strokes. Strokes are the major cause of disability in the UK, and also the third biggest killer, but awareness and active intervention can prevent the dangers of strokes especially in high-risk groups. By starting with an explanation of TIAs, which so often preceed strokes, this work aims to make more physicians aware of the treatment regimens necessary to manage TIAs. It is vital to be aware of the early signs of TIAs, and be able to recognise them as soon as possible since a considerable amount of stroke prevention treatment stems from knowing the warning signs and taking action. This book discusses how to accurately diagnose the leading causes of strokes, and offers comprehensive treatment advice to avoid future recurrences, with all chapters written by leading experts in the field.
- Contents
- I. Introduction -- The Significance Of Stroke -- Identifying Patients at Risk of Ischemic Stroke -- Investigating Patients at Risk of Stroke -- II. Reducing the Risk of Stroke by Reducing Embolic Events -- Antiplatelet Therapy -- Reducing Cardioembolic Events -- Reducing Cervical Vessel Embolic Events -- III. Reducing the Risk of Stroke by Modifying Atherosclerotic Risk Factors -- Managing Hypertension -- Managing Diabetes -- Managing Hyperlipidemia -- Reducing the Risk of Stroke by Modifying Life Style -- Identifying Other Atherosclerotic Diseases -- Managing Lacunar Infarcts -- Part IV. Reducing the Risk of Stroke by Reducing Procoagulant (Thrombotic) Risk Factors -- Managing Procoagulant Thrombotic States -- V. Reducing the Risk of Stroke from Other Causes -- Managing Central Nervous System Vasculitis -- Managing Stroke in Human Immunodeficiency Virus-Infected Patients -- Thyroid Diseases and Stroke -- VI. Prevention of Other Cardiovascular Events in Cerebrovascular Patients -- Management of Silent Myocardial Ischemia in Stroke Patients.
- Format
- e-Book
- Publication Type
- Handbook
- Location
- Online
Stroke Recovery with Cellular Therapies
https://libcat.nshealth.ca/en/permalink/provcat29602
edited by Sean I. Savitz, Daniel M. Rosenbaum.
--Totowa, NJ:
Humana Press
, c2008.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Savitz, Sean I
- Other Authors
- Rosenbaum, Daniel M
- Responsibility
- edited by Sean I. Savitz, Daniel M. Rosenbaum
- Place of Publication
- Totowa, NJ
- Publisher
- Humana Press
- Date of Publication
- c2008
- Series Title
- Current clinical neurology
- ISBN
- 9781603270571
- Subjects (MeSH)
- Brain ischemia - therapy
- Intracranial hemorrhages - therapy
- Stem cell transplantation - ethics
- Stem cell transplantation - methods
- Stroke - therapy
- Subjects (LCSH)
- Neurology
- Transplantation of organs tissues etc
- Format
- e-Book
- Location
- Online
Stroke Revisited : Diagnosis and Treatment of Ischemic Stroke
https://libcat.nshealth.ca/en/permalink/provcat41945
Seung-Hoon Lee, editor.
--Singapore:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book presents state of the art knowledge on stroke management in a unique organizational style. Ischemic stroke is extensively covered, with inclusion of overviews that dynamically describe all relevant diagnostic and therapeutic processes in a time sequence mirroring real practice. The individual components of management and key issues are fully discussed with the aid of complementary illustrations that facilitate understanding of practical aspects and enable the reader to retrieve fundam…
- Available Online
- View e-Book
- Other Authors
- Lee, Seung-Hoon
- Responsibility
- Seung-Hoon Lee, editor
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xix, 379 pages) : 94 illus., 76 illus. in color
- Series Title
- Stroke revisited
- ISBN
- 9789811014246
- 9789811014239 (print ed.)
- Subjects (MeSH)
- Brain ischemia - diagnosis
- Brain ischemia - therapy
- Stroke - diagnosis
- Stroke - therapy
- Abstract
- This book presents state of the art knowledge on stroke management in a unique organizational style. Ischemic stroke is extensively covered, with inclusion of overviews that dynamically describe all relevant diagnostic and therapeutic processes in a time sequence mirroring real practice. The individual components of management and key issues are fully discussed with the aid of complementary illustrations that facilitate understanding of practical aspects and enable the reader to retrieve fundamental information quickly. In addition, the book considers the various causes of stroke and provides detailed guidance on means of secondary prevention. The recent demonstration of the substantial benefit of intra-arterial thrombectomy using stentrievers in patients with acute ischemic stroke represents a great moment in the history of stroke management. As we embark on a new era, there is an urgent need to review and evaluate current modalities for stroke diagnosis and treatment. In tackling this task, this book will be invaluable for physicians, angiographic interventionists, surgeons, and students seeking to acquire up-to-date knowledge on stroke.
- Contents
- Part I. Initial Assessment of Patients with Stroke-Like Symptoms -- 1. Stroke Center -- 2. Stroke Unit -- 3. Initial Assessment and Differential Diagnosis -- Part II. Diagnosis and Treatment of Stroke: Acute Stage -- 4. Overview of Patient Management Flow -- 5. Initial Diagnosis and Management of Acute Ischemic Stroke -- 6. Intravenous Thrombolysis for Acute Ischemic Stroke -- 7. History of Intra-arterial Thrombolysis -- 8. Mechanical Thrombectomy: New Era of Stent Retriever -- 9. Principles and Practical Application of Brain CT in Acute Ischemic Stroke -- 10. Principles and Practical Application of Brain MRI in Acute Ischemic Stroke -- 11. Identification of Stroke Mechanism: Stroke Classification -- 12. Selections of Antithrombotic Agents During Acute Stage -- 13. Ischaemic Stroke: Indication and Techniques of Decompressive Surgery -- 14. Critical and Medical Management in Acute Stage of Ischemic Stroke -- 15. Rehabilitation in Acute Stage -- Part III. Certain but Relatively Frequent Causes of Ischemic Stroke -- 16. Cerebral Venous Sinus Thrombosis -- 17. Stroke Caused by Cervical Artery Dissection -- 18. Antiphospholipid Antibody Syndrome -- 19. Cancer-Related Stroke -- 20. Moyamoya Disease -- 21. Central Nervous System Vasculitis -- 22. Genetic Causes of Ischemic Stroke -- Part IV. Secondary Prevention of Stroke -- 23. Identification of Vascular Risk Factors -- 24. Hypertension Management in Acute Ischemic Stroke -- 25. Diabetes Management After Stroke -- 26. Cholesterol Management After Stroke -- 27. Understanding Paradox of Risk Factors -- 28. Antithrombotics: Antiplatelet Drugs -- 29. Antithrombotics: Anticoagulants Including NOACs -- 30. Carotid Endarterectomy Versus Carotid Angioplasty and Stenting for Stroke Prevention -- 31. Post-Stroke Management: Emotional Disturbances and Pain -- 32. Identification of Vascular Cognitive Impairment -- 33. Rehabilitation in Subacute and Chronic Stage After Stroke -- Part V. Clinical Practice Guidelines -- 34. History, Purpose, and Use of Clinical Practice Guidelines for Stroke -- 35. Discrepancy and Pitfalls of Clinical Practice Guideline.
- Format
- e-Book
- Location
- Online
