Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lu…
This book covers all clinical aspects of acute respiratory distress syndrome (ARDS), from definition to treatment, focusing on the more recent recommendations and evidence-based medicine. The addressed topics are the various ventilation strategies, the impact of prone positioning, the use of partial and total extracorporeal support, the value of vasodilators, the weaning from mechanical ventilation, the pharmacological interventions, noninvasive ventilation, and the strategies using anti-inflam…
This book critically examines the many complex entanglements between AIDS activism and HIV science. It takes readers on a medical anthropological expedition across time and space that highlights the stakes from the perspective of those most affected by the epidemic. Author Robert Lorway reveals how early in the HIV epidemic, amid inadequate government leadership, communities of people living with and directly affected by HIV and AIDS rose to become a vital force at the forefront of prevention r…
This book is the first full-length study of HIV/AIDS work in relation to government and NGOs. In the early 2000s, Pakistan's response to HIV/AIDS was scaled-up and declared an area of urgent intervention. This response was funded by international donors requiring prevention, care and support services to be contracted out to NGOs: a global policy considered particularly important in Pakistan where the high risk populations are criminalized by the state. Based on unparalleled ethnographic access …
This ambitious book provides a comprehensive history of the World Health Organization (WHO) Global Programme on AIDS (GPA), using it as a unique lens to trace the global response to the AIDS pandemic. The authors describe how WHO came initially to assume leadership of the global response, relate the strategies and approaches WHO employed over the years, and expound on the factors that led to the Programme's demise and subsequent formation of the Joint United Nations Programme on HIV/AIDS (UNAID…
This text provides a concise yet comprehensive overview of Alagille syndrome. The book reviews the pathophysiology and genetics of the disorder, discusses recent molecular advances and its impact on diagnostics, and describes management challenges and strategies. The text also touches upon future treatment options. Written by experts in the field, Alagille Syndrome: Pathogenesis and Clinical Management is a valuable resource for physicians and researchers dealing with this disorder, one that wi…
The book provides the first state-of-the-art overview of Alice in Wonderland syndrome, an enigmatic neurological condition characterized by a range of perceptual distortions (for example, seeing things as being larger or smaller than they actually are; seeing human faces change into animal faces; feeling one’s body growing larger or smaller; experiencing time as slowing down or speeding up, etc.). It describes the clinical presentation of the syndrome, including its huge variety of symptoms and…
This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss or complications are explained. The main clinical manifestations and classification criteria are described and diagnostic tools, identified. Close attention is …
This new edition is a comprehensive and updated resource on antiphospholipid syndrome (APS), which is an autoimmune disorder. In APS, the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies (antiphospholipid antibodies) against them. APS is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis, and pulmonary thromboembolism. It is also associated wi…
The International Congress on Antiphospholipid Antibodies is held every three years to discuss the recent advances and future directions in Antiphospholipid Syndrome (APS). This volume collects the scientific highlights and new findings about APS that were generated from the most recent 13th Congress, held in Galveston, Texas in 2010. Chapters were written by an internationally-distinguished group of scientists from the point-of-view of multiple specialty areas. Each chapter was written in a un…
This book explores a number of issues related to the stigma arising from HIV/AIDS infection, perceived or actual discrimination from the community and society, and the extent of vulnerabilities for infected Asian refugees and immigrants. It assesses the health care and treatment regimen for HIV/AIDS accessed by immigrants and refugee claimants in North America, including treatments offered by the health-care system and ethnic communities, and their perceptions and biases relating to HIV/AIDS is…