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Atlas of Thyroid and Neuroendocrine Tumor Markers

https://libcat.nshealth.ca/en/permalink/provcat43325
Luca Giovanella, editor. --Cham: Springer , c2018.
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This book highlights the increase in thyroid tumors and NET and demonstrates the growing importance of circulating markers in diagnosis as well as treatment and follow-up. Dramatic technical improvements have heightened the clinical impact of well-established, conventional biochemical markers. In addition, more recent genetic and molecular approaches have provided innovative molecular markers. In this context, effective communication between clinicians and laboratory physicians/scientists is es…
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Other Authors
Giovanella, Luca
Responsibility
Luca Giovanella, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xii, 249 p.) : 41 illus., 30 illus. in color
ISBN
9783319625065
9783319625058 (print ed.)
9783319625072 (print ed.)
9783319873305 (print ed.)
Subjects (MeSH)
Biomarkers, Tumor
Neuroendocrine Tumors - diagnosis
Neuroendocrine Tumors - therapy
Thyroid Neoplasms - diagnosis
Thyroid Neoplasms - therapy
Specialty
Endocrinology
Medical Oncology
Abstract
This book highlights the increase in thyroid tumors and NET and demonstrates the growing importance of circulating markers in diagnosis as well as treatment and follow-up. Dramatic technical improvements have heightened the clinical impact of well-established, conventional biochemical markers. In addition, more recent genetic and molecular approaches have provided innovative molecular markers. In this context, effective communication between clinicians and laboratory physicians/scientists is essential in allowing all those involved to fully profit from these exciting advances. In this comprehensive, up-to-date book, authors from different laboratory and clinical areas link laboratory and clinical topics. Analytical problems such as interferences, false-negative and false-positive results are discussed in depth, and flow-charts offer insights into identifying and avoiding them. Illustrated clinical cases detail the clinical role and limitations of different tumor markers. Lastly, it explores health technology assessment and economic issues. This is a valuable resource for endocrinologists, oncologists, nuclear medicine physicians, scientists and technologists who want to keep abreast of the latest developments.
Contents
Part I. Pathology and Pathobiology -- 1. Pathology and Immunohistochemistry in Thyroid Tumors -- 2. Pathology of Neuroendocrine Neoplasms: Morphological, Immunophenotypical, and Circulating Molecular Markers -- 3. Circulating Biomarkers: Biological Basis, Methods, and Interpretation Criteria -- Part II. Differentiated Thyroid Cancer -- 4. Differentiated Thyroid Cancer: Diagnosis, Therapy, and Follow-Up -- 5. Thyroglobulin and Thyroglobulin Antibodies -- 6. Circulating Molecular Biomarkers in Thyroid Cancer -- 7. Circulating Epithelial Tumor Cells in Thyroid Carcinoma -- Part III. Medullary Thyroid Carcinoma -- 8. Medullary Thyroid Carcinoma (MTC): Diagnosis, Treatment and Follow-Up -- 9. Calcitonin and Carcinoembryonic Antigen for the Diagnosis and Management of Medullary Thyroid Carcinoma -- 10. Procalcitonin: Are We Ready for Clinical Use? -- Part IV. Aggressive and Rare Thyroid Carcinoma -- 11. Aggressive Variants of Thyroid Carcinoma -- 12. Circulating Mucins and Cytokeratins in Aggressive Thyroid Cancers -- Part V. Thyroid Biomarkers on Fine-Needle Washouts -- 13. Measurement of Thyroid Tumor Markers on Fine-Needle Washouts -- Part VI. Neuroendocrine Tumors -- 14. Neuroendocrine Tumours: Diagnosis, Therapy and Follow-up -- 15. Circulating Markers in Neuroendocrine Tumors -- 16. Neuroendocrine Gene Transcripts: The Role of Molecular Biomarkers in Diagnosis and Management.
Format
e-Book
Publication Type
Atlas
Location
Online
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Controversies in Thyroid Surgery

https://libcat.nshealth.ca/en/permalink/provcat39824
John B. Hanks, William B. Inabnet III, editors. --Cham: Springer , c2016.
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This text encompasses many different thyroid diagnoses as well as several specialties of practicing surgeons in the United States. Over the last ten years many advances have been made in preoperative assessment including imaging and diagnostic techniques, operative approaches including "minimally invasive" and robotic surgery, and post-operative care. This volume also explores some of the controversies that arise as the result of these new findings and applications. The book is divided into two…
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Other Authors
Hanks, John B
Inabnet III, William B
Responsibility
John B. Hanks, William B. Inabnet III, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xiii, 233 p. : 74 illus., 56 illus. in color)
ISBN
9783319205236
9783319205229 (print ed.)
Subjects (MeSH)
Thyroid Diseases - diagnosis
Thyroid Gland - surgery
Thyroid Neoplasms - surgery
Thyroid Neoplasms - therapy
Thyroidectomy
Abstract
This text encompasses many different thyroid diagnoses as well as several specialties of practicing surgeons in the United States. Over the last ten years many advances have been made in preoperative assessment including imaging and diagnostic techniques, operative approaches including "minimally invasive" and robotic surgery, and post-operative care. This volume also explores some of the controversies that arise as the result of these new findings and applications. The book is divided into two categories of benign diagnosis and cancer topics. Both of these areas lend themselves to separate analysis of specific problems in the areas mentioned above. The text reviews recent data about advances in diagnostic techniques as well as outcomes with specific regards to the newer operative techniques in thyroid surgery. Controversies in Thyroid Surgery will serve as a resource for medical and surgical colleagues involved in the treatment of a wide variety of thyroid diseases.
Contents
Part I. General Topics -- Controversies in the Management of Nodular Thyroid Disease -- The Use of Ultrasound in the Management of Thyroid Disorders -- Pre and Post Thyroidectomy Voice Assessment -- Intraoperative Neuro-monitoring of the Laryngeal Nerves During Thyroidectomy -- Who Should Do Thyroid Surgery? -- Ambulatory Thyroid Surgery-Is This the Way of the Future? -- Robotic Thyroidectomy: Is There Still A Role? -- Graves' Disease-What is the Role and Timing of Surgery? -- Vocal Fold Paralysis and Thyroid Surgery -- Part II. Cancer Topics -- Optimal Treatment for Papillary Microcarcinoma -- Molecular Profiles and the "Indeterminate" Thyroid Nodule -- Controversies in the Surgical Management of Medullary Thyroid Carcinoma -- Central Lymph Node Dissection for Well-Differentiated Cancer -- The Role of Risk Stratification in the Treatment of Well Differentiated Thyroid Cancer -- Imaging for Preoperative Assessment and Staging of Thyroid Cancer -- Anaplastic Cancer and Rare Forms of Cancer Affecting the Thyroid -- The Role of Targeting Therapies or Non-Surgical Treatment of Thyroid Malignancies: Is Surgery Being Replaced?
Format
e-Book
Location
Online
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The diagnosis and management of thyroid carcinoma

https://libcat.nshealth.ca/en/permalink/provcat20945
Judith Czaja McCaffrey. --Alexandria, VA: American Academy of Otolaryngology--Head and Neck Surgery Foundation , 2002.
Call Number
WK 270 M121d 2002
Location
Dickson Building
Call Number
WK 270 M121d 2002
Author
McCaffrey, Judith Czaja, 1965-
Other Authors
American Academy of Otolaryngology--Head and Neck Surgery Foundation
Responsibility
Judith Czaja McCaffrey
Place of Publication
Alexandria, VA
Publisher
American Academy of Otolaryngology--Head and Neck Surgery Foundation
Date of Publication
2002
Physical Description
81 p.
Series Title
SIPac
Continuing education program
ISBN
9781567720471
1567720471
Subjects (MeSH)
Thyroid Gland - anatomy & histology
Thyroid Gland - physiology
Thyroid Neoplasms - diagnosis
Thyroid Neoplasms - therapy
Format
Book
Publication Type
Programmed Instruction
Location
Dickson Building
Loan Period
3 weeks
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Essentials of Thyroid Cancer Management

https://libcat.nshealth.ca/en/permalink/provcat30383
edited by Robert J. Amdur, Ernest L. Mazzaferri. --Boston, MA: Springer Science+Business Media , c2005.
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Online
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Author
Amdur, Robert J.
Other Authors
Mazzaferri, Ernest L.
Responsibility
edited by Robert J. Amdur, Ernest L. Mazzaferri
Place of Publication
Boston, MA
Publisher
Springer Science+Business Media
Date of Publication
c2005
Physical Description
1 online resource (xviii, 461 p.) : ill.
ISBN
9780387257143
Subjects (MeSH)
Thyroid Neoplasms - diagnosis
Thyroid Neoplasms - therapy
Contents
Introduction -- Diagnosis and Imaging of Thyroid Cancer -- Incidence and Prognosis of Differentiated Thyroid Cancer -- Surgical Therapy of Differentiated Thyroid Cancer -- Medical Therapy of Differentiated Thyroid Cancer -- Preparing Patients for I-131 Therapy -- Thyroid Remnant Ablation -- Suppression of Thyrotropin and the Potential Toxicity Of I-131 Therapy -- Follow-Up Protocol and Treatment of Recurrent or Metastatic Differentiated Thyroid Cancer -- Differentiated Thyroid Cancer During Pregnancy, in a Thyroglossal Duct, and Unfavorable Histologic Subtypes of DTC -- Medullary Thyroid Cancer -- External Beam Radiation Therapy -- Reference Information for Physicians and Patients.
Format
e-Book
Location
Online
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Management of Differentiated Thyroid Cancer

https://libcat.nshealth.ca/en/permalink/provcat41747
Anne T. Mancino, Lawrence T. Kim, editors. --Cham: Springer , 2017.
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This text provides a comprehensive, state-of-the art review of this field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in thyroid cancer. The book reviews new data about molecular genetics and molecular diagnostic approaches, covers diagnosis and treatment of localized disease, and conventional and newer therapies for dealing with recurrent and metastatic disease. Areas of controversy, with expert opinions from both outlooks, are also covered. Man…
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Other Authors
Mancino, Anne T
Kim, Lawrence T
Responsibility
Anne T. Mancino, Lawrence T. Kim, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xiii, 320 pages) : 88 illus., 64 illus. in color
ISBN
9783319544939
9783319544922 (print ed.)
Subjects (MeSH)
Thyroid Neoplasms - diagnosis
Thyroid Neoplasms - therapy
Abstract
This text provides a comprehensive, state-of-the art review of this field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in thyroid cancer. The book reviews new data about molecular genetics and molecular diagnostic approaches, covers diagnosis and treatment of localized disease, and conventional and newer therapies for dealing with recurrent and metastatic disease. Areas of controversy, with expert opinions from both outlooks, are also covered. Management of Differentiated Thyroid Cancer serves as a very useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up-to-date scientific and clinical information.
Contents
1. The Rising Incidence of Thyroid Cancer: Contributions from Healthcare Practice and Biologic Risk Factors -- 2. Molecular Genetics of Thyroid Cancer -- 3. Evaluation of a thyroid nodule -- 4. Pathologic diagnosis of thyroid cancer -- 5. Molecular Diagnostic Approaches and their Clinical Utility -- 6. Clinical Presentation and Diagnosis of Papillary Thyroid Cancer -- 7. Clinical Presentation and Diagnosis of Follicular Thyroid Cancer -- 8. Clinical Presentation and Diagnosis of Hrthle cell Thyroid Cancer -- 9. High Risk and Poorly Differentiated Thyroid Cancer -- 10. Pediatric Thyroid Cancer -- 11. Active Surveillance as the Initial Course of Action in low-risk papillary microcarcinoma -- 12. Surgical treatment of papillary and follicular thyroid cancer -- 13. Lymph node dissection for differentiated thyroid cancer -- 14. The Debate For Elective Lymph Node Dissection in Papillary Thyroid Carcinoma -- 15. The Debate against Elective Lymph Node Dissection in Papillary Thyroid Carcinoma -- 16. Differentiated Thyroid Cancer, Prognostic and Risk Assessment Systems -- 17. Radioactive Iodine as Adjuvant or Systemic Treatment -- 18. Considerations in thyrotropin stimulating hormone suppression in individuals with differentiated thyroid cancer -- 19. Imaging Modalities in the Diagnosis of Recurrent or Metastatic Thyroid Cancer -- 20. Operative Treatment of Recurrent or Metastatic Disease -- 21. Local and Systemic Treatment of Unresectable Disease -- 22. Surveillance Strategies After Initial Treatment of Differentiated Thyroid Cancer.
Format
e-Book
Location
Online
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Management of Thyroid Cancer and Related Nodular Disease

https://libcat.nshealth.ca/en/permalink/provcat30370
I. Ross McDougall ; with contribution by Gerald J. Berry. --London: Springer , c2006.
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Location
Online
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Author
McDougall, I. Ross
Other Authors
Berry, Gerald J.
Responsibility
I. Ross McDougall ; with contribution by Gerald J. Berry.
Place of Publication
London
Publisher
Springer
Date of Publication
c2006
ISBN
9781846280061
9781852339654 (print ed.)
Subjects (MeSH)
Thyroid Neoplasms - therapy
Thyroid Nodule - therapy
Subjects (LCSH)
Endocrinology 
Oncology
Format
e-Book
Location
Online
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Management of thyroid cancer and related nodular disease

https://libcat.nshealth.ca/en/permalink/provcat22577
I. Ross McDougall ; with contribution by Gerald J. Berry. --London, England: Springer , 2006.
Call Number
WK 270 M137m 2006
Location
Halifax Infirmary
Call Number
WK 270 M137m 2006
Author
McDougall, I. Ross
Other Authors
Berry, Gerald J.
Responsibility
I. Ross McDougall ; with contribution by Gerald J. Berry
Place of Publication
London, England
Publisher
Springer
Date of Publication
2006
Physical Description
ix, 397 p. : ill. (some col.)
ISBN
1852339659
9781852339654
Subjects (MeSH)
Thyroid Neoplasms - therapy
Thyroid Nodule - therapy
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Management of Thyroid Cancer : Special Considerations

https://libcat.nshealth.ca/en/permalink/provcat39512
K. Alok Pathak, Richard W. Nason, Janice L. Pasieka, editors. --New Delhi: Byword Books ; Springer , c2015.
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Thyroid cancer is the most common malignant endocrine tumour. The incidence of thyroid cancer has been increasing more rapidly than any other cancer in many of the cancer registries from different parts of the world. Although the majority of thyroid cancers have an indolent biological behavior, different histological types have a diverse clinical behavior. Well-differentiated thyroid cancers have an excellent survival, whereas poorly differentiated and anaplastic thyroid cancers have a very poo…
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Other Authors
Pathak, K. Alok
Nason, Richard W.
Pasieka, Janice L.
Responsibility
K. Alok Pathak, Richard W. Nason, Janice L. Pasieka, editors
Place of Publication
New Delhi
Publisher
Byword Books ; Springer
Date of Publication
c2015
Physical Description
1 online resource (xvi, 145 p.) : 14 illus., 11 illus. in color
Series
Head and Neck Cancer Clinics
Series Title
Head and neck cancer clinics (Series)
ISBN
9788132224341
9788132224334 (print ed.)
ISSN
2364-4060
Subjects (MeSH)
Thyroid Neoplasms - therapy
Abstract
Thyroid cancer is the most common malignant endocrine tumour. The incidence of thyroid cancer has been increasing more rapidly than any other cancer in many of the cancer registries from different parts of the world. Although the majority of thyroid cancers have an indolent biological behavior, different histological types have a diverse clinical behavior. Well-differentiated thyroid cancers have an excellent survival, whereas poorly differentiated and anaplastic thyroid cancers have a very poor outcome. This volume of Head and Neck Cancer Clinics addresses advances, controversies and state-of-the-art treatment recommendations of various types of thyroid cancers.
Contents
Molecular risk stratification of well-differentiated thyroid cancer -- The significance of cervical lymph nodes in well-differentiated thyroid cancer -- Management of the central compartment in well-differentiated thyroid carcinoma -- Management of the lateral neck in well-differentiated thyroid cancer -- The management of recurrent/persistent well-differentiated thyroid cancer in the central compartment -- Management of distant metastases in differentiated thyroid cancer -- Risk-adjusted strategies in post-treatment surveillance of well-differentiated thyroid carcinoma -- Medullary thyroid cancer -- Anaplastic thyroid cancer: Current concepts -- External beam radiotherapy for thyroid cancer -- Targeted therapies in thyroid cancer.
Format
e-Book
Location
Online
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Management of Thyroid Nodules and Differentiated Thyroid Cancer : A Practical Guide

https://libcat.nshealth.ca/en/permalink/provcat41487
Sanziana A. Roman, Julie Ann Sosa, Carmen C. Solórzano, editors. --Cham: Springer , 2017.
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This book provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians and researchers with an interest in the management of thyroid nodules and cancer, including both surgeons and endocrinologists. The book reviews new data about risk factors for nodular disease and cancer, details the management of toxic and non-toxic benign thyroid nodular disease, discusses controversies in the management of indeterminate thyroid nodules and cancer, a…
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Other Authors
Roman, Sanziana A.
Sosa, Julie Ann
Solórzano, Carmen C.
Responsibility
Sanziana A. Roman, Julie Ann Sosa, Carmen C. Solórzano, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xiv, 459 pages) : 80 illus., 62 illus. in color
ISBN
9783319436180
9783319436166 (print ed.)
Subjects (MeSH)
Thyroid Neoplasms - diagnosis
Thyroid Neoplasms - therapy
Thyroid Nodule - diagnosis
Thyroid Nodule - therapy
Abstract
This book provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians and researchers with an interest in the management of thyroid nodules and cancer, including both surgeons and endocrinologists. The book reviews new data about risk factors for nodular disease and cancer, details the management of toxic and non-toxic benign thyroid nodular disease, discusses controversies in the management of indeterminate thyroid nodules and cancer, and reviews the latest data on use of molecular testing for diagnosis and prognosis. Lastly, the book reviews the management of difficult-to-treat thyroid cancers. Management of Thyroid Nodules and Differentiated Thyroid Cancer: A Practical Guide will serve as a useful resource for physicians and researchers dealing with, and interested in thyroid nodular disease and cancer. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.
Contents
1. Incidence and Epidemiology -- Part I The Thyroid Nodule -- 2. The Clinically Detected and Palpable Thyroid Nodule -- 3. Ultrasound of the Thyroid and Soft Tissues of the Neck -- 4. Thyroid Nodule Biopsy -- 5. The Bethesda System for Reporting Thyroid Cytopathology (BSRTC) -- 6. Cross-Sectional Imaging for the Evaluation of Thyroid Nodules and Cancer -- 7. Surveillance of Benign Thyroid Nodules -- Part II: Management of Nodular Hyperthyroidism -- 8. The Role of Medical Management for Nodular Hyperthyroidism -- 9. The Role of Surgery for Nodular Hyperthyroidism -- Part III: The Indeterminate Thyroid Nodule -- 10. Surgical Intervention for Indeterminate Thyroid Nodules -- Part IV Papillary Thyroid Cancer -- 11. Staging for Papillary Thyroid Cancer -- 12. Importance of Surgeon Experience in the Surgical Management of Thyroid Cancer -- 13. The Pediatric Thyroid Nodule and Papillary Thyroid Cancer Management -- Part V: Controversies in Papillary Thyroid Cancer -- 14. Papillary Thyroid Microcarcinomas -- 15. Surgical Management of Low-Risk Papillary Thyroid Cancer -- 16. Management of Central Compartment Lymph Nodes in Patients with Papillary Thyroid Carcinoma -- 17. The Management of the Persistent and Recurrent Cervical Lymph Node Metastases -- 18. Thyroid Nodular Disease and Thyroid Cancer During Pregnancy -- 19. The Perioperative Management of the Voice and Serum Calcium Levels -- Part VI: Post-thyroidectomy Radioiodine Therapy, Hormonal Therapy and Surveillance -- 20. Initial Radioiodine Ablation -- 21. Treatment of Recurrent/Metastatic Thyroid Cancer with Radioactive Iodine -- 22. Surveillance of Treated Thyroid Cancer Patients and Thyroid Hormone Replacement and Suppression -- 23. Integrative Approaches to Patients Undergoing Thyroid Surgery -- Part VII: Other Differentiated and Advanced Thyroid Cancer -- 24. Follicular and Hürthle Cell Carcinoma -- 25. Locally Advanced Differentiated Thyroid Cancer -- 26. External Beam Radiation for Locally Advanced and Metastatic Differentiated Thyroid Cancer -- 27. Systemic Therapy for Advanced Metastatic Thyroid Cancer.
Format
e-Book
Location
Online
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Medullary Thyroid Cancer

https://libcat.nshealth.ca/en/permalink/provcat40272
Tracy S. Wang, Douglas B. Evans, editors. --Cham: Springer , c2016.
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This text provides a comprehensive, contemporary review of this disease and serves as an important resource for clinicians and researchers with an interest in medullary thyroid cancer. The book reviews the initial management of the patient with thyroid nodules, including risk factors, appropriate genetic evaluation of suspected/known medullary thyroid cancer, and appropriate screening for diseases associated with inherited forms of medullary thyroid cancer, including primary hyperparathyroidism…
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Other Authors
Wang, Tracy S.
Evans, Douglas B. (Douglas Brian) 1956-
Responsibility
Tracy S. Wang, Douglas B. Evans, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xi, 205 p. : 40 illus., 28 illus. in color)
ISBN
9783319394121
9783319394107 (print ed.)
Subjects (MeSH)
Carcinoma, Medullary - diagnosis
Carcinoma, Medullary - genetics
Carcinoma, Medullary - therapy
Thyroid Neoplasms - diagnosis
Thyroid Neoplasms - genetics
Thyroid Neoplasms - therapy
Abstract
This text provides a comprehensive, contemporary review of this disease and serves as an important resource for clinicians and researchers with an interest in medullary thyroid cancer. The book reviews the initial management of the patient with thyroid nodules, including risk factors, appropriate genetic evaluation of suspected/known medullary thyroid cancer, and appropriate screening for diseases associated with inherited forms of medullary thyroid cancer, including primary hyperparathyroidism and pheochromocytomas. It includes an in-depth discussion of the optimal surgical management of patients with sporadic and inherited disease, those with locoregional metastases, distant metastases, and recurrent medullary thyroid cancer. The long-term follow-up and management of patients with medullary thyroid cancer is highlighted. Medullary Thyroid Cancer will serve as a useful resource for all providers and researchers interested in this relatively rare and challenging malignancy. It highlights recent guidelines for the management of patients with medullary thyroid cancer and discusses controversies within the literature. All chapters are written by experts in the field and incorporate multiple disciplines, including Surgery (Endocrine Surgery, General Surgery, and Otolaryngology), Endocrinology, Radiology, Medical Oncology and Genetic Counseling.
Contents
[publisher suppplied] History and Epidemiology -- Cytology and Pathology: Pitfalls and Challenges -- Initial Evaluation and Diagnosis of Medullary Thyroid Cancer -- Molecular Mechanisms of Disease: The RET Proto-Oncogene -- Genetic Evaluation of the Patient with Medullary Thyroid Cancer -- Preoperative Evaluation of Medullary Thyroid Cancer -- Surgical Management of Inherited MTC: Prophylactic Thyroidectomy -- Surgical Management of Inherited MTC: Therapeutic Thyroidectomy -- Surgical Management of the Parathyroid Glands in Patients with Inherited MTC -- Surgical Management of Sporadic MTC -- The Role for External Beam Radiation Therapy -- Management of Patients with Metastatic MTC -- Emerging Therapies for Progressive Metastatic MTC -- Follow-Up and Surveillance of Patients with MTC -- Surgical Management of Recurrent MTC.
Format
e-Book
Location
Online
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Practical Management of Thyroid Cancer : A Multidisciplinary Approach

https://libcat.nshealth.ca/en/permalink/provcat42585
Ujjal K. Mallick, Clive Harmer, editors. (Second edition) --Cham: Springer , c2018.
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The new edition of this book highlights the recent advances and state-of-the art in surgical and non-surgical management of thyroid cancer. Readers will learn about the latest advances and recommendations in the field, from molecular studies and biomarkers to the changing epidemiology, kinase inhibition in drug discovery and new surgical approaches, such as intra-operative neural monitoring and robotics. The management of differentiated thyroid cancer as well as childhood cancer, survivorship a…
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Other Authors
Mallick, Ujjal K.
Harmer, Clive
Responsibility
Ujjal K. Mallick, Clive Harmer, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xvi, 395 p.) : 79 illus., 30 illus. in color
ISBN
9783319917252
9783319917245 (print ed.)
9783319917269 (print ed.)
Subjects (MeSH)
Patient Care Team
Thyroid Neoplasms - therapy
Specialty
Endocrinology
Abstract
The new edition of this book highlights the recent advances and state-of-the art in surgical and non-surgical management of thyroid cancer. Readers will learn about the latest advances and recommendations in the field, from molecular studies and biomarkers to the changing epidemiology, kinase inhibition in drug discovery and new surgical approaches, such as intra-operative neural monitoring and robotics. The management of differentiated thyroid cancer as well as childhood cancer, survivorship and clinical trial design and findings and how these fit into cancer management are discussed in detail. This comprehensive volume provides an overview of the current world literature and outlines the practical aspects of management from world leaders in this field and helps clinicians and patients on practical matters. With a selection of authors from around the world it draws on international experience giving a global perspective to the topic. Following on from the success of the first edition, it uses a multidisciplinary, evidence-based approach centered on the patient, discussing guidelines and how these have improved the quality of care and outcomes. This guide is aimed mainly at thyroidologists of all disciplines, (in training or experts) students, non-specialist clinicians, nursing staff, all the disciplines involved in a multidisciplinary team such as surgeons—Head & Neck or Endocrine and General Surgeons, Oncologists, Endocrinologists, Nuclear Medicine Physicians, Nuclear Medicine Physicists, Radiologists, Pathologists, Specialist Nurses, Geneticists, Clinical Psychologists, Palliative Care Physicians and, of course, patients.
Contents
1. Pragmatism, Precision Oncology, International Partnership for Research and Quality-The New Paradigm for Thyroid Cancer -- Part I. Multidisciplinary Approach to Management of Thyroid Cancer -- 2. The UK Evidence-Based Guidelines for the Management of Thyroid Cancer: Key Recommendations -- 3. The 2015 American Thyroid Association Evidence-Based Guidelines for Management of Patients with Thyroid Nodules and Differentiated Thyroid Cancer: Key Recommendations -- 4. Thyroid Cancer: One Doctor-Patient Partnership -The Newcastle Butterfly Model -- Part II. The Diagnosis of Thyroid Cancer -- 5. Molecular Diagnosis of Thyroid Nodules -- 6. Ultrasonography in Diagnosis and Management of Thyroid Cancer ÇôCurrent International Recommendations -- Part III. Initial Thyroid Surgery -- 7. The 21st Century Endocrine Surgeon -- 8. Management of Cervical Lymph Nodes in Differentiated Thyroid Cancer -- 9. Advances in Thyroid Surgery -- Part IV. Non surgical Management of Differentiated Thyroid Cancer -- 10. Risk Stratification and Current Management of Low Risk Thyroid Cancer -- 11. Management of Low risk Papillary Thyroid Carcinomo and Papillary Cancer and Microcarcinoma-the Japanese experience -- 12. Radioiodine Ablation—Current Status -- 13. Dosimetric Approaches—Current Concepts -- 14. External Radiation in Differentiated Thyroid Cancer in the era of IMRT and modern radiation planning techniques -- Part V. Follow up and Longterm Management of Differentiated Thyroid Cancer -- 15. Thyroglobulin -- 16. Management of Post-Operative Hypocalcemia -- 17. Radioiodine Refractory Thyroid Cancer -- Part VI. Medullary Thyroid Carcinoma -- 18. Medullary Thyroid Cancer :Surgical Management -- 19. Medullary Thyroid Cancer: Diagnosis and Non Surgical Management -- 20. Familial Non-Medullary Thyroid Cancer -- Part VII. Thyroid Cancer in Children -- 21. Pediatric Differentiated Thyroid Carcinoma -- Part VIII. Aggressive Thyroid Cancers -- 22. Anaplastic Thyroid Cancer -- 23. Palliative care -- Part IX. Future Developments and Directions for Research in Thyroid Cancer -- 24. Translational Research and Genomics Driven Trials in Thyroid Cancer -- 25. Thyroid Cancer Trials -- 26. The Barriers to Uniform Implementation of Clinical Practice Guidelines (CPG) for Thyroid Cancer -- 27. Survivorship: The Role of the Clinical Psychologist and the Clinical Nurse Specialist in Thyroid Cancer Care.
Format
e-Book
Location
Online
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The Thyroid and Its Diseases : A Comprehensive Guide for the Clinician

https://libcat.nshealth.ca/en/permalink/provcat44231
Markus Luster, Leonidas H. Duntas, Leonard Wartofsky, editors. --Cham: Springer , 2019.
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This book is an up-to-date and comprehensive guide to all the common thyroid disorders that may be seen by internists, endocrinologists, nuclear medicine physicians, and endocrine surgeons. While the fundamentals of thyroid hormone function and regulation in health and disease are well covered, the primary focus is on the clinical approach to thyroid disease, with detailed coverage of both initial diagnosis and management and the role of imaging. Because most endocrine diseases are chronic and …
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Other Authors
Luster, Markus
Duntas, Leonidas H.
Wartofsky, Leonard
Responsibility
Markus Luster, Leonidas H. Duntas, Leonard Wartofsky, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (xiv, 770 p.) : 192 illus., 130 illus. in color
ISBN
9783319721026
9783319721002 (Print ed.)
9783319721019 (Print ed.)
Subjects (MeSH)
Thyroid Gland - anatomy & histology
Thyroid Gland - pathology
Thyroid Diseases - physiopathology
Thyroid Diseases - therapy
Thyroid Neoplasms - physiopathology
Thyroid Neoplasms - therapy
Specialty
Endocrinology
Abstract
This book is an up-to-date and comprehensive guide to all the common thyroid disorders that may be seen by internists, endocrinologists, nuclear medicine physicians, and endocrine surgeons. While the fundamentals of thyroid hormone function and regulation in health and disease are well covered, the primary focus is on the clinical approach to thyroid disease, with detailed coverage of both initial diagnosis and management and the role of imaging. Because most endocrine diseases are chronic and lifelong, special emphasis is placed on long-term management and the common pitfalls that may be encountered by the clinician. The editors are internationally acknowledged leaders in the field of thyroid disease and have gathered an outstanding team of authors, all of whom are also highly expert in their respective areas, but who, equally importantly, write in a clear and lucid style. The numerous isotope scan and ultrasonographic images ensure that the book will serve as a valuable reference atlas to which the physician will return again and again.
Contents
PART I. INTRODUCTION -- Anatomy and physiology of the thyroid gland -- The Hypothalamic-pituitary-thyroid axis: physiological regulation and clinical implications -- Thyroglobulin storage and degradation for thyroid hormone liberation -- Disorders of thyroid hormone transporters and receptors -- Deiodination and peripheral metabolism of thyroid hormone -- PART II. BASIS OF THYROID DISEASE -- Epidemiology of thyroid diseases -- Classification of thyroid diseases -- Iodine deficiency -- Selenium deficiency and thyroid disease -- PART III. DIAGNOSTIC & THERAPEUTIC APPROACHES -- Laboratory testing in thyroid disorders -- Ultrasonography of the thyroid and cervical lymph nodes -- The role of elastography in the management of thyroid nodules -- DTC imaging with Iodine-124 and F-18-FDG -- Surgery for benign goiter -- PART IV. HYPOTHYROIDISM -- The thyroid and its regulation by the TSHR: evolution, development and congenital defects -- Hypothyroidism -- Central hypothyroidism -- Subclinical hypothyroidism -- Treatment of hypothyroidism -- Myxedema coma -- Heart in Hypothyroidism -- PART V. HYPERTHYROIDISM -- Graves’ disease -- Graves’ ophthalmopathy -- Subclinical hyperthyroidism -- Thyroid storm -- Heart in Hyperthyroidism -- PART VI. THYROIDITIS -- Chronic autoimmune thyroiditis -- Acute infectious thyroiditis (Acute suppurative thyroiditis) -- Postpartum thyroiditis -- Amiodarone-induced thyroid dysfunction -- Iodine-induced thyroid dysfunction -- PART VII. THYROID NEOPLASIA -- Pathology of the thyroid: a review -- Thyroid nodules: current evaluation & management -- Non-toxic multinodular goiter -- PART VIII. THYROID CANCER -- Epidemiology of thyroid cancer -- Molecular genetics and diagnostics of thyroid cancer -- Thyroid cancer in children and Adolescents -- Thyroid cancer surgery -- Staging and prognosis of thyroid cancer -- Radioiodine therapy in differentiated thyroid carcinoma -- Dosimetry for 131I therapy for metastatic differentiated thyroid cancer -- Thyroid cancer: targeted molecular therapy -- Thyroid cancer: thyroglobulin & TgABs -- Medullary thyroid cancer -- Anaplastic thyroid carcinoma -- Primary thyroid lymphoma -- The role of TSH suppression in the management of differentiated thyroid cancer -- PART IX. MISCELANEOUS TOPICS -- Hyperthyroidism and pregnancy -- Thyroid hormone resistance syndromes.
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e-Book
Location
Online
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edited by H.-J. Biersack, F. Grünwald. (2nd ed.) --Berlin, Heidelberg: Springer-Verlag , c2005.
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Location
Online
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Author
Biersack, H.-J
Other Authors
Grünwald, F
Responsibility
edited by H.-J. Biersack, F. Grünwald
Edition
2nd ed.
Place of Publication
Berlin, Heidelberg
Publisher
Springer-Verlag
Date of Publication
c2005
Physical Description
1 online resource (xxiii, 363 p.) : ill.
ISBN
9783540278450
Subjects (MeSH)
Thyroid Neoplasms - diagnosis
Thyroid Neoplasms - therapy
Format
e-Book
Location
Online
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Thyroid Cancer : A Case-Based Approach

https://libcat.nshealth.ca/en/permalink/provcat46517
Giorgio Grani, David S. Cooper, Cosimo Durante, editors. (Second edition) --Cham: Springer , c2021.
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Access
NEW Springer 2021
Location
Online
Now in its second edition utilizing brand new clinical case material, this popular, user-friendly text presents the diagnosis and treatment of thyroid cancer and related clinical issues, providing clinicians in endocrinology and oncology with the best real-world strategies to properly manage the various manifestations of thyroid cancer that they may encounter. Each chapter is a case report that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and…
Available Online
View e-Book
Other Authors
Grani, Giorgio
Cooper, David S.
Durante, Cosimo
Responsibility
Giorgio Grani, David S. Cooper, Cosimo Durante, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2021
Physical Description
1 online resource (xvii, 403 p.) : 60 illus., 38 illus. in color
ISBN
9783030619190
9783030619183 (Print ed.)
9783030619206 (Print ed.)
9783030619213 (Print ed.)
Subjects (MeSH)
Thyroid Neoplasms - diagnosis
Thyroid Neoplasms - therapy
Specialty
Endocrinology
Medical Oncology
Abstract
Now in its second edition utilizing brand new clinical case material, this popular, user-friendly text presents the diagnosis and treatment of thyroid cancer and related clinical issues, providing clinicians in endocrinology and oncology with the best real-world strategies to properly manage the various manifestations of thyroid cancer that they may encounter. Each chapter is a case report that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and therapy, as well as the case outcome, literature review, clinical pearls and pitfalls, and bibliography. All recommendations are based on evidence-based clinical practice guidelines and recent literature. Written by experts in the field, these cases illustrate treatment for both low- and high-risk differentiated thyroid cancer, including surgical approaches, radioiodine therapy, and novel chemotherapies and targeted therapies, as well as postoperative follow-up and special issues. Additional cases demonstrate the management of medullary thyroid cancer and anaplastic thyroid cancer. Topics new to the second edition include information on management of small thyroid cancers with “active surveillance” (without surgery), new chemotherapeutic approaches to advanced thyroid cancer, and new information on a lesion that is no longer considered to be thyroid cancer (Neoplastic Follicular Thyroid Neoplasm with Papillary-Like Features [NIFTP]), as well as material on external beam radiotherapy and new approaches to the management of anaplastic thyroid cancer. Pragmatic and reader-friendly, this second edition of Thyroid Cancer: A Case-Based Approach will be an excellent resource for clinical endocrinologists and oncologists, endocrine fellows, residents and students alike.
Contents
Part I. Differentiated Thyroid Cancer: Initial Management -- Part II. Differentiated Thyroid Cancer: Postoperative Follow-Up -- Part III. Differentiated Thyroid Cancer: Special Issues -- Part IV. Differentiated Thyroid Cancer: Managing higher risk patients -- Part V. Differentiated Thyroid Cancer: Beyond Radioactive Iodine Therapy -- Part VI. Medullary Thyroid Cancer -- Part VII. Anaplastic Thyroid Cancer.
Access
NEW Springer 2021
Format
e-Book
Publication Type
Case Reports
Location
Online
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Thyroid Cancer : A Case-Based Approach

https://libcat.nshealth.ca/en/permalink/provcat39878
David S. Cooper, Cosimo Durante, editors. (1st ed.) --Cham: Springer , c2016.
Available Online
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Location
Online
Comprised exclusively of clinical cases covering the diagnosis and treatment of thyroid cancer and related clinical issues, this concise, practical casebook will provide clinicians in endocrinology and oncology with the best real-world strategies to properly manage the various forms of thyroid cancer that they may encounter. Each chapter is a case report, written by recognized experts, that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and the…
Available Online
View e-Book
Other Authors
Cooper, David S.
Durante, Cosimo
Responsibility
David S. Cooper, Cosimo Durante, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xvii, 430 p.) : 46 illus., 27 illus. in color
ISBN
9783319224015
9783319224008 (print ed.)
Subjects (MeSH)
Thyroid Neoplasms - therapy
Abstract
Comprised exclusively of clinical cases covering the diagnosis and treatment of thyroid cancer and related clinical issues, this concise, practical casebook will provide clinicians in endocrinology and oncology with the best real-world strategies to properly manage the various forms of thyroid cancer that they may encounter. Each chapter is a case report, written by recognized experts, that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and therapy, as well as the case outcome, literature review, clinical pearls and pitfalls, and bibliography. All recommendations are based on evidence-based clinical practice guidelines and recent literature. Cases included illustrate treatment for both low and high risk differentiated thyroid cancer, including surgical approaches, radioiodine therapy, and novel chemotherapies and targeted therapies, as well as postoperative follow-up and special issues. Additional cases demonstrate the management of medullary thyroid cancer, thyroid lymphoma and anaplastic thyroid cancer. Pragmatic and reader-friendly, Thyroid Cancer: A Case-Based Approach will be an excellent resource for clinical endocrinologists and oncologists, endocrine fellows, residents and students alike.
Contents
Part I. Low Risk Differentiated Thyroid Cancer: Preoperative Diagnosis -- 1 A patient with a single thyroid nodule suspicious for follicular neoplasm according to the Bethesda System for Reporting Thyroid Cytopathology: molecular evaluation -- Part II. Low Risk Differentiated Thyroid Cancer: Initial management, extent of surgery and use of radioactive iodine therapy -- 2 A case of a small (1 to 2 cm) papillary thyroid cancer in a young patient: lobectomy vs. total thyroidectomy -- 3 The decision-making process for prophylactic central neck dissection in a patient presenting with nodular thyroid disease suspicious for malignancy on cytology assessment: role of preoperative ultrasound and molecular marker testing -- 4 Incidentally discovered micropapillary thyroid cancer -- 5 Completion thyroidectomy in a patient with low risk papillary cancer -- 6 A case of multifocal micropapillary thyroid cancer -- 7 A papillary thyroid cancer with minimal extra-thyroidal extension -- 8 A case of a papillary thyroid cancer with lymph node metastases found on prophylactic central neck dissection (subclinical disease, micrometastases) -- 9 Papillary thyroid cancer with central neck lymph node metastases -- 10 A patient with a large minimally invasive follicular thyroid cancer -- 11 A young patient with intrathyroidal papillary thyroid cancer and family history of differentiated thyroid cancer -- 12 A child with papillary thyroid cancer and locally advanced disease but no distant metastasis -- Part III. Low Risk Differentiated Thyroid Cancer: Postoperative follow-up -- 13 A patient with papillary thyroid cancer and biochemical evidence of disease at the 1-yr follow-up visit -- 14 Low but detectable suppressed thyroglobulin levels in thyroid cancer patients' follow-up: How to interpret and manage these cases? -- 15 A young patient with papillary thyroid cancer and biochemical evidence of disease at the follow-up visits and increasing serum Tg values at the follow up assessments -- 16 A young patient with recurrent lymph node involvement: imaging, cytology, Tg washout -- Part IV. Low Risk Differentiated Thyroid Cancer: Special issues -- 17 Papillary thyroid carcinoma diagnosed during pregnancy -- 18 Risks of Thyroid Hormone Suppression for Differentiated Thyroid Cancer in the Elderly -- 19 A patient in whom one pathologist says she has cancer and another says that the lesion is benign -- 20: A case with postsurgical hypoparathyroidism -- 21 A case with postsurgical recurrent laryngeal nerve damage and nerve monitoring -- Part V. High Risk Differentiated Thyroid Cancer: The need for additional therapy -- 22 A case of papillary thyroid cancer without aggressive histological features with nodal metastases detected during follow-up in a younger patient -- 23 A case of papillary thyroid cancer without aggressive histological features with nodal metastases in an older patient -- 24 A patient with a large H¿rthle cell carcinoma of the thyroid and nodal metastases -- 25 A case of a large, invasive PTC with gross residual disease (pT4) after surgery -- Part VI. High Risk Differentiated Thyroid Cancer: The use of radioiodine -- 26 A patient with papillary carcinoma of the thyroid with elevated serum thyroglobulin but negative imaging studies -- 27 A young child with papillary thyroid cancer and metastatic pulmonary disease:á whole issue of radioactive iodine therapy in children -- 28 A patient with bone metastases from follicular carcinoma of the thyroid -- 29 Radioiodine Therapy in Lactating Women with High Risk Differentiated Thyroid Cancer -- Part VII. High Risk Differentiated Thyroid Cancer: The use of local treatments and novel systemic chemotherapies -- 30 A case of a patient with radioactive iodine refractory differentiated thyroid cancer with progressive neck disease (latero-cervical lymph nodes) and stable, small lung metastases -- 31 A case of an elderly patient with advanced disease and non radioiodine avid metastases -- 32 Radioactive iodine refractory differentiated thyroid cancer with multiple organ progressive disease -- 33 Radioactive iodine refractory differentiated thyroid cancer and lung lesions causing bleeding -- 34 A patient with follicular thyroid cancer and a painful bone metastasis at risk for pathologic fracture -- 35 Differentiated thyroid cancer and brain -- Part VIII. High Risk Differentiated Thyroid Cancer: Novel chemotherapy and toxicity -- 36 Radioactive iodine refractory, advanced differentiated thyroid cancer receiving tyrosine kinase inhibitor treatment: checking for drug-drug interactions -- 37 A patient with advanced differentiated radioactive iodine-refractory thyroid cancer receiving tyrosine kinase inhibitor treatment: managing hypertension, QTc prolongation, dermatologic and gastrointestinal adverse events -- Part IX. Medullary Thyroid Cancer: Postoperative management -- 38 Management of post-operative hypercalcitoninemia in medullary thyroid cancer -- 39 A patient with metastatic medullary thyroid carcinoma (MTC) and tumor-related diarrhea -- 40 Clinical management of a patient with a locally recurrent medullary thyroid cancer and asymptomatic slowly progressing distant metastases -- 41 A patient with an advanced medullary thyroid cancer and progressive, symptomatic distant metastases: when to start systemic therapy -- 42 Medical Treatment Decision-Making for Advanced, Progressive Medullary Thyroid Cancer -- Part X. Medullary Thyroid Cancer: Special issues -- 43 Screening leading to diagnosis of C cell hyperplasia -- 44 Increased basal calcitonin in nodular goiter: Is it micromedullary thyroid cancer? -- 45 Timing and extent of surgery for a pediatric patient with hereditary MTC and positive screening for the S891A RET mutation -- Part XI. Thyroid lymphoma -- 46 Thyroid Lymphoma: Differential Diagnosis -- Part XII. Anaplastic thyroid cancer -- 47 Anaplastic Thyroid Cancer: Surgery or Not in Locally Advanced Disease.
Format
e-Book
Publication Type
Case Reports
Location
Online
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Treatment of thyroid tumor : Japanese clinical guidelines

https://libcat.nshealth.ca/en/permalink/provcat32523
Hiroshi Takami, editor-in-chief ; Yasuhiro Ito, Hitoshi Noguchi, Akira Yoshida ... [et al.], editors. --Tokyo: Springer , c2013.
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Location
Online
Creating clinical guidelines is a modern trend. Published studies pertaining to a given theme are collected, their credibility evaluated, and then treatment options in the form of evidence-based guidelines are offered. There are a number of guidelines for the treatment of thyroid tumors that have established positions in clinical practice in North America and in Western European countries. In Japan, however, where radioisotope facilities are of limited availability, treatment plans for differen…
Available Online
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Other Authors
Takami, Hiroshi
Responsibility
Hiroshi Takami, editor-in-chief ; Yasuhiro Ito, Hitoshi Noguchi, Akira Yoshida ... [et al.], editors
Place of Publication
Tokyo
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xviii, 310 p. : 16 ill., 9 ill. in color)
ISBN
9784431540496
Subjects (MeSH)
Japan
Thyroid Neoplasms - surgery
Thyroid Neoplasms - therapy - Practice Guideline
Subjects (LCSH)
Endocrinology 
Oncology
Surgery
Notes
"English translation based on the Japanese original Kojyosen shuyo shinryo guideline 2010." --T.p. verso
Abstract
Creating clinical guidelines is a modern trend. Published studies pertaining to a given theme are collected, their credibility evaluated, and then treatment options in the form of evidence-based guidelines are offered. There are a number of guidelines for the treatment of thyroid tumors that have established positions in clinical practice in North America and in Western European countries. In Japan, however, where radioisotope facilities are of limited availability, treatment plans for differentiated thyroid cancer differ considerably from those of America and Europe, and the associated clinical guidelines need modification before they can be adopted. In addition, although thyroid tumor is a common disease in endocrine practice, its management can differ even among specialists. Thus, a Japanese clinical guideline for the treatment of thyroid tumor was desired by many clinicians. As a combination of evidence-based and consensus-based guidelines for the treatment of thyroid tumor, this book offers alternatives to conventional approaches in the West. Ultimately, the authors hope the guideline will lead to the best possible treatment for patients all over the world in the not-distant future.
Format
e-Book
Location
Online
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