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Manual of pediatric hematology and oncology

https://libcat.nshealth.ca/en/permalink/provcat31570
Philip Lanzkowsky. (5th ed.) --London: Academic , 2010.
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This will be the fifth edition of successful clinical manual aimed at all practitioners treating children with cancer and blood diseases, such as leukemia, anemia, and bone marrow failure. As with previous editions, this edition will be a comprehensive book on patient management, replete with algorithms and flow diagrams on diagnosis and management. Its concise and easy-to-read format will enable readers to make accurate diagnoses and permit them to treat patients even if they have not had exte…
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Author
Lanzkowsky, Philip
Responsibility
Philip Lanzkowsky
Edition
5th ed.
Place of Publication
London
Publisher
Academic
Date of Publication
2010
Physical Description
1 online resource
ISBN
9780123751546 (electronic bk.)
Subjects (MeSH)
Pediatrics
Hematology
Subjects (LCSH)
Hematologic Diseases
Child
Infant
Neoplasms
Pediatric hematology
Tumors in children
Abstract
This will be the fifth edition of successful clinical manual aimed at all practitioners treating children with cancer and blood diseases, such as leukemia, anemia, and bone marrow failure. As with previous editions, this edition will be a comprehensive book on patient management, replete with algorithms and flow diagrams on diagnosis and management. Its concise and easy-to-read format will enable readers to make accurate diagnoses and permit them to treat patients even if they have not had extensive previous hematologic or oncologic experience. It will contain a list of normal values at various ages in children, which is extremely useful as a reference in the management of patients. Since the previous edition was written five years ago, there have been considerable advances particularly in the treatment and management of oncologic diseases in children. These oncology sections (approximately 40% of the book) will be entirely rewritten to incorporate all current protocols. In addition, advances in many other areas will require that all hematology sections of the book be updated. The successful basic format and content of clinical manifestations, diagnosis and differential diagnosis will be maintained - as in previous editions, the editor will closely edit chapter content to maintain consistency in format, depth, and style. In addition to the core group of hematologists and oncologists from Schneider Children's Hospital, who contributed to the 4th edition, the editor is inviting 15 new authors who are all experts from around the country - in order to keep up with the advances in management of hem/onc diseases. The book will reflect the 45+ years of practical experience by the editor as well as the extensive clinical experience and research expertise of the various contributors. Feature Offers a concise, systematic approach to all pediatric hematologic and oncologic disorders in one reference manual Easy-to-read format: multiple tables, charts, and flow-diagrams for diagnosis and management of pediatric hematologic and oncologic disorders Clear presentation by practicing clinicians, who are also academic researchers, of recent developments in molecular genetics, cytogenetics, immunology, transplantation, and biochemistry to the extent that they have bearing on clinical practice Benefits Practitioners responsible for the care of children with hem/onc diseases will save time going to one concise, authoritative source for diagnosis and treatment options, without having to wade through all the details in larger tomes on hematology or oncology, or in thousands of journal articles Residents will use it as a guide to prepare for board examinations in pediatric hematology/oncology, pediatrics, hematology, and oncology Practicing pediatricians, hematologists, oncologists, fellows, and pediatric nurses will use it a quick source for a second opinion in diagnosis and disease management when they are unable to consult with a pediatric hem/onc specialist Practicing pediatric hem/onc specialists will use the book as a "refresher course" and will appreciate the systematic approach For all practitioners, correct diagnosis (and therefore correct treatment) of oncologic and hematologic diseases depends on a strong understanding of the molecular basis for the disease
Contents
Classification and Diagnosis of Anemia During Childhood -- Anemia During the Neonatal Period -- Iron-Deficiency Anemia -- Megaloblastic Anemia -- Hematologic Manifestations of Systemic Illness -- Bone Marrow Failure -- Hemolytic Anemia Due to Membrane and Enzyme Defects -- Hemoglobinopathies -- Extracorpuscular Hemolytic Disease -- Polycythemia -- Disorders of the White Blood Cells -- Disorders of Platelets -- Hemostatic Disorders -- Thrombotic Disorders -- Lymphadenopathy and Splenomegaly -- Lymphoproliferative Disorders, Myelodysplastic Syndromes and Myeloproliferative Disorders -- Leukemias -- Histiocytosis Syndromes -- Hodgkin's Disease -- Non-Hodgkin's Lymphoma -- Central Nervous System Malignancies -- Neuroblastoma -- Wilms Tumor -- Rhabdomyosarcoma and other Soft Tissue Sarcomas -- Malignant Bone Tumors -- Retinoblastoma -- Germ Cell Tumors -- Hepatic Tumors -- Hematopoietic Stem Cell Transplantation -- Management of Oncologic Emergencies -- Supportive Care of Patients with Cancer -- Evaluation, Investigations and Management of Late Effects of Childhood Cancer -- Psychosocial Aspects of Cancer for Children and their Families -- Appendix 1. Hematologic Reference Values -- Appendix 2. Biological Tumor Markers -- Appendix 3. Pharmacologic Properties of the Commonly Used Anticancer Drugs
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Nathan and Oski's hematology and oncology of infancy and childhood

https://libcat.nshealth.ca/en/permalink/provcat33225
[edited by] Stuart H. Orkin, David E. Fisher, A. Thomas Look, Samuel E. Lux, IV, David Ginsburg, David G. Nathan. (Eighth edition) --Philadelphia, PA: Elsevier Saunders , c2015.
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Orkin, Stuart H
Responsibility
[edited by] Stuart H. Orkin, David E. Fisher, A. Thomas Look, Samuel E. Lux, IV, David Ginsburg, David G. Nathan
Edition
Eighth edition
Alternate Title
Hematology and oncology of infancy and childhood
Former Title
Nathan and Oski's hematology of infancy and childhood
Oncology of infancy and childhood
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Date of Publication
c2015
Physical Description
1 online resource
ISBN
9780323291774 (electronic bk.)
9781455754144
Subjects (MeSH)
Hematologic Diseases
Neoplasms
Subjects (LCSH)
Pediatric hematology
Tumors in children
Hematologic Diseases
Neoplasms
Child
Infant
Notes
Preceded by: Nathan and Oski's hematology of infancy and childhood / edited by Stuart H. Orkin ... [et al.]. 7th ed. c2009; and, Oncology of infancy and childhood / [edited by] Stuart H. Orkin ... [et al.]. 1st ed. c2009.
Contents
Anatomy and physiology of hematopoiesis -- The neonatal erythrocyte and its disorders -- Immune hemolytic disease -- Neonatal jaundice and disorders of bilirubin metabolism -- Hemostasis in the newborn and infant -- Acquired aplastic anemia and pure red cell aplasia -- Inherited bone marrow failure syndromes -- Principles of bone marrow and stem cell transplantation -- Diagnostic approach to the anemic patient -- Megaloblastic anemia -- Disorders of iron and copper metabolism, the sideroblastic anemias, and lead toxicity -- Porphyrias -- Autoimmune hemolytic anemia -- Paroxysmal nocturnal hemoglobinuria -- Red cell membrane -- Disorders of the red cell membrane -- Pyruvate kinase deficiency and disorders of glycolysis -- Glucose-6-phosphate dehydrogenase deficiency -- Normal and abnormal hemoglobins -- Sickle cell disease -- Thalassemias -- Phagocyte system and disorders of granulopoiesis and granulocyte function -- Immune response -- Primary immunodeficiency diseases -- Lysosomal storage diseases -- Platelets and the vessel wall -- Blood coagulation -- Molecular basis of fibrinolysis -- Approach to the child with a suspected bleeding disorder -- Inherited platelet disorders -- Hemophilia and von Willebrand disease -- Rare hereditary coagulation factor abnormalities -- Inherited disorders of thrombosis and fibrinolysis -- Acquired platelet defects -- Acquired disorders of hemostasis -- Transfusion medicine -- Hematologic manifestations of systemic diseases -- Hematologic manifestations of systemic diseases in children of the developing world -- Origins and evolution of pediatric cancers -- Epidemiology of leukemia in childhood -- Informatics -- Genetic predisposition to cancer -- Genetics and epigenetics of childhood cancers -- Targeted therapies in oncology -- Cytogenetic and molecular pathology of pediatric cancer -- Cancer chemotherapy for pediatric patients -- Immunotherapy of cancer -- Pediatric radiation oncology -- Pediatric surgical oncology -- Acute lymphoblastic leukemia -- Pediatric myeloid leukemia, myelodysplasia, and myeloproliferative disease -- Infant leukemias -- Pediatric lymphoma -- Neuroblastoma -- Pediatric renal tumors -- Retinoblastoma -- Tumors of the brain and spinal cord -- Hepatoblastoma and other liver tumors in children -- Rhabdomyosarcoma -- Nonrhabdomyosarcoma soft tissue sarcomas and other soft tissue tumors -- Ewing sarcoma -- Osteosarcoma -- Pediatric germ cell tumors -- Histiocytoses -- Rare tumors of childhood -- Imaging in the evaluation and management of childhood cancer -- Infectious disease in the pediatric cancer patient -- Oncologic emergencies -- Nursing care of patients with childhood cancer -- Palliative care in pediatric oncology -- Symptom management in children with cancer -- Childhood cancer survivorship -- Psychosocial care of the child and family -- Ethical considerations in pediatric oncology clinical trials -- Reference values in infancy and childhood.
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Pediatric critical care medicine. Volume 3, Gastroenterological, endocrine, renal, hematologic, oncologic and immune systems

https://libcat.nshealth.ca/en/permalink/provcat33357
Derek S. Wheeler, Hector R. Wong, Thomas P. Shanley, editors. (Second edition) --London: Springer , c2014.
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The Editors and contributors of this book take seriously the statement that 'For all of the science inherent in the specialty of pediatric critical care medicine, there is still art in providing comfort and solace to our patients and their families. No technology will ever replace the compassion in the touch of a hand or the soothing words of a calm and gentle voice.' The four volumes of Pediatric Critical Care Medicine: Basic Science and Clinical Evidence, 2nd Edition detail the continued grow…
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Other Authors
Wheeler, Derek S
Wong, Hector R
Shanley, Thomas P
Responsibility
Derek S. Wheeler, Hector R. Wong, Thomas P. Shanley, editors
Edition
Second edition
Alternate Title
Gastroenterological, endocrine, renal, hematologic, oncologic and immune systems
Place of Publication
London
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xxiii, 622 pages)
ISBN
9781447164166 (electronic bk.)
9781447164159
Subjects (MeSH)
Critical Illness - therapy
Gastrointestinal Diseases - therapy
Endocrine System Diseases - therapy
Kidney Diseases - therapy
Hematologic Diseases - therapy
Neoplasms - therapy
Immune System Diseases - therapy
Subjects (LCSH)
Pediatric intensive care
Pediatric gastroenterology
Pediatric endocrinology
Pediatric nephrology
Tumors in children
Immunologic diseases in children
Abstract
The Editors and contributors of this book take seriously the statement that 'For all of the science inherent in the specialty of pediatric critical care medicine, there is still art in providing comfort and solace to our patients and their families. No technology will ever replace the compassion in the touch of a hand or the soothing words of a calm and gentle voice.' The four volumes of Pediatric Critical Care Medicine: Basic Science and Clinical Evidence, 2nd Edition detail the continued growth and evolution of the pediatric critical care medicine speciality. They reveal the technological innovations in monitoring and information management and gives witness to the rapid evolution and adoption of novel monitoring techniques, such as continuous venous oximetry and near-infrared spectroscopy. They also cover advances in molecular biology that have led to the era of personalized medicine with the ability to individualize treatment to the unique and specific needs of a patient. As such this volume and its three sister titles will be of immense value to all studying and practicing pediatric critical care medicine or those involved in the management of this group of patients.
Contents
Part I. The Gastrointestinal System in Critical Illness and Injury -- Gastrointestinal Bleeding -- Liver Failure in Infants and Children -- Acute Pancreatitis -- Abdominal Compartment Syndrome in Children -- Obesity in Critical Illness -- Nutrition in the PICU -- Part II. The Endocrine System in Critical Illness and Injury -- Diabetic Ketoacidosis -- Hyperglycemia, Dysglycemia and Glycemic Control in Pediatric Critical Care -- Hypoglycemia -- The Adrenal Glands in Critical Illness and Injury -- Thyroid and Growth Hormone Axes Alteration in the Critically Ill Child -- Part III. The Renal System in Critical Illness and Injury -- Applied Renal Physiology in the PICU -- Electrolyte Disorders in the PICU -- Acid-Base Disorders in the PICU -- Acute Kidney Injury -- Kidney Disorders in the PICU: Thrombotic Microangiopathies and Glomerulonephritis -- Kidney Pharmacology -- Renal Replacement Therapy -- Part IV. The Hematologic System in Critical Illness and Injury -- Transfusion Medicine -- Hematologic Emergencies in the PICU -- Coagulation Disorders in the PICU -- Therapeutic Apheresis in the Pediatric Intensive Care Unit -- Thromboembolic Disorders in the PICU -- Part V. Oncologic Disorders in the PICU -- Care of the Oncology Patient in the PICU -- Critical Illness as a Result of Anti-Neoplastic Therapy -- Hemophagocytic Lymphohistiocytosis Syndromes -- Hematopoietic Stem Cell Transplantation in the PICU -- Part VI. The Immune System in Critical Illness and Injury -- The Immune System in Critical Illness and Injury -- Primary and Secondary Immunodeficiencies -- Sepsis -- Thrombocytopenia-Associated Multiple Organ Failure Syndrome -- Toxic Shock Syndrome in Children -- Hospital-Acquired Infections and the Pediatric Intensive Care Unit -- Anaphylaxis -- Rheumatologic Disorders in the PICU -- Infectious Disease-Associated Syndromes in the PICU -- Life Threatening Tropical Infections.
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Pediatric germ cell tumors : biology, treatment, survivorship

https://libcat.nshealth.ca/en/permalink/provcat33761
A. Lindsay Frazier, James F. Amatruda, editors. --Heidelberg: Springer , c2014.
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Germ cell tumors are relatively rare compared with other malignancies, and compilations of knowledge that encompass the entire spectrum of the disease are lacking. This textbook, written by the foremost authorities in the field, rectifies the situation by discussing in depth a broad range of topics, including biology, epidemiology, pathology, treatment, and late effects. Bearing in mind that germ cell tumors are most prevalent in the adolescent and young adult age group, causes of disease and t…
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Frazier, A. Lindsay
Amatruda, James F
Responsibility
A. Lindsay Frazier, James F. Amatruda, editors
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xii, 135 pages)
Series Vol.
v. 1
Series Title
Pediatric oncology (Series)
ISBN
9783642389719 (electronic bk.)
9783642389702
Subjects (MeSH)
Neoplasms, Germ Cell and Embryonal
Subjects (LCSH)
Generative organs - Cancer
Tumors in children
Neoplasms, Germ Cell and Embryonal
Oncology
Pediatrics
Abstract
Germ cell tumors are relatively rare compared with other malignancies, and compilations of knowledge that encompass the entire spectrum of the disease are lacking. This textbook, written by the foremost authorities in the field, rectifies the situation by discussing in depth a broad range of topics, including biology, epidemiology, pathology, treatment, and late effects. Bearing in mind that germ cell tumors are most prevalent in the adolescent and young adult age group, causes of disease and treatment approaches in pediatric and adult patients are compared and contrasted. By spanning the entire life course, from prenatal origins of disease through to treatment in adults and late effects of treatment, the editors have produced a book that will be of interest to both pediatric and adult oncologists.
Contents
Biology of germ cell tumors -- Epidemiology of germ cell tumors -- Pathology of germ cell tumors -- Clinical treatment of extracranial pediatric germ cell tumors -- Management of disseminated germ cell tumor in adults -- Clinical treatment of adult women with ovarian germ cell tumors -- Ovarian and testicular sex cord-stromal tumors -- Late effects in testicular cancer survivors.
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Pediatric head and neck tumors : A-Z guide to presentation and multimodality management

https://libcat.nshealth.ca/en/permalink/provcat33989
Reza Rahbar, Carlos Rodriguez-Galindo, John G. Meara, Edward R. Smith, Antonio R. Perez-Atayde, editors. --New York: Springer , c2014.
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Other Authors
Rahbar, Reza
Responsibility
Reza Rahbar, Carlos Rodriguez-Galindo, John G. Meara, Edward R. Smith, Antonio R. Perez-Atayde, editors
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xiii, 389 pages)
ISBN
9781461487555 (electronic bk.)
9781461487548
Subjects (MeSH)
Head and Neck Neoplasms - therapy
Subjects (LCSH)
Tumors in children
Head - Tumors
Neck - Tumors
Contents
Part I. Evaluation and Management -- 1. Imaging -- 2. Reconstructive Surgery -- 3. Chemotherapy -- 4. Radiotherapy -- 5. Interventional Radiology -- 6. Sentinel Lymph Node Biopsy -- Part II. Disease Specific -- 7. Arteriovenous Malformations: Extracranial -- 8. Arteriovenous Malformations: Intracranial -- 9. Capillary Malformations -- 10. Carcinoma/Undifferentiated Tumor -- 11. Chiari Malformation -- 12. Cholesteatoma -- 13. Craniopharyngioma -- 14. Dermoid: Head and Neck -- 15. Dermoid: Nasal -- 16. Encephaloceles -- 17. Esthesioneuroblastoma -- 18. Fibrous Dysplasia -- 19. Foregut Duplication Cysts -- 20. Germ Cell Tumors/Teratoma -- 21. Giant Cell Tumor -- 22. Nasal Glioma -- 23. Hamartomas -- 24. Hemangiomas -- 25. Juvenile Nasopharyngeal Angiofibroma -- 26. Langerhans Cell Histiocytosis -- 27. Leukemia and Lymphoma -- 28. Lymphatic Malformations -- 29. Melanoma -- 30. Nasopharyngeal Carcinoma -- 31. Neuroblastoma -- 32. Odontogenic Cysts -- 33. Odontogenic Tumors -- 34. Parathyroid Tumors -- 35. Pilomatrixoma -- 36. Pituitary Region Tumors -- 37. Retinoblastoma -- 38. Rhabdomyoma -- 39. Salivary Gland Tumors -- 40. Sarcoma: Bony Lesion -- 41. Sarcoma: Non-Rhabdomyosarcoma Soft Tissue Sarcomas -- 42. Sarcoma: Rhabdomyosarcoma -- 43. Thyroglossal Duct Cysts -- 44. Thyroid Tumors -- 45. Venous Malformations.
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Pediatric hematology-oncology in countries with limited resources : a practical manual

https://libcat.nshealth.ca/en/permalink/provcat33686
Daniela Cristina Stefan, Carlos Rodriguez-Galindo, editors. --New York: Springer , c2014.
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Typically, manuals of pediatric hematology-oncology are written by specialists from high-income countries, and usually target an audience with a sub-specialist level of training, often assisted by cutting-edge diagnostic and treatment facilities. However, approximately 80% of new cases of cancer in children appear in mid- and low-income countries. Almost invariably, general practitioners or general pediatricians without special training in oncology will look after children with malignancies who…
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Other Authors
Stefan, Daniela Cristina
Rodriguez-Galindo, Carlos
Responsibility
Daniela Cristina Stefan, Carlos Rodriguez-Galindo, editors
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xvi, 415 pages)
ISBN
9781461438915 (electronic bk.)
9781461438908
Subjects (MeSH)
Developing Countries
Health Care Rationing
Health Resources
Neoplasms
Resource Allocation
Subjects (LCSH)
Tumors in children
Pediatric hematology
Hematology
Infant
Child
Adolescent
Public Health - economics
Oncology
Pediatrics
Abstract
Typically, manuals of pediatric hematology-oncology are written by specialists from high-income countries, and usually target an audience with a sub-specialist level of training, often assisted by cutting-edge diagnostic and treatment facilities. However, approximately 80% of new cases of cancer in children appear in mid- and low-income countries. Almost invariably, general practitioners or general pediatricians without special training in oncology will look after children with malignancies who enter the health care system in these countries. The diagnostic facilities are usually limited, as are the treatment options. The survival figures in these conditions are somewhere below 20%, while in high-income countries they are in the range of 80% for many childhood cancers. Pediatric Hematology-Oncology in Countries with Limited Resources is the only book of its kind to provide specific guidance applicable to limited resource settings and builds up from the foundation of general practitioner or general pediatrician competence. Written and edited by leaders in the field, this manual educates physicians on the essential components of the discipline, filtered through the experience of specialists from developing countries, with immediate applicability in the specific healthcare environment in these countries.
Contents
Childhood Cancer in Low-Income and Middle-Income Countries in the Twenty-First Century -- Cancer Registries and the Descriptive Epidemiology of Pediatric Cancer in Low -- and Middle-Income Countries -- The Role of International Organizations on Collaborationfor Global Pediatric Cancer Control -- The Role of Twinning Programs and Telemedicine in Pediatric Oncology -- Pediatric Cancer Units and Optimization of Resources -- Early Warning Signs of Cancer in Children/Models for Early Diagnosis -- Care and Prevention of Infection -- Nutritional Assessment and Intervention -- Oncologic Emergencies -- Essential Medicines and Pharmacy Services -- Palliative and Supportive Care -- Psycho-Social Aspects/Parent Support Groups -- Nursing Care of Children with Cancer -- Paediatric Radiotherapy -- Procedures in Pediatric Oncology: Practical Guidelines -- Acute Lymphoblastic Leukemia -- Acute Myeloid Leukemia -- Hodgkin Lymphoma -- Non-Hodgkin Lymphoma -- Retinoblastoma -- Soft Tissue Sarcomas -- Bone Tumors -- Neuroblastoma -- Nephroblastoma -- Paediatric Neuro-Oncology -- HIV and Malignancy in Children -- Hematopoietic Stem Cell Transplant.
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e-Book
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Pediatric oncology : a comprehensive guide

https://libcat.nshealth.ca/en/permalink/provcat33269
Paul Imbach, Thomas Kühne, Robert J. Arceci, editors. (Third edition) --Cham, Switzerland: Springer , c2014.
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This is the third edition of a well-received compendium of information and guidance on the diagnosis and management of the various oncological diseases that are encountered in children and adolescents.In the new edition a chapter on Rare Tumors was added. For each disease entity, fundamental facts are provided that will be relevant for a range of professionals - hospital physicians, specialist nurses, psycho-oncologists, physiotherapists, family doctors, and pediatricians. Compared with the fir…
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Imbach, Paul
Kühne, Thomas
Arceci, Robert
Responsibility
Paul Imbach, Thomas Kühne, Robert J. Arceci, editors
Edition
Third edition
Place of Publication
Cham, Switzerland
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xviii, 255 pages)
ISBN
9783319060101 (electronic bk.)
9783319060095
Subjects (MeSH)
Neoplasms
Subjects (LCSH)
Tumors in children
Abstract
This is the third edition of a well-received compendium of information and guidance on the diagnosis and management of the various oncological diseases that are encountered in children and adolescents.In the new edition a chapter on Rare Tumors was added. For each disease entity, fundamental facts are provided that will be relevant for a range of professionals - hospital physicians, specialist nurses, psycho-oncologists, physiotherapists, family doctors, and pediatricians. Compared with the first edition all chapters have been updated. Throughout, rapid orientation is ensured by the clear, consistent layout and the concise, lucid style. Pediatric Oncology: A Comprehensive Guide is an excellent, easy-to-use reference that belongs on the shelf of every practitioner who encounters or treats malignancies in the pediatric age group. Pediatric Oncology is teamwork! Fundamental facts for all those involved in diagnosis and management - even social worker, pedagogic teachers, religious care persons.
Contents
General Aspects of Childhood Leukemia -- Acute Lymphoblastic Leukemia -- Acute Myeloid Leukemia -- Myelodysplastic Syndrome -- Myeloproliferative Neoplasms -- Non-Hodgkin Lymphoma -- Hodgkin Disease -- Histiocytoses -- Brain Tumors -- Neuroblastoma -- Renal Tumors -- Soft Tissue Sarcomas -- Osteosarcoma -- Ewing Sarcoma Family of Tumors -- Retinoblastoma -- Germ Cell Tumors -- Hepatic Tumors -- Rare Tumors -- Emergencies in Pediatric Oncology -- Oncological Nursing Care -- Psychology and Psychosocial Issues in Children with Cancer.
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Publication Type
Outline
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