The Clinician's Vaccine Safety Resource Guide : Optimizing Prevention of Vaccine-Preventable Diseases Across the Lifespan
https://libcat.nshealth.ca/en/permalink/provcat42718
Matthew Z. Dudley, Daniel A. Salmon, Neal A. Halsey, Walter A. Orenstein, Rupali J. Limaye, Sean T. O'Leary, Saad B. Omer.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book provides clinicians and their staff with essential information on the vaccines that are recommended and not recommended for their patients, the diseases these vaccines prevent, and a broad range of potential vaccine safety issues that may be brought up by their patients. Each topic, from specific vaccines to safety concerns, is covered succinctly, based upon systematic reviews of the scientific literature, with talking points to be used with patients. The organization of the informati…
- Available Online
- View e-Book
- Author
- Dudley, Matthew Z.
- Other Authors
- Salmon, Daniel A.
- Halsey, Neal A.
- Orenstein, Walter A.
- Limaye, Rupali J.
- O'Leary, Sean T.
- Omer, Saad B.
- Responsibility
- Matthew Z. Dudley, Daniel A. Salmon, Neal A. Halsey, Walter A. Orenstein, Rupali J. Limaye, Sean T. O'Leary, Saad B. Omer
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xxvi, 392 p.) : 13 illus. in color
- ISBN
- 9783319946948
- 9783319946931 (print ed.)
- 9783319946955 (print ed.)
- Subjects (MeSH)
- Vaccination
- Vaccines - adverse effects
- Vaccines - therapeutic use
- Specialty
- Vaccinology
- Abstract
- This book provides clinicians and their staff with essential information on the vaccines that are recommended and not recommended for their patients, the diseases these vaccines prevent, and a broad range of potential vaccine safety issues that may be brought up by their patients. Each topic, from specific vaccines to safety concerns, is covered succinctly, based upon systematic reviews of the scientific literature, with talking points to be used with patients. The organization of the information makes it easy to reference specific topics and quickly find pertinent information, with the most practical details (such as recommendations and causality conclusions) highlighted at the very beginning of the respective sections. There are also sections outlining the vaccine safety system and evidence-based strategies for how to talk with patients about vaccines. This book aims to improve the efficiency and effectiveness of clinical vaccine discussions with patients, leading to more informed patients and timely vaccination. This is an ideal resource for all clinicians administering vaccines and their healthcare teams.
- Contents
- Part I: Introduction -- Introduction -- How to Talk with Patients About Vaccines -- Monitoring Vaccine Safety -- Vaccines and Pregnancy -- Vaccines and Breastfeeding -- Part II: Vaccine and Vaccine-Preventable Disease Information Summaries -- Vaccine and Vaccine-Preventable Disease Information Summaries -- Haemophilus influenzae type b (Hib) -- Hepatitis A -- Hepatitis B -- Human Papillomavirus (HPV) -- Influenza -- Measles, Mumps and Rubella -- Meningococcal -- Pneumococcal -- Polio -- Rotavirus -- Tetanus, Diphtheria and Pertussis -- Varicella and Herpes Zoster -- Part III: Potential Adverse Events Following Immunization -- Potential Adverse Events Following Immunization: Summaries of the Evidence -- Do Combination Vaccines or Simultaneous Vaccination Increase the Risk of Adverse Events? -- Do Vaccine Ingredients Cause Adverse Events? -- Do Vaccines Cause Acute Disseminated Encephalomyelitis (ADEM)? -- Do Vaccines Cause Arthralgia or Arthritis? -- Do Vaccines Cause Asthma? -- Do Vaccines Cause Ataxia? -- Do Vaccines Cause Autism? -- Do Vaccines Cause Bell's Palsy? -- Do Vaccines Cause Brachial Neuritis? -- Do Vaccines Cause Chronic Inflammatory Disseminated Polyneuropathy? -- Do Vaccines Cause Complex Regional Pain Syndrome? -- Do Vaccines Cause Deltoid Bursitis? -- Do Vaccines Cause Diabetes? -- Do Vaccines Cause Disseminated Varicella Infection? -- Do Vaccines Cause Erythema Nodosum? -- Do Vaccines Cause Fibromyalgia or Chronic Fatigue Syndrome? -- Do Vaccines Cause Guillain-Barré Syndrome? -- Do Vaccines Cause Hearing Loss? -- Do Vaccines Cause Hepatitis? -- Do Vaccines Cause Herpes Zoster? -- Do Vaccines Cause Hypersensitivity Reactions (e.g. anaphylaxis, hives)? -- Do Vaccines Cause Immune Thrombocytopenic Purpura? -- Do Vaccines Cause Meningitis or Encephalitis/Encephalopathy? -- Do Vaccines Cause Multiple Sclerosis? -- Do Vaccines Cause Myocardial Infarction or Stroke? -- Do Vaccines Cause Myocarditis or Myocardopathy/Cardiomyopathy? -- Do Vaccines Cause Narcolepsy? -- Do Vaccines Cause Oculorespiratory Syndrome? -- Do Vaccines Cause Opsoclonus Myoclonus Syndrome? -- Do Vaccines Cause Optic Neuritis or Neuromyelitis Optica? -- Do Vaccines Cause Primary Ovarian Insufficiency? -- Do Vaccines Cause Seizures? -- Do Vaccines Cause Serum Sickness? -- Do Vaccines Cause Small Fiber Neuropathy? -- Do Vaccines Cause Spontaneous Abortion? -- Do Vaccines Cause Sudden Infant Death Syndrome (SIDS)? -- Do Vaccines Cause Syncope? -- Do Vaccines Cause Systemic Lupus Erythematosus? -- Do Vaccines Cause Transverse Myelitis? -- Do Vaccines Cause Vasculitis or Polyarteritis Nodosa?
- Format
- e-Book
- Location
- Online
Oncoimmunology : A Practical Guide for Cancer Immunotherapy
https://libcat.nshealth.ca/en/permalink/provcat42777
Laurence Zitvogel, Guido Kroemer, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare …
- Available Online
- View e-Book
- Other Authors
- Zitvogel, Laurence
- Kroemer, Guido
- Responsibility
- Laurence Zitvogel, Guido Kroemer, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (x, 724 p.) : 133 illus., 131 illus. in color
- ISBN
- 9783319624310
- 9783319624303 (print ed.)
- 9783319624327 (print ed.)
- 9783319873107 (print ed.)
- Subjects (MeSH)
- Cancer Vaccines
- Immunotherapy
- Neoplasms - immunology
- Neoplasms - therapy
- Specialty
- Medical Oncology
- Vaccinology
- Abstract
- In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals. Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field.
- Contents
- 1. Principles of Oncoimmunology -- Part I. Fundamentals in I-O -- 2. The Human Tumor Microenvironment -- 3. CD8+ T Cells in Immunotherapy, Radiotherapy, and Chemotherapy -- 4. Mutant Epitopes in Cancer -- 5. The Secrets of T Cell Polarization -- 6. Regulatory T Cells: Their Role, Mechanism of Action, and Impact on Cancer -- 7. Purinergic Receptors: Novel Targets for Cancer Immunotherapy -- 8. Plasmacytoid DC/Regulatory T Cell Interactions at the Center of an Immunosuppressive Network in Breast and Ovarian Tumors -- 9. Cancer Immunosurveillance by Natural Killer Cells and Other Innate Lymphoid Cells -- 10. Biology of Myeloid-Derived Suppressor Cells -- 11. Effect of Pharmaceutical Compounds on Myeloid-Derived Suppressor Cells -- 12. Immunogenic Stress and Death of Cancer Cells in Natural and Therapy-Induced Immunosurveillance -- 13. Genetics and Immunology: Tumor-Specific Genetic Alterations as a Target for Immune Modulating Therapies -- Part II. Breakthrough Status -- 14. Peptide-Based Therapeutic Cancer Vaccines -- 15. Cancer Vaccines for HPV Malignancies -- 16. NK Cell-Based Therapies -- 17. IDO/TDO Inhibition in Cancer -- Part III FDA-EMA Approval of I-O -- 18. Tumor-Targeted Antibodies -- 19. PD1 Checkpoint Blockade in Melanoma: From Monotherapy to Combination Therapies -- 20. Immune Checkpoint Inhibition in Lung Cancer -- 21. PD-1 Blockade in Renal Cell Carcinoma -- 22. BCG and Anti-PDL-1 Ab in Bladder Cancers -- 23. PD-L1 and Other Immunological Diagnosis Tools -- 24. Oncolytic Viruses: T-VEC and Others -- Part IV. Developing Fields -- 25. Innate Immune Receptors in the Regulation of Tumor Immunity -- 26. Co-stimulation Agonists via CD137, OX40, GITR, and CD27 for Immunotherapy of Cancer -- 27. The Impact of the Intestinal Microbiota in Therapeutic Responses Against Cancer -- 28. Local Immunotherapies of Cancer -- 29. Strategies to Reduce Intratumoral Regulatory T Cells -- 30. Synergy Between Radiotherapy and Immunotherapy -- 31. Predictors of Response to Immune Checkpoint Blockade -- Part V. Changes in Clinical Practice -- 32. Immune Therapies in Phase 1 Trials -- 33. Side Effects of Cancer Immunotherapy with Checkpoint Inhibitors -- 34. Melanoma: Immunotherapy in Advanced Melanoma and in the Adjuvant Setting -- 35. Immunotherapy for Prostate Cancer: An Evolving Landscape -- 36. Challenges of Oncoimmunology for Ovarian and Breast Cancers -- 37. Challenges in Colorectal Cancer: From Vaccines to Macrophage Repolarization -- 38. Current Status of Immuno-Oncology in Hematologic Cancers -- 39. Immunotherapy of Gliomas -- 40. Assessing T Cell Receptor Affinity and Avidity Against Tumor Antigens -- 41. Immune Monitoring of Blood and Tumor Microenvironment -- 42. Toward Engineered Cells as Transformational and Broadly Available Medicines for the Treatment of Cancer -- Part VI. Concluding Remarks -- 43. Concluding Remarks.
- Format
- e-Book
- Location
- Online
Plotkin's vaccines
https://libcat.nshealth.ca/en/permalink/provcat32092
edited by Stanley A. Plotkin, Walter A. Orenstein, Paul A. Offit.
(7th ed.)
--Philadelphia, PA:
Elsevier
, c2018.
- Available Online
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- Access
- Registration required for PDF access.
- Location
- Online
- Available Online
- View e-Book
- Other Authors
- Plotkin, Stanley A
- Orenstein, Walter A
- Offit, Paul A
- Responsibility
- edited by Stanley A. Plotkin, Walter A. Orenstein, Paul A. Offit
- Edition
- 7th ed.
- Alternate Title
- Vaccines
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- c2018
- Physical Description
- 1 online resource
- ISBN
- 9780323357616
- Subjects (MeSH)
- Immunization Programs
- Vaccination
- Vaccines
- Subjects (LCSH)
- Vaccines
- Immunization Programs
- Specialty
- Vaccinology
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Vaccines : A Clinical Overview and Practical Guide
https://libcat.nshealth.ca/en/permalink/provcat46400
Joseph Domachowske, Manika Suryadevara, editors.
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Location
- Online
Part 1 begins with a review of the human response to infection including key definitions and general concepts important in the field of vaccinology. Next, detailed chapters on currently available strategies that provide passive and active immune protection against infectious diseases are presented, including descriptions for how these biologic products are produced. Given the complexity of the manufacturing processes used in vaccine production and the frequency with which questions arise regard…
- Available Online
- View e-Book
- Other Authors
- Domachowske, Joseph
- Suryadevara, Manika
- Responsibility
- Joseph Domachowske, Manika Suryadevara, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (xv, 494 p.)
- ISBN
- 9783030584146
- 9783030584139 (Print ed.)
- 9783030584153 (Print ed.)
- 9783030584160 (Print ed.)
- Subjects (MeSH)
- Communicable Diseases - prevention & control
- Vaccination
- Vaccines
- Specialty
- Vaccinology
- Abstract
- Part 1 begins with a review of the human response to infection including key definitions and general concepts important in the field of vaccinology. Next, detailed chapters on currently available strategies that provide passive and active immune protection against infectious diseases are presented, including descriptions for how these biologic products are produced. Given the complexity of the manufacturing processes used in vaccine production and the frequency with which questions arise regarding the presence of various additives and excipients found in vaccines, a full chapter has been dedicated to the topic. Part 1 concludes with a chapter outlining the regulatory processes and timelines needed for the development and testing of new vaccine candidates. Part 2 of the book includes separate chapters on each of the 35 infections that are currently vaccine preventable. The chapters are presented in alphabetical order according to disease. The reader will find that certain terms and concepts important to the study of vaccines appear in many or even all of the chapters. Familiarity with the definition of several of these terms as they are used in vaccinology and in human clinical vaccine trials is key to developing an authoritative understanding of the field so they are introduced first here.
- Contents
- Part I. The Basics of Preventing Infection Through Immunization -- The Immune Response to Infection -- Passive Immunization -- Active Immunization -- Vaccine Additives and Excipients -- The Process and Timeline to Develop a New Vaccine -- Part II. Vaccine Preventable Infections -- Adenovirus -- Anthrax -- Cholera -- Dengue -- Diphtheria -- Ebola -- Haemophilus Influenzae Type B -- Hepatitis A -- Hepatitis B -- Human Papillomavirus -- Influenza -- Japanese Encephalitis -- Measles -- Meningococcus -- Mumps -- Pertussis -- Plague -- Pneumococcus -- Polio -- Rabies -- Rotavirus -- Rubella -- Smallpox -- Tetanus -- Tickborne Encephalitis -- Tuberculosis -- Typhoid Fever -- Varicella and Shingles -- Yellow Fever -- Combination Vaccines -- Part III. Maintaining a Culture of Vaccine Confidence -- Vaccine Preventable Disease Outbreaks -- Vaccine Mandates -- Vaccine Confidence and Vaccine Hesitancy -- Communicating with Parents About Vaccines.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Vaccines : Are they Worth a Shot?
https://libcat.nshealth.ca/en/permalink/provcat43407
Andrea Grignolio.
--Cham:
Copernicus Books
, c2018.
- Available Online
- View e-Book
- Location
- Online
The dangerous decline in vaccinations in many developed countries is at the heart of a lively debate that confirms how important the subject is today. Vaccinations are among mankind's most important scientific discoveries, yet they continue to be viewed with suspicion by part of the public--the victims of disinformation campaigns, instrumentalization and unfounded fears. There is, however, also an evolutionary explanation for these irrational beliefs, and countering the growing social oppositio…
- Available Online
- View e-Book
- Author
- Grignolio, Andrea
- Responsibility
- Andrea Grignolio
- Place of Publication
- Cham
- Publisher
- Copernicus Books
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xii, 181 p.) : 5 illus., 3 illus. in color
- ISBN
- 9783319681061
- 9783319681054 (print ed.)
- 9783319681078 (print ed.)
- Subjects (MeSH)
- Anti-Vaccination Movement
- Vaccination
- Dissent and Disputes
- Specialty
- Public Health
- Vaccinology
- Abstract
- The dangerous decline in vaccinations in many developed countries is at the heart of a lively debate that confirms how important the subject is today. Vaccinations are among mankind's most important scientific discoveries, yet they continue to be viewed with suspicion by part of the public--the victims of disinformation campaigns, instrumentalization and unfounded fears. There is, however, also an evolutionary explanation for these irrational beliefs, and countering the growing social opposition will be extremely difficult without grasping it. This book, which sheds new light on the safety and importance of vaccinations, is intended both for parents and those readers who want to understand the role of vaccinations in contemporary society, where the ease of access to knowledge is both a great opportunity and a great responsibility. The chapters follow a historical progression and conclude with a discussion of the most recent cognitive theories on how to overcome this opposition to vaccinations.
- Contents
- Who is afraid of vaccines? -- A brief history of anti-vaccination movements -- The accusations against vaccinations on the Internet: autism, mercury and immunological overload -- How to unmask the anti-vaccination "experts" -- The past, present, and future of vaccines -- Conclusions.
- Format
- e-Book
- Publication Type
- Popular Works
- Location
- Online
