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Acute Exacerbation of Chronic Hepatitis B : Volume 1. Definition, Research Technology, Virology, Genetics and Immunology

https://libcat.nshealth.ca/en/permalink/provcat44504
Qin Ning, editor. --Dordrecht: Springer , c2019.
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This book assembles recent achievements in both basic research and clinical management in the field of hepatology, virology and immunology. It provides up-to-date information for clinicians who can apply the relevant knowledge to their daily clinical practice and for researchers who are interested in clinically orientated studies. The updated and detailed technology, state-of–the-art treatment strategies provided in this book serve as references for clinicians and resident physicians in the dai…
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Other Authors
Ning, Qin
Responsibility
Qin Ning, editor
Place of Publication
Dordrecht
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (xxiii, 369 p.) : 55 illus., 44 illus. in color
ISBN
9789402416060
9789402416046 (Print ed.)
9789402416053 (Print ed.)
Subjects (MeSH)
Disease Progression
Hepatitis B, Chronic - genetics
Hepatitis B, Chronic - immunology
Hepatitis B, Chronic - virology
Specialty
Gastroenterology
Virology
Abstract
This book assembles recent achievements in both basic research and clinical management in the field of hepatology, virology and immunology. It provides up-to-date information for clinicians who can apply the relevant knowledge to their daily clinical practice and for researchers who are interested in clinically orientated studies. The updated and detailed technology, state-of–the-art treatment strategies provided in this book serve as references for clinicians and resident physicians in the daily management of ACLF. The rationality and strategies for basic research as well as patient management in this book can also be a valuable reference for other fatal and end stage liver diseases than HBV induced ACLF. This volume 1 has 6 chapters and focuses on the definition, research technology, virology, genetics, and immunology.
Contents
1. Introduction to Acute Exacerbation of Chronic Hepatitis B (AECHB) -- 2. Research Methods and Techniques for Acute Exacerbation of Chronic Hepatitis B -- 3. Virological Factors Involved in AECHB -- 4. Host Genetic Characters of Acute Exacerbation of Chronic Hepatitis B (AECHB) -- 5. Immunological Features of AECHB -- 6. Other Precipitating Factors for AECHB.
Format
e-Book
Location
Online
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Acute Exacerbation of Chronic Hepatitis B : Volume 2. Diagnosis and Management

https://libcat.nshealth.ca/en/permalink/provcat44403
Qin Ning, editor. --Dordrecht: Springer , c2019.
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Online
This book assembles recent achievements in both basic research and clinical management in the field of hepatology, virology and immunology. It provides up-to-date information for clinicians who can apply the relevant knowledge to their daily clinical practice and for researchers who are interested in clinically orientated studies. The updated and detailed technology, state-of–the-art treatment strategies provided in this book serve as references for clinicians and resident physicians in the dai…
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Other Authors
Ning, Qin
Responsibility
Qin Ning, editor
Place of Publication
Dordrecht
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (xxiii, 497 p.) : 41 illus., 31 illus. in color
ISBN
9789402416039
9789402416015 (Print ed.)
9789402416022 (Print ed.)
Subjects (MeSH)
Disease Progression
Hepatitis B, Chronic - diagnosis
Hepatitis B, Chronic - therapy
Liver Failure - therapy
Specialty
Gastroenterology
Virology
Abstract
This book assembles recent achievements in both basic research and clinical management in the field of hepatology, virology and immunology. It provides up-to-date information for clinicians who can apply the relevant knowledge to their daily clinical practice and for researchers who are interested in clinically orientated studies. The updated and detailed technology, state-of–the-art treatment strategies provided in this book serve as references for clinicians and resident physicians in the daily management of ACLF. The rationality and strategies for basic research as well as patient management in this book can also be a valuable reference for other fatal and end stage liver diseases than HBV induced ACLF. This Volume 2 has 6 chapters and focuses on its diagnosis and management.
Contents
1. Clinical Manifestations and Laboratory Tests of AECHB and Severe Hepatitis (Liver Failure) -- 2. Main Complications of AECHB and Severe Hepatitis B (Liver Failure) -- 3. Early Prognostic Predictive System of AECHB and the Diagnosis of Severe Hepatitis B (Liver Failure) -- 4. Treatment of AECHB and Severe Hepatitis (Liver Failure) -- 5. Antiviral Therapy for AECHB and Severe Hepatitis B (Liver Failure) -- 6. Prognosis, Prevention and Research Prospects of Progression to Severe Hepatitis B (Liver Failure).
Format
e-Book
Location
Online
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Adherence to Antiretroviral Therapy among Perinatal Women in Guyana

https://libcat.nshealth.ca/en/permalink/provcat47079
Debbie Vitalis. Palgrave Macmillan , 2021.
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Online
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Responsibility
Debbie Vitalis
Publisher
Palgrave Macmillan
Date of Publication
2021
Physical Description
1 online resource (xxxiv, 267 pages) : illustrations
ISBN
9789811539749
Other Subjects
Guyana
Specialty
Infectious Disease Medicine
Perinatology
Virology
Format
e-Book
Location
Online
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The African-American guide to hepatitis C

https://libcat.nshealth.ca/en/permalink/provcat23101
Daniel, Samuel J. --Chicago, IL: Hilton Publishing Co. , 2005.
Call Number
WC 536 D184a 2005
Location
Halifax Infirmary
Call Number
WC 536 D184a 2005
Author
Daniel, Samuel J
Other Authors
Markovits, Temima
Williams, Vernon A
Place of Publication
Chicago, IL
Publisher
Hilton Publishing Co.
Date of Publication
2005
Physical Description
171 p.
ISBN
0971606722
Subjects (MeSH)
Hepatitis C - popular works
African Americans
Specialty
Gastroenterology
Virology
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Antibiotic Policies : Controlling Hospital Acquired Infection

https://libcat.nshealth.ca/en/permalink/provcat30848
Ian M. Gould, Jos W.M. van der Meer, editors. --New York, NY: Springer , c2012.
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Hospitals worldwide are currently suffering an epidemic of infections, generated in and spreading in those instituitions whose very "raison d'etre" is to protect and improve the health of their patients. This paradox comes at a time of possibly unprecedented investment in preventative measures (infection control). To better control these infections, however, we need to understand their causes, many of which are related, paradoxically, to the success of antibiotic therapy. It is possible that th…
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Gould, Ian M
Meer, Jos W.M van der
Responsibility
Ian M. Gould, Jos W.M. van der Meer, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xiii, 209 p. : 6 ill.)
ISBN
9781441917348
Subjects (MeSH)
Infection Control - organization & administration
Anti-Bacterial Agents
Bacterial Infections - drug therapy
Drug Resistance, Microbial
Subjects (LCSH)
Medical virology
Microbiology
Infectious diseases
Abstract
Hospitals worldwide are currently suffering an epidemic of infections, generated in and spreading in those instituitions whose very "raison d'etre" is to protect and improve the health of their patients. This paradox comes at a time of possibly unprecedented investment in preventative measures (infection control). To better control these infections, however, we need to understand their causes, many of which are related, paradoxically, to the success of antibiotic therapy. It is possible that the golden era of antibiotics led subconsciously to a loss of emphasis on the importance of hygiene in the control of HAI. Moreover, the majority of HAIs are due to multiply antibiotic resistant bacteria whose emergence has been hastened by over-enthusiastic antibiotic prescribing. Accumulating evidence also suggests that antibiotics not only select for resistance but can actually increase the numbers of HAIs and even their virulence. This comprehensive compilation, written by eminent international researchers, explores these hypothesis in the context of recent epidemiology and evidence for the success of various antibiotic stewardship measures in controlling and even reversing resistance. It contains chapters by acclaimed authors on all the major causes of HAI, including MRSA, VRE, Clostridium difficile and multi resistant gram negative infections which are increasingly pan-resistant and untreatable; the nearest thing we have yet experienced to a "Doomsday bug". This book is an excellent source of information for students, researchers and practitioners in infection control, hospital epidemiology, antimicrobial prescribing and microbiology.
Contents
Healthcare Associated Infections: The Size of the Problem -- The Antibiotic Paradox -- The Epidemiology of Pan/Extreme Drug Resistance -- Hospital Antibiotic Stewardship to Control Resistance - how should it be done? -- Controlling Clostridium difficile infection and the role of antibiotic stewardship -- The control of MRSA -- The role of antibiotic policies in controlling VRE -- The control of ESBL producing bacteria -- Controlling Hospital-Acquired Infection due to Carbapenem-Resistant Enterobacteriaceae (CRE) -- Control of multi-drug resistant Acinetobacter infections -- The control of multidrug-resistant Pseudomonas: Insights into epidemiology and management -- Multidrug-resistant infections in low-resource health care settings -- Germ Shed Management in the United States -- Required actions.
Format
e-Book
Location
Online
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Autoimmune Hepatitis : A Guide for Practicing Clinicians

https://libcat.nshealth.ca/en/permalink/provcat31001
Gideon M. Hirschfield, E. Jenny Heathcote, editors. --New York, NY: Springer , c2012.
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With a focus on practical patient related issues, Autoimmune Hepatitis: A Guide for Practicing Clinicians serves as a useful practical, and much needed, resource for all those physicians presented with managing patients diagnosed with autoimmune hepatitis, both acutely and over the long term. It provides a basis for clinicians to understand the etiology of the disease, as well as special circumstances where management dilemmas often arise. Emphasis is given to providing management advice of imm…
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Hirschfield, Gideon M
Heathcote, E. Jenny
Responsibility
Gideon M. Hirschfield, E. Jenny Heathcote, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (x, 243 p. : 16 ill., 13 ill. in color)
Series Title
Clinical gastroenterology
ISBN
9781607615699
Subjects (MeSH)
Hepatitis, Autoimmune
Subjects (LCSH)
Internal medicine
Hepatology
Clinical medicine
Specialty
Allergy and Immunology
Gastroenterology
Virology
Abstract
With a focus on practical patient related issues, Autoimmune Hepatitis: A Guide for Practicing Clinicians serves as a useful practical, and much needed, resource for all those physicians presented with managing patients diagnosed with autoimmune hepatitis, both acutely and over the long term. It provides a basis for clinicians to understand the etiology of the disease, as well as special circumstances where management dilemmas often arise. Emphasis is given to providing management advice of immediate use to clinicians, something not presently offered by other larger general texts. The chapters are written by those with an expertise and training in this field and include the most up to date information. This book is of great value to Gastroenterologists, Hepatologists, and Internists at all levels who see patients presenting with autoimmune hepatitis.
Contents
Pathogenesis of autoimmune hepatitis -- Clinical presentation -- Confirmation of the diagnosis: interpreting the serology -- Mimics of autoimmune hepatitis: drug induced and immune mediated liver disease -- When and how to treat the adult patient -- When and how to treat the pediatric patient -- Strategies for treatment nonresponders: second-line therapies and novel approaches -- Liver transplantation for autoimmune hepatitis -- Autoimmune hepatitis and pregnancy -- Treatment side effects and associated autoimmune diseases -- Managing the patient with features of overlapping autoimmune liver disease -- Autoimmune hepatitis: a look toward the future.
Format
e-Book
Location
Online
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Cancer Associated Viruses

https://libcat.nshealth.ca/en/permalink/provcat30906
Erle S. Robertson, editor. --New York, NY: Springer , c2012.
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This volume constitutes a comprehensive review of the different aspects of tumor virology 100 years after the discovery of the Rous-sarcoma virus. Its aim is to bring a greater focus on the contributions of viral agents to the development of cancer, and to create an up to date compendium of the general molecular biology of these viruses, átheir gene products, and targeted functions. The content of the book comprises general chapters which tie into the many aspects of cancer-related viruses and …
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Robertson, Erle S
Responsibility
Erle S. Robertson, editor
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xxiii, 866 p. : 125 ill., 68 ill. in color)
Series Title
Current cancer research
ISBN
9781461400165
Subjects (MeSH)
Oncogenic Viruses
Tumor Virus Infections
Subjects (LCSH)
Oncology
Virology
Abstract
This volume constitutes a comprehensive review of the different aspects of tumor virology 100 years after the discovery of the Rous-sarcoma virus. Its aim is to bring a greater focus on the contributions of viral agents to the development of cancer, and to create an up to date compendium of the general molecular biology of these viruses, átheir gene products, and targeted functions. The content of the book comprises general chapters which tie into the many aspects of cancer-related viruses and how they contribute to cell proliferation, the genes that are responsible for driving these cancers, and their mechanisms of transmission. The book also reviews the current knowledge on the molecular biology of large DNA viruses and describes the many different pathways through which they contribute to cell proliferation. Papilloma viruses and Adenoviruses, well known to be associated with invasive carcinomas, and hepatitis viruses, HTLV and retroviruses are also discussed. This volume is dedicated to Baruch Blumberg, an outstanding scientist and recipient of the Nobel Prize for the discovery of the hepatitis B virus, who was also the author of one of the chapters.
Contents
In Memoriam -- Preface -- 1. Peyton Rous: A centennial tribute to the founding father of cancer virology -- 2. Viruses and Cancer: A Historical Perspective – HBV and Prevention of a Cancer -- 3. Virus Mediated Cell Proliferation -- 4. Viral Encoded Genes and Cancer -- 5. Oncogenic Viruses and Cancer Transmission -- 6. DNA Viruses and Cancer: Taking a Broader Look -- 7. Herpesviruses and Cancer -- 8. Lymphocryptoviruses: EBV and its role in human cancer -- 9. Nonhuman Primate Gamma-herpesviruses and Their Role in Cancer -- 10. Rhadinoviruses: KSHV and associated malignancies -- 11. Retroperitoneal Fibromatosis Herpesvirus and Kaposi’s Sarcoma-Like Tumors in Macaques -- 12. Murine Gammaherpesvirus-Associated Tumorigenesis -- 13. Marek’s Disease Virus-Induced T-Cell Lymphomas -- 14. Polyoma Viruses and Cancer -- 15. Polyomavirus SV40: Model Infectious Agent of Cancer -- 16. BK Polyomavirus and Transformation -- 17. Polyomavirus JC and Human Cancer: Possible Role of Stem Cells in Pathogenesis -- 18. Merkel Cell Polyomavirus -- 19. Human Papillomaviruses and Cancer -- 20. Tumorigenesis by Adenovirus Type 12 E1A -- 21. Overview of Hepatitis Viruses and Cancer -- 22. Hepadnaviruses and Hepatocellular Carcinoma -- 23. Hepatitis C Virus and Hepatocellular Carcinoma -- 24. Human and Animal Retroviruses: HIV-1 Infection Is a Risk Factor for Malignancy -- 25. HTLV-1 and Oncogenesis -- 26. Human T-Cell Leukemia Virus Type 2 (HTLV-2) Biology and Pathogenesis -- 27. Mechanisms of Oncogenesis by Avian and Murine Retroviruses -- 28. Rous Sarcoma Virus: Contributions of a Chicken Virus to Tumor Biology, Human Cancer Therapeutics, and Retrovirology -- 29. Mouse Mammary Tumor Virus and Cancer -- 30. Jaagsiekte Sheep Retrovirus and Lung Cancer -- 31. Small RNAs and Their Role in Herpesvirus-Mediated Cancers -- 32. Viral Malignancies in HIV-Associated Immune Deficiency -- Index.
Format
e-Book
Location
Online
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Chronic Hepatitis C Virus : Advances in Treatment, Promise for the Future

https://libcat.nshealth.ca/en/permalink/provcat30939
Mitchell L. Shiffman, editor. --New York, NY: Springer , c2012.
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Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade wi…
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Other Authors
Shiffman, Mitchell L
Responsibility
Mitchell L. Shiffman, editor
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xvi, 332 p. : 53 ill., 33 ill. in color)
ISBN
9781461411925
Subjects (MeSH)
Antiviral Agents - therapeutic use
Hepacivirus - pathogenicity
Hepatitis C, Chronic - therapy
Liver Transplantation
Specialty
Gastroenterology
Virology
Abstract
Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade with interferon based therapy. Separate chapters on response guided therapy and how to manage the adverse events associated with these medications provide the physician with the concepts required to more effectively treat chronic HCV now and in the future. As the genetics of virologic response have recently been elucidated, a chapter is devoted to helping the clinician understand how genes that modulate disease processes and their treatment are identified and utilized in clinical care. Section 3 deals with the future of HCV treatment and specific inhibitors of HCV. Specific chapters explain how targets for drugs are identified and how drugs are then developed and tested; how mutations of HCV develop and how anti-viral agents will affect this process; the most up to date data regarding the treatment of chronic HCV with peginterferon, ribavirin and anti-viral agents; and the potential to treat chronic HCV with just oral anti-viral agents and without peginterferon and ribavirin in the future. The final section of this book covers issues related to liver transplantation in patients with chronic HCV. Separate chapters review the natural history of chronic HCV in liver transplant recipients and the impact of utilizing HCV positive donors. The volume concludes with chapters that cover the treatment of chronic HCV both prior to and after liver transplantation with potent anti-viral agents. Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future is a valuable resource for all physicians caring for patients with chronic HCV.
Contents
Epidemiology of Chronic HCV -- Acute HCV -- Assessing the Progression of Chronic HCV to Cirrhosis -- Chronic HCV and Steatosis -- Chronic HCV and Hepatocellular Carcinoma -- Extrahepatic Manifestations of Chronic HCV -- Chronic HCV and HIV Co-infection -- Chronic HCV in Patients with Renal Disease -- Does Treatment Alter the Natural History of Chronic HCV -- Treatment with Interferon and Ribavirin -- Immune Modulators and Other Agents -- Measuring HCV RNA and Assessing Virologic Response -- Response Guided Therapy -- Managing the Side Effects of Therapy -- The Genetics of Virologic Response -- Maintenance Therapy with Peginterferon -- Anti-viral Targets in HCV -- Mutations and the Development of Anti-viral Resistance -- Peginterferon, Ribavirin and Anti-viral Triple Therapy -- Treating Chronic HCV without Interferon and/or Ribavirin -- Maintenance Therapy with Oral Anti-viral Agents -- Natural History of Chronic HCV after Liver Transplantation -- Use of HCV Positive Organs in Patients with and without Chronic HCV -- Treating HCV Prior to Liver Transplantation -- Treating HCV after Liver Transplantation.
Format
e-Book
Location
Online
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Chronic Viral Hepatitis : Diagnosis and Therapeutics

https://libcat.nshealth.ca/en/permalink/provcat29108
edited by Kirti Shetty, George Y. Wu. --Totowa, NJ: Humana Press , c2010.
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Location
Online
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Author
Shetty, Kirti
Other Authors
Wu, George Y
Responsibility
edited by Kirti Shetty, George Y. Wu
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2010
Series Title
Clinical gastroenterology
ISBN
9781597455657
Subjects (MeSH)
Chronic Disease
Hepatitis, Viral, Human - diagnosis
Hepatitis, Viral, Human - therapy
Specialty
Gastroenterology
Virology
Format
e-Book
Location
Online
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The Clinical Diagnosis and Treatment for New Coronavirus Pneumonia

https://libcat.nshealth.ca/en/permalink/provcat45192
Fanjun Cheng, Yu Zhang, editors. --Singapore: Springer ; People's Medical Publishing House , c2020.
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This book is a practical manual for anti-COVID-19. Content of this manual includes: Medical administration under emergent circumstances, protection and control of hospital infection, clinical practice guidance for diagnosis and therapy, the application of radiation for the examination, laboratory diagnosis, inhabitation of inflammatory cytokines crisis, plasma of patient in the recovery stage, and traditional Chinese medical science etcetera. Authors are from Union hospital, Tongji medical coll…
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Cheng, Fanjun
Zhang, Yu
Responsibility
Fanjun Cheng, Yu Zhang, editors
Place of Publication
Singapore
Publisher
Springer ; People's Medical Publishing House
Date of Publication
c2020
Physical Description
1 online resource (xxi, 170 p.) : 21 illus., 2 illus. in color
ISBN
9789811559754
9789811559747 (Print ed.)
9789811559761 (Print ed.)
9789811559778 (Print ed.)
Subjects (MeSH)
Coronavirus Infections - diagnosis
Coronavirus Infections - therapy
Other Subjects
COVID-19
Specialty
Infectious Disease Medicine
Virology
Abstract
This book is a practical manual for anti-COVID-19. Content of this manual includes: Medical administration under emergent circumstances, protection and control of hospital infection, clinical practice guidance for diagnosis and therapy, the application of radiation for the examination, laboratory diagnosis, inhabitation of inflammatory cytokines crisis, plasma of patient in the recovery stage, and traditional Chinese medical science etcetera. Authors are from Union hospital, Tongji medical college in Wuhan city, who has first-hand experiences. This book is a collection and fusion of such experiences in fighting against epidemic infectious disease. It is a timely book for doctors who are fighting against COVID-19.
Contents
1. Emergency System of Designated Hospital for COVID-19 -- 2. Hospital Infection Prevention and Control Against COVID-19 -- 3. COVID-19 Diagnosis -- 4. Clinical Treatment of COVID-19 - 5. Treatment of Critical COVID-19 Patients -- 6. Special Diagnosis and Treatment for Patients with COVID-19 -- 7. Special Clinical Care -- 8. Guidelines and Guidance.
Format
e-Book
Location
Online
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Diagnosis and Management of Autoimmune Hepatitis : A Clinical Guide

https://libcat.nshealth.ca/en/permalink/provcat45356
Mark W. Russo, editor. --Cham: Springer , c2020.
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This text provides a concise yet comprehensive overview of autoimmune hepatitis (AIH). The book reviews diagnosis criteria for AIH, biochemical and histologic findings in typical and atypical cases, and treatment with first, second, and third line therapies. Furthermore, the book discusses management of AIH for specific patient populations, including pediatric patients, pregnant patients, and patients undergoing liver transplantation. Criteria for stopping therapy and risk of relapse, studies d…
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Other Authors
Russo, Mark W.
Responsibility
Mark W. Russo, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (x, 166 p.) : 35 illus., 33 illus. in color
ISBN
9783030336288
9783030336271 (Print ed.)
9783030336295 (Print ed.)
9783030336301 (Print ed.)
Subjects (MeSH)
Hepatitis, Autoimmune
Specialty
Allergy and Immunology
Gastroenterology
Virology
Abstract
This text provides a concise yet comprehensive overview of autoimmune hepatitis (AIH). The book reviews diagnosis criteria for AIH, biochemical and histologic findings in typical and atypical cases, and treatment with first, second, and third line therapies. Furthermore, the book discusses management of AIH for specific patient populations, including pediatric patients, pregnant patients, and patients undergoing liver transplantation. Criteria for stopping therapy and risk of relapse, studies demonstrating the efficacy and safety of alternatives to corticosteroids, and diagnosis and treatment of overlap syndromes are also explored in the text. Written by experts in the field, Diagnosis and Treatment of Autoimmune Hepatitis: A Clinical Guide is a state-of-the-art resource for clinicians and practitioners who treat and manage patients with AIH.
Contents
Epidemiology and Burden of Disease -- The Pathogenesis of Autoimmune Liver Diseases -- Clinical Presentation and Diagnosis -- The Pathology of Autoimmune Hepatitis -- Treating the Adult Patient-First Line Therapy -- Treating the Adult Patient: Alternative Drug Therapies -- The Approach to the Pediatric Patient -- Autoimmune Hepatitis and Pregnancy -- Liver Transplantation for Autoimmune Hepatitis -- Autoimmune Overlap Syndromes -- Drug Induced Liver Injury with Autoimmune Features.
Format
e-Book
Location
Online
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Diagnostic Imaging of Novel Coronavirus Pneumonia

https://libcat.nshealth.ca/en/permalink/provcat45193
Minming Zhang, Bin Lin, editors. --Singapore: Springer ; Henan Science and Technology Press , c2020.
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Online
This book presents radiological findings in patients with 2019 Novel Coronavirus Pneumonia (COVID-19). It starts with a general review of COVID-19 pneumonia discovery, including etiology characteristics, transmission routes and pathogenic mechanisms. In the following chapters, details in clinical classification, imaging manifestations in different groups, and imaging features of family aggregated coronavirus pneumonia are introduced. In addition, key points in differential diagnosis of COVID-19…
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Other Authors
Zhang, Minming
Lin, Bin
Responsibility
Minming Zhang, Bin Lin, editors
Place of Publication
Singapore
Publisher
Springer ; Henan Science and Technology Press
Date of Publication
c2020
Physical Description
1 online resource (x, 242 p.) : 252 illus., 80 illus. in color
ISBN
9789811559921
9789811559914 (Print ed.)
9789811559938 (Print ed.)
9789811559945 (Print ed.)
Subjects (MeSH)
Coronavirus Infections - diagnostic imaging
Other Subjects
COVID-19
Specialty
Diagnostic Imaging
Infectious Disease Medicine
Virology
Abstract
This book presents radiological findings in patients with 2019 Novel Coronavirus Pneumonia (COVID-19). It starts with a general review of COVID-19 pneumonia discovery, including etiology characteristics, transmission routes and pathogenic mechanisms. In the following chapters, details in clinical classification, imaging manifestations in different groups, and imaging features of family aggregated coronavirus pneumonia are introduced. In addition, key points in differential diagnosis of COVID-19 Pneumonia are summarized in the last chapter. The book provides a valuable reference source for radiologists and doctors working in the area of COVID-19 pneumonia.
Contents
1. Overview of the COVID-19 -- 2. Clinical Classification and Diagnosis of COVID-19 -- 3. Imaging Manifestations of COVID-19 -- 4. Typical Cases of COVID-19 Pneumonia in Adult -- 5. Imaging Features of COVID-19 in Elder People -- 6. Imaging Features of Familial Clustering of COVID-19 -- 7. Imaging Features of COVID-19 in Children -- 8. Differentiating COVID-19 CT Manifestations from Other Types of Pneumonia.
Format
e-Book
Location
Online
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Handbook of Hepatitis C

https://libcat.nshealth.ca/en/permalink/provcat40074
Nicolas Goossens, Sophie Clément, Francesco Negro, editors. --Cham: Springer International Publishing : Imprint: Adis , c2016.
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Online
This book is a concise and up-to-date review of the clinical features, pathophysiology, diagnosis, and treatment of patients with hepatitis C. Busy health care professionals who want a quick review of hepatitis C and new developments in treatment for hepatitis C will benefit from this succinct guide. Hepatitis C virus primarily infects liver cells and can lead to chronic damage to the liver. Patients with hepatitis C infection often develop liver sequelae such as fibrosis, cirrhosis, and hepato…
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Other Authors
Goossens, Nicolas
Clément, Sophie
Negro, Francesco
Responsibility
Nicolas Goossens, Sophie Clément, Francesco Negro, editors
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Adis
Date of Publication
c2016
Physical Description
1 online resource (xi, 82 p. : 19 illus. in color)
ISBN
9783319280530
9783319280516 (print ed.)
Subjects (MeSH)
Hepacivirus
Hepatitis C
Viral Hepatitis Vaccines - therapeutic use
Specialty
Gastroenterology
Virology
Abstract
This book is a concise and up-to-date review of the clinical features, pathophysiology, diagnosis, and treatment of patients with hepatitis C. Busy health care professionals who want a quick review of hepatitis C and new developments in treatment for hepatitis C will benefit from this succinct guide. Hepatitis C virus primarily infects liver cells and can lead to chronic damage to the liver. Patients with hepatitis C infection often develop liver sequelae such as fibrosis, cirrhosis, and hepatocellular carcinoma if left untreated. It is estimated that 150 million people worldwide are infected with hepatitis C virus, and if eradication is to be achieved it is imperative to diagnose and treat such individuals.
Contents
Introduction -- The HCV particle and its lifecycle -- Clinical features -- Pathophysiology -- Diagnosis -- Management of HCV infection -- Future challenges.
Format
e-Book
Publication Type
Handbook
Location
Online
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Hepatitis B Virus and Liver Disease

https://libcat.nshealth.ca/en/permalink/provcat42905
edited by Jia-Horng Kao, Ding-Shinn Chen. --Singapore: Springer , c2018.
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This book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chap…
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Other Authors
Kao, Jia-Horng
Chen, Ding-Shinn
Responsibility
edited by Jia-Horng Kao, Ding-Shinn Chen
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xvii, 360 p.) : 40 illus., 29 illus. in color
ISBN
9789811048432
9789811048425 (print ed.)
9789811048449 (print ed.)
Subjects (MeSH)
Hepatitis B virus
Hepatitis B
Specialty
Gastroenterology
Virology
Abstract
This book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments as possible cures for HBV infection. The book is a valuable resource for medical students, physicians, and researchers who are interested in management of patients with chronic HBV infection and investigation HBV infection.
Contents
Life cycle and molecular virology -- Unmet needs in basic research: in vitro and in vivo models -- Immunopathogenesis -- Epidemiology and natural history -- Hepatitis B vaccination -- Viral factors and disease progression -- Host genetic factors and disease progression -- Molecular carcinogenesis of HCC -- Interferon therapy and long-term outcomes -- Nucleotide therapy and long-term outcomes -- Combination therapy -- Treatment of patients with HCV, HDV or HIV co-infection -- Management of children and pregnant women -- Management of patients with immunosuppressive therapy -- Towards an HBV cure: discovery of novel agents -- Others: occult HBV infection.
Format
e-Book
Location
Online
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Hepatitis B Virus in Human Diseases

https://libcat.nshealth.ca/en/permalink/provcat39874
Yun-Fan Liaw, Fabien Zoulim, editors. (1st ed.) --Cham: Springer International Publishing : Imprint: Humana Press , c2016.
Available Online
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Location
Online
This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for students, clinicians, and researchers with an interest in hepatitis B. The book reviews new data about basic and translational science including the viral life cycle, the immunopathogenesis of virus induced chronic hepatitis, the mechanism of virus induced liver cancer, and their potential applications for the clinical management of patients. The clinical aspects of this chronic …
Available Online
View e-Book
Other Authors
Liaw, Yun-Fan
Zoulim, Fabien
Responsibility
Yun-Fan Liaw, Fabien Zoulim, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Humana Press
Date of Publication
c2016
Physical Description
1 online resource (xvi, 468 p. : 58 illus., 44 illus. in color)
Series Title
Molecular and translational medicine
ISBN
9783319223308
9783319223292 (print ed.)
ISSN
2197-7852
Subjects (MeSH)
Hepatitis B virus
Hepatitis B
Specialty
Gastroenterology
Virology
Abstract
This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for students, clinicians, and researchers with an interest in hepatitis B. The book reviews new data about basic and translational science including the viral life cycle, the immunopathogenesis of virus induced chronic hepatitis, the mechanism of virus induced liver cancer, and their potential applications for the clinical management of patients. The clinical aspects of this chronic viral infection are reviewed in detail with important chapters on the global epidemiology, the natural history of the disease, co-infections with its satellite virus HDV or HIV, and management of special patient populations. A major emphasis is made on the management of antiviral therapy and the recent international guidelines for the treatment of hepatitis B. Finally, the book reviews the current state of the art regarding immunoprophylaxis to prevent the spread of the virus and its major clinical consequences. The new advances and perspectives in the development of improved antiviral treatments are also discussed. Hepatitis B Virus in Human Diseases will serve as a very useful resource for students, physicians and researchers dealing with, and interested in, this challenging chronic viral infection. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.
Contents
1. Hepatitis B Virus Virology and Replication -- 2. Experimental Models: Cell Culture and Animal Models -- 3. Hepatitis B Virus Genotypes -- 4. Hepatitis B Virus Immunopathogenesis -- 5. Pathobiology of Hepatitis B Virus-Induced Carcinogenesis -- 6. Hepatitis B Virus: Persistence and Clearance -- 7. Hepatitis Delta Virus: Virology and Replication -- 8. Translational Medicine in Hepatitis B Virus: What Can We Learn from Clinical Samples? -- 9. Global Epidemiology of Hepatitis B Virus Infection -- 10. Clinical Virology: Diagnosis and Virologic Monitoring -- 11. Natural History of Hepatitis B Virus Infection -- 12. Natural History of HBV Infection in the Community -- 13. Occult HBV Infection -- 14. The Basis for Antiviral Therapy: Drug Targets, Cross-Resistance, and Novel Small Molecule Inhibitors -- 15. IFN-Based Therapy and Management of Patients -- 16. Nucleos(t)ide Analogue-Based Therapy and Management of Patients -- 17. Organ Transplantation in HBV-Infected Patients -- 18. Reactivation of Hepatitis B Virus Due to Cancer Chemotherapy and Other Immunosuppressive Drug Therapy -- 19. Immunoprophylaxis of Hepatitis B Virus Infection and Its Sequelae -- 20. Towards HBV Eradication: Future Perspective.
Format
e-Book
Location
Online
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Hepatitis : causes, treatments and resources

https://libcat.nshealth.ca/en/permalink/provcat23093
Moore, Elaine A. --Jefferson, NC: McFarland and Co. , 2006.
Call Number
WI 715 M821h 2006
Location
Dickson Building
Call Number
WI 715 M821h 2006
Author
Moore, Elaine A
Place of Publication
Jefferson, NC
Publisher
McFarland and Co.
Date of Publication
2006
Physical Description
346 p.
ISBN
9780786426232
Subjects (MeSH)
Hepatitis
Specialty
Gastroenterology
Virology
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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Hepatitis C Virus and Liver Transplantation

https://libcat.nshealth.ca/en/permalink/provcat39602
Marina Berenguer, editor. --New York, NY: Springer , c2014.
Available Online
View e-Book
Location
Online
Hepatitis C Virus and Liver Transplantation is designed to provide a comprehensive and state-of-the-art overview of the major issues specific to the field of liver transplantation and hepatitis C virus infection. The sections of the book have been structured to review the overall scope of issues of recurrent hepatitis C in different complex settings, including retransplantation, HIV-coinfected patients or in the setting of suboptimal graft donors. This book provides up-to-date information on th…
Available Online
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Other Authors
Berenguer, Marina
Responsibility
Marina Berenguer, editor
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (x, 123 p. : 13 illus., 8 illus. in color)
ISBN
9781461484387
9781461484370 (print ed.)
Subjects (MeSH)
Donor Selection
Hepatitis C - complications
Hepatitis C - therapy
Liver Cirrhosis - etiology
Liver Transplantation - methods
Postoperative Complications - prevention & control
Secondary Prevention
Specialty
Gastroenterology
Surgical Procedures, Operative
Virology
Abstract
Hepatitis C Virus and Liver Transplantation is designed to provide a comprehensive and state-of-the-art overview of the major issues specific to the field of liver transplantation and hepatitis C virus infection. The sections of the book have been structured to review the overall scope of issues of recurrent hepatitis C in different complex settings, including retransplantation, HIV-coinfected patients or in the setting of suboptimal graft donors. This book provides up-to-date information on the application of new therapies to the field of liver transplantation. It provides the most recent data on their efficacy, the management of side effects, as well as the potential interactions and specific problems associated with their use in the transplant setting. Finally, an appraisal of the risks and benefits of using organs from anti-HCV positive donors is presented. This book provides concise and actual materials for several important topics that are simply not adequately covered by current available literature. Hepatitis C Virus and Liver Transplantation will provide a unique and valuable resource in the field of liver transplantation and will be of great value to Hepatologists, Transplant and Abdominal Surgeons, Oncologists, as well as Fellows and Residents training in these fields.
Contents
1. Treatment of Hepatitis C Before Liver Transplantation -- 2. Donor-Recipient Matching in HCV-Infected Patients -- 3. Natural History of Recurrent Hepatitis C: Impact of Immunosuppression -- 4. Treatment of Hepatitis C After Liver Transplantation -- 5. Hepatitis C and Liver Transplantation in the HIV Co-Infected Patients -- 6. Liver Transplantation for Hepatocellular Carcinoma in HCV-Infected Patients -- 7. Retransplantation for HCV-Related Liver Disease -- 8. Use of Anti-HCV Positive Grafts in Liver Transplantation.
Format
e-Book
Location
Online
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Hepatitis C viruses : genomes and molecular biology

https://libcat.nshealth.ca/en/permalink/provcat23039
Tan, Seng-Lai. --Wymondham, Norfolk, UK: Horizon Bioscience , 2006.
Call Number
QW 170 H529 2006
Location
Dickson Building
Call Number
QW 170 H529 2006
Author
Tan, Seng-Lai
Place of Publication
Wymondham, Norfolk, UK
Publisher
Horizon Bioscience
Date of Publication
2006
Physical Description
469 p.
ISBN
1904933203
Subjects (MeSH)
Hepacivirus - genetics
Genomics
Molecular Biology
Specialty
Genetics, Medical
Molecular Medicine
Virology
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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Hepatitis C Virus II : Infection and Disease

https://libcat.nshealth.ca/en/permalink/provcat40421
Tatsuo Miyamura, Stanley M. Lemon, Christopher M. Walker, Takaji Wakita, editors. --Tokyo: Springer Japan , c2016.
Available Online
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Location
Online
This book helps scientists, clinicians and other interested individuals understand recent clinical advances and challenges for the future. It covers many basic aspects of the pathogenesis of chronic hepatitis C, HCV infections in particular populations, approaches to therapy, and prevention and control of HCV Infection. The book provides a succinct review of the large amount of data generated by multiple groups over the past two decades that has revealed the natural history of HCV infection. Si…
Available Online
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Other Authors
Miyamura, Tatsuo
Lemon, Stanley M
Walker, Christopher M
Wakita, Takaji
Responsibility
Tatsuo Miyamura, Stanley M. Lemon, Christopher M. Walker, Takaji Wakita, editors
Place of Publication
Tokyo
Publisher
Springer Japan
Date of Publication
c2016
Physical Description
1 online resource (ix, 372 p. : 25 illus., 23 illus. in color)
ISBN
9784431561019
9784431560999 (print ed.)
Subjects (MeSH)
Antiviral Agents - therapeutic use
Hepatitis C, Chronic
Hepatitis C Virus
Specialty
Gastroenterology
Virology
Abstract
This book helps scientists, clinicians and other interested individuals understand recent clinical advances and challenges for the future. It covers many basic aspects of the pathogenesis of chronic hepatitis C, HCV infections in particular populations, approaches to therapy, and prevention and control of HCV Infection. The book provides a succinct review of the large amount of data generated by multiple groups over the past two decades that has revealed the natural history of HCV infection. Similarly, it summarizes current understanding of the origins of HCV-associated hepatocellular carcinoma, cirrhosis and hepatic fibrosis. Extra-hepatic manifestation and metabolic disorders related to HCV infection are described. In this volume, these clinically important aspects of HCV infection are comprehensively described. Highlights are description of newly developed direct- acting antivirals. The authors represent a worldwide distribution of leaders in the field reflecting the global nature of HCV infection. Based on recent data concerning the genetic- and geographical diversity of HCV, and increased global disease burden of HCV infection, challenges for global control of HCV infections are described.
Contents
Part I. Chronic Hepatitis C -- Natural History of Chronic Hepatitis C -- The Multifaceted Features of HCV Infection Beyond the Liver -- Hepatic Fibrosis in Hepatitis C -- Hepatocellular Carcinoma and Hepatitis C Virus -- HCV, Alcohol, and the Liver -- Extrahepatic Replication of HCV -- Part II. HCV Infections in Special Populations -- Hepatitis C Virus Infection in Pregnancy and Childhood -- Part III. Approaches to Therapy -- Host Genetics and Responses to Antiviral Therapy in Chronic Hepatitis C -- Viral Variation and Response to Therapy -- HCV NS3/4A Protease Inhibitors and the Road to Effective Direct-Acting Antiviral Therapies -- Mechanism of Action of Direct-Acting Antivirals: New Insights into the HCV Life Cycle -- Modeling HCV Dynamics in Clinical Practice to Personalize Antiviral Therapy -- Part IV. Prevention and Control of HCV Infection -- Prophylactic Vaccines for the Hepatitis C Virus -- Global Control of Hepatitis C Virus Infection.
Format
e-Book
Location
Online
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Hepatitis C Virus Treatment : Highly Effective Therapy with Direct Acting Antivirals and Associated Viral Resistance

https://libcat.nshealth.ca/en/permalink/provcat41957
Kazuaki Chayama, editor. --Singapore: Springer , 2017.
Available Online
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Location
Online
This book introduces readers to Direct Acting Antiviral (DAAs) agents, newly developed drugs to treat chronic hepatitis C virus infection, which have an excellent anti-viral effect on virus replication. These drugs have been developed to enhance the effect of interferon and ribavirin, as the resistant strains against each drug have been described both in vitro and in vivo and the existences of naturally occurring variants have been reported. However, since the combination of different classes o…
Available Online
View e-Book
Other Authors
Chayama, Kazuaki
Responsibility
Kazuaki Chayama, editor
Place of Publication
Singapore
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (vii, 75 pages) : 23 illus., 14 illus. in color
ISBN
9789811024160
9789811024153 (print ed.)
Subjects (MeSH)
Antiviral Agents - therapeutic use
Drug Resistance, Viral
Hepacivirus - drug effects
Hepatitis C - drug therapy
Treatment Outcome
Specialty
Gastroenterology
Virology
Abstract
This book introduces readers to Direct Acting Antiviral (DAAs) agents, newly developed drugs to treat chronic hepatitis C virus infection, which have an excellent anti-viral effect on virus replication. These drugs have been developed to enhance the effect of interferon and ribavirin, as the resistant strains against each drug have been described both in vitro and in vivo and the existences of naturally occurring variants have been reported. However, since the combination of different classes of DAAs is sufficient to completely eradicate the virus without the need for interferon or ribavirin, the current treatment regimen does not include interferon. Ribavirin is used in combination with sofosbuvir, a potent polymerase inhibitor, to enhance its antiviral effects. Hepatitis C Virus Treatment offers readers a comprehensive guide to hepatitis C; describing the resistance profiles against these drugs and shedding light on the difficulties involved in DAA therapy and the direction of future treatments, it will equip doctors to understand the essentials of treating the disease. It also describes in detail new and innovative DAA treatments, the effects of the agents, and the characteristics of resistance, providing cutting-edge information not only for hepatologists, but also for researchers, clinical residents, and medical students.
Contents
1. Treatment of Chronic Hepatitis C with the First-Generation Protease Inhibitor Telaprevir: Its Efficacy and Resistance Mutations -- 2. Features of the Second Wave of the First Generation Protease Inhibitors: Effect and Tolerance -- 3. The Efficacy of Daclatasvir Plus Asunaprevir Combination Therapy with Chronic Hepatitis -- 4. Resistance-Associated Variants in the NS5A Region of HCV and Methods for the Detection -- 5. Detection of Antiviral Drug-Resistant Variants in Chronic Hepatitis C by Deep Sequencing -- 6. Incidence and Characteristics of Naturally Occurring Drug-Resistant Hepatitis C Virus Strains -- 7. Treatment Effects and Resistance- Associated Variants of Sofosbuvir Regimen for Japanese Patients with Chronic Hepatitis C Virus Genotypes 1 and 2 -- 8. Emerging Antivirals in the Future.
Format
e-Book
Location
Online
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