Handbook of cancer treatment-related toxicities
https://libcat.nshealth.ca/en/permalink/provcat46233
Vamsi Velcheti, Salman R. Punekar.
--Philadelphia, PA:
Elsevier
, c2022.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
Early recognition and management of adverse effects of cancer treatments are essential for optimal care of patients with cancer, and drastically different approaches are required for different physiologic reactions. Handbook of Cancer Treatment-Related Symptoms and Toxicities is a focused, one-stop resource that enables clinicians to quickly find up-to-date, reliable information needed at the point of care. The high-yield approach prioritizes the most common toxicities associated with cancer t…
- Available Online
- View e-Book
- Author
- Velcheti, Vamsi
- Responsibility
- Vamsi Velcheti, Salman R. Punekar
- Alternate Title
- Cancer treatment-related toxicities
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- c2022
- Physical Description
- 1 online resource, 466 p.
- ISBN
- 9780323672412
- Subjects (MeSH)
- Neoplasms
- Drug-Related Side Effects and Adverse Reactions
- Specialty
- Medical Oncology
- Pharmacology
- Toxicology
- Abstract
- Early recognition and management of adverse effects of cancer treatments are essential for optimal care of patients with cancer, and drastically different approaches are required for different physiologic reactions. Handbook of Cancer Treatment-Related Symptoms and Toxicities is a focused, one-stop resource that enables clinicians to quickly find up-to-date, reliable information needed at the point of care. The high-yield approach prioritizes the most common toxicities associated with cancer treatment, and concise, templated chapters offer fast access to information needed in day-to-day practice.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Drug Allergy : Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships
https://libcat.nshealth.ca/en/permalink/provcat46495
Brian A. Baldo, Nghia H. Pham.
(Second edition)
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Location
- Online
The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships. New content expands to two areas of drug allergy…
- Available Online
- View e-Book
- Author
- Baldo, Brian A.
- Other Authors
- Pham, Nghia H.
- Responsibility
- Brian A. Baldo, Nghia H. Pham
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (xxii, 732 p.) : 330 illus., 162 illus. in color
- ISBN
- 9783030517403
- 9783030517397 (Print ed.)
- 9783030517410 (Print ed.)
- 9783030517427 (Print ed.)
- Subjects (MeSH)
- Drug Hypersensitivity
- Drug-Related Side Effects and Adverse Reactions
- Structure-Activity Relationship
- Specialty
- Allergy and Immunology
- Pharmacology
- Toxicology
- Abstract
- The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships. New content expands to two areas of drug allergy that have recently experienced explosive growth: biological therapies and new targeted chemotherapies. Other new and expanded chapters address antimicrobials; drugs used in anesthesia and surgery; opioids; non-targeted anti-cancer drugs; vaccines; and newly understood reaction mechanisms. This new edition includes photographs of a wide variety of cutaneous manifestations that will be of use to other clinicians as well as allergists and dermatologists. In addition to its wide clinical emphasis, the book’s mechanistic and structure-activity detail will provide valuable background for researchers and investigators in universities, medical research institutes, drug companies, and regulatory agencies. The second edition of Drug Allergy is an essential reference for practitioners across the medical disciplines from specialist clinicians, surgeons, GPs, residents, and medical students to nurses, pharmacists, dentists, and those taking undergraduate and graduate courses in the biomedical sciences.
- Contents
- 1. Scope of this Book: Adverse Reactions to Drugs and Drug Allergy -- 2. Classification and Descriptions of Allergic Reactions to Drugs -- 3. Mechanisms of Hypersensitivity -- 4. Diagnosis of Allergic Reactions to Drugs -- 5. ß-Lactam Antibiotics -- 6. Other Antimicrobial Drugs -- 7. Drugs and Other Agents Used in Anesthesia and Surgery -- 8. Opioid Analgesic Drugs -- 9. Non-steroidal Anti-inflammatory Drugs -- 10. Contrast Media -- 11. Corticosteroids -- 12. Proton Pump Inhibitors -- 13. Biologics: Monoclonal Antibodies for Non-cancer Therapy, Cytokines, Fusion Proteins, Enzymes, and Hormones -- 14. Targeted Drugs for Cancer Therapy: Small Molecules and Monoclonal Antibodies -- 15. Non-targeted Drugs for Cancer Therapy -- 16. Vaccines.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Drug-induced Neurological Disorders
https://libcat.nshealth.ca/en/permalink/provcat46971
Kewal K. Jain.
(Fourth edition)
Springer
, 2021.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Responsibility
- Kewal K. Jain
- Edition
- Fourth edition
- Publisher
- Springer
- Date of Publication
- 2021
- Physical Description
- 1 online resource (xxvii, 604 pages) : illustrations
- ISBN
- 9783030735036
- Specialty
- Neurology
- Pharmacology
- Toxicology
- Format
- e-Book
- Location
- Online
Drug-induced ocular side effects
https://libcat.nshealth.ca/en/permalink/provcat50625
Fraunfelder, Frederick T.
(8th ed.)
--Philadelphia, PA:
Elsevier
, 2021.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Fraunfelder, Frederick T.
- Edition
- 8th ed.
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- 2021
- ISBN
- 9780323653756
- Subjects (MeSH)
- Toxicology - methods
- Eye Diseases - chemically induced
- Eye - drug effects
- Drug-Related Side Effects and Adverse Reactions
- Notes
- Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
- Format
- e-Book
- Location
- Online
Drug-induced ocular side effects
https://libcat.nshealth.ca/en/permalink/provcat42359
Frederick "Fritz" T. Fraunfelder, Frederick "Rick" W. Fraunfelder.
(8th ed.)
--London, UK:
Elsevier
, c2021.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
- Available Online
- View e-Book
- Author
- Fraunfelder, Frederick
- Responsibility
- Frederick "Fritz" T. Fraunfelder, Frederick "Rick" W. Fraunfelder
- Edition
- 8th ed.
- Alternate Title
- Drug induced ocular side effects
- Ocular side effects
- Place of Publication
- London, UK
- Publisher
- Elsevier
- Date of Publication
- c2021
- Physical Description
- 1 online resource
- ISBN
- 9780323653756
- Subjects (MeSH)
- Drug-Related Side Effects and Adverse Reactions
- Eye Diseases - chemically induced
- Eye - drug effects
- Toxicology - methods
- Specialty
- Ophthalmology
- Pharmacology
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Hunter's tropical medicine and emerging infectious diseases
https://libcat.nshealth.ca/en/permalink/provcat32071
Edward T. Ryan ... [et al.].
(10th ed.)
--Edingburgh, UK:
Elsevier
, c2020.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
New emerging diseases, new diagnostic modalities for resource-poor settings, new vaccine schedules … all significant, recent developments in the fast-changing field of tropical medicine. Hunter’s Tropical Medicine and Emerging Infectious Diseases, 10th Edition, keeps you up to date with everything from infectious diseases and environmental issues through poisoning and toxicology, animal injuries, and nutritional and micronutrient deficiencies that result from traveling to tropical or subtropica…
- Available Online
- View e-Book
- Other Authors
- Ryan, Edward T.
- Responsibility
- Edward T. Ryan ... [et al.]
- Edition
- 10th ed.
- Alternate Title
- Tropical medicine & emerging infectious diseases
- Place of Publication
- Edingburgh, UK
- Publisher
- Elsevier
- Date of Publication
- c2020
- Physical Description
- 1 online resource, p.
- ISBN
- 9780323555128
- Subjects (MeSH)
- Tropical Medicine
- Subjects (LCSH)
- Tropical Medicine
- Emerging infectious diseases
- Specialty
- Infectious Disease Medicine
- Tropical Medicine
- Abstract
- New emerging diseases, new diagnostic modalities for resource-poor settings, new vaccine schedules … all significant, recent developments in the fast-changing field of tropical medicine. Hunter’s Tropical Medicine and Emerging Infectious Diseases, 10th Edition, keeps you up to date with everything from infectious diseases and environmental issues through poisoning and toxicology, animal injuries, and nutritional and micronutrient deficiencies that result from traveling to tropical or subtropical regions. This comprehensive resource provides authoritative clinical guidance, useful statistics, and chapters covering organs, skills, and services, as well as traditional pathogen-based content. You’ll get a full understanding of how to recognize and treat these unique health issues, no matter how widespread or difficult to control.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
The Washington manual of medical therapeutics
https://libcat.nshealth.ca/en/permalink/provcat32678
editors, Zachary Crees ... [et al.].
(36th ed.)
--Philadelpha, PA:
Wolters Kluwer
, c2020.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Corporate Author
- Washington University Department of Medicine
- Other Authors
- Crees, Zachary
- Fritz, Cassandra
- Heudebert, Alonso
- Noé, Jonas
- Rengarajan, Arvind
- Wang, Xiaowen
- Responsibility
- editors, Zachary Crees ... [et al.]
- Edition
- 36th ed.
- Place of Publication
- Philadelpha, PA
- Publisher
- Wolters Kluwer
- Date of Publication
- c2020
- Physical Description
- [954 p.]
- ISBN
- 9781975113513 (pbk.)
- 9781975113483 (e-ISBN)
- Subjects (MeSH)
- Therapeutics
- Specialty
- Clinical Medicine
- Contents
- 1. Patient Care in Internal Medicine -- 2. Nutrition Support -- 3. Preventive Cardiology -- 4. Ischemic Heart Disease -- 5. Heart Failure and Cardiomyopathy -- 6. Pericardial and Valvular Heart Disease -- 7. Cardiac Arrhythmias -- 8. Critical Care -- 9. Obstructive Lung Disease -- 10. Pulmonary Diseases -- 11. Allergy and Immunology -- 12. Fluid and Electrolyte Management -- 13. Renal Diseases -- 14. Treatment of Infectious Diseases -- 15. Antimicrobials -- 16. Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome -- 17. Solid Organ Transplant Medicine -- 18. Gastrointestinal Diseases -- 19. Liver Diseases -- 20. Disorders of Hemostasis and Thrombosis -- 21. Hematologic Disorders and Transfusion Therapy -- 22. Medical Management of Malignant Disease -- 23. Diabetes Mellitus and Related Disorders -- 24. Endocrine Diseases -- 25. Arthritis and Rheumatologic Diseases -- 26. Neurologic Disorders -- 27. Medical Emergencies -- 28. Toxicology -- Appendix A. Immunizations and Postexposure Therapies -- Appendix B. Infection Control and Isolation Recommendations -- Appendix C. Advanced Cardiac Life Support Algorithms -- Index.
- Format
- e-Book
- Publication Type
- Handbook
- Location
- Online
Skin Decontamination : A Comprehensive Clinical Research Guide
https://libcat.nshealth.ca/en/permalink/provcat44826
Hanjiang Zhu, Howard I. Maibach, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. However, some chemicals act directly on the skin including vesicants sulfur mustard and corrosive compounds such as strong acids or bases, and do not have to gain access to systemic circulation to cause extensive skin damage. Early and rapid skin decontamination is extremely important following exposure to ch…
- Available Online
- View e-Book
- Other Authors
- Zhu, Hanjiang
- Maibach, Howard I.
- Responsibility
- Hanjiang Zhu, Howard I. Maibach, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xi, 280 p.) : 56 illus., 45 illus. in color
- ISBN
- 9783030240097
- 9783030240080 (Print ed.)
- 9783030240103 (Print ed.)
- 9783030240110 (Print ed.)
- Subjects (MeSH)
- Decontamination
- Environmental Exposure - prevention & control
- Skin
- Specialty
- Dermatology
- Environmental Health
- Toxicology
- Abstract
- The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. However, some chemicals act directly on the skin including vesicants sulfur mustard and corrosive compounds such as strong acids or bases, and do not have to gain access to systemic circulation to cause extensive skin damage. Early and rapid skin decontamination is extremely important following exposure to chemical warfare agents and toxic industrial chemicals because it decreases serious skin damage to the patient and, potentially, their doctor. This multi-authored international text pulls together a century of decontamination research and helps the reader expedite solutions that will decrease morbidity and mortality. Complete with dozens of high quality photographs and illustrations, Skin Decontamination aids industrial hygiene, dermatology, occupational physicians and those involved in the public health arena.
- Contents
- 1. Isolated Human and Animal Stratum Corneum As a Partial Model for the 15 Steps of Percutaneous Absorption: Emphasizing Decontamination, Part I -- 2. Isolated Human And Animal Stratum Corneum As A Partial Model For The 15 Steps Of Percutaneous Absorption: Emphasizing Decontamination, Part II -- 3. Recent Knowledge: Human/Animal Skin Decontamination -- 4. The Decontamination of Chemically Contaminated Remains -- 5. Effectiveness of Chemical, Biological, Radiological, and Nuclear (CBRN) Skin Decontaminants: Towards Tests Standardization -- 6. Effects of Soap-Water Wash on Human Epidermal Penetration -- 7. Fuller's Earth: Old and Faithful Skin Decontaminant Against Toxic Agents -- 8. Comparison of Four Different Fuller’s Earth Formulations in Skin Decontamination -- 9. The Mass Decontamination Paradigm: Response Relating to Gas Phase Exposures and Skin Decontamination -- 10. Binding Affinity and Decontamination of Dermal Decontamination Gel (DDGel) to Model Chemical Warfare Agent (CWA) Simulants -- 11. Dermostyx (IB1): High-efficacy and Safe Topical Skin Protectant Against Percutaneous Toxic Agents -- 12. Understanding the Impact of Responder Management Strategies on Public Experiences and Behaviour During Mass Decontamination -- Appendix: Skin, Hair, and Nail: Abbreviated Decontamination Bibliography.
- Format
- e-Book
- Location
- Online
Health Impacts of Developmental Exposure to Environmental Chemicals
https://libcat.nshealth.ca/en/permalink/provcat44872
Reiko Kishi, Philippe Grandjean, editors.
--Singapore:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to the impacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment…
- Available Online
- View e-Book
- Other Authors
- Kishi, Reiko
- Grandjean, Philippe
- Responsibility
- Reiko Kishi, Philippe Grandjean, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xi, 557 p.) : 50 illus., 23 illus. in color
- ISBN
- 9789811505201
- 9789811505195 (Print ed.)
- 9789811505218 (Print ed.)
- 9789811505225 (Print ed.)
- ISSN
- 2364-8333
- Subjects (MeSH)
- Environmental Exposure - adverse effects
- Environmental Health
- Environmental Pollutants - toxicity
- Prenatal Exposure Delayed Effects
- Specialty
- Environmental Health
- Toxicology
- Abstract
- This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to the impacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment, immune functions, etc. In turn, the third part addresses the characteristics of specific chemicals and their effects on human health and development, while the fourth part provides a basis for future studies by highlighting the latest innovations in toxicology, remaining challenges, and promising strategies in children’s environmental health research, as well as ideas on how to bridge the gap between research evidence and practical policymaking. The fifth and last part outlines further research directions and related policymaking aspects. Health Impacts of Developmental Exposure to Environmental Chemicals will appeal to young and veteran researchers, students, and physicians (especially gynecologists and pediatricians) who are seeking comprehensive information on how children’s health can be affected by harmful chemicals and other environmental toxicants.
- Contents
- Part I. Introduction -- 1. Impacts of Developmental Exposure to Environmental Chemicals on Human Health with Global Perspectives -- Part II. Adverse Health Effects on Human Developing Organs Caused by Environmental Chemicals: the Role That Chemicals Might Play -- 2. Environmental Exposures and Adverse Pregnancy-Related Outcomes -- 3. Effects of Environmental Chemical Exposure on Birth Defects (Except Cryptorchidism and Hypospadias) -- 4. Cryptorchidism and Hypospadias -- 5. Endocrine-Distributing Chemicals and Reproductive Function -- 6. Thyroid Hormone System and Development -- 7. Neurodevelopment and Neurobehavioral Disorders in Relation to Developmental Exposures -- 8. Immunotoxicity: Impacts and Research Approaches -- 9. Long-Term Implications of Developmental Programming and Obesity -- Part III. Impact of Environmental Chemical Hazards on Human Development -- 10. Impact of Air Pollution Hazards on Human Development -- 11. Mercury, Lead, Manganese, and Hazardous Metals -- 12. Environmental Pollution and Recent Data on Asian Children’s Health in Relation to Pre- and Early Post-natal Exposure to Persistent Organic Pollutants, Including PCBs, PCDD/PCDFs, and Organochlorine Pesticides -- 13. Effects of Developmental Exposure to Perfluoroalkyl Substances on Health Outcomes in Pregnant Women and Offspring -- 14. Brominated Flame Retardants (BFRs) -- 15. Phthalates -- 16. Bisphenols and Alkylphenols -- Part IV. Important Aspects of Research for Prevention and Strategy -- 17. Adverse Outcome Pathways for Developmental Toxicity -- 18. Exposomics: The Exposome in Early Life -- 19. Gene–Environment Interactions to Detect Adverse Health Effects on the Next Generation -- 20. Epigenetics: Strategies for Prevention Research -- 21. From Research to Intervention -- Part V. Closing -- 22. Further Direction of Research and Policy Making of Environment and Children’s Health.
- Format
- e-Book
- Location
- Online
ICU Protocols : A Step-wise Approach, Vol I
https://libcat.nshealth.ca/en/permalink/provcat44900
Rajesh Chawla, Subhash Todi, editors.
(Second edition)
--Singapore:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
The second edition of this highly successful book includes up-to-date notes on the step-wise management of clinical emergencies encountered in everyday intensive care units (ICU). Each thoroughly revised chapter provides concise information for point-of-care treatment, making it a practical guide clinicians can refer to on a daily basis at work or while traveling, or just to expand their knowledge. Volume 1 of ICU Protocols covers topics in pulmonology, cardiology, neurology, gastroenterology, …
- Available Online
- View e-Book
- Other Authors
- Chawla, Rajesh
- Todi, Subhash
- Other Authors
- Indian Society of Critical Care Medicine
- Responsibility
- Rajesh Chawla, Subhash Todi, editors
- Edition
- Second edition
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xix, 632 p.) : 102 illus., 32 illus. in color
- ISBN
- 9789811508981
- 9789811508974 (Print ed.)
- 9789811508998 (Print ed.)
- 9789811509001 (Print ed.)
- 9789811536922 (Print ed.)
- Subjects (MeSH)
- Clinical Protocols
- Critical Care
- Intensive Care Units
- Patient Care Planning
- Specialty
- Critical Care
- Intensive Care Units
- Abstract
- The second edition of this highly successful book includes up-to-date notes on the step-wise management of clinical emergencies encountered in everyday intensive care units (ICU). Each thoroughly revised chapter provides concise information for point-of-care treatment, making it a practical guide clinicians can refer to on a daily basis at work or while traveling, or just to expand their knowledge. Volume 1 of ICU Protocols covers topics in pulmonology, cardiology, neurology, gastroenterology, nephrology and infectious diseases. The endocrine and metobolic systems, oncology, trauma, toxicology, envenomation and thermodysregulation, obstetrics, and perioperative care are covered in the second volume of ICU Protocols. This two-volume book is a must-read for intensivists, critical care specialists, junior trainees and residents working in ICUs. It is also relevant as course material for workshops on critical care, and essential for all hospital-based libraries. “This book provides junior trainees with an introduction to the management of problems common to the critical care unit.” David J Dries, Doody’s Book Reviews, March, 2013, for the first edition of ICU Protocols.
- Contents
- Part I. Respiratory System -- 1. Airway Management -- 2. Acute Respiratory Failure -- 3. Noninvasive Positive-Pressure Ventilation -- 4. High Flow Nasal Canula (HFNC) -- 5. Basic Mechanical Ventilation -- 6. Mechanical Ventilation in Acute Respiratory Distress Syndrome -- 7. Management of Refractory Hypoxemia in Acute Respiratory Distress Syndrome -- 8. Mechanical Ventilation in Obstructive Airway Diseases -- 9. Weaning -- 10. Massive Hemoptysis -- 11. Pulmonary Thromboembolism -- 12. Severe Community-Acquired Pneumonia -- 13. Ventilator-Associated Pneumonia -- 14. Pleural Diseases -- 15. Sleep-Disordered Breathing -- 16. Oxygen Therapy -- 17. Pulse Oximetry and Capnography -- Part II. Cardiovascular System -- 18. Hemodynamic Monitoring -- 19. Echocardiography -- 20. Fluid Therapy, Vasopressors, and Inotropes -- 21. Cardiorespiratory Arrest -- 22. Cardiogenic Shock -- 23. Acute Heart Failure -- 24. Cardiac Arrhythmias -- 25. Acute Coronary Syndromes -- 26. Hypertensive Urgencies and Emergencies -- Part III. Nervous System -- 27. Acute Ischemic Stroke -- 28. Spontaneous Intracerebral Hemorrhage -- 29. Subarachnoid Hemorrhage -- 30. Status Epilepticus -- 31. Acute Flaccid Paralysis -- 32. Coma -- 33. Intracranial Pressure Monitoring and Management - 34. Acute Febrile Encephalopathy -- 35. Sedation and Analgesia -- 36. Brain Death -- Part IV. Gastrointestinal System -- 37. Upper Gastrointestinal Bleeding -- 38. Lower Gastrointestinal Bleeding -- 39. Acute Diarrhea -- 40. Acute Abdominal Distension -- 41. Intra-abdominal Hypertension -- 42. Acute Pancreatitis -- 43. Acute Liver Failure -- 44. Acute Decompensation in Chronic Liver Failure -- 45. Nutrition Support -- Part V. Renal System -- 46. Acute Kidney Injury -- 47. Renal Replacement Therapy -- 48. Managing a Patient on Dialysis -- 49. Drug Dosing in Renal Failure in ICU -- Part VI. Infection Diseases -- 50. General Measures of Infection Control -- 51. Antibiotic Stewardship -- 52. Septic Shock -- 53. Severe Tropical Infections -- 54. New-Onset Fever -- 55. Fungal Infections -- 56. Infections in the Immunocompromised Host -- 57. Central Line Related Blood Stream Infections (CRBSI) -- 58. Antibiotic Pearls: A Case Based Discussion.
- Format
- e-Book
- Location
- Online
Prevention and Management of Acute and Late Toxicities in Radiation Oncology : Management of Toxicities in Radiation Oncology
https://libcat.nshealth.ca/en/permalink/provcat45229
Gokhan Ozyigit, Ugur Selek, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book is an evidence-based guide to the prevention and current management of acute and late toxicities of radiation therapy for a wide range of malignancies. Each chapter focuses on a particular anatomic site and provides information on normal sectional anatomy, contouring of target volumes and organs at risk, dose constraints, the pathophysiology of radiation toxicity, and treatment approaches for each potential toxicity. The information provided will assist in the planning and delivery of…
- Available Online
- View e-Book
- Other Authors
- Ozyigit, Gokhan
- Selek, Ugur
- Responsibility
- Gokhan Ozyigit, Ugur Selek, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xi, 322 p.) : 58 illus., 57 illus. in color
- ISBN
- 9783030377984
- 9783030377977 (Print ed.)
- 9783030377991 (Print ed.)
- 9783030378004 (Print ed.)
- Subjects (MeSH)
- Health Physics
- Neoplasms - radiotherapy
- Radiotherapy - adverse effects
- Radiotherapy Dosage
- Specialty
- Radiotherapy
- Toxicology
- Abstract
- This book is an evidence-based guide to the prevention and current management of acute and late toxicities of radiation therapy for a wide range of malignancies. Each chapter focuses on a particular anatomic site and provides information on normal sectional anatomy, contouring of target volumes and organs at risk, dose constraints, the pathophysiology of radiation toxicity, and treatment approaches for each potential toxicity. The information provided will assist in the planning and delivery of intensity-modulated radiation therapy, including volumetric modulated arc therapy, stereotactic radiosurgery, and stereotactic body radiotherapy. It will also enable the selection of appropriate, evidence-based management options in individual patients who experience radiation toxicities, taking into account the organ-specific pathophysiology of radiation injury. Written by acknowledged experts and featuring numerous high-quality illustrations, the book will be an ideal reference aid for practicing clinical and radiation oncologists, radiotherapists, fellows, residents, and nurses.
- Contents
- 1. Toxicity Management for Central Nervous System Tumors in Radiation Oncology -- 2. Toxicity Management for Head and Neck Tumors in Radiation Oncology-I -- 3. Toxicity Management for Head and Neck Tumors in Radiation Oncology-II -- 4. Toxicity Management for Thorax Tumors in Radiation Oncology -- 5. Toxicity Management for Upper Abdomen Tumors in Radiation Oncology -- 6. Toxicity Management for Pelvic Tumors in Radiation Oncology -- 7. Toxicity Management for Other Sites in Radiation Oncology.
- Format
- e-Book
- Location
- Online
Cannabis in Medicine : An Evidence-Based Approach
https://libcat.nshealth.ca/en/permalink/provcat45327
Kenneth Finn, editor.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
Legalization of marijuana is becoming increasingly prominent in the United States and around the world. While there is some discussion of the relationship between marijuana and overall health, a comprehensive resource that outlines the medical literature for several organ systems, as well as non-medical societal effects, has yet to be seen. While all physicians strive to practice evidence-based medicine, many clinicians aren't aware of the facts surrounding cannabis and are guided by public opi…
- Available Online
- View e-Book
- Other Authors
- Finn, Kenneth
- Responsibility
- Kenneth Finn, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xxxi, 554 p.) : 39 illus., 32 illus. in color
- ISBN
- 9783030459680
- 9783030459673 (Print ed.)
- 9783030459697 (Print ed.)
- Subjects (MeSH)
- Cannabinoids - pharmacology
- Cannabinoids - therapeutic use
- Medical Marijuana - therapeutic use
- Specialty
- Pharmacology
- Abstract
- Legalization of marijuana is becoming increasingly prominent in the United States and around the world. While there is some discussion of the relationship between marijuana and overall health, a comprehensive resource that outlines the medical literature for several organ systems, as well as non-medical societal effects, has yet to be seen. While all physicians strive to practice evidence-based medicine, many clinicians aren't aware of the facts surrounding cannabis and are guided by public opinion. This first of its kind book is a comprehensive compilation of multiple facets of cannabis recommendation, use and effects from a variety of different perspectives. Comprised of chapters dedicated to separate fields of medicine, this evidence-based guide outlines the current data, or lack thereof, as well as the need for further study. The book begins with a general overview of the neurobiology and pharmacology of THC and hemp. It then delves into various medical concerns that plague specific disciplines of medicine such as psychiatry, cardiology, gastrointestinal and neurology, among others. The end of the book focuses on non-medical concerns such as public health and safety, driving impairment and legal implications. Comprised of case studies and meta-analyses, Cannabis in Medicine: An Evidence-Based Approach provides clinicians with with a concise, evidence-based guide to various health concerns related to the use of marijuana. By addressing non-medical concerns, this book is also a useful resource for professionals working in the public health and legal fields.
- Contents
- Forward: Losing Ground: The Rise of Cannabis Culture -- Part I. Basic Science -- 1. The Properties and Use of Cannabis Sativa Herb and Extracts -- 2. Cannabinoid and Marijuana Neurobiology -- 3. The Pharmacodynamics, Pharmacokinetics, and Potential Drug Interactions of Cannabinoids -- Part II. Clinical Evidence -- 4. Cannabis and Neuropsychiatric Effects -- 5. Cannabis and the Impact on the Pediatric and Adolescent Population -- 6. Acute Emergency Department Presentations Related to Cannabis -- 7. Evidence of Cannabinoids in Pain -- 8. Cannabis in Pulmonary Medicine -- 9. Clinical Cardiovascular Effects of Cannabis Use -- 10. Cannabinoids in Neurologic Conditions -- 11. Ocular Conditions and the Endocannabinoid System -- 12. Cannabis in Oncology and Symptom Management -- 13. Cannabis in Palliative Medicine -- 14. Cannabis in Older Persons -- 15. Cannabinoids in Dermatology -- 16. Fetal and Neonatal Marijuana Exposure -- 17. Cannabinoids in Gastrointestinal Disorders -- 18. Looking at Marijuana Through the Lens of Public Health -- 19. Cannabis-Impaired Driving: Evidence and the Role of Toxicology Testing -- 20. The Legal Aspects of Marijuana as Medicine -- Epilogue: Epilogue: The Medical Cannabis Landscape.
- Format
- e-Book
- Location
- Online
Prepare for the Pediatric Emergency Medicine Board Examination
https://libcat.nshealth.ca/en/permalink/provcat45544
Muhammad Waseem, Isabel A. Barata, Jennifer H. Chao, David Foster, Noah Kondamudi, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book outlines the essential knowledge required for the management of critically ill and severely injured children. It is designed to facilitate successful completion of the Pediatric Emergency Medicine Board Examination of the American Board of Pediatrics (ABP). Each chapter follows a Question & Answer format, covering major areas in pediatrics such as cardiology, dermatology, nephrology, surgery and trauma. The book concludes with a comprehensive practice test, allowing it to function as …
- Available Online
- View e-Book
- Responsibility
- Muhammad Waseem, Isabel A. Barata, Jennifer H. Chao, David Foster, Noah Kondamudi, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xvi, 755 p.) : 201 illus., 152 illus. in color
- ISBN
- 9783030283728
- 9783030283704 (Print ed.)
- 9783030283711 (Print ed.)
- Subjects (MeSH)
- Critical Illness
- Emergency Medicine
- Pediatrics
- Specialty
- Emergency Medicine
- Pediatrics
- Abstract
- This book outlines the essential knowledge required for the management of critically ill and severely injured children. It is designed to facilitate successful completion of the Pediatric Emergency Medicine Board Examination of the American Board of Pediatrics (ABP). Each chapter follows a Question & Answer format, covering major areas in pediatrics such as cardiology, dermatology, nephrology, surgery and trauma. The book concludes with a comprehensive practice test, allowing it to function as a well-rounded reference and study guide. Prepare for the Pediatric Emergency Medicine Board Examination is an essential resource for any clinician or trainee seeking a concise review of how to manage critically ill and severely injured children.
- Contents
- 1. Resuscitation -- 2. Critical Care and Transport -- 3. Emergency Medical Services -- 4. Environmental Emergencies -- 5. Asthma and Other Emergencies Treated Medically -- 6. Cardiology -- 7. Dermatology -- 8. Neonatal -- 9. Nephrology -- 10. Pediatric Neurology -- 11. Pediatric Gynecology -- 12. Infectious Diseases -- 13. Endocrine and Metabolic Diseases -- 14. Hematology and Oncology -- 15. Toxicology -- 16. Psychosocial Emergencies -- 17. Child Abuse -- 18. ENT -- 19. Pediatric Ophthalmology -- 20. Surgery -- 21. Trauma -- 22. Emergency Obstetric Ultrasound -- 23. Emergency Cardiac Ultrasound -- 24. Emergency Ultrasound in Trauma -- 25. Emergency Point of Care Ultrasound -- 26. Orthopedics -- 27. Procedures -- 28. Dental -- 29. Dental Procedures -- 30. Pediatric Burns -- 31. Snake Envenomation -- 32. Administration -- 33. Epidemiology -- 34. Biostatistics -- 35. Practice Chapter.
- Format
- e-Book
- Publication Type
- Examination Questions
- Location
- Online
Emergency Department Critical Care
https://libcat.nshealth.ca/en/permalink/provcat45604
Joseph R. Shiber, editor ; Scott D. Weingart, consulting editor.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This comprehensive book provides practical guidance on the care of the critical patient in the emergency department. It focuses on the ED physician or provider working in a community hospital where, absent the consulting specialists found in a large academic center, the provider must evaluate and stabilize critically ill and injured patients alone. Structured in an easily accessible format, chapters present fundamental information in tables, bullet points, and flow diagrams. Emergency medicine …
- Available Online
- View e-Book
- Other Authors
- Shiber, Joseph R.
- Weingart, Scott D.
- Responsibility
- Joseph R. Shiber, editor ; Scott D. Weingart, consulting editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xv, 714 p.) : 77 illus.
- ISBN
- 9783030287948
- 9783030287924 (Print ed.)
- 9783030287931 (Print ed.)
- Specialty
- Critical Care
- Emergency Medicine
- Abstract
- This comprehensive book provides practical guidance on the care of the critical patient in the emergency department. It focuses on the ED physician or provider working in a community hospital where, absent the consulting specialists found in a large academic center, the provider must evaluate and stabilize critically ill and injured patients alone. Structured in an easily accessible format, chapters present fundamental information in tables, bullet points, and flow diagrams. Emergency medicine scenarios covered across 38 chapters include acute respiratory failure, spinal cord Injuries, seizures and status epilepticus, care of the newborn, and end-of-life care. Written by experts in the field, Emergency Department Critical Care is an essential resource for practicing emergency physicians and trainees, internists and family physicians, advance practice nurses, and physician’s assistants who provide care in emergency departments and urgent care centers.
- Contents
- 1. Shock Overview -- 2. Airwave Management -- 3. Acute Respiratory Failure -- 4. Non-Invasive and Mechanical Ventilation -- 5. Asthma & COPD -- 6. Acute Respiratory Distress Syndrome -- 7. Pulmonary Embolism and Massive DVT for Emergency Critical Care, Edition -- 8. Acute Coronary Syndrome and Myocardial Infarction -- 9. Cardiac Dysrhythmias -- 10. Left Ventricular Assist Devices and Pacemakers -- 11. Cardiac Arrest and Post-Arrest Syndrome -- 12. Heart Failure -- 13. Hypertensive Emergencies -- 14. Management of Emergency Department Patients with Gastrointestinal Hemorrhage -- 15. Acute Liver Failure and Acute Decompensation of Chronic Liver Failure -- 16. Vascular Emergencies – Aortic Aneurysm, Ischemic Bowel, Ischemic Limb -- 17. Renal Emergencies -- 18. Acid-Base and Electrolyte Disorders -- 19. Sepsis and Septic Shock -- 20. Severe Skin and Soft Tissue Infections -- 21. Stroke: Ischemic & Hemorrhagic -- 22. Seizures and Status Epilepticus -- 23. Spinal Cord Injuries -- 24. Traumatic Brain Injury and Spinal Cord Injury -- 25. Evaluation and management of the poly-trauma patient -- 26. Endocrine Emergencies in the ICU -- 27. Environmental Emergencies -- 28. Toxicology and OD -- 29. Oncologic Emergencies -- 30. Obstetric Emergency Critical Care -- 31. Care of the Newborn -- 32. Pediatrics 1: Intro, Airway, Respiratory, Cardiac, Neuro -- 33. Pediatrics 2: Trauma, Abuse, Drowning, Burns -- 34. Fluids and Vasoactive Agents -- 35. Blood Products -- 36. Inter-hospital Transfer of the Critically Ill -- 37. Ultrasound for Shock Evaluation, Resuscitation, and Critical Care Procedures -- 38. End of Life Care in the Emergency Department.
- Format
- e-Book
- Location
- Online
Uremic Toxins and Organ Failure
https://libcat.nshealth.ca/en/permalink/provcat46096
Hideyuki Saito, Takaaki Abe, editors.
--Singapore:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book describes the latest research on the gut-kidney axis of ureic solutes; the toxico-pathological mechanisms of uremic toxin-induced organ failure, including kidney and cardiovascular tissue; and the preventive therapeutic strategies for uremia and related organ failure associated with kidney injuries and diseases. Retained uremic toxins cause a variety of symptoms, such as hypertension, fatigue, renal anemia, osteoporosis and neurologic impairment, which are apparent in chronic kidney d…
- Available Online
- View e-Book
- Other Authors
- Saito, Hideyuki
- Abe, Takaaki
- Responsibility
- Hideyuki Saito, Takaaki Abe, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (viii, 180 p.) : 39 illus., 22 illus. in color
- ISBN
- 9789811577932
- 9789811577925 (Print ed.)
- 9789811577949 (Print ed.)
- 9789811577956 (Print ed.)
- Subjects (MeSH)
- Kidney Failure, Chronic - complications
- Multiple Organ Failure - physiopathology
- Toxins, Biological - metabolism
- Uremia - metabolism
- Specialty
- Biochemistry
- Toxicology
- Abstract
- This book describes the latest research on the gut-kidney axis of ureic solutes; the toxico-pathological mechanisms of uremic toxin-induced organ failure, including kidney and cardiovascular tissue; and the preventive therapeutic strategies for uremia and related organ failure associated with kidney injuries and diseases. Retained uremic toxins cause a variety of symptoms, such as hypertension, fatigue, renal anemia, osteoporosis and neurologic impairment, which are apparent in chronic kidney disease (CKD) patients. The human gastrointestinal tract contains trillions of microorganisms, referred to as gut microbiota, which support the host metabolism by producing nutrients, such as vitamins and short-chain fatty acids. However, they also produce various harmful uremic toxins that show renal and cardiovascular toxicity, and correlate with an increased mortality in CKD patients. The composition and balance of gut microbiota are associated with the accumulation of uremic toxins and the pathophysiology of CKD, and as such are being considered for a novel therapeutic strategy.
- Contents
- 1. Overview of Uremic Toxins -- 2. Review: Uremic toxins and gut microbiome -- 3. Gut microbiota and systemic uremic solute accumulation -- 4. Uremic toxin-related systemic disorders -- 5. Uremic toxins and cardiovascular disease -- 6. Indoxyl sulfate and arteriosclerosis -- 7. Uremic toxicity and bone in CKD -- 8. D-serine as a novel uremic toxin -- 9. Uremic solutes and sarcopenia -- 10. Toxico-pathological role of hepatic sulfotransferase (SULT) 1A1 in acute kidney injuries -- 11. Accumulation of uremic toxins in systemic organs and the effect of AST-120.
- Format
- e-Book
- Location
- Online
Alternatives to Animal Testing : Proceedings of Asian Congress 2016
https://libcat.nshealth.ca/en/permalink/provcat43939
Hajime Kojima, Troy Seidle, Horst Spielmann, editors.
--Singapore:
SpringerOpen
, c2019.
- Available Online
- View e-Book
- Access
- Open access
- Location
- Online
The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0. ; This book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collective…
- Available Online
- View e-Book
- Other Authors
- Kojima, Hajime
- Seidle, Troy
- Spielmann, Horst
- Responsibility
- Hajime Kojima, Troy Seidle, Horst Spielmann, editors
- Place of Publication
- Singapore
- Publisher
- SpringerOpen
- Date of Publication
- c2019
- Physical Description
- 1 online resource (vi, 130 p. 46 illus., 39 illus. in color.)
- ISBN
- 9789811324475
- 9789811324468 (Print ed.)
- 9789811324482 (Print ed.)
- Specialty
- Laboratory Animal Science
- Abstract
- The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.
- This book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare.
- Contents
- 1. Zebrafish, Danio rerio as a replacement alternative model useful in CKDu experiments -- 2. Testing method development and validation for in vitro skin irritation testing (SIT) by using reconstructed human epidermis (RhE) skin equivalent: EPiTR -- 3. Development the technique for the preparation and characterization of reconstructed human epidermis (RHE) -- 4. Alternative research (3Rs) in the world, Asia and Japan -- 5. Approaches to reducing animal use for acute toxicity testing: Retrospective analyses of pesticide data -- 6. Progress in deleting the 1-year dog study for the safety assessment of pesticides -- 7. Cosmetic regulation and alternatives to animal experimentation in India -- 8. Guidance on the use of alternative test methods for the safety assessment of cosmetics and quasi-drugs -- 9. Alternatives and refinement for animal experimentation in cancer research -- 10. 3Rs in quality control of human vaccines: opportunities and barriers -- 11. The use of adverse outcome pathways (AOPs) to support chemical safety decisions within the context of integrated approaches to testing and assessment (IATA) -- 12. Mechanism-based evaluation system for hepato- and nephrotoxicity or carcinogenicity using omics technology -- 13. Alternative methods for developmental toxicity testing using mouse ESCs -- 14. Futuristic approach to alternative model organisms: hydra stakes its claim -- 15. The Lush Prize and Young Researcher Asia Awards 2016.
- Access
- Open access
- Format
- e-Book
- Publication Type
- Congress
- Location
- Online
Cadmium Toxicity : New Aspects in Human Disease, Rice Contamination, and Cytotoxicity
https://libcat.nshealth.ca/en/permalink/provcat44135
Seiichiro Himeno, Keiko Aoshima, editors.
--Singapore:
Springer
, 2019.
- Available Online
- View e-Book
- Location
- Online
This volume focuses on cadmium (Cd) exposure, its effects on human health, the mechanism of Cd accumulation and the development of mitigation technologies. Further, it discusses clinical, epidemiological, agricultural, toxicological, and biochemical aspects of Cd pollution and presents recent biochemical studies on molecular mechanisms of Cd cytotoxicity and cellular transport as well as the mechanism of Cd-induced disturbances in phosphorus (P) metabolism. It also provides insights into the pa…
- Available Online
- View e-Book
- Other Authors
- Himeno, Seiichiro
- Aoshima, Keiko
- Responsibility
- Seiichiro Himeno, Keiko Aoshima, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2019
- Physical Description
- 1 online resource (viii, 190 p.) : 68 illus., 51 illus. in color
- Series
- Current Topics in Environmental Health and Preventive Medicine
- ISBN
- 9789811336300
- 9789811336294 (Print ed.)
- 9789811336317 (Print ed.)
- ISSN
- 2364-8333
- Subjects (MeSH)
- Cadmium - toxicity
- Cadmium Poisoning
- Environmental Exposure
- Food Contamination - prevention & control
- Specialty
- Toxicology
- Abstract
- This volume focuses on cadmium (Cd) exposure, its effects on human health, the mechanism of Cd accumulation and the development of mitigation technologies. Further, it discusses clinical, epidemiological, agricultural, toxicological, and biochemical aspects of Cd pollution and presents recent biochemical studies on molecular mechanisms of Cd cytotoxicity and cellular transport as well as the mechanism of Cd-induced disturbances in phosphorus (P) metabolism. It also provides insights into the pathophysiology of itai-itai disease, a serious condition caused by Cd pollution. Cadmium: New Aspects in Human Disease, Rice Contamination, and Cytotoxicity is a valuable resource for scientists involved in heavy metal toxicology, botanical sciences, and regulatory sciences. Addressing the features of Cd pollution in the past and in the present, as well as future perspectives, this is a must-have book for students, researchers and practitioners interested in global and local metal pollution.
- Contents
- Part I. Overview -- 1. Historical Lessons on Cadmium Environmental Pollution Problems in Japan and Current Cadmium Exposure Situation -- Part II. Health Effects of Cadmium in Human Populations and its Relation to Cadmium Exposure Levels -- 2. Recent Clinical and Epidemiological Studies of Itai-Itai Disease (Cadmium-Induced Renal Tubular Osteomalacia) and Cadmium Nephropathy in the Jinzu River Basin in Toyama Prefecture, Japan -- 3. Novel Pathological Study of Cadmium Nephropathy of Itai-itai Disease -- 4. Long-Term Follow-Up Study of Residents Exposed to Cadmium in Kakehashi River Basin, Ishikawa, Japan -- 5. Effects of Cadmium Exposure on Life Prognosis -- 6. Cadmium Exposure and Its Effects on the Health Status of Rice Farmers in Akita Prefecture 7. Dietary Cadmium Intake Among General Populations in Japan and East Asia -- Part III. Rice Contamination by Cadmium and its Remediation -- 8. Regulations for Cadmium in Rice and Soil in Japan and Countermeasures to Reduce the Concentrations -- 9. Molecular Mechanism of Cadmium Accumulation in Rice - 10. Mitigation Strategies for Cadmium and Arsenic in Rice -- 11. Development of Low-Cadmium-Accumulating Rice -- Part IV. New Aspects in the Mechanisms of Cadmium Toxicity -- 12. Novel Mechanisms of Cadmium-Induced Toxicity in Renal Cells - 13. Roles of Metal Transporters in Cellular Cadmium Transport in Mammals -- 14. Disturbance in Phosphorus Metabolism by Cadmium Exposure.
- Format
- e-Book
- Location
- Online
Toxicities of Radiation Treatment for Breast Cancer : Risks and Management Strategies
https://libcat.nshealth.ca/en/permalink/provcat44269
Jean L. Wright, editor.
--Cham:
Springer
, 2019.
- Available Online
- View e-Book
- Location
- Online
This book is a comprehensive guide to breast toxicity. Adjuvant radiation remains standard for a majority of women who undergo breast-conserving surgery for breast cancer, and indications for post-mastectomy and regional lymph node irradiation have also broadened with recent publications. At the same time, locoregional recurrence has declined and survival has improved in recent decades. In the current era of excellent breast cancer outcomes, then, considering the balance between toxicity and ou…
- Available Online
- View e-Book
- Other Authors
- Wright, Jean L.
- Responsibility
- Jean L. Wright, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2019
- Physical Description
- 1 online resource (xii, 197 p.) : 15 illus., 12 illus. in color
- ISBN
- 9783030116200
- 9783030116194 (Print ed.)
- 9783030116217 (Print ed.)
- Subjects (MeSH)
- Breast Neoplasms - radiotherapy
- Health Physics
- Radiation Injuries
- Radiotherapy - adverse effects
- Risk Assessment
- Specialty
- Gynecology
- Medical Oncology
- Radiotherapy
- Toxicology
- Abstract
- This book is a comprehensive guide to breast toxicity. Adjuvant radiation remains standard for a majority of women who undergo breast-conserving surgery for breast cancer, and indications for post-mastectomy and regional lymph node irradiation have also broadened with recent publications. At the same time, locoregional recurrence has declined and survival has improved in recent decades. In the current era of excellent breast cancer outcomes, then, considering the balance between toxicity and outcomes becomes paramount. Several recent editorials recommend considering toxicity against the potential benefit of adjuvant radiation in tailoring radiation decisions for individual patients. Thus, a clear understanding of the potential toxicities of adjuvant radiation for breast cancer is critical to optimizing outcomes in modern breast cancer management. Here, authors have collected recent data focused on toxicity of treatment that provide an opportunity for improving this optimization. Chapters cover both acute and late toxicity of radiation for breast cancer, including tailored risk assessment for each of these potential toxicities, considerations for including risk of toxicity in management decisions, and toxicity management strategies. This is an ideal guide for radiation oncologists, residents, and oncologists seeking to optimize care for their patients.
- Contents
- 1. Including Toxicity Risk in Balanced Clinical Decision Making -- 2. Acute and Late Skin Toxicity from Breast Radiation -- 3. Fatigue Associated with Radiation Treatment for Breast Cancer -- 4. Pain Associated with Radiation Treatment for Breast Cancer -- 5. Considerations for Post-Mastectomy Radiation Therapy in the Setting of Breast Reconstruction -- 6. Lymphedema After Breast Cancer Treatment -- 7. Cardiotoxicity Associated with Radiation for Breast Cancer -- 8. Second Malignancies after Radiation for Breast Cancer -- 9. Tissue Fibrosis after Radiation Treatment for Breast Cancer -- 10. Pulmonary Toxicity Associated with Radiation Treatment for Breast Cancer -- 11. Integrative Methods for Management of Toxicities Associated with Radiation Treatment for Breast Cancer.
- Format
- e-Book
- Location
- Online
Maternal Drug Use and Infant Congenital Malformations
https://libcat.nshealth.ca/en/permalink/provcat44476
Bengt Källén.
--Cham:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
This book is the combination of the literature on maternal drug use and birth defects with a set of new data on most types of drugs. In this book, for each group of drugs the relevant scientific literature on drug teratogenicity is presented, with consideration of possible sources of error and also what the findings may mean from a practical point of view. The book also adds data from the Swedish health registers for 1996-2013 based on more than 1.7 million early-pregnancy midwife interviews. M…
- Available Online
- View e-Book
- Author
- Källén, Bengt
- Responsibility
- Bengt Källén
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xviii, 425 p.) : 16 illus. in color
- ISBN
- 9783030178987
- 9783030178970 (Print ed.)
- 9783030178994 (Print ed.)
- 9783030179007 (Print ed.)
- Subjects (MeSH)
- Abnormalities, Drug-Induced
- Fetus - drug effects
- Maternal-Fetal Exchange
- Pharmaceutical Preparations - adverse effects
- Specialty
- Embryology
- Toxicology
- Abstract
- This book is the combination of the literature on maternal drug use and birth defects with a set of new data on most types of drugs. In this book, for each group of drugs the relevant scientific literature on drug teratogenicity is presented, with consideration of possible sources of error and also what the findings may mean from a practical point of view. The book also adds data from the Swedish health registers for 1996-2013 based on more than 1.7 million early-pregnancy midwife interviews. Maternal Drug Use and Infant Congenital Malformations will find an engaged audience among people working within the field, and will be of interest to healthcare providers, especially obstetricians and other clinicians who treat women of childbearing age.
- Contents
- Background -- Maternal use of antacids or drugs for GERD and infant congenital malformations -- Maternal use of drugs for intestinal problems, except intestinal inflammations, and infant congenital malformations -- Maternal use of drugs for inflammatory intestinal disease and infant congenital malformations -- Maternal use of anti-obesity drugs and infant congenital malformations -- Maternal use of insulin or oral hypoglycemic drugs and infant congenital malformations -- Maternal use of vitamins and infant congenital malformations -- Maternal use of anticoagulants and hemostatic drugs and infant congenital malformations -- Maternal use of drugs for cardiovascular diseases and infant congenital malformations -- Maternal use of dermatological drugs and infant congenital malformations -- Maternal use of prolactin inhibitors or sex hormones and infant congenital malformations -- Maternal use of drugs for thyroid disease and infant congenital malformations -- Maternal systemic use of corticosteroids and infant congenital malformations -- Maternal use of hypophyseal or hypothalamic hormones and infant congenital malformations -- Maternal use of antibacterial or antifungal drugs and infant congenital malformations -- Maternal use of antiviral drugs, immunoglobulins, or vaccines and infant congenital malformations -- Maternal use of cytostatic/cytotoxic drugs or endocrine drugs used for malignancy and infant congenital malformations -- Maternal use of immunostimulating or immunosuppressive drugs and infant congenital malformations -- Maternal use of NSAID drugs and infant congenital malformations -- Maternal use of drugs other than NSAIDs for musculoskeletal diseases and infant congenital malformations -- Maternal use of opiates or opioid analgesics and infant congenital malformations -- Maternal use of mild analgesics and infant congenital malformations -- Maternal use of drugs for migraine and infant congenital malformations -- Maternal use of anticonvulsants and infant congenital malformations -- Maternal use of antipsychotics and infant congenital malformations -- Maternal use of sedatives or hypnotics and infant congenital malformations -- Maternal use of antidepressants and infant congenital malformations -- Maternal use of other psychoactive drugs and infant congenital malformations -- Maternal use of antiprotozoans, antihelminthics or insecticides and infant congenital malformations -- Maternal use of nasal decongestants, other nasal preparations, or throat preparations and infant congenital malformations -- Maternal use of anti-asthmatics and infant congenital malformations -- Maternal use of cough and common cold medicines and infant congenital malformations -- Maternal use of drugs for nausea and vomiting in pregnancy and infant congenital malformations -- Maternal use of antihistamine drugs for allergy and infant congenital malformations -- Maternal use of local eye and ear drug therapy and infant congenital malformations -- Maternal use of some groups of drugs with common side effects and infant congenital malformations -- The practical consequences of observed associations between the use of drug and infant congenital malformation.
- Format
- e-Book
- Location
- Online
Ophthalmology in Military and Civilian Casualty Care
https://libcat.nshealth.ca/en/permalink/provcat44670
Christopher J. Calvano, Robert W. Enzenauer, Anthony J. Johnson, editors.
--Cham:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
Trauma to the eye and associated structures account for a significant number of combat-related injuries, and combat ocular trauma has steadily risen in frequency over the last century. Ophthalmology in Military and Civilian Casualty Care comprehensively examines the accommodations and modifications that must be made in order to treat such ocular traumas in a military setting. Created by ophthalmology experts actively serving in the military at various levels, this book is designed to improve op…
- Available Online
- View e-Book
- Other Authors
- Calvano, Christopher J.
- Enzenauer, Robert W.
- Johnson, Anthony J.
- Responsibility
- Christopher J. Calvano, Robert W. Enzenauer, Anthony J. Johnson, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xiv, 278 p.) : 163 illus., 119 illus. in color
- ISBN
- 9783030144371
- 9783030144357 (Print ed.)
- 9783030144364 (Print ed.)
- Subjects (MeSH)
- Eye Injuries - therapy
- Military Medicine
- Specialty
- Disaster Medicine
- Military Medicine
- Ophthalmology
- Abstract
- Trauma to the eye and associated structures account for a significant number of combat-related injuries, and combat ocular trauma has steadily risen in frequency over the last century. Ophthalmology in Military and Civilian Casualty Care comprehensively examines the accommodations and modifications that must be made in order to treat such ocular traumas in a military setting. Created by ophthalmology experts actively serving in the military at various levels, this book is designed to improve ophthalmic casualty outcomes across military settings. A history of military ophthalmology serves as the opening chapter, setting the stage for subsequent chapters examining the intricacies and advancements of damage control ophthalmology, prehospital care of combat eye injuries, neuro-ophthalmic manifestations of trauma, and further severe ocular conditions. Later chapters explore the preventative and proactive efforts to reduce and treat combat-related ocular trauma by developing “eye armor” for the American infantry and military-affiliated ophthalmic surgical missions. Complete with high-quality color illustrations and figures, this unique book will serve as an invaluable, practical reference for military physicians, military ophthalmologists, ophthalmology professors, residents, and fellows interested in combat medicine and eye trauma.
- Contents
- Part I. Ophthalmic Considerations -- 1. History of Military Ophthalmology -- 2. Damage Control Ophthalmology -- 3. Damage Control Ophthalmology: Emergency Department Considerations -- 4. Damage Control Ophthalmology: Anesthesia Considerations -- 5. Diagnostic Imaging Considerations in Damage Control Ophthalmology -- 6. Damage Control Surgery: Blast—Anterior Segment Trauma -- 7. Posterior Segment -- 8. Traumatic Glaucoma -- 9. Periocular and Orbital Trauma -- 10. Neuro-Ophthalmic Manifestations of Trauma -- 11. Pediatric Ophthalmology -- 12. Uveitis -- Part II. Special Considerations -- 13. Prehospital Care of Combat Eye Injuries -- 14. Ocular Toxicology in Military and Civilian Disaster Environments -- 15. Winning the Hearts and Minds: Ophthalmology -- 16. Eye Armor -- 17. Humanitarian Missions -- Appendix: Suturing 101.
- Format
- e-Book
- Location
- Online
