This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer. Cancer is a disease of the chromosomes, and chromosomal instability in cancer disrupts gene function by either inactivating tumor suppressor genes or activating growth-promoting oncogenes. The chromosomal basis for these aberrations is either translocations, which chan…
For the first time, the world's experts in HIV-AIDS have come together to publish the Encyclopedia of AIDS. The work features over 4,000 A-Z entries including medical, cultural, social, and pharmacological essays. The Pathology entries cover the various types of HIV-related illnesses, including those that are and are not AIDS-defining. Many of the conditions that are AIDS-defining illnesses have their own entries or are cross-referenced to a generic entry in which several related conditions are…
Supported by figures, tables and photos, this book illustrates the basics of genetic diagnostics, prenatal and reproductive medicine, syndromology and familial cancers. It also includes numerous illustrated examples of the most frequent genetic diseases, making it a valuable resource in genetic counselling. This book is an essential tool for genetic counsellors, paediatricians, gynaecologists and all healthcare professionals who explain genetic issues to their patients. Useful also for teaching…
This volume provides a practical, comprehensive overview on benign and malignant disease of the adult kidney. The text addresses the topic of assessment and management of patients with surgical renal disease. Within this scope, it includes hereditary and spontaneous renal neoplasms, as well as non-neoplastic disease that manifests as a clinically relevant mass. The book is organized into chapters focusing on discrete disease entities and incorporating pathology, surgical management, oncologic t…
This text presents the application of current nutritional knowledge by physicians and incorporates emerging fields of science and important discoveries. Written by authors of international and national standing, leaders in the field and trendsetters, Arginine in Clinical Nutrition is essential reading for nutritionists and dietitians, public health scientists, doctors, epidemiologists, health care professionals of various disciplines, policy makers and marketing and economic strategists.
Sub- or preretinal hemorrhage involving the macula is a typical complication in a variety of ocular diseases, including age-related macular degeneration, arterial macroaneurysm, Valsalva retinopathy, and trauma. However, there is currently no consensus regarding the ideal treatment for macular hemorrhage. The purpose of this book on macular hemorrhage is twofold: it aims both to impart valuable information on pathophysiology, risk factors, diagnostic aspects, and prognostic criteria under diff…
Since publication of the first edition of this book in 2012 vitreoretinal surgery has marched with huge steps forward. In 2012 23G was standard, today 25G and 27G are the most commonly used gauge sizes for vitrectomy. In 2012 the cutting rate was 5.000 cuts/min and today with the development of a novel vitreous cutter the cutting rate has increased to 16.000 cuts/min. The advent of 25G/27G made the instruments smaller and surgery less traumatic. Practical Handbook for Small-Gauge Vitrectomy: A …
This new edition provides the latest information and insights into the molecular basis for lung cancer. Since the publication of the previous edition of this volume, dramatic changes have occurred with the classification of lung cancer, biomarker testing, and molecular therapy. The book covers these changes, providing updates and new insights on the background of lung cancer, testing methods, and the molecular pathology of specific cell types, including adenocarcinoma, squamous cell carcinoma, …
This book describes how different diagnostic techniques may facilitate the prenatal identification of orofacial malformations. The role of standard two-dimensional ultrasound is documented and explained, but detailed attention is also paid to the use of three-dimensional (3D) ultrasound, including the novel 3D reslicing technique, and to the value of complementary magnetic resonance imaging. The malformations considered include cleft lip, cleft lip and palate, ocular malformations, abnormalitie…
Rare Genitourinary Tumors offers the reader an up-to-date discussion of the less common neoplasms affecting the urinary tract and reproductive organs. Each authoritative chapter provides and in-depth discussion that is frequently not found in other urologic oncology textbooks. A valuable reference for urologists, oncologists, and those in specialty training, this volume provides ready access to information on etiology, incidence, risk factors, diagnosis, prognosis, insights from molecular patho…
This book aims to build concepts and create a solid foundation in the field of optical coherence tomography (OCT) for the general ophthalmologists as well as for the resident trainees and fellows. The chapters are written by leading international authorities in a style comprehensible to a broad audience. Numerous clinical pictures and SD-OCT scans help elucidate various clinical entities.OCT is the optical analog of ultrasound imaging and has emerged as a powerful imaging technique that enables…
This book addresses the most technically demanding cardiac surgical techniques, many of which are often performed on small infants. Conotruncal heart defects are a group of congenital anomalies of the cardiovascular system that are a leading cause of symptomatic cyanotic cardiac disease diagnosed in utero. Surgery of Conotruncal Anomalies provides a wealth of practical information and has been written by a collection of world renowned experts. They discuss the most challenging but life-changing…