This book reviews recent important advances in the use of optical coherence tomography (OCT) in order to analyze neurodegeneration within the retina through the quantification of axonal loss. Detailed information is provided on the role of OCT as a promising tool for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. The disorders considered include multiple sclerosis, Parkinson's disease, Alzheimer's disease, intracra…
The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading neuronal loss within the retina. Detailed information on the OCT imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. Covering disorders like multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, intracranial…
This guide surveys critical issues in therapeutic drug monitoring for non-toxicologists who want to gain greater insight into the unique requirements of special populations and learn how to avoid drug toxicity within a narrow therapeutic window.
New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration explores traumatic brain injury (TBI), a major cause of death and disability throughout the world. The delayed nature of the secondary injury phase suggests that there is a therapeutic window for pharmacological interventions or other approaches to prevent progressive tissue damage and improve functional outcomes. It is now apparent that therapeutic interventions should …
This book provides clinicians with state of the art information on the use of zygomatic implants to restore function and improve quality of life. International experts come together to showcase important innovations and advances in techniques that will assist in the optimization of outcomes. Readers will find information on indications, biomechanics, the role of imaging, digital treatment planning, and all aspects of implant placement. Individual chapters are devoted to different procedures, in…
This book focuses on uterine endometrial function and receptivity from multiple perspectives. The chapters cover a variety of topics including the role of estrogen and progesterone, animal models, parameters for assessing endometrial receptivity, the mechanism of angiogenesis, epigenetic regulation, and stem/progenitor cells. Despite nearly 35 years of experience with in vitro fertilization, the rate of successful implantations remains low. Abnormal endometrial receptivity has been proposed as …
Ovarian Stimulation Protocols is a concise handbook that aims to deliver everything the reader needs to know for performing a risk-free ovarian stimulation for assisted reproductive technique (ART) and get a favorable outcome. Review of crucial issues such as the significance of monitoring ovarian stimulation, advantages and disadvantages of ovarian hyperstimulation versus minimal stimulation, and the use of various drug regimens and stimulation protocols for various patient sub-sets, will help…
This book is the very first to cover the decompression theory in detail. It gives many information on all topics of the diving medicine, and is richly and uniquely illustrated. It offers a good guideline of high quality practice in diving medicine. The author provides a very structured and easy to understand book, by covering all aspects of the diving medicine, such as equipment, physiology, and related issues as gas intoxications, venomous animals or damages that can occur in the diving practi…
This atlas focuses on selected aspects of cochlear anatomy as illustrated by material prepared by the microdissection technique, a three-dimensional perspective not possible with standard histological approaches. Although much of the material in this text was processed by the microdissection method, photomicrographs from conventionally cross sectioned inner ear tissues and scanning electron microscopy, are also presented. Taken together, these technical approaches provide different, complementa…
Over the last decade the science and medicine of high altitude and hypoxia adaptation has seen great advances. High Altitude: Human Adaptation to Hypoxia addresses the challenges in dealing with the changes in human physiology and the particular medical conditions that arise from exposure to high altitude. In-depth and comprehensive chapters cover both the basic science and the clinical consequences of exposure to high altitude. Genetic, cellular, organ and whole body system responses to high a…
This Atlas is illustrated with rich pictures of cardiac surgical specimens. It not only contains normal heart specimens but also dissects those specimens, taking pictures from various angles to create a three-dimensional representation. It also includes reviews of the specimens' pathological reviews. Chapter 1 through 10 introduce the normal anatomy of the cardiac chambers and surgical approaches to the heart, while chapter 11 through 28 describe 18 kinds of congenital heart defects. There are …
This book clearly explains the basics of cranial ultrasonography in the neonate, from patient preparation through to screening strategies and the classification of abnormalities. The aim is to enable the reader consistently to obtain images of the highest quality and to interpret them correctly. Essential information is provided both on the procedure itself and on the normal ultrasound anatomy. The standard technique is described and illustrated, and emphasis is placed on the value of supplemen…
This atlas addresses the numerous changes and advances that have occurred in the field of congenital heart surgery over the last few years, resulting in improved techniques and new operations. The sheer number of new procedures and the required attendant technical skills to successfully complete an operation have become a challenge to master, especially for residents who are pursuing a career in congenital heart surgery. The atlas is organized generally by anomaly and the procedure pertaining t…
Childhood acute leukemias are one of the main causes of death in children aged 1 to 14 years in some countries; and unfortunately, we have been unable to prevent it. Certainly, a good parcel of it is due to the poor understanding about its etiology. This book aims to describe the most important theories and hypothesis regarding childhood acute leukemia. Written by the most outstanding researchers in the field, this book intends to contribute to a greater understanding of the etiology of this di…
This book covers the full range of Doppler echocardiography in infants and children, documenting the wide variety of potential findings with the aid of a wealth of high-quality images. The imaging features of more than 20 conditions on conventional two-dimensional echocardiography, pulsed wave, continuous wave and color Doppler imaging are described and depicted, drawing attention to differential diagnostic criteria and other issues of importance in everyday clinical practice. Each condition is…
Endocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole.Following initial evidence from basic research, endocrine disruption in humans has now emerged as a major medical …