yuji found 6 records - Provincial Hospitals Library Catalogue

Anesthesia and Neurotoxicity

https://libcat.nshealth.ca/en/permalink/provcat41914

Yuji Morimoto, editor. --Tokyo: Springer , 2017.

Available Online: View e-Book

Location: Online

This book, written by leading Japanese experts in the field, describes the latest findings on the neurotoxicity of anesthetics for the developing brain, postoperative delirium and cognitive dysfunction. It describes the risk factors for postoperative cognitive dysfunction in elderly surgical patients. Since the number of elderly patients undergoing surgery and anesthesia continues to increase, it is important to improve our understanding of the risks and mechanisms of postoperative delirium and…

Available Online: View e-Book

Other Authors: Morimoto, Yuji

Responsibility: Yuji Morimoto, editor

Place of Publication: Tokyo

Publisher: Springer

Date of Publication: 2017

Physical Description: 1 online resource (viii, 167 pages) : 15 illus., 11 illus. in color

ISBN: 9784431556244; 9784431556237 (print ed.)

Subjects (MeSH): Anesthesia - adverse effects; Brain - drug effects; Neurotoxicity Syndromes

Abstract: This book, written by leading Japanese experts in the field, describes the latest findings on the neurotoxicity of anesthetics for the developing brain, postoperative delirium and cognitive dysfunction. It describes the risk factors for postoperative cognitive dysfunction in elderly surgical patients. Since the number of elderly patients undergoing surgery and anesthesia continues to increase, it is important to improve our understanding of the risks and mechanisms of postoperative delirium and cognitive dysfunction, potential ways to prevent or alleviate them and the public health implications. Recently, it has been shown that using anesthetics on the developing brain causes apoptotic neurodegeneration and persistent learning/memory deficits later in life. Anesthesiologists need more information on this mechanism in the human brain. The negative effects of anesthesia and surgery on the nervous system have attracted attention lately; this book provides physicians, researchers, and postdocs with invaluable information on this topic.

Contents: Part I: Neurotoxicity of the Anesthetics for Developing Brain -- 1. Laboratory Findings: To What Degree Can We Extrapolate the Animal Data to the Bedside? -- 2. Clinical Findings Including Prevention and Treatment -- 3. Implications for Pediatric Anesthesia -- Part II: Postoperative Delirium and Cognitive Dysfunction -- 4. Present Clinical Status of Postoperative Delirium (POD) -- 5. Present Clinical Status of Postoperative Cognitive Dysfunction in Cardiovascular Surgery -- 6. Present Clinical Status of Postoperative Cognitive Dysfunction Following Non-Cardiac Surgery -- 7. Diagnosis of POD and POCD -- 8. Prevention and Treatment of Postoperative Delirium and Postoperative Cognitive Dysfunction -- 9. Mechanism of POD and POCD-Effect of Anesthetics -- 10. Mechanism of POCD and POCD-Effect of Other Than Anesthetics.

Format: e-Book

Location: Online

Personalized Pathway-Activated Systems Imaging in Oncology : Principal and Instrumentation

https://libcat.nshealth.ca/en/permalink/provcat41977

Tomio Inoue, David Yang, Gang Huang, editors. --Singapore: Springer , 2017.

Available Online: View e-Book

Location: Online

This comprehensive volume covers radiopharmaceuticals developed for pathway-directed systems in imaging and theranostic applications. We now are at the cutting edge of providing personalized treatment with increased use in oncology of these new radiopharmaceuticals. Trends in high-resolution instrumentation development, quality assurance systems and regulatory compliance for radiopharmaceuticals, clinical evaluation of radiopharmaceuticals, and benefits and pitfalls of the current clinical FDG …

Available Online: View e-Book

Other Authors: Inoue, Tomio; Yang, David; Huang, Gang

Responsibility: Tomio Inoue, David Yang, Gang Huang, editors

Place of Publication: Singapore

Publisher: Springer

Date of Publication: 2017

Physical Description: 1 online resource (xii, 243 pages) : 112 illus., 71 illus. in color

ISBN: 9789811033490; 9789811033483 (print ed.)

Subjects (MeSH): Neoplasms - diagnostic imaging; Positron Emission Tomography Computed Tomography - methods; Precision Medicine - methods; Radioactive Tracers; Radiopharmaceuticals

Abstract: This comprehensive volume covers radiopharmaceuticals developed for pathway-directed systems in imaging and theranostic applications. We now are at the cutting edge of providing personalized treatment with increased use in oncology of these new radiopharmaceuticals. Trends in high-resolution instrumentation development, quality assurance systems and regulatory compliance for radiopharmaceuticals, clinical evaluation of radiopharmaceuticals, and benefits and pitfalls of the current clinical FDG PET are discussed. Radiopharmaceuticals are used for diagnosis of diseases of the central nervous and cardiovascular systems and for staging, restaging, and treatment planning for cancers. Nuclear biomarkers allow precise measurement of molecular pathways on a whole-body image upon administration of functional radiolabeled agents, and nuclear imaging agents have potential use in patient selection, pharmacokinetic, dosage-finding, and proof-of-concept studies. Nuclear imaging agents and hybrid instrumentation also provide sensitive and specific answers for differential responsiveness in therapeutic outcome. This book serves as a reference for moving the discovery and development of radiopharmaceuticals from the workbench to clinical applications. It thus benefits not only clinicians but also translational research scientists, molecular biologists, chemists, imaging scientists, pharmaceutical developers, physicists, and support staff.

Contents: Part I: Chemical Biology Aspect -- Chapter 1: PET Radiotracers for Tumor Imaging (Ming Rong Zhang) -- Chapter 2. Theranostic tracers for pathway-activated systems in oncology (Lan V. Pham, Jerry L. Bryant, David Yang, and Richard J. Ford) -- Chapter 3. Optimization of Aseptic Production in PET Radiopharmaceuticals for Compliance to the Most Current GMP (Chih-Hao K. Kao) - Part II: Engineering and Instrumentation Aspect -- Chapter 4. OpenPET enabling PET imaging during radiotherapy (Taiga Yamaya and Hideaki Tashima) -- Chapter 5. High Resolution PET/CT development (Wai-Hoi Wong, and Yuxuan Zhang) -- Part III: Social Aspect -- Chapter 6. Ethics, Regulations and Clinical Development of Precision Medicine: Activating with molecular imaging (Chieko Kurihara, and Tomio Inoue) -- Chapter 7. Optical Imaging: How far can we go (Wenbin Ma, Sara Herrera-Rodriguez, and Hector Martinez-Valdez) -- Part IV: Clinic Aspect -- Chapter 8. Applications of UIH High Resolution PET/CT in Zhongshan Hospital (Jun Zhou, Hongcheng Shi) -- Chapter 9. Clinical evaluation of focused high-resolution breast PET (Kanae Kawai Miyake, Yuji Nakamoto) -- Chapter 10. Recent Developments with Large-bore PET/CT (Tomohiro Kaneta, Tomio Inoue) -- Chapter 11. Copper-labeled radiopharmaceuticals in oncology (Hiroaki Kurihara) -- Chapter 12. PET radiopharmaceuticals in oncology beyond FDG (Shao-Li Song, Pan-Li Li, Gang Huang) -- Chapter 13. Molecular Imaging in Oncology: Challenges and Opportunities in 21st Century (Ya-Ming Li, Ya-Ming Li, David J. Yang, and Xue-Na Li) -- Chapter 14. Visualization of Apoptosis: Annexin V imaging (Skye Hsin-Hsien Yeh, Fan-Lin Kong, Ming-Hsien Lin).

Format: e-Book

Location: Online

Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy

https://libcat.nshealth.ca/en/permalink/provcat40417

Yuji Kuge, Tohru Shiga, Nagara Tamaki, editors. --Tokyo: Springer Japan , c2016.

Available Online: View e-Book

Access: Open access

Location: Online

This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development. This anthology is based on the international symposium in 2015 entitled "Perspective on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy". The symposium provided an opportunity to exchange ideas on how to promote nuclear medicine technology and how to extend the technology to medica…

Available Online: View e-Book

Other Authors: Kuge, Yuji; Shiga, Tohru; Tamaki, Nagara

Other Authors: Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy (Symposium) (2015 : Sapporo : Japan)

Responsibility: Yuji Kuge, Tohru Shiga, Nagara Tamaki, editors

Place of Publication: Tokyo

Publisher: Springer Japan

Date of Publication: c2016

Physical Description: 1 online resource (xvi, 326 p. : 125 illus., 93 illus. in color)

ISBN: 9784431558941; 9784431558927 (print ed.)

Subjects (MeSH): Integrative Medicine; Molecular Diagnostic Techniques; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

Specialty: Radiology; Radiotherapy

Abstract: This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development. This anthology is based on the international symposium in 2015 entitled "Perspective on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy". The symposium provided an opportunity to exchange ideas on how to promote nuclear medicine technology and how to extend the technology to medical therapy and drug development, and was also a good opportunity to discuss the future perspective of nuclear medicine and molecular imaging by worldwide leaders in the field. Molecular imaging technologies have been rapidly developed worldwide in recent years. Among those developments, nuclear medicine has come to play an important role in quantitative analysis of biological process in vivo as well as in wide clinical use. With the current progress of nuclear medicine and molecular imaging, this modality has been applied for treatment monitoring and predicting its outcome with the use of optimal imaging biomarkers and suitable quantitative analysis. Truly, a new era has arrived with clinical use of nuclear medicine and molecular imaging for personalized medicine. This volume will benefit a wide variety of researchers in life science including those working in drug development, molecular imaging, and medical therapy as well as physicians who utilize diagnostic imaging.

Contents: Part I. Instrument and Data Analysis -- 1. Advances in 4D Gated Cardiac PET Imaging for Image Quality Improvement and Cardiac Motion and Contractility Estimation -- 2. The Need for Quantitative SPECT in Clinical Brain Examinations -- 3. PET Imaging Innovation by DOI Detectors -- 4. Semiconductor Detector-Based Scanners for Nuclear Medicine -- 5. Kinetic Analysis for Cardiac PET -- Part II. Biomarker and Molecular Probes -- 6. How Far Are We from Dose On Demand of Short-Lived Radiopharmaceuticals? -- 7 Advantages of Radiochemistry in Microliter Volumes -- 8. Development of a Microreactor for Synthesis of 18F-Labeled Positron Emission Tomography Probe -- 9 Preclinical Evaluation of a Thymidine Phosphorylase Imaging Probe, [123I]IIMU, for Translational Research -- 10. Discovery and Evaluation of Biomarkers for Atherosclerosis -- 11. Radioimmunodetection of Atherosclerotic Lesions Focusing on the Accumulation Mechanism of Immunoglobulin G -- Part III. Cardiology -- 12 Noninvasive PET Flow Reserve Imaging to Direct Optimal Therapies for Myocardial Ischemia -- 13. The Clinical Value of Cardiac PET in Heart Failure -- 14. Emerging Trends and Future Perspective of Novel Cardiac SPECT Technology -- 15. Right Ventricular Metabolism and Its Efficiency -- 16. Usefulness of 18F-FDG PET in Diagnosing Cardiac Sarcoidosis -- Part IV. Neurology -- 17. PET Quantification in Molecular Brain Imaging Taking into Account the Contribution of the Radiometabolite Entering the Brain -- 18. Hypoxia Imaging with 18F-FMISO PET for Brain Tumors -- 19. Evolution and Protection of Cerebral Infarction Evaluated by PET and SPECT -- 20. Brain Development and Aging Using Large Brain MRI Database -- Part V. Oncology -- 21. Back to the Future: Nuclear Medicine Rediscovers Its Therapeutic Roots -- 22. Interactive Communication Between PET Specialists and Oncologists -- 23. Clinical Efficacy of PET/CT Using 68Ga-DOTATOC for Diagnostic Imaging -- 24. Correlation of 40-[methyl-11C]-Thiothymidine Uptake with Ki-67 Immunohistochemistry in Patients with Newly Diagnosed and Recurrent Gliomas -- 25. Impact of Respiratory-Gated FMISO-PET/CT for the Quantitative Evaluation of Hypoxia in Non-small Cell Lung Cancer.

Access: Open access

Format: e-Book

Location: Online

Practical handbook of advanced interventional cardiology

https://libcat.nshealth.ca/en/permalink/provcat30720

(4th ed.) --Chichester, West Sussex, UK: Wiley-Blackwell , c2013.

Available Online: View e-Book

Location: Online

Available Online: View e-Book

Other Authors: Nguyen, Thach

Edition: 4th ed.

Place of Publication: Chichester, West Sussex, UK

Publisher: Wiley-Blackwell

Date of Publication: c2013

Physical Description: 686 p.

ISBN: 9780470670477 (pbk.)

Subjects (MeSH): Cardiovascular Surgical Procedures - methods; Cardiovascular Diseases - surgery; Handbooks

Contents: Vascular access / Thach N. Nguyen, Dominic Nguyen, and Quoc Nguyen -- Angiographic views / Thach N. Nguyen, Kim Sui Hian, and Timothy J. Yee -- Guides / Dobrin Vassilev and Thach N. Nguyen -- Wires / Dobrin Vasilev ... [et al.] -- Balloon angioplasty / Thach N. Nguyen, Tung Mai, and Dominic Nguyen -- Stenting / Thach N. Nguyen ... [et al.] -- Transradial approach / Shigeru Saito ... [et al.] -- Slender transradial intervention / Yuji Ikari -- Left main / Runlin Gao, Xu Bo, and Thach Nguyen -- Chronic total occlusion / Etsuo Tsuchikane ... [et al.] -- Ostial lesions / Szabolcs Szabo and Thach N. Nguyen -- Acute ST segment elevation myocardial infarction / Marko Noc ... [et al.] -- Interventions in patients after coronary artery bypass graft surgery / Thach N. Nguyen, Nguyen Quang Tuan, and Muhammad Munawar -- Bifurcation lesion / Shao Liang ... [et al.] -- Complications / Asok Seth, Nguyen Ngoc Quang, and Thach Nguyen -- High risk patients / Ramesh Daggubati ... [et al.] -- Removal of embolized material / Thach N. Nguyen ... [et al.] -- Inoue-balloon mitral valvuloplasty / Jui-Sung Hung and Kean-Wah Lau -- Retrograde percutaneous aortic valvuloplasty / Ted Feldman and Thach N. Nguyen -- Percutaneous implantation of aortic valvular prostheses / Stefan Toggweiler and John Webb -- Subclavian artery interventions / Gianluca Rigatelli, Paolo Cardaioli, and Aravinda Nanjundappa -- Endovascular repair of abdominal aortic aneurysm / Aravinda Nanjundappa, Damras Tresukosol, and Thach N. Nguyen -- Renal artery interventions / Gianluca Rigatelli and Paolo Cardaioli -- Carotid artery occlusive disease / Gianluca Rigatelli, Paolo Cardaioli, and Horst Sievert -- Iliac artery stenosis / Timothy C. Dy ... [et al.] -- Infrainguinal and infragenicular interventions / Jasrai Gill ... [et al.] -- Percutaneous intervention of cardiac congenital anomalies / Gianluca Rigatelli, Zhang Shuang Chuan, and Nguyen Lan Hieu