Metastatic Bone Disease : An Integrated Approach to Patient Care
https://libcat.nshealth.ca/en/permalink/provcat39684
R. Lor Randall, editor.
(1st ed.)
--New York, NY:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and b…
- Available Online
- View e-Book
- Other Authors
- Randall, R. Lor
- Responsibility
- R. Lor Randall, editor
- Edition
- 1st ed.
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xiii, 368 p. : 85 illus., 35 illus. in color)
- ISBN
- 9781461456629
- 9781461456612 (print ed.)
- Subjects (MeSH)
- Bone Neoplasms - secondary
- Bone Neoplasms - therapy
- Abstract
- Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and biotargeting. The heart of the book presents oncological approaches (supportive, radiation, and interventional) and principles of orthopedic surgical oncology, with subsequent chapters covering specific anatomy, from the pelvis to the lower extremity and the spine. Chapters on emerging surgical technology and future directions conclude the text and redefine an integrated approach to patient care. Taken together, Metastatic Bone Disease is an excellent resource for orthopedic surgeons and cancer specialists alike.
- Contents
- Part I. The Problem -- Bone Metastases: Epidemiology and Societal Effect -- Part II. Biology of Metastases and Tissue of Origin Considerations -- Pathobiology of Osteolytic and Osteoblastic Bone Metastases -- Biology of Bone Cancer Pain -- Breast Cancer Bone Metastases -- Prostate Cancer Bone Metastasis -- Lung -- Kidney Metastatic Bone Disease -- Thyroid -- Myeloma -- Part III. Work-Up for Patients with Suspected Metastatic Bone Disease -- Evaluation of the Patient with Carcinoma of Unknown Origin Metastatic to Bone -- Biopsy Considerations -- Part IV. Medical Therapy -- Bisphosphonates, Denosumab and Anabolic Agents in the Treatment of Metastatic Bone Disease -- Biotargeting in Metastatic Bone Disease -- Part V. Supportive Oncology -- Psychosocial Considerations for Patients with Metastatic Bone Disease -- Pain Management in Metastatic Bone Disease -- When is Hospice Appropriate? The Role for Hospice in Palliating Patients with Bone Metastases -- Part VI. Radiation Oncology -- Current and Emerging Modalities -- Part VII. Interventional Oncology -- Ablation and Cementation Technologies -- Part VIII. Principles of Orthopaedic Surgical Oncology -- Issues Facing the Established Metastatic Bone Disease Patient, Timing/Indications for Surgery -- Questions to Ask Your Medical Oncology Colleagues -- Consideration of the Temporal Relationship between Surgery and Radiation Therapy -- Role of Surgery in Oligometastatic Disease -- Part IX. Specific Anatomic Considerations for Surgery -- Metastatic Bone Disease: Pelvis -- Metastatic Bone Disease: Femur -- Metastatic Bone Disease: Femur: Tibia -- Metastatic Bone Disease: Foot -- Metastatic Bone Disease: Femur: Humerus, Scapula -- Metastatic Bone Disease: Forearm, Hand -- Metastatic Bone Disease: Spine -- Part X. Emerging Surgical Technologies -- Intraoperative Imaging and Navigation -- Part Eleven: Putting It All Together -- Integrative Approach with the Patient in Mind: A Glance Forward.
- Format
- e-Book
- Location
- Online
