Print - Provincial Hospitals Library Catalogue

Translational Pancreatic Cancer Research : From Understanding of Mechanisms to Novel Clinical Trials

https://libcat.nshealth.ca/en/permalink/provcat45203

Christoph W. Michalski, Jonas Rosendahl, Patrick Michl, Jörg Kleeff, editors. --Cham: Humana Press , c2020.

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Location: Online

This book incorporates a multi-disciplinary approach to present how research results can be translated into clinical trials. The first part begins with a chapter on variants of pancreatic cancer, precursor lesions and groups of people at risk to developing the disease. There is a particular focus on intraductal papillary mucinous neoplasia as a large-scale clinical challenge in pancreatology. The next two parts focus on diagnosis, biomarkers and stratification that emphasize how various approac…

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Other Authors: Michalski, Christoph W.; Rosendahl, Jonas; Michl, Patrick; Kleeff, Jörg

Responsibility: Christoph W. Michalski, Jonas Rosendahl, Patrick Michl, Jörg Kleeff, editors

Place of Publication: Cham

Publisher: Humana Press

Date of Publication: c2020

Physical Description: 1 online resource (xii, 245 p.) : 18 illus., 17 illus. in color

Series Title: Molecular and translational medicine

ISBN: 9783030494766; 9783030494759 (Print ed.); 9783030494773 (Print ed.); 9783030494780 (Print ed.)

ISSN: 2197-7852

Subjects (MeSH): Biomarkers, Tumor; Pancreatic Neoplasms - therapy; Translational Medical Research

Specialty: Medical Oncology; Pathology

Abstract: This book incorporates a multi-disciplinary approach to present how research results can be translated into clinical trials. The first part begins with a chapter on variants of pancreatic cancer, precursor lesions and groups of people at risk to developing the disease. There is a particular focus on intraductal papillary mucinous neoplasia as a large-scale clinical challenge in pancreatology. The next two parts focus on diagnosis, biomarkers and stratification that emphasize how various approaches to biomarker development are important as both prognostic and predictive tools. The final part consists of personalized treatment approaches that include preclinical models of pancreatic cancer and stromal, epigenetic and metabolism targeting as promising approaches to be translated into early phase clinical trials. Chapters within this part also deal with approaches that are close to being implemented in clinical practice or are already being tested in (early) clinical trials, such as those that targeting the immune systems and strategies to overcome immunotherapy resistance; phase 1 clinical trials and translational approaches in surgical treatment. Written by experts in their fields, Translational Pancreatic Cancer Research provides an outlook towards future directions by integrating information both from basic and clinical research and though demonstrating pathways to better understanding pancreatic cancer and current approaches to translating these into clinical practice.

Contents: Part I. PDAC Variants and Risk of Disease -- Subtypes of Pancreatic Adenocarcinoma -- Part II. PDAC Precursors and Early Diagnosis -- Surveillance and Intervention in IPMN -- Novel Biomarkers of Invasive IPMN -- Part III. Diagnosis, Biomarkers and Stratification -- Challenges and Opportunities for Early Pancreatic Cancer Detection: Role for protein biomarkers -- Metabolic Biomarkers of Pancreatic Cancer -- Blood-Based Circulating RNAs as Preventive, Diagnostic, Prognostic and Drugable Biomarkers for Pancreatic Ductal Adenocarcinoma -- Circulating tumor DNA as a novel biomarker for pancreatic cancer -- PDAC Subtypes/Stratification -- Circulating Tumor Cells as Biomarkers in Pancreatic Cancer -- Part IV. Personalized Treatment Approaches -- Personalized Models of Human PDAC -- Therapeutic Targeting of Stromal Components -- Epigenetic Targeting -- Targeting Metabolism -- Targeting the Immune System in Pancreatic Cancer -- Phase I Trials in Pancreatic Cancer -- Translational Approaches in Surgical Treatment.

Format: e-Book

Location: Online

The Washington manual of medical therapeutics

https://libcat.nshealth.ca/en/permalink/provcat32678

editors, Zachary Crees ... [et al.]. (36th ed.) --Philadelpha, PA: Wolters Kluwer , c2020.

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Location: Online

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Corporate Author: Washington University Department of Medicine

Other Authors: Crees, Zachary; Fritz, Cassandra; Heudebert, Alonso; Noé, Jonas; Rengarajan, Arvind; Wang, Xiaowen

Responsibility: editors, Zachary Crees ... [et al.]

Edition: 36th ed.

Place of Publication: Philadelpha, PA

Publisher: Wolters Kluwer

Date of Publication: c2020

Physical Description: [954 p.]

ISBN: 9781975113513 (pbk.); 9781975113483 (e-ISBN)

Subjects (MeSH): Therapeutics

Specialty: Clinical Medicine

Contents: 1. Patient Care in Internal Medicine -- 2. Nutrition Support -- 3. Preventive Cardiology -- 4. Ischemic Heart Disease -- 5. Heart Failure and Cardiomyopathy -- 6. Pericardial and Valvular Heart Disease -- 7. Cardiac Arrhythmias -- 8. Critical Care -- 9. Obstructive Lung Disease -- 10. Pulmonary Diseases -- 11. Allergy and Immunology -- 12. Fluid and Electrolyte Management -- 13. Renal Diseases -- 14. Treatment of Infectious Diseases -- 15. Antimicrobials -- 16. Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome -- 17. Solid Organ Transplant Medicine -- 18. Gastrointestinal Diseases -- 19. Liver Diseases -- 20. Disorders of Hemostasis and Thrombosis -- 21. Hematologic Disorders and Transfusion Therapy -- 22. Medical Management of Malignant Disease -- 23. Diabetes Mellitus and Related Disorders -- 24. Endocrine Diseases -- 25. Arthritis and Rheumatologic Diseases -- 26. Neurologic Disorders -- 27. Medical Emergencies -- 28. Toxicology -- Appendix A. Immunizations and Postexposure Therapies -- Appendix B. Infection Control and Isolation Recommendations -- Appendix C. Advanced Cardiac Life Support Algorithms -- Index.

Format: e-Book

Publication Type: Handbook

Location: Online

Advanced Techniques in Shoulder Arthroscopy

https://libcat.nshealth.ca/en/permalink/provcat44768

Peter J. Millett, Jonas Pogorzelski, editors. --Cham: Springer , c2019.

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Location: Online

This book is written for the benefit of all surgeons who have an interest in arthroscopic shoulder surgery. It is a compendium of different aspects of shoulder surgery that have been learned over the last 25 years. While there has been a rapid progression of shoulder surgery over the last two decades, particularly with the advancement of operative arthroscopic surgery, certain principles remain. The purpose of this book is not to be an exhaustive detailed account of the various historical aspec…

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Other Authors: Millett, Peter J.; Pogorzelski, Jonas

Responsibility: Peter J. Millett, Jonas Pogorzelski, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2019

Physical Description: 1 online resource (xii, 267 p.) : 214 illus., 207 illus. in color

ISBN: 9783030135034; 9783030135027 (Print ed.); 9783030135041 (Print ed.); 9783030135058 (Print ed.)

Subjects (MeSH): Arthroscopes; Arthroscopy - methods; Shoulder Joint - surgery

Subjects (LCSH): Orthopedics

Specialty: Orthopedic Procedures

Abstract: This book is written for the benefit of all surgeons who have an interest in arthroscopic shoulder surgery. It is a compendium of different aspects of shoulder surgery that have been learned over the last 25 years. While there has been a rapid progression of shoulder surgery over the last two decades, particularly with the advancement of operative arthroscopic surgery, certain principles remain. The purpose of this book is not to be an exhaustive detailed account of the various historical aspects of arthroscopic shoulder surgery, but rather to act as an up-to-date, instructional handbook that outlines these principles. The book also helps the practicing shoulder surgeon become familiar some of the latest techniques in arthroscopic shoulder surgery, demonstrating proven approaches and outlining key aspects of common and uncommon procedures. Each chapter starts with the indications for the procedure, moves towards the appropriate evaluation and diagnostic work up, and culminates in specific technical explanation of the surgical procedure itself. Advanced Techniques in Shoulder Arthroscopy is a valuable resource for those who are new to arthroscopic shoulder surgery and for those who are skilled and experienced in operative arthroscopy. It is meant to provide a foundation for basic and advanced arthroscopic techniques that helps surgeons improve their craft and treat their patients better.

Contents: Part I. How to Start -- 1. Patient Positioning, Portals, Fluid Management, and Diagnostic Arthroscopy -- Part II. Rotator Cuff Tears -- 2. Subacromial Decompression -- 3. Subscapularis Repair -- 4. Postero-superior Rotator Cuff Tears -- 5. Repair with Patch Augmentation -- 6. Latissimus Dorsi Transfer with Patch Augmentation -- 7. Arthroscopic Superior Capsule Reconstruction -- 8. Pectoralis Major Tendon Transfer for Irreparable Subscapularis Tears -- 9. Anterior Capsule Reconstruction -- Part III. Glenohumeral Instability -- 10. Anterior Instability Without Bone Loss: Bankart Repair -- 11. Anterior Instability with Bone Avulsion: Bony Bankart Bridge Procedure -- 12. Anterior Instability: Arthroscopic HAGL Repair -- 13. Anterior Instability with Bone Loss: Latarjet Procedure -- 14. Pancapsular Shift for Multidirectional Instability -- 15. Posterior Instability -- Part IV. Biceps Tendon Pathologies -- 16. Proximal Biceps Pathologies: SLAP Lesions, Pulley Lesions, and Biceps Tenosynovitis -- Part V. Sternoclavicular and Acromioclavicular Joint Pathologies -- 17. Treatment of Sternoclavicular Joint Arthritis -- 18. Treatment of Sternoclavicular Joint Instability -- 19. Treatment of Acromioclavicular Joint Arthritis -- 20. Treatment of Acromioclavicular Joint Separation -- Part VI. Glenohumeral Osteoarthritis -- 21. Comprehensive Arthroscopic Management of Glenohumeral Osteoarthritis (CAM Procedure) -- Part VII. Additional Pathologies and Procedures -- 22. Arthrolysis: Capsular Release for Adhesive Capsulitis -- 23. Neurolysis of the Suprascapular Nerve -- 24. Scapulothoracic Bursectomy -- 25. Pectoralis Major Repair -- 26. Pectoralis Minor Tenotomy.

Format: e-Book

Location: Online

Cardio-renal clinical challenges

https://libcat.nshealth.ca/en/permalink/provcat33624

David Goldsmith, Adrian Covic, Jonas Spaak, editors. --Cham, Switzerland: Springer , c2015.

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Location: Online

This book provides a comprehensive overview of the clinical challenges faced during the treatment of patients with cardiorenal syndrome (CRS). The bidirectional link that associates renal and cardiovascular diseases means that patients with CRS have an increased risk of hospital admission and mortality as a result of their coexistence yet, there are no agreed guidelines for their management. Cardio-Renal Clinical Challenges takes clinical presentations and clinical problems as its base, and the…

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Other Authors: Goldsmith, David; Covic, Adrian; Spaak, Jonas

Responsibility: David Goldsmith, Adrian Covic, Jonas Spaak, editors

Place of Publication: Cham, Switzerland

Publisher: Springer

Date of Publication: c2015

Physical Description: 1 online resource (xiii, 234 pages)

ISBN: 9783319091624 (electronic bk.); 9783319091617

Subjects (MeSH): Cardiovascular Diseases - complications; Renal Insufficiency, Chronic - complications; Comorbidity

Subjects (LCSH): Cardiovascular system - Diseases; Kidneys - Diseases; Heart - Diseases

Abstract: This book provides a comprehensive overview of the clinical challenges faced during the treatment of patients with cardiorenal syndrome (CRS). The bidirectional link that associates renal and cardiovascular diseases means that patients with CRS have an increased risk of hospital admission and mortality as a result of their coexistence yet, there are no agreed guidelines for their management. Cardio-Renal Clinical Challenges takes clinical presentations and clinical problems as its base, and then discusses the evidence for best management of common clinical problems and the reasons for the complex interplay between the cardiac and renal systems. In addition, the link between heart failure and chronic kidney disease (CKD) can impose a considerable epidemiological burden thus this text also aims to address the issue of organizing healthcare to maximize both the opportunities for prevention and best healthcare economic returns.

Contents: Part I. Cardiovascular Disease (CVD) in Chronic Kidney Disease (CKD): Same or Different? -- 1. Epicardial Coronary Heart Disease in CKD: Diagnosis and Management -- 2. Small Vessel Disease in CKD, Diabetes, Obesity and Hypertension -- 3. Sudden Cardiac Death and Arrhythmia in CKD -- 4. Anticoagulation in CKD -- 5. MRA Inhibition in CKD: More Than Salt and Water -- 6. Vascular Effects of Infl ammation and Oxidative Stress in CKD -- 7. Uric Acid, Allopurinol: The Cardio- Renal Silver Bullet? -- 8. FGF23 and Phosphate: Two Cardiovascular Toxins with Distinct Toxicity Profiles? -- 9. Renal Congestion in Heart Failure -- 10. Effect of Vitamin D on Endothelial Function and Blood Pressure -- 11. Vitamin D and Its Effects on the Heart -- Part II. CKD Complicating Cardiovascular Presentations, Treatment and Outcome -- 12. Volume Overload in CKD: Pathophysiology, Assessment Techniques, Consequences and Treatment -- 13. Reversing Arterial Stiffening and Calcifi cation: A Pipe Dream? -- 14. Pulmonary Hypertension in CKD: A New Problem Child -- 15. How to Use Inhibitors of the Renin-Angiotensin- Aldosterone System in Patients with CKD and Heart Failure -- 16. Erectile and Sex Hormone Dysfunction and Cardiovascular Consequences in CKD -- 17. Renal Sympathetic Denervation in the Management of Treatment- Resistant Hypertension -- Part III. New Ways of Working for the Twenty-first Century: Rising to the Challenge of Comorbid Patients -- 18. Future Therapeutic Prospects for Treatment of Cardiorenal Syndromes -- 19. Novel Combination Therapy to Target Heart and Kidney -- 20. Challenging Complex Diseases -- 21. Is “Me, Me, Me” the New “We, We, We”?: Can We Afford (Not) to Take the Plunge into the Personalised, Stratified Medicine Era? -- 22. Psychological Distress in Physical Long-Term Conditions.

Format: e-Book

Location: Online

Positron Emission Tomography with Computed Tomography (PET/CT)

https://libcat.nshealth.ca/en/permalink/provcat39054

Jonas Francisco Y. Santiago. --Cham: Springer , c2015.

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Location: Online

Positron Emission Tomography with Computed Tomography (PET/CT) is an accessible case book presenting interesting cases encountered by the author over the last ten years experience as the chairman and director of the only PET Center in the Philippines. It aims to guide physicians in the accurate interpretation of the PET scans of uncommon diseases, and sometimes common cases but in extraordinary situations or conditions. Encompassing a wide and varied range of fields such as oncology, inflammato…

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Author: Santiago, Jonas Francisco Y

Responsibility: Jonas Francisco Y. Santiago

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2015

Physical Description: 1 online resource (xv, 125 p. : 119 illus., 94 illus. in color)

ISBN: 9783319055183; 9783319055176 (print ed.)

Subjects (MeSH): Positron-Emission Tomography; Tomography, X-Ray Computed

Abstract: Positron Emission Tomography with Computed Tomography (PET/CT) is an accessible case book presenting interesting cases encountered by the author over the last ten years experience as the chairman and director of the only PET Center in the Philippines. It aims to guide physicians in the accurate interpretation of the PET scans of uncommon diseases, and sometimes common cases but in extraordinary situations or conditions. Encompassing a wide and varied range of fields such as oncology, inflammatory, immunology, anatomic variants etc., Positron Emission Tomography with Computed Tomography (PET/CT) will help those beginning their practice, and may even be useful to veterans of the field whose scope of practice has been limited to more common indications of an FDG-PET scan.

Contents: 1. Introduction -- 2. Brain -- 3. Diagnosed by PET -- 4. Tuberculosis -- 5. Inflammation -- 6. Rare or Unusual Primary Malignancies -- 7. Unusual Metastatic Sites -- 8. Missed in PET -- 9. Anatomical and Physiological Variants -- 10. Unconventional Imaging Techniques.

Format: e-Book

Publication Type: Case Reports

Location: Online

Handbook of renal and pancreatic transplantation

https://libcat.nshealth.ca/en/permalink/provcat25716

--Chichester, West Sussex, UK: Wiley-Blackwell , 2012.

Call Number: WJ 368 H236 2012

Location: Dickson Building

Call Number: WJ 368 H236 2012

Other Authors: MacPhee, Iain A; Fronek, Jiri

Place of Publication: Chichester, West Sussex, UK

Publisher: Wiley-Blackwell

Date of Publication: 2012

Physical Description: 481 p.

ISBN: 9780470654910

Subjects (MeSH): Kidney Transplantation; Pancreas Transplantation

Contents: History of transplantation / Ji Fronk and Iain A.M. MacPhee -- Assessment of the potential renal transplant recipient / Alan G. Jardine and Patrick B Mark -- Pre-transplant assessment and medical evaluation of potential live kidney donors / Jonas Wadstrm -- Histocompatibility and immunogenetics / Susan V. Fuggle and Craig J. Taylor -- Donor management : the care of the heart beating brain dead multi-organ donor / Paul G. Murphy -- Deceased donor retrieval / Albert M. Wolthuis ... [et al.] -- Live donor nephrectomy / Ji Fronk and Nicos Kessaris -- Organisation of transplant services, organ sharing, and organ allocation : a perspective from the UK and Eurotransplant / James Neuberger and Axel Rahmel -- Deceased donor kidney transplantation / Luisa Berardinelli -- Living donor kidney transplantation / Ji Fronk -- Pancreas transplantation / Guido Woeste and Wolf O. Bechstein -- Pancreatic islet transplantation / Frantisek Saudek -- Anaesthesia for renal transplantation / Nicoletta Fossati -- Anaesthesia for pancreatic transplantation / Kai Zacharowski and Hans-Joachim Wilke -- Anaesthesia for live donor nephrectomy / Rehana Iqbal -- Immunosuppression / Iain A.M. MacPhee and Teun van Gelder -- Antibody removal / Nicos Kessaris and Nizam Mamode -- Paediatric transplantation / Luisa Berardinelli and Luciana Ghio -- Post-transplant diagnostic imaging / Lakshmi Ratnam and Uday Patel -- Transplant histopathology / Eva Honsova -- Infection / Rachel Hilton and Martin W. Drage -- Management during the first three months after transplantation / Iain A.M. MacPhee, Joyce Popoola, and Daniel Jones -- Management of long-term complications / Paul N. Harden ... [et al.] -- Living donor follow-up / Ji Fronk and Robert Elias -- Ethics of transplantation / Robert Elias and Rehana Iqbal.

Format: Book

Location: Dickson Building

Loan Period: 3 weeks

Viral Hepatitis in Children : Unique Features and Opportunities

https://libcat.nshealth.ca/en/permalink/provcat29399

edited by Maureen M. Jonas. --Totowa, NJ: Springer Science+Business Media , c2010.

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Location: Online

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Author: Jonas, Maureen M

Responsibility: edited by Maureen M. Jonas

Place of Publication: Totowa, NJ

Publisher: Springer Science+Business Media

Date of Publication: c2010

Series Title: Clinical gastroenterology

ISBN: 9781607613732

Subjects (MeSH): Hepatitis, Viral, Human - Child

Subjects (LCSH): Gastroenterology; Pediatrics; Infectious diseases; Hepatology

Specialty: Gastroenterology; Pediatrics; Virology

Format: e-Book

Location: Online

Tracheotomy : airway management, communication, and swallowing

https://libcat.nshealth.ca/en/permalink/provcat23335

Myers, Eugene N. (2nd ed.) --San Diego, CA: Plural Publishing , 2008.

Call Number: WF 490 T759 2008

Location: Halifax Infirmary

Call Number: WF 490 T759 2008

Author: Myers, Eugene N

Other Authors: Johnson, Jonas T

Edition: 2nd ed.

Place of Publication: San Diego, CA

Publisher: Plural Publishing

Date of Publication: 2008

Physical Description: 238 p.

ISBN: 9781597561013

Subjects (MeSH): Tracheotomy; Tracheostomy

Format: Book

Location: Halifax Infirmary

Loan Period: 3 weeks

The ABCs of human behavior : behavioral principles for the practicing clinician

https://libcat.nshealth.ca/en/permalink/provcat23596

Ramnero, Jonas. --Oakland, CA: New Harbinger Publications , 2008.

Call Number: WM 105 R174a 2008

Location: Halifax Infirmary

Call Number: WM 105 R174a 2008

Author: Ramnero, Jonas

Other Authors: Torneke, Niklas

Place of Publication: Oakland, CA

Publisher: New Harbinger Publications

Date of Publication: 2008

Physical Description: 214 p.

ISBN: 9781572245389

Subjects (MeSH): Behavior Therapy - methods; Psychology, Clinical - methods; Conditioning, Operant; Learning

Format: Book

Location: Halifax Infirmary

Loan Period: 3 weeks

Evidence-Based Otolaryngology

https://libcat.nshealth.ca/en/permalink/provcat29355

edited by Jennifer J. Shin, Christopher J. Hartnick, Gregory W. Randolph, Michael J. Cunningham, Margaret Kenna, J. Paul Willging, Joseph B. Nadol, Steven D. Rauch, Jay F. Piccirillo, Gregory W. Randolph, Jonas T. Johnson, Gregory W. Randolph. --New York, NY: Springer-Verlag , c2008.

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Location: Online

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Author: Shin, Jennifer J

Other Authors: Hartnick, Christopher J; Randolph, Gregory W; Cunningham, Michael J; Kenna, Margaret; Willging, J. Paul; Nadol, Joseph B; Rauch, Steven D; Piccirillo, Jay F; Johnson, Jonas T

Responsibility: edited by Jennifer J. Shin, Christopher J. Hartnick, Gregory W. Randolph, Michael J. Cunningham, Margaret Kenna, J. Paul Willging, Joseph B. Nadol, Steven D. Rauch, Jay F. Piccirillo, Gregory W. Randolph, Jonas T. Johnson, Gregory W. Randolph