Atlas of sleep medicine

https://libcat.nshealth.ca/en/permalink/provcat31323
Sudhansu Chokroverty, Robert J. Thomas. (2nd ed.) --Philadelphia, PA: Elsevier Saunders , c2014.
Available Online
View e-Book
Location
Online
Available Online
View e-Book
Author
Chokroverty, Sudhansu
Other Authors
Thomas, Robert J
Responsibility
Sudhansu Chokroverty, Robert J. Thomas
Edition
2nd ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Date of Publication
c2014
Physical Description
1 online resource (xiii, 387 p.)
ISBN
9781455712687
Subjects (MeSH)
Polysomnography - Atlases
Sleep Wake Disorders - diagnosis - Atlases
Contents
Polysomnographic recording technique / Sudhansu Chokroverty and Sushanth Bhat -- Electroencephalography for the sleep specialists / Sudhansu Chokroverty, Eli S. Neiman, and Sushanth Bhat -- Sleep stages and scoring technique / Raman K. Malhotra and Alon Y. Avidan -- Sleep-disordered breathing and scoring / Robert J. Thomas, Sudhansu Chokroverty, and Sushanth Bhat -- Basic circadian rhythms and circadian sleep disorders / Roneil Malkani and Phyllis C. Zee -- Hypnogram analysis / Robert J. Thomas, Sudhansu Chokroverty, and Sushanth Bhat -- Sleep-related movements and scoring techniques / Birgit Hogl and Raffaele Ferri -- Cardiac arrhythmias / Robert J. Thomas, Sudhansu Chokroverty, and Sushanth Bhat -- Uncommon, atypical, and often unrecognized PSG patterns / Sudhansu Chokroverty, Sushanth Bhat, and Robert J. Thomas -- Motor disorders during sleep / Sudhansu Chokroverty, Marco Zucconi, Federica Provini, and Mauro Manconi -- Sleep and epilepsy / Marco Zucconi and Sudhansu Chokroverty -- Sleep dysfunction and sleep-disordered breathing in miscellaneous neurological disorders / Sudhansu Chokroverty, Sushanth Bhat, and Federica Provini -- Neuroimaging techniques / Thien Thanh Dang-Vu, Pierre Maquet, and Martin Desseilles -- Specialized techniques: multiple sleep latency testing / Sudhansu Chokroverty, Actigraphy / Sudhansu Chokroverty and Marco Zucconi, Recommendations for practical use of pulse transit time as a tool for respiratory effort measurements during sleep and microarousal recognition / Jean-Louis Pepin, Renaud Tamisier, and Patrick Levy, The cyclic alternating pattern / Mario Giovanni Terzano, Liborio Parrino, Fernando De Paolisi, and Elena Colizzi, Peripheral arterial tonometry / Robert J. Thomas, The electrocardiogram-spectrogram / Robert J. Thomas -- Positive pressure titration / Robert J. Thomas -- Oral appliances and surgical techniques for obstructive sleep apnea syndrome therapy / John A. Fleetham and Fernanda R. Almeida -- Pediatric polysomnography / Timothy F. Hoban.
Format
e-Book
Location
Online
Less detail

Atlas of sleep medicine

https://libcat.nshealth.ca/en/permalink/provcat32181
[edited by] Sudhansu Chokroverty, Robert J. Thomas. (Second edition) --Philadelphia: Saunders , c2014.
Available Online
View e-Book
Access
Registration required for PDF access.
Location
Online
Available Online
View e-Book
Author
Chokroverty, Sudhansu
Other Authors
Thomas, Robert J
Responsibility
[edited by] Sudhansu Chokroverty, Robert J. Thomas
Edition
Second edition
Place of Publication
Philadelphia
Publisher
Saunders
Date of Publication
c2014
Physical Description
1 online resource (xiii, 387 pages)
ISBN
9781455712687 (electronic bk.)
9781455712670
Subjects (MeSH)
Sleep Wake Disorders - diagnosis - Atlases
Polysomnography - Atlases
Subjects (LCSH)
Sleep
Sleep Disorders - diagnosis - Atlases
Polysomnography - Atlases
Contents
Polysomnographic recording technique / Sudhansu Chokroverty and Sushanth Bhat -- Electroencephalography for the sleep specialists / Sudhansu Chokroverty, Eli S. Neiman, and Sushanth Bhat -- Sleep stages and scoring technique / Raman K. Malhotra and Alon Y. Avidan -- Sleep-disordered breathing and scoring / Robert J. Thomas, Sudhansu Chokroverty, and Sushanth Bhat -- Basic circadian rhythms and circadian sleep disorders / Roneil Malkani and Phyllis C. Zee -- Hypnogram analysis / Robert J. Thomas, Sudhansu Chokroverty, and Sushanth Bhat -- Sleep-related movements and scoring techniques / Birgit Hogl and Raffaele Ferri -- Cardiac arrhythmias / Robert J. Thomas, Sudhansu Chokroverty, and Sushanth Bhat -- Uncommon, atypical, and often unrecognized PSG patterns / Sudhansu Chokroverty, Sushanth Bhat, and Robert J. Thomas -- Motor disorders during sleep / Sudhansu Chokroverty, Marco Zucconi, Federica Provini, and Mauro Manconi -- Sleep and epilepsy / Marco Zucconi and Sudhansu Chokroverty -- Sleep dysfunction and sleep-disordered breathing in miscellaneous neurological disorders / Sudhansu Chokroverty, Sushanth Bhat, and Federica Provini -- Neuroimaging techniques / Thien Thanh Dang-Vu, Pierre Maquet, and Martin Desseilles -- Specialized techniques: multiple sleep latency testing / Sudhansu Chokroverty, Actigraphy / Sudhansu Chokroverty and Marco Zucconi, Recommendations for practical use of pulse transit time as a tool for respiratory effort measurements during sleep and microarousal recognition / Jean-Louis Pepin, Renaud Tamisier, and Patrick Levy, The cyclic alternating pattern / Mario Giovanni Terzano, Liborio Parrino, Fernando De Paolisi, and Elena Colizzi, Peripheral arterial tonometry / Robert J. Thomas, The electrocardiogram-spectrogram / Robert J. Thomas -- Positive pressure titration / Robert J. Thomas -- Oral appliances and surgical techniques for obstructive sleep apnea syndrome therapy / John A. Fleetham and Fernanda R. Almeida -- Pediatric polysomnography / Timothy F. Hoban.
Access
Registration required for PDF access.
Format
e-Book
Location
Online
Less detail

Basic Principles of Cardiovascular MRI : Physics and Imaging Technique

https://libcat.nshealth.ca/en/permalink/provcat39379
Mushabbar A. Syed, Subha V. Raman, Orlando P. Simonetti, editors. (1st ed.) --Cham: Springer , c2015.
Available Online
View e-Book
Location
Online
This book is a comprehensive and authoritative text on the subject of cardiovascular magnetic resonance (CMR). Imaging experts from the most medically advanced areas of the world discuss the basic principles of this modality in detail while maintaining a focus on the needs of cardiovascular imagers who wish to learn more about this subject but do not have a strong background in physics. CMR is now considered a clinically important imaging modality for patients with a wide variety of cardiovascu…
Available Online
View e-Book
Other Authors
Syed, Mushabbar A
Raman, Subha V
Simonetti, Orlando P
Responsibility
Mushabbar A. Syed, Subha V. Raman, Orlando P. Simonetti, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xiv, 338 p. : 239 illus., 142 illus. in color)
ISBN
9783319221410
9783319221403 (print ed.)
Subjects (MeSH)
Cardiovascular Diseases - diagnostic imaging
Diagnostic Techniques, Cardiovascular
Radiography
Abstract
This book is a comprehensive and authoritative text on the subject of cardiovascular magnetic resonance (CMR). Imaging experts from the most medically advanced areas of the world discuss the basic principles of this modality in detail while maintaining a focus on the needs of cardiovascular imagers who wish to learn more about this subject but do not have a strong background in physics. CMR is now considered a clinically important imaging modality for patients with a wide variety of cardiovascular diseases. Recent developments have influenced a wide variety of cardiovascular imaging applications, many of which are now routinely used in clinical practice in CMR laboratories around the world. That it is non-invasive and lacks ionizing radiation exposure make CMR uniquely important for patients whose clinical condition requires serial imaging follow-up. Basic Principles of Cardiovascular MRI: Physics and Imaging Techniques includes a wealth of CMR examples in the form of high-resolution still images. Each imaging technique is discussed in separate chapters that include the physics and clinical applications (with cardiovascular examples) of that particular technique. As such, this book will be essential for cardiovascular medicine specialists and trainees , cardiovascular physicists, and clinical cardiovascular imagers.
Contents
[publisher supplied] MRI scanner and coils -- Signal generation -- k-space -- Pulse sequence -- Image acquisition -- Image resolution -- Fast imaging -- High field MRI (3 Tesla or higher) -- Artifacts -- MRI safety -- Gating -- Gradient echo and cine imaging -- Black blood imaging and tissue characterization -- Perfusion -- Stress testing -- Late gadolinium enhancement imaging (scar/fibrosis) -- Phase contrast flow -- Coronary imaging -- Spectroscopy -- Contrast media -- Contrast enhanced MRA -- Non-contrast enhanced MRA -- Advanced cardiovascular magnetic resonance techniques.
Format
e-Book
Location
Online
Less detail

Clinical gastrointestinal endoscopy

https://libcat.nshealth.ca/en/permalink/provcat31763
[edited by] Vinay Chandrasekhara, B. Joseph Elmunzer, Mouen A. Khashab ... [et al.]. (3rd ed.) --Philadelphia, PA: Elsevier , c2019.
Available Online
View e-Book
Access
Registration required for PDF access.
Location
Online
Now thoroughly up-to-date both in print and online, Clinical Gastrointestinal Endoscopy, 3rd Edition, by Drs. Vinay Chandrasekhara, Mouen Khashab, B. Joseph Elmunzer, and V. Raman Muthusamy, ensures that you stay current with the latest technology and techniques in GI endoscopy. An all-new editorial team, newly updated videos and images, and a reorganized format make this reference an easy-to-use source of reliable information on a full range of topics, including anatomy, pathophysiology, and …
Available Online
View e-Book
Other Authors
Chandrasekhara, Vinay
Responsibility
[edited by] Vinay Chandrasekhara, B. Joseph Elmunzer, Mouen A. Khashab ... [et al.]
Edition
3rd ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
c2019
Physical Description
1 online resource, 800 p.
ISBN
9780323415095
Subjects (MeSH)
Biliary Tract Diseases - therapy
Endoscopy, Gastrointestinal
Gastrointestinal Diseases - therapy
Pancreatic Diseases - therapy
Subjects (LCSH)
Enteroscopy
Gastroscopy
Endoscopy - methods
Gastrointestinal Diseases - diagnosis
Specialty
Endoscopy
Gastroenterology
Surgical Procedures, Operative
Abstract
Now thoroughly up-to-date both in print and online, Clinical Gastrointestinal Endoscopy, 3rd Edition, by Drs. Vinay Chandrasekhara, Mouen Khashab, B. Joseph Elmunzer, and V. Raman Muthusamy, ensures that you stay current with the latest technology and techniques in GI endoscopy. An all-new editorial team, newly updated videos and images, and a reorganized format make this reference an easy-to-use source of reliable information on a full range of topics, including anatomy, pathophysiology, and therapeutic management options, in addition to the latest GI procedures and technologies.
Access
Registration required for PDF access.
Format
e-Book
Location
Online
Less detail

Epilepsy : mechanisms, models and translational perspectives

https://libcat.nshealth.ca/en/permalink/provcat24389
Rho, Jong M. --Boca Raton, FL: CRC Press , 2010.
Call Number
WL 385 E641 2010
Location
Halifax Infirmary
Call Number
WL 385 E641 2010
Author
Rho, Jong M
Other Authors
Sankar, Raman
Strafstrom, Carl E
Place of Publication
Boca Raton, FL
Publisher
CRC Press
Date of Publication
2010
Physical Description
646 p.
ISBN
9781420085594
Subjects (MeSH)
Epilepsy - physiopathology
Epilepsy - therapy
Anticonvulsants - therapeutic use
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
Less detail

Filaggrin : basic science, epidemiology, clinical aspects and management

https://libcat.nshealth.ca/en/permalink/provcat33854
Jacob P. Thyssen, Howard I. Maibach, editors. --Heidelberg: Springer , c2014.
Available Online
View e-Book
Location
Online
Filaggrin proteins are expressed in several human tissues, including the skin, oral mucosa, conjunctivae, esophagus, cervix, and testes. While filaggrin guarantees both structural and functional normality of the human epidermis, its role in other tissues is largely unknown. Epidermal deficiency of filaggrin causes dry and scaly skin, but also strongly increases the risk of skin diseases, in particular ichthyosis vulgaris and atopic dermatitis. Importantly, the risk of related asthma, hay fever,…
Available Online
View e-Book
Other Authors
Thyssen, Jacob P.
Maibach, Howard I.
Responsibility
Jacob P. Thyssen, Howard I. Maibach, editors
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xv, 373 pages)
ISBN
9783642543791 (electronic bk.)
9783642543784
Subjects (MeSH)
Intermediate Filament Proteins
Subjects (LCSH)
Skin - Diseases - Genetic aspects
Medical genetics
Abstract
Filaggrin proteins are expressed in several human tissues, including the skin, oral mucosa, conjunctivae, esophagus, cervix, and testes. While filaggrin guarantees both structural and functional normality of the human epidermis, its role in other tissues is largely unknown. Epidermal deficiency of filaggrin causes dry and scaly skin, but also strongly increases the risk of skin diseases, in particular ichthyosis vulgaris and atopic dermatitis. Importantly, the risk of related asthma, hay fever, and food allergy is also increased although filaggrin is not expressed in the airways and gastrointestinal tract. Common FLG mutations, leading to reduced filaggrin expression, have mainly been identified in Europeans and Asians, reaching a prevalence of 5-10%. Even in the absence of atopic dermatitis, the skin of individuals with FLG mutations differs fundamentally from normal skin, for example by generating more vitamin D and allowing chemicals and allergens to more widely penetrate across the stratum corneum. This textbook provides comprehensive and detailed coverage of the effects of filaggrin and filaggrin gene (FLG) mutations in health and disease (cutaneous and non-cutaneous) and also discusses the basic science, epidemiology, management, and future research areas.
Contents
Part I. Basic Science -- Function of Filaggrin and Its Metabolites -- Morphology of Filaggrin-Depleted Epidermis -- Stratum Corneum Lipids and Filaggrin -- Inflammatory-Driven Depletion of Filaggrin Proteins -- Immune Activity and Vitamin D -- Filaggrin-2 -- Part II. Identification and Study Methods -- Animal Models -- In Vitro Models of Filaggrin-Associated Diseases -- Mapping Posttranslational Regulation of Filaggrin Using Phosphoproteomics -- Noninvasive Detection of Filaggrin Molecules by Raman Spectroscopy -- Filaggrin Genotyping -- Part III. Epidemiology and Environmental Exposures -- Prevalence of Filaggrin Gene Mutations: An Evolutionary Perspective -- Filaggrin Gene Mutations in Asian Races -- Filaggrin Gene Loss-of-Function Mutations and Exposure to Endocrine Disrupting Environmental Chemicals -- Part IV. Filaggrin and Atopic Disease -- Filaggrin Mutations and the Atopic March -- Atopic Dermatitis -- Asthma -- Filaggrin Mutations, Skin Barrier Dysfunction, and Sensitization in Allergic Rhinitis -- Filaggrin and Non-cutaneous Disease: Food Allergy -- Filaggrin in Canine Skin -- Part V. Filaggrin and Cutaneous Disease -- Ichthyosis Vulgaris and Other Disorders of Cornification -- Xerosis Means "Dry Skin": Mechanisms, Skin Conditions, and Its Management -- Allergic Contact Dermatitis -- Irritant Contact Dermatitis -- Hand Eczema -- Filaggrin in Psoriasis -- Filaggrin and Skin Infections -- Atopic Dermatitis and Skin Cancer -- Filaggrin Gene Mutations: A Clinician's Perspective -- Part VI. Filaggrin and Non-cutaneous Disease -- Filaggrin, the Skin Barrier, and Diabetes -- The Eye and Filaggrin -- Filaggrin Dysfunction and Its Association with Inflammatory Conditions of the GI Tract -- Filaggrin, Human Papillomavirus, and the Cervix -- Antibodies Against Citrullinated Proteins and Filaggrin -- Filaggrin and the Oral Mucosa -- Part VII. Management -- Therapeutics and Other Interventions.
Format
e-Book
Location
Online
Less detail

Health Care for People with Intellectual and Developmental Disabilities across the Lifespan

https://libcat.nshealth.ca/en/permalink/provcat39786
I. Leslie Rubin, Joav Merrick, Donald E. Greydanus,, editors Dilip R. Patel. ([3rd ed.]) --Cham: Springer , c2016.
Available Online
View e-Book
Location
Online
This book provides a broad overview of quality health care for people with intellectual and developmental disabilities (IDD). It focuses on providing the reader a practical approach to dealing with the health and well-being of people with IDD in general terms as well as in dealing with specific conditions. In addition, it offers the reader a perspective from many different points of view in the health care delivery system as well as in different parts of the world. This is the 3rd, and much exp…
Available Online
View e-Book
Other Authors
Rubin, I. Leslie
Merrick, Joav
Greydanus, Donald E
Patel, Dilip R
Responsibility
I. Leslie Rubin, Joav Merrick, Donald E. Greydanus,, editors Dilip R. Patel
Edition
[3rd ed.]
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (lx, 2307 p. : 266 illus., 170 illus. in color)
ISBN
9783319180960
9783319180953 (print ed.)
Subjects (MeSH)
Developmental Disabilities
Health Promotion
Health Services Accessibility
Mentally Disabled Persons
Abstract
This book provides a broad overview of quality health care for people with intellectual and developmental disabilities (IDD). It focuses on providing the reader a practical approach to dealing with the health and well-being of people with IDD in general terms as well as in dealing with specific conditions. In addition, it offers the reader a perspective from many different points of view in the health care delivery system as well as in different parts of the world. This is the 3rd, and much expanded edition, of a text that was first published by Rubin and Crocker in 1989 (Lea and Fibiger). The second edition was published by Rubin and Crocker in 2006 (Paul Brookes) and has been used as a formal required text in training programs for physicians, nurses and nurse practitioners as well as by administrators who are responsible for programs serving people with IDD. This book is considered the "Bible" in the field of health care for people with IDD since 1989 when the first edition came out.
Contents
Foreword; David Satcher -- Tribute to Allan Crocker; I. Leslie Rubin -- Introduction to the volume; I. Leslie Rubin -- Part I. Systems of Delivery Health Care -- Chapter 1. Introduction to Intellectual and Developmental Disabilities; Dilip R. Patel, Donald Greydanus, Joav Merrick and I. Leslie Rubin -- Chapter 2. Health is More Than Medicine; Donald J. Lollar and Randall A. Phelps -- Chapter 3. Health of Health Care for People with Intellectual and Developmental Disability; Wendy M. Nehring and Brandi Lindsey -- Chapter 4. Family Centered Care -- 4.1. Family Centered Care in a Health Care Setting; Catherine de Haas and Ruth Ryan -- 4.2. Siblings of Children and Adults with Intellectual and Developmental Disability; Monica McCaffrey -- 4.3. Grandparents as Caregivers for Grandchildren with Intellectual and Developmental Disabilities; LaShawnDa Pittman, Janice Nodvin and Maeve Howett -- 4.4. Aging Parents; Nancy S. Jokinen -- 4.5. Rights of Individuals with Disability to Parenthood; Karen McKenzie, Laura Shewan and Suzanne Wilson -- 4.6. Foster Care; Julie Dini -- 4.7. Transitioning Youth to Adult Health Care: A Person-Centered and Culturally Competent Approach; Stacey Ramirez, Staeshe Collins and Brenda Liz Mu©oz -- Chapter 5. Integrating Systems of Care for Individuals with Intellectual and Developmental Disabilities across the Lifespan; Georgina Peacock and Cheryl Rhodes -- Chapter 6. International Classification of Function; Margaret Kyrkou -- Chapter 7. Systems of Health Care Delivery -- 7.1. Clinical Settings for Health Care Delivery; Stephen B. Sulkes -- 7.2. Reaching the Unserved and Underserved: Medical Care in Rural and Urban Settings; Daniel Crimmins and Akilah Heggs -- 7.3. International Perspectives on the Delivery of Health Care; David OþHara -- 7.4. Health Care Financing; David Ervin -- 7.5. Systems of Health Care Delivery: Community Setting; Rosemary M. Caron -- 7.6. Models for Care for Children with Medical Complexity; Melinda Morin, Justin Alvey, Nancy Murphy and Laurie Glader -- 7.7. School Settings; Jeffrey Okamoto -- 7.8. Health Care Transition; David Wood, Linda R. Edwards and Brian Hennen -- 7.9. Community Healthcare; David A. Ervin and Brian Hennen -- 7.10. Nursing Home Settings; Nursing Home Settings; Sandra Friedman -- 7.11. Current and Emerging Trends for Residential Supports for Persons with Intellectual and Developmental Disabilities and the Impact of Managed Care Initiatives; James Conroy, Steven J. Dale and Robert McCaffrey -- 7.12. Large Residential Facilities; Norberto Alvarez -- 7.13. Community Nursing; Joan Earle Hahn and Laura E. Fox. 7.14. Medical Home; Liz Grier -- Chapter 8. Principles of Care and Ethics; Peter J. Smith -- Chapter 9. Practicalities of Care. 9.1. Practicalities of Care for Adults with Intellectual and Developmental Disabilities; Peter Lindsay and Matt Hoghton.' 9.2. Electronic Medical Records; Stephen B. Sulkes -- Chapter 10. Intellectual Disability and the Environment -- 10.1. The Environment; J. Carolyn Graff and Jeffrey A. Foran -- 10.2. Fetal Environment and Risks for Intellectual and Developmental Disabilities; I. Leslie Rubin -- Chapter 11. Built Environments for Improving Human Development and Promoting Health and Quality of Life; Chris Kochtitzsky and Michele Crachiola -- Chapter 12. Public Health Perspectives on Intellectual and Developmental Disabilities; Gloria L. Krahn and Michael H. Fox -- Chapter 13. International Perspectives -- 13.11. Systems of Delivery of Health Care for Persons with Developmental Disabilities: The Case of Belgium; Koen Hermans and Anja Declerq -- 13.2. Service for People with Intellectual Disability in the United Kingdom; Hardeep Uppal and Vee P. Prasher -- 13.3. People with Developmental Disabilities in the United States of America; Gloria L. Krahn and Lynda B. Bersani -- Chapter 13.4. Former Soviet Union; Naira Avetisyan -- 13.5. Health and Social Services for People with Intellectual and Developmental Disabilities in Taiwan; Kuo yu Wang -- 13.6. Intellectual Disability in India: Recent Trends in Care and Services; Satish C. Girimaji and John VS Kommu -- 13.7. Hong Kong, PRC; Ben MF Law and Daniel TL Shek -- 13.8. Israel; Joav Merrick and Mohammed Morad -- 13.9. Canada; Ian Casson, Theresa Broda, Jessica Jones, Alvin Loh, Bruce McCreary, Ullanda Niel and C. Ruth Wilson -- 13.10. Organization of Services and Life-Long Health Care: Japan; Shigeru Suemitsu and Susumu Uehara -- 13.11. Special-Needs Education, Special Care, and Education for Physicians in Finland; Markus Kaski -- 13.12. South America. A Service Example from Lima, Peru; Liliana Mayo and Judith M. LeBlanc -- 13.13. Status of Legislation and Services in Turkey across the Lifespan; Kerim M. Munir -- 13.14. Service Organization and Support for People with Intellectual and Developmental Disabilities in the Netherlands; Frans VPM Ewals and Sylvia A Huisman -- 13.15. International Perspectives: Chile; Rosario Moore, Patricia M Valenzuela, Maria A Paul and Macarena Lizama -- 13.16. Services for Persons with Intellectual and DEvelopmental Disabilities in Italy; Fabrizio Fea -- 13.17. Denmark. A Historic Journey; Joav Merrick, Peter Uldall and Jakob Volther -- 13.18. Service and Care in Australia; Robert W. Davis -- 13.19. Africa; I Leslie Rubin -- Part II. Clinical Care -- Chapter 14. Developmental and Functional Evaluation and Assessment; Dilip R. Patel and Cora M. Taylor -- Chapter 15. Communication with Patients, Parents and Other Caregivers; Sheridan Forster -- Chapter 16. Inborn Errors of Metabolism -- 16.1. Newborn Screening; Geoffrey R. DeTolve -- 16.2. The Mucopolysaccharoidoses; Robert Conway -- 16.3. The Sphingolipidoses; Robert Conway -- 16.4. Mitochondrial Disorders; Frances D. Kendall -- Chapter 17. Genetics and Genetic Syndromes.' 17.1. What is New in Genetics and Genomics?; Helga V. Toriello -- 17.2. Autism and Genetics; Helga V. Toriello -- 17.3. 22q11.2 Deletion Syndrome: A Paradigmatic Copy-Number-Variant (CNV) Disorder; Joseph F. Cubells -- 17.4. Genetic Counseling; Sarah L. Klemm and Jennifer Fulbright -- Chapter 18. Syndromes -- 18.1. Down Syndrome; Brian G. Skotko and Ariel Tenenbaum -- 18.2. Fragile X. Syndrome; Emma Hare, Reymundo Lozano, Lindsey Partington and Randi J. Hagerman -- 18.3. Rett Syndrome: Seeing the Way Forward; Alan K. Percy -- 18.4. Prader Willi Syndrome; Randell Alexander -- 18.5. Williams Syndrome; Elaine Pereira, Robert Marion and Barbara R. Pober -- 18.6. Angelman Syndrome; Donald E. Greydanus, Helen D. Pratt and Marlene Pryson -- 18.7. Smith-Magenis Syndrome; Donald E. Greydanus and Joav Merrick -- 18.8. Noonan Syndrome; Jacqueline A. Noonan -- 18.9. Phakomatoses; Bruce Korf -- 18.10. Spina Bifida; Robert A. Jacobs, Alexis Deavonport, Kathryn Smith and Alex Van Speybroeck -- 18.11. Fetal Alcohol Syndrome; Ariel Tenenbaum, Isaiah Wexler and Joav Merrick -- 18.12. Other Syndromes -- 18.12.1. Lowe Syndrome; Donald E. Greydanus, Helen D. Pratt and Marlene Pryson -- 18.12.2. Nager Syndrome; Donald E. Greydanus, Helen D. Pratt and Marlene Pryson -- 18.12.3. Sturge-Weber Syndrome; Donald E. Greydanus, Helen D. Pratt and Marlene Pryson -- 18.12.4. Klinefelter Syndrome; Vandana Raman -- 18.12.5. Cornelia de Lange Syndrome; Elizabeth Poplawski -- Chapter 19. Prematurity and Ist Consequences; I. Leslie Rubin -- Chapter 20. Cerebral Palsy; Sarah Winter -- Chapter 21. Neurological Disorder -- 21.1. Congenital Anomalies of the Brain; Ayelet Halevy, Osnot Konen and Aviva Mimouni-Bloch -- 21.2. Epilepsy; Norberto Alvarez -- 21.3. Sleep disorders; Norberto Alvarez -- 21.4. Movement Disorders; Paula D. Ravin -- 21.5. Dementia and AlzheimerÇÖs Disease; Norberto Alvarez -- 21.6. Peripheral Nerve Disorders; Norberto Alvarez -- Chapter 22. Physiatry and Function -- 22.1. Pediatric Aspects of Physiatry and Function; Joshua Vova and Maurice G. Sholas -- 22.2. Psychiatry and Function: Common Issues in Adults with Intellectual and Developmental Disabilities; Dale C. Strasser, Laura Jones and Mitchel Leavitt -- Chapter 23. Developmental Therapies and Functional Assistance -- 23.1. Allied Health Professionals; Meir Lotan -- 23.2. Occupational Therapy; Sharon A. Cermak and Ann E. Borreson -- 23.3. Physical Therapy; Priscilla S. Osborne and Meir Lotan -- 23.4. Speech Language Pathology: Supports to Communication; John M. Costello and Howard C. Shane -- Chapter 24. Health Promotion; James H. Rimmer and Kelly Hsieh -- Chapter 25. Orthopaedic Considerations; Karen M. Bovid and Dilip R. Patel -- Chapter 26. Dermatology; Brian P. Pollack, Leslie P. Lawley, Jenna Streicher, Jason Hadley and Jack L. Arbiser -- Chapter 27. Eye and Vision Care; Laura Gwatkin -- Chapter 28. Dentistry; Ilan Feldberg and Joav Merrick -- Chapter 29. Otolaryngology -- 29.1 Hearing Impairment; Peter Chung, Shibani Kanungo and Dilip R. Patel -- 29.2 Otolaryngology; Michael McWay and Colleen Dodich -- Chapter 30. Gastrointestinal Issues; Orhan Atay -- Chapter 31. Nutrition; Dawna Torres Mughal and Patricia Novak -- Chapter 32. Feeding Aspects; Laura Minando and Elana M Bern -- Chapter 33. Endocrine Issues; Rachel-Marie A. Cazeau and Manmohan K. Kamboj -- Chapter 34. Urological Concerns; Julian Wan -- Chapter 35. Cardiology -- 35.1 Congenital Heart Disease and Down Syndrome; Kenneth J. Dooley -- 35.2 Congenital Heart Disease; Shiva Sharma -- Chapter 36. Pulmonology, Sleep Disordered Breathing and Sleep Apnea; Charles A. McCaslin and John Norman Schuen -- Chapter 37. WomenÇÖs Health; Stephanie J. Stockburger and Hatim A. Omar -- Chapter 38. MenÇÖs Health; Joav Merrick and Mohammed Morad -- Chapter 39. Sexuality; Sorah Stein and Mitch Tepper -- Chapter 40. Cancer and Oncology; Walid Kaddan and Joav Merrick -- Chapter 41. Severe and Profound Intellectual Disability -- 41.1 Care; Margaret Kyrkou -- 41.2 Psychological Well-Being of Children and Adults with Severe and Profound Intellectual and Developmental Disabilities; Fleur-Michelle M Coiffait and Alexandra T Leedham -- Chap.
Format
e-Book
Location
Online
Less detail

In Vivo Cryotechnique in Biomedical Research and Application for Bioimaging of Living Animal Organs

https://libcat.nshealth.ca/en/permalink/provcat40408
Shinichi Ohno, Nobuhiko Ohno, Nobuo Terada, editors. (1st ed.) --Tokyo: Springer Japan , c2016.
Available Online
View e-Book
Location
Online
This book focuses on actual morphofunctional findings of cells and tissues in living animal organs. Medical and biological scientists need to know the real in vivo morphology and immunolocalization of the molecular components in living animal organs. Recently, the live imaging of cells and tissues of animals with fluorescence-labeled proteins by gene manipulation has become more and more popular in biological fields. Current research, meanwhile, has revealed that immunohistochemical or morpholo…
Available Online
View e-Book
Other Authors
Ohno, Shinichi
Ohno, Nobuhiko
Terada, Nobuo
Responsibility
Shinichi Ohno, Nobuhiko Ohno, Nobuo Terada, editors
Edition
1st ed.
Place of Publication
Tokyo
Publisher
Springer Japan
Date of Publication
c2016
Physical Description
1 online resource (xi, 300 p. : 114 illus., 99 illus. in color)
ISBN
9784431557234
9784431557227 (print ed.)
Subjects (MeSH)
Animal Structures - anatomy & histology
Biopsy - methods
Cryoelectron Microscopy - methods
Freeze Substitution - methods
Intravital Microscopy - methods
Mice - anatomy & histology
Abstract
This book focuses on actual morphofunctional findings of cells and tissues in living animal organs. Medical and biological scientists need to know the real in vivo morphology and immunolocalization of the molecular components in living animal organs. Recently, the live imaging of cells and tissues of animals with fluorescence-labeled proteins by gene manipulation has become more and more popular in biological fields. Current research, meanwhile, has revealed that immunohistochemical or morphological studies exclusively depend on living animal organs. The cryotechnique is one of the most useful tools for immunohistochemistry and bioimaging of animal organs. This book describes the epoch-making cryotechnique originally developed by the editors. The book also makes the management of living animal morphology more accessible not only for biomedical researchers but also for clinical doctors, providing a valuable resource work on the current perspectives of in vivo morphology.
Contents
Part I. Overview -- 1. Introduction -- 2. Biomedical significance and development of "IVCT" -- 3. How to perform "IVCT" -- 4. Technical merits with "IVCT" -- Part II. Application of "IVCT" to various mouse organs -- 5. Histochemical Analyses of Living Mouse Liver under Different Hemodynamic Conditions -- 6. Three-dimensional reconstruction of liver tissues with confocal laser scanning microscopy -- 7. Application of "in vivo cryotechnique" to immunohistochemical detection of hypoxia in mouse liver tissues treated with pimonidazole -- 8. Immunohistochemical detection of soluble immunoglobulins in small intestines -- 9. Detection of MAPK signal transduction proteins in an ischemia/reperfusion model of small intestines -- 10. Histological Study and LYVE-1 Immunolocalization of Mesenteric Lymph Nodes -- 11. Distribution of immunoglobulin-producing cells in immunized mouse spleens -- Chapter12. Alteration of erythrocyte shapes in various organs of living mice or under blood flow conditions -- 13. Dynamic ultrastructure of smooth muscle cells in dystrophin-deficient mdx or normal scn mice -- 14. Dynamic Bioimaging of Serum Proteins in Beating Mouse Hearts -- 15. Histochemical analyses and quantum dot imaging of microvascular blood flow with pulmonary edema -- 16. Dynamic ultrastructure of pulmonary alveoli of living mice under respiratory conditions -- 17. Immunohistochemical analysis of various serum proteins in living mouse thymus -- 18. Immuno- and enzyme-histochemistry of HRP for demonstration of blood vessel permeability in mouse thymic tissues -- 19. Immunolocalization of serum proteins in living mouse glomeruli under various hemodynamic conditions -- 20. Immunohistochemical Analyses on Albumin and IgG in Acute Hypertensive Mouse Kidneys -- 21. Application of novel "in vivo cryotechnique" in living animal kidneys -- 22. Application of periodic acid-Schiff fluorescence emission for imunohistochemistry of living mouse renal glomeruli -- 23. Immunohistochemical analyses on serum proteins in nephrons of protein-overload mice -- 24. Immunohistochemical analyses of serum proteins in puromycin aminonucleoside nephropathy of living rat kidneys -- 25. Immunolocalization of phospho-Arg-directed protein kinase-substrate in hypoxic kidneys -- 26. Dynamic ultrastructures of renal glomeruli in living mice under various hemodynamic conditions -- 27. Function of dynamin-2 in formation of discoid vesicles in urinary bladder umbrella cells -- 28. Involvement of follicular basement membrane and vascular endothelium in blood-follicle barrier formation of mice -- 29. Permselectivity of blood-follicle barriers in mouse polycystic ovary model -- 30. Application of "in vivo cryotechnique" to immunohistochemical study of serum albumin in normal and cadmium-treated mouse testis organs -- 31. Immunohistochemical detection of angiotensin II receptors in mouse cerebellum -- 32. Application of "in vivo cryotechnique" to immunohistochemical analyses for effects of anoxia on serum immunoglobulin and albumin leakage through blood-brain barrier in mouse cerebellum -- 33. Extracellular Space in Central Nervous System -- 34. Overview on recent applications of in vivo cryotechnique in neurosciences -- 35. Application of "in vivo cryotechnique" to immunohistochemical detection of phosphorylated rhodopsin in light-exposed retina of living mouse -- 36. Application of "in vivo cryotechnique" to immunohistochemical detection of glutamate in mouse retina inner segment of photoreceptors -- 37. Application of ǣin vivo cryotechniqueǥ to immunohistochemical study of mouse sciatic nerves under various stretching conditions -- Part III. Further preparation after "IVCT" -- 38. Freeze-substitution (FS) fixation method -- Part IV. Comments on advantages of "IVCT" -- 39. Cryotechniques and freeze-substitution for immunostaining of intranuclear antigens and fluorescence in situ hybridization -- 40. Replica immunoelectron microscopy for caveolin in living smooth muscle cells -- 41. Application of "in vivo cryotechnique" to detection of injected fluorescence-conjugated IgG in living mouse organs -- 42. Application of "in vivo cryotechnique" to visualization of microvascular blood flow in mouse kidney by quantum dot injection -- Part V. Direct detection of molecules by Raman microscopy -- 43. Application of "in vivo cryotechnique" to Raman microscopy of freeze-dried mouse eyeball-slice -- 44. Application of "in vivo cryotechnique" to detection of erythrocyte oxygen saturation in mouse blood vessels with confocal Raman cryomicroscopy -- Part VI. Future development for human pathology -- 45. Imaging of thrombosis and microcirculation in mouse lungs of initial melanoma metastasis -- 46. Differential distribution of blood-derived proteins in xenografted human adenocarcinoma tissues -- Part VII. New cryobiopsy invention -- 47. Morphological and Histochemical Analysis of Living Mouse Livers by New "Cryobiopsy" Technique -- 48. Recent Development of In Vivo Cryotechnique to Cryobiopsy for Living Animals -- Part VIII. Application of cryobiopsy for living animal tissues -- 49. Significance of cryobiopsy for morphological and immunohistochemical analyses of xenografted human lung cancer tissues and functional blood vessels -- 50. Immunolocalization of serum proteins in xenografted mouse model of human tumor cells -- 51. Histochemical approach of cryobiopsy for glycogen distribution in living mouse livers under fasting and local circulation loss conditions -- Part IX. New bioimaging of living animal tissues -- 52. Bioimaging of fluorescence-labeled mitochondria in subcutaneously grafted murine melanoma cells by the 'in vivo cryotechnique" -- 53. Application of "in vivo cryotechnique" to visualization of ATP with luciferin-luciferase reaction in mouse skeletal muscles -- 54. Concluding remarks.
Format
e-Book
Location
Online
Less detail

Management of Heart Failure. Volume 2, Surgical

https://libcat.nshealth.ca/en/permalink/provcat39678
Jai Raman, editor. (Second edition) --London: Springer , c2016.
Available Online
View e-Book
Location
Online
This book has been conceived as a rapid but comprehensive review for practitioners of all persuasions involved in the management of patients with heart failure. Heart failure is a problem of epidemic proportions in all parts of the world. State of the art treatment may not be accessible to all, but simply creating an awareness of simple methods of diagnosis and treatment would assist in promoting a better global response to this epidemic. This updated second edition, written by a panel of world…
Available Online
View e-Book
Other Authors
Raman, Jai
Responsibility
Jai Raman, editor
Edition
Second edition
Place of Publication
London
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xiii, 284 p. : 127 illus., 28 illus. in color)
ISBN
9781447142799
9781447142782 (print ed.)
Subjects (MeSH)
Heart Failure - surgery
Abstract
This book has been conceived as a rapid but comprehensive review for practitioners of all persuasions involved in the management of patients with heart failure. Heart failure is a problem of epidemic proportions in all parts of the world. State of the art treatment may not be accessible to all, but simply creating an awareness of simple methods of diagnosis and treatment would assist in promoting a better global response to this epidemic. This updated second edition, written by a panel of world-renown cardiology experts, focuses on the surgical management of heart failure. Surgery for heart failure is an evolving and new area in cardiac surgery with many exciting developments. Management of Heart Failure, Volume 2: Surgical will be essential reading for all specialists dealing with patients with or who are at risk of heart failure, including but not limited to cardiologists, emergency medicine physicians, critical care physicians, anesthesiologists, interventionalists and cardiothoracic surgeons.
Contents
1. Surgical Perspectives -- 2. Pathophysiology—Clinical Spectrum and Current Management -- 3. Strategies in Surgical Management -- 4. Advanced Heart Failure: Transplant vs Nontransplant Surgical Options -- 5. Transplantation for End-Stage Heart Disease -- 6. OPCAB Treatment for Heart Failure -- 7. Circulatory Support for Bridging to Recovery or Transplantation -- 8. Left Ventricular Reconstruction in Ischemic Cardiomyopathy -- 9. Modifications of the Dor Procedure and Failure Modes of the Procedure -- 10 Mitral Valve Repair -- 11. Destination Therapy with Permanent Mechanical Circulatory Assist Devices -- 12. Enabling Techniques and Technologies -- 13. Catheter-Based and Surgical Therapy for Ventricular Tachycardia -- 14. Catheter Ablation for Atrial Fibrillation in Patients with Heart Failure -- 15. Surgical Therapy for Atrial Fibrillation -- 16. Pacing Therapies, Defibrillators, and Post-Operative Arrhythmias -- 17. Ventricular Containment, Shape Change, and Infarct Restraint -- 18. Other Techniques in Special Circumstances: Pulmonary Thromboendarterectomy in Right Heart Failure -- 19. Surgical Management of Pediatric Heart Failure and Heart Failure due to Congenital Heart Disease -- 20. Anesthetic Management and Hemodynamic Management -- 21. Perioperative and ICU Care, Fluid Management, and Renal Support -- 22. New Therapies and What Is on the Horizon.
Format
e-Book
Location
Online
Less detail

Non invasive diagnostic techniques in clinical dermatology

https://libcat.nshealth.ca/en/permalink/provcat33817
Enzo Berardesca, Howard Maibach, Klaus Wilhelm, editors. --Heidelberg: Springer , c2014.
Available Online
View e-Book
Location
Online
This book is a comprehensive but compact guide to the latest technical and technological developments in the growing field of non invasive diagnosis in clinical dermatology. Information is provided on the practical and technical characteristics of a wide range of equipment and methods for in vivo measurements that aid in the investigation of skin function, the evaluation of topically applied products, and the monitoring of skin disease. Individual sections are devoted to imaging techniques, ski…
Available Online
View e-Book
Other Authors
Berardesca, Enzo
Maibach, Howard I.
Wilhelm, Klaus-Peter
Responsibility
Enzo Berardesca, Howard Maibach, Klaus Wilhelm, editors
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (x, 479 pages)
ISBN
9783642321092 (electronic bk.)
9783642321085
Subjects (MeSH)
Diagnostic Techniques and Procedures
Skin Diseases - diagnosis
Subjects (LCSH)
Skin - Diseases - Diagnosis
Skin - Examination
Diagnosis, Noninvasive
Abstract
This book is a comprehensive but compact guide to the latest technical and technological developments in the growing field of non invasive diagnosis in clinical dermatology. Information is provided on the practical and technical characteristics of a wide range of equipment and methods for in vivo measurements that aid in the investigation of skin function, the evaluation of topically applied products, and the monitoring of skin disease. Individual sections are devoted to imaging techniques, skin analysis, superficial skin analysis, skin mechanics, water and stratum corneum hydration, and erythema and blood flow.
Contents
Part I. Imaging Techniques -- 1. Use of Videodermatoscopy in Dermatology -- 2. Visioscan-Driven ULEV Method -- 3. Optical Coherence Tomography -- 4. PRIMOS 3D Digital Frame Projection -- 5. FOITS (Fast Optical In Vivo Topometry of Human Skin) -- 6. In Vivo Confocal Microscopy in Skin Oncology -- 7. In Vivo Reflectance Confocal Microscopy for Inflammatory Skin Diseases’ Assessment -- 8. In Vivo Reflectance Confocal Microscopy for Oral Mucosa Assessment -- 9. Multiphoton Laser Microscopy and Fluorescence Lifetime Imaging for the Assessment of the Skin -- 10. Application of Laser Scanning Microscopy in Dermatology and Cutaneous Physiology -- 11. Telethermography -- 12. Capillaroscopy -- 13. Sonography of the Skin -- 14. New Ultrasound Techniques in Clinical Dermatology -- 15. Multimodal Magnetic Resonance Imaging of the Human Skin -- 16. Skin Capacitance Imaging -- 17. Tissue Viability Imaging for Assessment of Skin Erythema and Blanching -- Part II. Skin Analysis -- 18. Interaction Between Free Radicals and Antioxidants in Human Skin -- 19. Raman Spectroscopy -- 20. Imaging Drug Delivery to Skin with Coherent Raman Scattering Microscopy -- 21. Assessment of Mechanical Properties of Skin by Shearwave Propagation and Acoustic Dispersion -- Part III. Superficial Skin Analysis -- 22. Cyanoacrylate Skin Surface/Follicular Stripping -- 23. Corneosurfametry and Corneoxenometry -- 24. Sebumetry and Sebumtape -- 25. Biophysical Assessment of Skin Desquamation and Scaliness Using Tape Strips and Adhesive Discs -- 26. Stripping Techniques: Tape Stripping -- 27. Stratum Corneum Quantification -- 28. Utilisation of Infrared Densitometry in Stratum Corneum Research -- Part IV. Skin Mechanics -- 29. Cutometer® -- 30. Ballistometer -- Part V. Water and Stratum Corneum Hydration -- 31. TEWL, Closed-Chamber Methods: AquaFlux and VapoMeter -- 32. Transepidermal Water Loss (TEWL) -- 33. Skin Capacitance -- Part VI. Erythema and Blood Flow -- 34. The Use of Visual Grading Scales in Evaluating Skin Irritation and Sensitization: A Historical Perspective -- 35. Surface Skin Temperature in Tests for Irritant Dermatitis -- 36. Measurements of Lymph Flow -- Part VII. Hair and Follicles -- 37. Digital Imaging for Measuring of Hair Growth on the Human Scalp -- 38. Tensile Properties of Hair -- 39. Use of Videodermatoscopy in Scalp Disorders -- Part VIII. Nails -- 40. Nail Surface Topography and Onychochronobiology -- 41. Combined Technology for Measuring Skin Diseases with Molecular Imaging.
Format
e-Book
Location
Online
Less detail

Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin : Methodology and General Considerations

https://libcat.nshealth.ca/en/permalink/provcat41892
Nina Dragicevic, Howard I. Maibach, editors. --Berlin, Heidelberg: Springer , 2017.
Available Online
View e-Book
Location
Online
Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered, and the latest findings are provided on skin structure…
Available Online
View e-Book
Other Authors
Dragicevic, Nina
I. Maibach, Howard
Responsibility
Nina Dragicevic, Howard I. Maibach, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xvi, 414 pages) : 126 illus., 50 illus. in color
ISBN
9783662532706
9783662532683 (print ed.)
Subjects (MeSH)
Administration, Cutaneous
Drug Delivery Systems
Pharmaceutical Preparations - administration & dosage
Skin Absorption - drug effects
Abstract
Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered, and the latest findings are provided on skin structure and function, mathematics in skin permeation, and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners, students and dermatological scientists or dermatologists .
Contents
Part I: Factors Influencing Percutaneous Drug Penetration -- 1. Basic Mathematics in Skin Absorption -- 2. Occlusive Versus Nonocclusive Application in Transdermal Drug Delivery -- 3. Finite and Infinite Dosing -- 4. Non-formulation Parameters That Affect Penetrant-SkinVehicle Interactions and Percutaneous Absorption -- 5. The Influence of Emollients on Dermal and Transdermal Drug Delivery -- 6. The Effects of Vehicle Mixtures on Transdermal Absorption: Thermodynamics, Mechanisms, Assessment, and Prediction -- 7. Mechanistic Studies of Permeation Enhancers -- 8. High Throughput Screening of Transdermal Penetration Enhancers: Opportunities, Methods, and Applications -- Part II: Methods for Measuring the Percutaneous Drug Penetration -- 9. Models, Methods, and Measurements in Transdermal Drug Delivery -- 10. Human Native and Reconstructed Skin Preparations for In Vitro Penetration and Permeation Studies -- 11. Stripping Procedures for Penetration Measurements of Topically Applied Substances -- 12. Application of EPR-spin Probes to Evaluate Penetration Efficiency, Storage Capacity of Nanotransporters, and Drug Release -- 13. Confocal Raman Spectroscopy as a Tool to Investigate the Action of Penetration Enhancers Inside the Skin -- 14. ATR-FTIR Spectroscopy and the Skin Barrier: Evaluation of Penetration-Enhancement Effects -- 15. Confocal Microscopy for Visualization of Skin Penetration -- 16. Clinical Cutaneous Drug Delivery Assessment Using Single and Multiphoton Microscopy -- 17. Corneoxenometry: A Bioassay Exploring Skin Barrier Breaching -- Part III: The Retardation of Percutaneous Drug Penetration -- 18. Retardation Strategies for Sunscreen Agents -- 19. Retardation of Dermal Release by Film Forming Emulsions -- Part IV: Current Status of Dermal and Transdermal Drug Delivery -- 20. Penetration-Enhancement Strategies for Dermal and Transdermal Drug Delivery: An Overview of Recent Research Studies and Patents -- 21. Perspectives on Dermal Delivery of Macromolecular Drugs -- 22. Active Enhancement Methods in Transdermal Drug Delivery: Current Status and Future Perspectives -- Part V: Safety Issues and Ethics in Studies on Dermal and Transdermal Delivery -- 23. Efficacy, Safety and Targets in Topical and Transdermal Active and Excipient Delivery -- 24. Ethical Considerations in Research Involving Dermal and Transdermal Drug Delivery.
Format
e-Book
Location
Online
Less detail

Sleepy or Sleepless : Clinical Approach to the Sleep Patient

https://libcat.nshealth.ca/en/permalink/provcat39307
Raman K. Malhotra, editor. (1st ed.) --Cham: Springer , c2015.
Available Online
View e-Book
Location
Online
This concise text takes a symptom-based approach to evaluate and treat sleep disorders. Divided into two sections, this book emphasizes practical information in the patient history and physical, the latest screening techniques and common sleep disorders that either cause sleepiness, insomnia, or restless sleep. Chapters cover the epidemiology, pathophysiology, diagnosis and treatment of major sleep disorders and incorporate new classification systems from the International Classifications of Sl…
Available Online
View e-Book
Other Authors
Malhotra, Raman K
Responsibility
Raman K. Malhotra, editor
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xv, 213 p. : 23 illus., 17 illus. in color)
ISBN
9783319180540
9783319180533 (print ed.)
Subjects (MeSH)
Sleep Wake Disorders - diagnosis
Sleep Wake Disorders - therapy
Sleep - physiology
Abstract
This concise text takes a symptom-based approach to evaluate and treat sleep disorders. Divided into two sections, this book emphasizes practical information in the patient history and physical, the latest screening techniques and common sleep disorders that either cause sleepiness, insomnia, or restless sleep. Chapters cover the epidemiology, pathophysiology, diagnosis and treatment of major sleep disorders and incorporate new classification systems from the International Classifications of Sleep Disorders, 3rd Edition and the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Sleepy or Sleepless provides a solid foundation to clinicians who want to better evaluate patients with sleep-related complaints.
Contents
Part I. The Sleepy Patient -- 1. Key History and Physical Examination Findings in the Sleepy Patient -- 2. Diagnostic Tools and Testing in the Sleepy Patient -- 3. Sleep-Related Breathing Disorders -- 4. Central Nervous System Hypersomnias -- 5. Sleepiness in High Consequence Industries -- 6. Sleep Deprivation -- 7. The Sleepy Child -- Part II. The Sleepless or Restless Patient -- 8. Key History and Physical Examination Findings for the Sleepless or Restless Patient -- 9. Diagnostic Tools and Testing in the Sleepless and Restless Patient -- 10. Assessment and Management of Insomnia -- 11. Sleepless Patient: Circadian Rhythm Sleep-Wake Disorders -- 12. Restless Legs Syndrome: The Devil is in the Details -- 13. The Parasomnias -- 14. The Sleepless Child -- 15. Sleepless During and After Pregnancy.
Format
e-Book
Location
Online
Less detail

Technology in Practical Dermatology : Non-Invasive Imaging, Lasers and Ulcer Management

https://libcat.nshealth.ca/en/permalink/provcat45292
edited by Michele Fimiani, Pietro Rubegni, Elisa Cinotti. --Cham: Springer , c2020.
Available Online
View e-Book
Location
Online
This book provides a complete overview on the latest available technologies in dermatology, while discussing future trends of this ever-growing field. This handy guide provides clinicians and researchers with a clear understanding of the advantages and challenges of laser and imaging technologies in skin medicine today. It also includes a section on imaging techniques for the evaluation of skin tumors, with chapters devoted to dermoscopy, in vivo and ex vivo reflectance confocal microscopy, hig…
Available Online
View e-Book
Other Authors
Fimiani, Michele
Rubegni, Pietro
Cinotti, Elisa
Responsibility
edited by Michele Fimiani, Pietro Rubegni, Elisa Cinotti.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xviii, 500 p.) : 242 illus., 233 illus. in color
ISBN
9783030453510
9783030453503 (Print ed.)
9783030453527 (Print ed.)
9783030453534 (Print ed.)
Subjects (MeSH)
Laser Therapy - methods
Microscopy - methods
Skin Diseases - diagnostic imaging
Wounds and Injuries - therapy
Specialty
Dermatology
Diagnostic Imaging
Laser Therapy
Abstract
This book provides a complete overview on the latest available technologies in dermatology, while discussing future trends of this ever-growing field. This handy guide provides clinicians and researchers with a clear understanding of the advantages and challenges of laser and imaging technologies in skin medicine today. It also includes a section on imaging techniques for the evaluation of skin tumors, with chapters devoted to dermoscopy, in vivo and ex vivo reflectance confocal microscopy, high frequency ultrasound, optical coherence tomography, and a closing part on latest approaches to wound management. Completed by over 200 clinical images, Current Technology in Practical Dermatology: Non-Invasive Imaging, Lasers and Ulcer Management is both a valuable tool for the inpatient dermatologist and for physicians, residents, and medical students in the field.
Contents
Part I. Imaging techniques for the evaluation of skin diseases -- 1. Dermoscopy: fundamentals and technology advances -- 2. Dermoscopy for benign melanocytic skin tumors -- 3. Dermoscopy for melanoma -- 4. Dermoscopy for non-melanocytic benign skin tumors -- 5. Demoscopy for non-melanocytic malignant skin tumors -- 6. Dermoscopy for inflammatory diseases -- 7. Dermoscopy for infectious diseases -- 8. Digital dermoscopy analysis -- 9. Optical super-high magnification dermoscopy -- 10. Fluorescence videodermoscopy -- 11.Total body photography and sequential digital dermoscopy for melanoma diagnosis -- 12. History and fundamentals of reflectance confocal microscopy -- 13. In vivo reflectance confocal microscopy for benign melanocytic skin tumors -- 14. In vivo reflectance confocal microscopy for melanoma -- 15. In vivo reflectance confocal microscopy for non melanocytic benign skin tumors -- 16. In vivo reflectance confocal microscopy for non melanocytic malignant skin tumours -- 17. In vivo reflectance confocale microscopy for inflammatory diseases -- 18. In vivo reflectance confocal microscopy for infectious diseases -- 19. In vivo reflectance confocal microscopy for mucous membranes -- 20. Ex vivo confocal microscopy -- 21. Ultrasound -- 22. Optical coherence tomography -- 23. High-definition optical coherence tomography -- 24. 3D imaging -- 25. Raman spectroscopy -- 26. Multispectral and hyperspectral imaging for skin acquisition and analysis -- 27. Electrical impedance in dermatology -- Part II. Lasers and light sources technologies in dermatology -- 28. Laser light and light-tissue interaction -- 29. Laser and light sources: safety and organization issues -- 30. Intense polichromatic lights and light emitting diodes: what's new -- 31. Vascular lasers: tips and protocols -- 32. Broadband intense pulsed lights for vascular malformations -- 33. Pigment specific lasers for benign skin lesions and tattoos: long pulsed, nanosecond and picosecond lasers -- 34. Skin resurfacing: ablative and non-ablative lasers -- 35. Photorejuvenation: concepts, practice, perspectives -- 36. Laser hair removal: updates -- 37. Biophotonic therapy induced photobiomodulation -- 38. Photodynamic therapy -- Part III. Technological advances in wound management -- 39. Temporary dressing -- 40. Extracellular matrices -- 41. Skin bank bioproducts: the basics -- 42. Clinical applications of skin bank bioproducts -- 43. Negative pressure wound therapy -- 44. Tissue-engineered skin substitutes -- 45. Biologics in wound management -- 46. Stem cell in wound healing -- Part IV. New complementary tools for dermatologic diagnosis -- 47. Microbiopsy in dermatology -- 48. Noninvasive genetic testing: adhesive patch-based skin biopsy and buccal swab -- 49. Liquid biospsies.
Format
e-Book
Location
Online
Less detail

Textbook of Aging Skin

https://libcat.nshealth.ca/en/permalink/provcat41876
Miranda A. Farage, Kenneth W. Miller, Howard I. Maibach, editors. (Second edition) --Berlin, Heidelberg: Springer , c2017.
Available Online
View e-Book
Location
Online
This comprehensive book presents the latest information on all aspects of the aging skin, including a broad spectrum of the relevant basic science, malignant and non-malignant age-associated diseases and conditions, techniques and methods, toxicological and safety considerations in the elderly, psychological and social issues, ethnicity and gender differences and marketing to the aged. Since the first edition the book has been extensively updated and revised, with the inclusion of many addition…
Available Online
View e-Book
Other Authors
Farage, Miranda A.
Miller, Kenneth W.
Maibach, Howard I.
Responsibility
Miranda A. Farage, Kenneth W. Miller, Howard I. Maibach, editors
Edition
Second edition
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2017
Physical Description
1 online resource (xlvii, 2222 pages) : 573 illus., 424 illus. in color
Series Title
Springer reference
ISBN
9783662473986
9783662473979 (print ed.)
Subjects (MeSH)
Skin Aging
Notes
"eReference"--Publisher.
Abstract
This comprehensive book presents the latest information on all aspects of the aging skin, including a broad spectrum of the relevant basic science, malignant and non-malignant age-associated diseases and conditions, techniques and methods, toxicological and safety considerations in the elderly, psychological and social issues, ethnicity and gender differences and marketing to the aged. Since the first edition the book has been extensively updated and revised, with the inclusion of many additional chapters that describe the most recent advances in scientific, medical and technical understanding of the aging phenomenon. There is, for example, extended coverage of physiology, description of novel bioengineering methods and tools, detailed consideration of developments in genomics research, and information on new ingredients and products. Textbook of Aging Skin is written by global experts and thought leaders and is intended to serve as the single and complete reference on the subject. It will be of value for dermatologists, gerontologists, toxicologists, biologists and a range of other professionals.
Contents
Adipose-Derived Stem Cells and Their Secretory Factors for Skin Aging and Hair Loss -- Advanced Age Pruritus -- Age-Induced Hair Graying and Oxidative Stress -- Age-Related Morphometric Changes of Inner Structures of the Skin -- Assessed by In Vivo Reflectance Confocal Microscopy -- Age-related changes in skin mechanical properties -- Aging Genital Skin and Hormone Replacement Therapy Benefits -- Aging and Melanocytes Stimulating Cytokine Expressed by Keratinocyte and Fibroblast -- Aging of Epidermal Stem Cells -- Appearance and Internal Aging -- Basophilic (Actinic) Degeneration of the Dermis: An Easy Histological Scoring Approach in Dermal Photo-Aging -- Biology of Stratum Corneum: Tape Stripping and Protein Quantification -- Buffering Capacity Considerations in the Elderly -- Changes in Nail in the Aged -- Changes in the Composition of the Cornified Envelope During Skin Aging: A Calcium Centric Point of View -- Cluster of Differentiation 1d (CD1d) and Skin Aging -- Considerations for Thermal Injury: The Elderly as a Sensitive Population -- Corneocyte Size and Cell Renewal: Effects of Aging and Sex Hormones -- Cyanoacrylate Skin Surface Strippings -- Degenerative Changes in Aging Skin -- Facial Skin Rheology -- Histology of Microvascular Aging of Human Skin -- Hyaluronan and the Process of Aging in Skin -- Impact of Dietary Supplements on Skin Aging -- Influence of Exogenous Factors on Skin Aging -- Major Changes in Skin Function in the Elderly and Their Contributions to Common Clinical Challenges -- Neurotrophins and Skin Aging -- Overview of the histology of aging skin in laboratory models -- Pathology of Aging Skin -- Pathomechanisms of Endogenously Aged Skin -- Pathomechanisms of Photoaged Skin -- Peroxisome Proliferator-Activated Receptors: Role in Skin Health and Appearance of Photoaged Skin -- Physiological Variations During Aging -- Platinum and Palladium Nanoparticles Regulate the Redox Balance and Protect Against Age-Related Skin Changes in Mice -- Possible Involvement of Basement Membrane Damage by Matrix Metalloproteinases, Serine Proteinases and Heparanase in Skin Aging Process -- Proteoglycans in Skin Aging -- Skin Aging and Health -- Skin Aging: A Brief Summary of Characteristic Changes -- Skin Aging: An Immunohistochemical Evaluation -- Stratum Corneum Cell Layers -- The Extracellular Matrix Protein 1 (ECM1) in Molecular-Based Skin Biology -- The Genetics of Skin Aging -- The Stratum Corneum and Aging -- Unique Skin Immunology of the Lower Female Genital Tract with Age -- Vaginal Secretions with Age -- arNOX: A New Source of Aging -- arNOX: New Mechanisms of Skin Aging and Lipoprotein Oxidation -- Alterations of Energy Metabolism in Cutaneous Aging -- Cellular Energy Metabolism and Oxidative Stress -- Cutaneous Oxidative Stress and Aging -- DNA Damage and Repair in Skin Aging -- Fibulin-5 Deposition in Human Skin: Decrease with Aging and UVB Exposure and Increase in Solar Elastosis -- Aging and Intrinsic Aging: Pathogenesis and Manifestations -- Biological Effects of Estrogen on Skin -- Climate Change and its Dermatologic Impact on Aging Skin -- Cutaneous Responses to Tropospheric Ozone Exposure -- DNA Biomarkers in Aging Skin -- Environmental and Genetic Factors in Facial Aging in Twins -- Infrared A-Induced Skin Aging -- Infrared Radiation: Mechanisms, Implications, and Protection -- Perimenopausal Aging and Oral Hormone Replacement Therapy -- Sebum Production -- Skin Photodamage Prevention: State of the Art and New Prospects.-Tobacco Smoke and Skin Aging* -- Aging skin as a diagnostic tool for internal diseases: A chance for dermatology -- Aging-Associated Non-Melanoma Skin Cancer: A Role for the Dermis -- Atopic Dermatitis in the Aged -- Carcinogenesis: UV Radiation -- Control of Skin Blood Flow -- Cutaneous Effects and Sensitive Skin with Incontinence in the Aged -- Dry Skin in Diabetes Mellitus and in Experimental Models of Diabetes -- Facial Wrinkling: The Marquee Clinical Sign of Aging Skin.-Hyperpigmentation in Aging Skin -- Impaired Wound Repair and Delayed Angiogenesis -- Influence of Race, Gender, Age and Diabetes on Blood Flow -- Melanoma and Skin Aging -- Neoplastic Skin Lesions in the Elderly Patient -- Non-neoplastic Disorders of the Aging Skin -- Non-surgical Modalities of Treatment for Primary Cutaneous Cancers -- Pigmentation in Ethnic Groups -- Psoriasis and Aging.-Skin Aging and Cellulite in Women -- Skin Itch in the Elderly -- Sunlight Exposure and Skin Thickness -- Measurements as a Function of Age: Risk Factors for Melanoma -- The New Face of Pigmentation and Aging -- Aging and Senescence of Skin Cells in Culture -- Animal Models -- Assessing Quality of Life in Older Adult Patients with Skin Disorders -- Bioengineering Methods and Skin Aging -- Corneocyte Analysis -- Glycation and Skin aging -- Hydration of the Skin Surface -- In Vitro Method to Visualize UV-Induced Reactive Oxygen Species in a Skin Equivalent Model -- Molecular Concentration Profiling in Skin Using Confocal Raman Spectroscopy -- New Insights in Photoaging Process Revealed by In Vitro Reconstructed Skin Models -- Probiotics in Aging Skin -- Reconstructed Skin to Create in vitro Flexible Models of Skin Aging: New Results and Prospects -- Reflectance confocal microscopy and aging -- Skin Aging: A Generalization of the Micro-inflammatory Hypothesis -- Skinomics: A New Toolbox to Understand Skin Aging -- Structure of Stratum Corneum Lipid Studied by Electron Paramagnetic Resonance -- The Measurement and Perception of Uneven Coloration in Aging Skin -- The Potential of Probiotics and Prebiotics for Skin Health -- The Structural and Functional Development of Skin During the First Year of Life: Investigations Using Noninvasive Methods -- Transepidermal Water Loss in Young and Aged Healthy Humans -- Aging Skin Microbiology -- Application of In Vitro Methods in Preclinical Safety Assessment of Skin Care Products -- Dermal Safety Evaluation: Use of Disposable Diaper Products in the Elderly -- Irritant Contact Dermatitis -- Percutaneous Penetration of Chemicals and Aging Skin -- Safety Evaluation in the Elderly Via Dermatological Exposure -- Susceptibility to Irritation in the Elderly -- The Vaginal Microbiota in Menopause -- Genetic Basis of Healthy Skin Aging -- Genodermatoses with Premature Aging/Syndromes -- Resetting Skin Genome Back to Health Naturally with GHK -- Assessing Quality of Ordinal Scales Depicting Skin Aging Severity -- The Baumann Skin Typing System -- Aging Skin: Nourishing from Out-In. Lessons from Wound Healing -- Aging Skin: Nourishing from the Inside Out, Effects of Good Versus Poor Nitrogen Intake on Skin Health and Healing -- Discovering the link between nutrition and skin aging -- Preventive Skin Care During Skin Aging -- Advanced Glycation End Products (AGEs): Emerging Mediators of Skin Aging -- Aging Skin: Some Psychosomatic Aspects -- Psychological and Social Implications of Aging Skin: Normal Aging and the Effects of Cutaneous Disease -- Facial Skin Attributes and Age Perception -- The Neuroscience of Age Perception -- Aging in Asian Skin -- Determinants in the Rate of Skin Aging: Ethnicity, Gender, and Lifestyle Influences -- Gender Differences in Skin -- Effects of Aging on Skin Reactivity -- Perceptions of Sensitive Skin with Age -- Skin Reactivity of the Human Face: Functional Map and Age Related Differences -- Aging and Anti-Aging Strategies -- Antiaging Effects of Algae-Derived Mycosporine-Like Amino Acids (MAAs) on Skin -- Changes in Vulvar Physiology and Skin Disorders with Age and Benefits of Feminine Wipes in Postmenopausal Women -- Cosmetic Anti-Aging Ingredients -- Cosmetics and Aging Skin -- Influence of aging on sensorial perception of skin care products -- Innovative Nutraceutical Approaches to Counteract the Signs of Aging -- Long-Term Estrogen Effects on Sun-Exposed Human Skin -- Neck Rejuvenation with Fractional CO2 Laser -- Solutions and Products for Managing Female Urinary Incontinence -- The Role of Neuropeptides in Skin Wound Healing -- Therapeutic alternatives for the treatment of epidermal aging -- Topical Growth Factors for Skin Rejuvenation -- Topical Peptides and Proteins for Aging Skin -- Wound Healing as We Age -- A New Paradigm for the Aging Face -- Botulinum Toxin Type A and Laser Resurfacing Provide Adjunctive Benefit to Skin Aging -- Bridging Science and Beauty -- Cosmetic Surgery in the Elderly -- Elderly Face No Added Risk from Cosmetic Surgery -- Facial Rejuvenation: A Chronology of Procedures -- Punctural Face Rejuvenation -- Update on Asian Eyelid Anatomy and Periocular Aging Change -- Brain-Skin Connection: Impact of Psychological Stress on Skin -- Place your bets, the die is cast - The skin at the retiring age today and tomorrow -- Sleep and Aging Skin -- Unified Mind/Body for a Healthy Aging Skin -- Key Trends Driving Anti-Aging Skin Care in 2009 and Beyond -- Marketing and Product Design of Anti-Aging Skin Care Products.
Format
e-Book
Location
Online
Less detail